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Submissions from 2020

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Transcriptional dysregulation in developing trigeminal sensory neurons in the LgDel mouse model of DiGeorge 22q11.2 Deletion Syndrome., Thomas M. Maynard, Anelia Horvath, James Bernout, Beverly A. Karpinski, Andre L P Tavares, Ankita Shah, Qianqian Zheng, Liam Spurr, Jacqueline Olender, Sally A. Moody, Claire M. Fraser, Anthony-S LaMantia, and Norman H. Lee

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Combining DNMT and HDAC6 inhibitors increases anti-tumor immune signaling and decreases tumor burden in ovarian cancer., Sara Moufarrij, Aneil Srivastava, Stephanie Gomez, Melissa Hadley, Erica Palmer, Paul Tran Austin, Sarah Chisholm, Kyle Roche, Angela Yu, Jing Li, Wenge Zhu, Micael Lopez-Acevedo, Alejandro Villagra, and Katherine B. Chiappinelli

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Estimating the Allele-Specific Expression of SNVs From 10× Genomics Single-Cell RNA-Sequencing Data., Prashant N. M, Hongyu Liu, Pavlos Bousounis, Liam Spurr, Nawaf Alomran, Helen Ibeawuchi, Justin Sein, Dacian Reece-Stremtan, and Anelia Horvath

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Testing the "Grandma Hypothesis": Characterizing Skin Microbiome Diversity as a Project-Based Learning Approach to Genomics., Marcos Pérez-Losada, Kelly M Crandall, and Keith A. Crandall

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A Tale of Two Nineteenth-century Dutch Jewish Hospitals-One a Success, The Other a Failure., Jack Y. Vanderhoek

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Dysregulated metabolic pathways in age-related macular degeneration., Meng Zhang, Nisi Jiang, Yi Chu, Olga Postnikova, Rency Varghese, Anelia Horvath, Amrita K. Cheema, and Nady Golestaneh

Submissions from 2019

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The GlySpace Alliance: towards a collaborative global glycoinformatics community., Kiyoko F. Aoki-Kinoshita, Frederique Lisacek, Raja Mazumder, William S. York, and Nicolle H. Packer

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Immunoepigenetics Combination Therapies: An Overview of the Role of HDACs in Cancer Immunotherapy., Debarati Banik, Sara Moufarrij, and Alejandro Villagra

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Prussian blue nanoparticle-based antigenicity and adjuvanticity trigger robust antitumor immune responses against neuroblastoma., Juliana Cano-Mejia, Michelle L Bookstaver, Elizabeth E Sweeney, Christopher M Jewell, and Rohan Fernandes

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HDAC11 Regulates Type I Interferon Signaling through Defatty-Acylation of SHMT2., Ji Cao, Lei Sun, Pornpun Aramsangtienchai, Nicole A Spiegelman, Xiaoyu Zhang, Weishan Huang, Edward Seto, and Hening Lin

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Stevioside inhibits experimental fibrosis by down-regulating profibrotic Smad pathways and blocking hepatic stellate cell activation., Sael Casas-Grajales, Diana Alvarez-Suarez, Erika Ramos-Tovar, Laura Dayana Buendía-Montaño, Karina Reyes-Gordillo, Javier Camacho, Víctor Tsutsumi, M Raj Lakshman, and Pablo Muriel

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Antioxidant and immunomodulatory activity induced by stevioside in liver damage: In vivo, in vitro and in silico assays., Sael Casas-Grajales, Erika Ramos-Tovar, Esmeralda Chávez-Estrada, Diana Alvarez-Suarez, Erika Hernández-Aquino, Karina Reyes-Gordillo, Carlos M Cerda-García-Rojas, Javier Camacho, Víctor Tsutsumi, M Raj Lakshman, and Pablo Muriel

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Rebaudioside A administration prevents experimental liver fibrosis: an in vivo and in vitro study of the mechanisms of action involved., Sael Casas-Grajales, Karina Reyes-Gordillo, Carlos M Cerda-García-Rojas, Víctor Tsutsumi, M Raj Lakshman, and Pablo Muriel

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Investigation of somatic single nucleotide variations in human endogenous retrovirus elements and their potential association with cancer., Ting-Chia Chang, Santosh Goud, John Torcivia-Rodriguez, Yu Hu, Qing Pan, Robel Kahsay, Jonas Blomberg, and Raja Mazumder

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CRISPR Screening "Big Data" Informs Novel Therapeutic Solutions., Sitong Chen, Lin Yang, and Wei Li

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Substance P receptor blocker, aprepitant, inhibited cutaneous and other neurogenic inflammation side effects of the EGFR1-TKI, erlotinib., Joanna J. Chmielinska, Jay H. Kramer, I-Tong Mak, Christopher F. Spurney, and William B. Weglicki

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A Reappraisal of Thymosin Alpha1 in Cancer Therapy., Claudio Costantini, Marina M. Bellet, Marilena Pariano, Giorgia Renga, Claudia Stincardini, Allan L. Goldstein, Enrico Garaci, and Luigina Romani

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Engineering a Novel 3D Printed Vascularized Tissue Model for Investigating Breast Cancer Metastasis to Bone., Haitao Cui, Timothy Esworthy, Xuan Zhou, Sung Yun Hann, Robert I. Glazer, Rong Li, and Lijie Grace Zhang

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RNA m6A methyltransferase METTL3 regulates invasiveness of melanoma cells by matrix metallopeptidase 2., Ujwal Dahal, Le Kang, and Mamta Gupta

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17-hydroxy wortmannin restores TRAIL's response by ameliorating increased beclin 1 level and autophagy function in TRAIL-resistant colon cancer cells., Sheng Dai, Shu Yang, Xin Hu, Wei Sun, Gregory Tawa, Wenge Zhu, Aaron D Schimmer, Chao He, Bingliang Fang, Hongbo Zhu, and Wei Zheng

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Mg-supplementation attenuated lipogenic and oxidative/nitrosative gene expression caused by Combination Antiretroviral Therapy (cART) in HIV-1-transgenic rats., Lama ElZohary, William B Weglicki, Joanna J Chmielinska, Jay H Kramer, and I Tong Mak

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Mg-supplementation attenuated lipogenic and oxidative/nitrosative gene expression caused by Combination Antiretroviral Therapy (cART) in HIV-1-transgenic rats., Lama ElZohary, William B Weglicki, Joanna J. Chmielinska, Jay H Kramer, and I Tong Mak

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HDAC8 regulates a stress response pathway in melanoma to mediate escape from BRAF inhibitor therapy., Michael F Emmons, Fernanda Faião-Flores, Ritin Sharma, Ram Thapa, Jane L Messina, Jurgen C Becker, Dirk Schadendorf, Edward Seto, Vernon K Sondak, John M Koomen, Yian Ann Chen, Eric K Lau, Lixin Wan, Jonathan D Licht, and Keiran S M Smalley

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History of the Discovery of Hepatitis A Virus., Stephen M Feinstone

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Chronic administration of diethylnitrosamine to induce hepatocarcinogenesis and to evaluate its synergistic effect with other hepatotoxins in mice., Sergio Fuentes-Hernández, Brisa Rodope Alarcón-Sánchez, Dafne Guerrero-Escalera, Alexia Viridiana Montes-Aparicio, María Paulette Castro-Gil, Osiris Germán Idelfonso-García, Sandra Rosas-Madrigal, Diana Ivette Aparicio-Bautista, José Luis Pérez-Hernández, Karina Reyes-Gordillo, M Raj Lakshman, Verónica Rocío Vásquez-Garzón, Rafael Baltiérrez-Hoyos, Ma de Lourdes López-González, Adolfo Sierra-Santoyo, Saúl Villa-Treviño, Julio Isael Pérez-Carreón, and Jaime Arellanes-Robledo

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Functional Analysis of HDACs in Tumorigenesis., Melissa Hadley, Satish Noonepalle, Debarati Banik, and Alejandro Villagra

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Insights into the HIV Latency and the Role of Cytokines., Joseph Hokello, Adhikarimayum Lakhikumar Sharma, Manjari Dimri, and Mudit Tyagi

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RIP sequencing in mantle cell lymphoma identifies functional long non-coding RNAs associated with translation machinery., Guangzhen Hu, Yuji Zhang, and Mamta Gupta

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Sirtuin 6 Attenuates Kaposi's Sarcoma-Associated Herpesvirus Reactivation by Suppressing Ori-Lyt Activity and Expression of RTA., Min Hu, Najealicka Armstrong, Edward Seto, Wenwei Li, Fanxiu Zhu, Paul C Wang, and Qiyi Tang

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ASD Phenotype-Genotype Associations in Concordant and Discordant Monozygotic and Dizygotic Twins Stratified by Severity of Autistic Traits., Valerie W. Hu, Christine A. Devlin, and Jessica J. Debski

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Heart Protection by Herb Formula BanXia BaiZhu TianMa Decoction in Spontaneously Hypertensive Rats., Jiaye Jiang, Dan Huang, Yuan Li, Zhongyuan Gan, Hanqing Li, Xindan Li, Ka Bian, and Yan Ke

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Flotillins in the Intercalated Disc are Potential Modulators of Cardiac Excitability., Elise L Kessler, Leonie van Stuijvenberg, Joanne J A van Bavel, Joëlle van Bennekom, Anne Zwartsen, Mathilde R Rivaud, Aryan Vink, Igor R Efimov, Alex V Postma, J Peter van Tintelen, Carol A Remme, Marc A Vos, Antje Banning, Teun P de Boer, Ritva Tikkanen, and Toon A B van Veen

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miCloud: A Plug-n-Play, Extensible, On-Premises Bioinformatics Cloud for Seamless Execution of Complex Next-Generation Sequencing Data Analysis Pipelines., Baekdoo Kim, Thahmina Ali, Changsu Dong, Carlos Lijeron, Raja Mazumder, Claudia Wultsch, and Konstantinos Krampis

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Baseline human gut microbiota profile in healthy people and standard reporting template., Charles H. King, Hiral Desai, Allison C. Sylvetsky, Jonathan LoTempio, Shant Ayanyan, Jill Carrie, Keith A Crandall, Brian C Fochtman, Lusine Gasparyan, Naila Gulzar, Paul Howell, Najy Issa, Konstantinos Krampis, Lopa Mishra, Hiroki Morizono, Joseph R Pisegna, Shuyun Rao, Yao Ren, Vahan Simonyan, Krista Smith, Sharanjit VedBrat, Michael D Yao, and Raja Mazumder

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Baseline human gut microbiota profile in healthy people and standard reporting template., Charles H. King, Hiral Desai, Allison C. Sylvetsky, Jonathan LoTempio, Shant Ayanyan, Jill Carrie, Keith A. Crandall, Brian C. Fochtman, Lusine Gasparyan, Naila Gulzar, Paul Howell, Najy Issa, Konstantinos Krampis, Lopa Mishra, Hiroki Morizono, Joseph R Pisegna, Shuyun Rao, Yao Ren, Vahan Simonyan, Krista Smith, Sharanjit VedBrat, Michael D Yao, and Raja Mazumder

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Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells., Tessa Knox, Eva Sahakian, Debarati Banik, Melissa Hadley, Erica Palmer, Satish Noonepalle, Jennifer Kim, John Powers, Maria Gracia-Hernandez, Vasco Oliveira, Fengdong Cheng, Jie Chen, Cyril Barinka, Javier Pinilla-Ibarz, Norman H Lee, Alan Kozikowski, and Alejandro Villagra

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Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells., Tessa Knox, Eva Sahakian, Debarati Banik, Melissa Hadley, Erica Palmer, Satish Noonepalle, Jennifer Kim, John Powers, Maria Gracia-Hernandez, Vasco Oliveira, Fengdong Cheng, Jie Chen, Cyril Barinka, Javier Pinilla-Ibarz, Norman H Lee, Alan Kozikowski, and Alejandro Villagra

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Nonhomologous end joining key factor XLF enhances both 5-florouracil and oxaliplatin resistance in colorectal cancer., Zhuo Liu, Miao Yu, Bingyuan Fei, Jing Sun, and Dongxin Wang

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ERK Regulates HIF1α-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer., Zhuqing Li, Wei Zhou, Yi Zhang, Wei Sun, Mingo M H Yung, Jing Sun, Jing Li, Chi-Wei Chen, Zongzhu Li, Yunxiao Meng, Jie Chai, Yuan Zhou, Stephanie S Liu, Annie N Y Cheung, Hextan Y S Ngan, David W Chan, Wei Zheng, and Wenge Zhu

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ERK regulates HIF-1α-mediated platinum resistance by directly targeting PHD2 in ovarian cancer., Zhuqing Li, Wei Zhou, Yi Zhang, Wei Sun, Mingo Mh Yung, Jing Sun, Jing Li, Chi-Wei Chen, Zongzhu Li, Yunxiao Meng, Jie Chai, Yuan Zhou, Stephanie Si Liu, Annie Nga-Yin Cheung, Hextan Yuen-Sheung Ngan, David Wai Chan, Wei Zheng, and Wenge Zhu

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The deubiquitylating enzyme USP15 regulates homologous recombination repair and cancer cell response to PARP inhibitors., Yihan Peng, Qingchao Liao, Wei Tan, Changmin Peng, Zhaohua Hu, Yali Chen, Zhuqing Li, Jing Li, Bei Zhen, Wenge Zhu, Xiangpan Li, Yi Yao, Qibin Song, Chengsheng Liu, Xiangdong Qi, Fuchu He, and Huadong Pei

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Phenotypic Subgrouping and Multi-Omics Analyses Reveal Reduced Diazepam-Binding Inhibitor (DBI) Protein Levels in Autism Spectrum Disorder with Severe Language Impairment., Chatravee Pichitpunpong, Surangrat Thongkorn, Songphon Kanlayaprasit, Wasana Yuwattana, Waluga Plaingam, Siriporn Sangsuthum, Wan Mohd Aizat, Syarul Nataqain Baharum, Tewin Tencomnao, Valerie Wailin Hu, and Tewarit Sarachana

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Emerging roles of histone modifications and HDACs in RNA splicing., Raneen Rahhal and Edward Seto

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Thymosin β4 promotes autophagy and repair via HIF-1α stabilization in chronic granulomatous disease., Giorgia Renga, Vasilis Oikonomou, Silvia Moretti, Claudia Stincardini, Marina M Bellet, Marilena Pariano, Andrea Bartoli, Stefano Brancorsini, Paolo Mosci, Andrea Finocchi, Paolo Rossi, Claudio Costantini, Enrico Garaci, Allan L Goldstein, and Luigina Romani

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Akt1 and Akt2 Isoforms Play Distinct Roles in Regulating the Development of Inflammation and Fibrosis Associated with Alcoholic Liver Disease., Karina Reyes-Gordillo, Ruchi Shah, Jaime Arellanes-Robledo, Ying Cheng, Joseph Ibrahim, and Pamela L Tuma

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HDAC8 affects MGMT levels in glioblastoma cell lines, Irene Santos-Barriopedro, Yixuan Li, Sonali Bahl, and Edward Seto

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HDAC8 affects MGMT levels in glioblastoma cell lines, Irene Santos-Barriopedro, Yixuan Li, Sonali Bahl, and Edward Seto

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Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models., Sida Shen, Melissa Hadley, Kseniya Ustinova, Jiri Pavlicek, Tessa Knox, Satish Noonepalle, Mauricio T. Tavares, Chad A. Zimprich, Guiping Zhang, Matthew B. Robers, Cyril Bařinka, Alan P. Kozikowski, and Alejandro Villagra

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The Nuclear Export and Ubiquitin-Proteasome-Dependent Degradation of PPARγ Induced By Angiotensin II., Li Sun and Ka Bian

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Sex Differences in the Effects of Prenatal Bisphenol A Exposure on Genes Associated with Autism Spectrum Disorder in the Hippocampus., Surangrat Thongkorn, Songphon Kanlayaprasit, Depicha Jindatip, Tewin Tencomnao, Valerie W Hu, and Tewarit Sarachana

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PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy., Xinyi Tu, Bo Qin, Yong Zhang, Cheng Zhang, Mohamed Kahila, Somaira Nowsheen, Ping Yin, Jian Yuan, Huadong Pei, Hu Li, Jia Yu, Zhiwang Song, Qin Zhou, Fei Zhao, Jiaqi Liu, Chao Zhang, Haidong Dong, Robert W Mutter, and Zhenkun Lou

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Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment., Rocio G Urdinguio, Virginia Lopez, Gustavo F Bayón, Rafael Diaz de la Guardia, Marta I Sierra, Estela García-Toraño, Raúl F Perez, María G García, Antonella Carella, Patricia C Pruneda, Cristina Prieto, Marija Dmitrijeva, Pablo Santamarina, Thalía Belmonte, Cristina Mangas, Elena Diaconu, Cecilia Ferrero, Juan Ramón Tejedor, Juan Luis Fernandez-Morera, Cristina Bravo, Clara Bueno, Alejandra Sanjuan-Pla, Ramon M Rodriguez, Beatriz Suarez-Alvarez, Carlos López-Larrea, Teresa Bernal, Enrique Colado, Milagros Balbín, Olivia García-Suarez, María Dolores Chiara, Inés Sáenz-de-Santa-María, Francisco Rodríguez, Ana Pando-Sandoval, Luis Rodrigo, Laura Santos, Ana Salas, Jesús Vallejo-Díaz, Ana C Carrera, Daniel Rico, Inmaculada Hernández-López, Amparo Vayá, José M Ricart, Edward Seto, Núria Sima-Teruel, Alejandro Vaquero, Luis Valledor, Maria Jesus Cañal, David Pisano, Osvaldo Graña-Castro, Tim Thomas, Anne K Voss, Pablo Menéndez, Ana Villar-Garea, Rainer Deutzmann, Agustín F Fernandez, and Mario F Fraga

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Soluble ICAM 1 and VCAM 1 Blood Levels Alert on Subclinical Atherosclerosis in Non Smokers with Asymptomatic Metabolic Syndrome, Jose F. Varona, Roberto Ortiz-Regalón, Isabel Sánchez-Vera, Beatriz López-Melgar, Cira García-Durango, José María Castellano Vázquez, Jorge M. Solis, Leticia Fernández-Friera, and Fernando Vidal-Vanaclocha

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MiR-30a regulates cancer cell response to chemotherapy through SNAI1/IRS1/AKT pathway., Tingting Wang, Gang Chen, Xuemei Ma, Yao Yang, Yali Chen, Yihan Peng, Zhigang Bai, Zhongtao Zhang, Huadong Pei, and Wei Guo

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An efficient prototype method to identify and correct misspellings in clinical text., T Elizabeth Workman, Yijun Shao, Guy Divita, and Qing Zeng-Treitler

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Identification of the PTEN-ARID4B-PI3K pathway reveals the dependency on ARID4B by PTEN-deficient prostate cancer, Ray-Chang Wu, In-Chi Young, Yu-Fang Chen, Sung-Ting Chuang, Antoun Toubaji, and Mei-Yi Wu

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Metastasis suppressor NME1 promotes non-homologous end joining of DNA double-strand breaks., Renyu Xue, Yihan Peng, Baolin Han, Xiangpan Li, Yali Chen, and Huadong Pei

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BRCA1 mutations attenuate super-enhancer function and chromatin looping in haploinsufficient human breast epithelial cells., Xiaowen Zhang, Yao Wang, Huai-Chin Chiang, Yuan-Pang Hsieh, Chang Lu, Ben Ho Park, Ismail Jatoi, Victor X Jin, Yanfen Hu, and Rong Li

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Secretome profiling identifies neuron-derived neurotrophic factor as a tumor-suppressive factor in lung cancer., Ya Zhang, Xuefeng Wu, Yan Kai, Chia-Han Lee, Fengdong Cheng, Yixuan Li, Yongbao Zhuang, Javid Ghaemmaghami, Kun-Han Chuang, Zhuo Liu, Yunxiao Meng, Meghana Keswani, Nancy R. Gough, Xiaojun Wu, Wenge Zhu, Alexandros Tzatsos, Weiqun Peng, Edward Seto, Eduardo M. Sotomayor, and Xiaoyan Zheng

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The Cdk2-c-Myc-miR-571 Axis Regulates DNA Replication and Genomic Stability by Targeting Geminin., Yi Zhang, Zhuqing Li, Qiang Hao, Wei Tan, Jing Sun, Jing Li, Chi-Wei Chen, Zongzhu Li, Yunxiao Meng, Yuan Zhou, Zhiyong Han, Huadong Pei, Melvin L DePamphilis, and Wenge Zhu

Submissions from 2018

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Ethanol targets nucleoredoxin/dishevelled interactions and stimulates phosphatidylinositol 4-phosphate production in vivo and in vitro., Jaime Arellanes-Robledo, Karina Reyes-Gordillo, Joseph Ibrahim, Leslie Leckey, Ruchi Shah, and M Raj Lakshman

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HDAC11 suppresses the thermogenic program of adipose tissue via BRD2., Rushita A. Bagchi, Bradley S. Ferguson, Matthew S. Stratton, Tianjing Hu, Maria A. Cavasin, Lei Sun, Ying-Hsi Lin, Dianxin Liu, Pilar Londono, Kunhua Song, Maria F. Pino, Lauren M. Sparks, Steven R. Smith, Philipp E. Scherer, Sheila Collins, Edward Seto, and Timothy A. McKinsey

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Challenges and Opportunities in Social Epigenomics and Cancer., Krishna Banaudha, Vineet Kumar, and Mukesh Verma

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Stevioside Inhibits Experimental Fibrosis by Downregulating Profibrotic Smad Pathways and Blocking HSC Activation., Sael Casas-Grajales, Diana Alvarez-Suarez, Erika Ramos-Tovar, Laura Dayana Buendía-Montaño, Karina Reyes-Gordillo, Javier Camacho, Víctor Tsutsumi, M Raj Lakshman, and Pablo Muriel

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DHS (trans-4,4'-dihydroxystilbene) Suppresses DNA Replication and Tumor Growth by Inhibiting RRM2 (ribonucleotide Reductase Regulatory Subunit M2)., Chi-Wei Chen, Yongming Li, Shuya Hu, Wei Zhou, Yunxiao Meng, Zongzhu Li, Yi Zhang, Jing Sun, Zhou Bo, Melvin L DePamphilis, Yun Yen, Zhiyong Han, and Wenge Zhu

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Gene-Specific Genetic Complementation between Brca1 and Cobra1 During Mouse Mammary Gland Development., Huai-Chin Chiang, Xiaowen Zhang, Xiayan Zhao, Chi Zhang, Jerry Chen, Paula Garza, Sabrina Smith, Thomas Ludwig, Richard J Baer, Rong Li, and Yanfen Hu

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Loss and gain of N-linked glycosylation sequons due to single-nucleotide variation in cancer., Yu Fan, Yu Hu, Cheng Yan, Radoslav Goldman, Yang Pan, Raja Mazumder, and Hayley M Dingerdissen

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Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein BMI1 in breast cancer cells., Joseph E Gergely, Armond E Dorsey, Goberdhan P Dimri, and Manjari Dimri

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DEXTER: Disease-Expression Relation Extraction from Text., Samir Gupta, Hayley Dingerdissen, Karen E Ross, Yu Hu, Cathy H Wu, Raja Mazumder, and K Vijay-Shanker

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Prognostic and Therapeutic Significance of Phosphorylated STAT3 and Protein Tyrosine Phosphatase-6 in Peripheral-T Cell Lymphoma., Jing Jing Han, Megan O'byrne, Mary J Stenson, Matthew J Maurer, Linda E Wellik, Andrew L Feldman, Ellen D McPhail, Thomas E Witzig, and Mamta Gupta

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Elevated GLI3 expression in germinal center diffuse large B cell lymphoma., Weiguo Han, Gabriela Ibarra, Mamta Gupta, Yanbin Yin, and Sherine F Elsawa

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The Comparative Associations of Ultrasound and Computed Tomography Estimates of Muscle Quality with Physical Performance and Metabolic Parameters in Older Men., Michael O Harris-Love, Nilo A Avila, Bernadette Adams, June Zhou, Bryant Seamon, Catheeja Ismail, Syed H Zaidi, Courtney A Kassner, Frank Liu, and Marc R Blackman

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MicroRNA-34 family in breast cancer: from research to therapeutic potential., Saber Imani, Ray-Chang Wu, and Junjiang Fu

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Total Flavonoids from Radix Glycyrrhiza Exert Anti-Inflammatory and Antitumorigenic Effects by Inactivating iNOS Signaling Pathways., Yi-Xin Jiang, Yang-Yi Dai, Yi-Feng Pan, Xi-Min Wu, Yue Yang, Ka Bian, and Dan-Dan Zhang

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RGN-259 (thymosin β4) improves clinically important dry eye efficacies in comparison with prescription drugs in a dry eye model., Chae Eun Kim, Hynda K Kleinman, Gabriel Sosne, George W Ousler, Kyeongsoon Kim, Sinwook Kang, and Jaewook Yang

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Evolution of echovirus 11 in a chronically infected immunodeficient patient., Majid Laassri, Tatiana Zagorodnyaya, Sharon Hassin-Baer, Rachel Handsher, Danit Sofer, Merav Weil, Konstantinos Karagiannis, Vahan Simonyan, Konstantin Chumakov, and Lester Shulman

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Evolution of echovirus 11 in a chronically infected immunodeficient patient., Majid Laassri, Tatiana Zagorodnyaya, Sharon Hassin-Baer, Rachel Handsher, Danit Sofer, Merav Weil, Konstantinos Karagiannis, Vahan Simonyan, Konstantin Chumakov, and Lester Shulman

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Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication., Hongbo Ling, Lirong Peng, Jianbo Wang, Raneen Rahhal, and Edward Seto

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Silencing of HDAC6 as a therapeutic target in chronic lymphocytic leukemia., Kamira Maharaj, John J Powers, Alex Achille, Susan Deng, Renee Fonseca, Mibel Pabon-Saldana, Steven N Quayle, Simon S Jones, Alejandro Villagra, Eduardo M Sotomayor, Eva Sahakian, and Javier Pinilla-Ibarz

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Combination ART-Induced Oxidative/Nitrosative Stress, Neurogenic Inflammation and Cardiac Dysfunction in HIV-1 Transgenic (Tg) Rats: Protection by Mg., I Tong Mak, Joanna J Chmielinska, Christopher F Spurney, William B Weglicki, and Jay H Kramer

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DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer., Yunxiao Meng, Chi-Wei Chen, Mingo M H Yung, Wei Sun, Jing Sun, Zhuqing Li, Jing Li, Zongzhu Li, Wei Zhou, Stephanie S Liu, Annie N Y Cheung, Hextan Y S Ngan, John C Braisted, Yan Kai, Weiqun Peng, Alexandros Tzatsos, Yiliang Li, Zhijun Dai, Wei Zheng, David W Chan, and Wenge Zhu

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Are endocrine disrupting compounds environmental risk factors for autism spectrum disorder?, Amer Moosa, Henry Shu, Tewarit Sarachana, and Valerie W Hu

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CBX7 regulates stem cell-like properties of gastric cancer cells via p16 and AKT-NF-κB-miR-21 pathways., Su-Jie Ni, Li-Qin Zhao, Xiao-Feng Wang, Zhen-Hua Wu, Rui-Xi Hua, Chun-Hua Wan, Jie-Yun Zhang, Xiao-Wei Zhang, Ming-Zhu Huang, Lu Gan, Hua-Lin Sun, Goberdhan P Dimri, and Wei-Jian Guo

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Phase I trial of histone deacetylase inhibitor panobinostat in addition to glucocorticoids for primary therapy of acute graft-versus-host disease., Lia Perez, Hugo Fernandez, Pedro Horna, Marcie Riches, Frederick Locke, Teresa Field, John Powers, Eva Sahakian, Alejandro Villagra, Asmita Mishra, Brian Betts, Mohamed Kharfan-Dabaja, Francisca Beato, Leonel Ochoa-Bayona, Joseph Pidala, and Claudio Anasetti

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Thymosin β4 Limits Inflammation through Autophagy., Giorgia Renga, Vasilis Oikonomou, Claudia Stincardini, Marilena Pariano, Monica Borghi, Claudio Costantini, Andrea Bartoli, Enrico Garaci, Allan L Goldstein, and Luigina Romani

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Reply to 'F508del-CFTR is not corrected by thymosin α1'., Luigina Romani, Claudia Stincardini, Stefano Giovagnoli, Maurizio Paci, Valeria R Villella, Luigi Sforna, Giorgia Renga, Marina M Bellet, Claudio Costantini, Paolo Puccetti, Guido Kroemer, Luigi Maiuri, Mauro Pessia, Allan Goldstein, and Enrico Garaci

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Integrated genome-wide Alu methylation and transcriptome profiling analyses reveal novel epigenetic regulatory networks associated with autism spectrum disorder., Thanit Saeliw, Chayanin Tangsuwansri, Surangrat Thongkorn, Weerasak Chonchaiya, Kanya Suphapeetiporn, Apiwat Mutirangura, Tewin Tencomnao, Valerie W Hu, and Tewarit Sarachana

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Thymosin β4 Prevents Oxidative Stress, Inflammation, and Fibrosis in Ethanol- and LPS-Induced Liver Injury in Mice, Ruchi Shah, Karina Reyes-Gordillo, Ying Cheng, Ravi Varatharajalu, Joseph Ibrahim, and M Raj Lakshman

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Thymosin β4 inhibits PDGF-BB induced activation, proliferation, and migration of human hepatic stellate cells via its actin-binding domain., Ruchi Shah, Karina Reyes-Gordillo, and Marcos Rojkind

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Annexin A2 (ANX A2): An Emerging Biomarker and Potential Therapeutic Target for Aggressive Cancers., Mahesh C Sharma

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miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer., Jing Sun, Xin Cai, Mingo Mh Yung, Wei Zhou, Jing Li, Yi Zhang, Zhuqing Li, Stephanie S Liu, Annie N Y Cheung, Hextan Y S Ngan, Yiliang Li, Zhijun Dai, Yan Kai, Alexandros Tzatsos, Weiqun Peng, David W Chan, and Wenge Zhu

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Programming and Regulation of Metabolic Homeostasis by HDAC11., Lei Sun, Caralina Marin de Evsikova, Ka Bian, Alexandra Achille, Elphine Telles, Huadong Pei, and Edward Seto

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Loss of HDAC11 Ameliorates Clinical Symptoms in a Multiple Sclerosis Mouse Model., Lei Sun, Elphine Telles, Molly Karl, Fengdong Cheng, Noreen Luetteke, Eduardo M Sotomayor, Robert H Miller, and Edward Seto

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Tumor-extrinsic discoidin domain receptor 1 promotes mammary tumor growth by regulating adipose stromal interleukin 6 production in mice., Xiujie Sun, Kshama Gupta, Bogang Wu, Deyi Zhang, Bin Yuan, Xiaowen Zhang, Huai-Chin Chiang, Chi Zhang, Tyler J Curiel, Michelle P Bendeck, Stephen Hursting, Yanfen Hu, and Rong Li

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Investigation of epigenetic regulatory networks associated with autism spectrum disorder (ASD) by integrated global LINE-1 methylation and gene expression profiling analyses., Chayanin Tangsuwansri, Thanit Saeliw, Surangrat Thongkorn, Weerasak Chonchaiya, Kanya Suphapeetiporn, Apiwat Mutirangura, Tewin Tencomnao, Valerie Wailin Hu, and Tewarit Sarachana

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The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA., Dharendra Thapa, Kaiyuan Wu, Michael W Stoner, Bingxian Xie, Manling Zhang, Janet R Manning, Zhongping Lu, Jian H Li, Yong Chen, Marjan Gucek, Martin P Playford, Nehal N Mehta, Daniel Harmon, Robert M O'Doherty, Michael J Jurczak, Michael N Sack, and Iain Scott

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The Impact of lncRNA Dysregulation on Clinicopathology and Survival of Breast Cancer: A Systematic Review and Meta-analysis, Tian Tian, Meng Wang, Shuai Lin, Zhiming Dan, Kang Liu, Wenge Zhu, and +several additional authors

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Expression, Clinical Significance, and Functional Prediction of MNX1 in Breast Cancer., Tian Tian, Meng Wang, Yuyao Zhu, Wenge Zhu, Tielin Yang, Hongtao Li, Shuai Lin, Cong Dai, Yujiao Deng, Dingli Song, Na Li, Zhen Zhai, and Zhi-Jun Dai

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A Primer for Access to Repositories of Cancer-Related Genomic Big Data., John Torcivia-Rodriguez, Hayley Dingerdissen, Ting-Chia Chang, and Raja Mazumder

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Hospital Care for Jews in Nineteenth-century Amsterdam: The Emergence of the First Jewish Hospitals, Jack Y. Vanderhoek