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Submissions from 2020

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Nucleoredoxin interaction with flightless-I/actin complex is differentially altered in alcoholic liver disease., Brisa Rodope Alarcón-Sánchez, Dafne Guerrero-Escalera, Sandra Rosas-Madrigal, Diana Ivette Aparicio-Bautista, Karina Reyes-Gordillo, M Raj Lakshman, Arturo Ortiz-Fernández, Héctor Quezada, Óscar Medina-Contreras, Saúl Villa-Treviño, Julio Isael Pérez-Carreón, and Jaime Arellanes-Robledo

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Regulation of histone deacetylase activities and functions by phosphorylation and its physiological relevance., Sonali Bahl and Edward Seto

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CpG-coated Prussian blue nanoparticles-based photothermal therapy combined with anti-CTLA-4 immune checkpoint blockade triggers a robust abscopal effect against neuroblastoma., Juliana Cano-Mejia, Anshi Shukla, Debbie K. Ledezma, Erica Palmer, Alejandro Villagra, and Rohan Fernandes

Development of an Integrated Platform Using Multidisciplinary Real-World Data to Facilitate Biomarker Discovery for Medical Products, Stefan Dabic, Yasameen Azarbaijani, Tigran Karapetyan, Nilsa Loyo-Berrios, Vahan Simonyan, Terrie Kitchner, Murray Brilliant, and Yelizaveta Torosyan

Development of an Integrated Platform Using Multidisciplinary Real-World Data to Facilitate Biomarker Discovery for Medical Products, Stefan Dabic, Yasameen Azarbaijani, Tigran Karapetyan, Nilsa Loyo-Berrios, Vahan Simonyan, Terrie Kitchner, Murray Brilliant, and Yelizaveta Torosyan

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Regulation of poly(a)-specific ribonuclease activity by reversible lysine acetylation., Eden A. Dejene, Yixuan Li, Zahra Showkatian, Hongbo Ling, and Edward Seto

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Regulation of poly(a)-specific ribonuclease activity by reversible lysine acetylation., Eden A. Dejene, Yixuan Li, Zahra Showkatian, Hongbo Ling, and Edward Seto

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OncoMX: A Knowledgebase for Exploring Cancer Biomarkers in the Context of Related Cancer and Healthy Data., Hayley M. Dingerdissen, Frederic Bastian, K Vijay-Shanker, Marc Robinson-Rechavi, Amanda Bell, Nikhita Gogate, Samir Gupta, Evan Holmes, Robel Kahsay, Jonathon Keeney, Heather Kincaid, Charles Hadley King, David Liu, Daniel J. Crichton, and Raja Mazumder

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Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection., Cortney E Heim, Megan E Bosch, Kelsey J Yamada, Amy L Aldrich, Sujata S Chaudhari, David Klinkebiel, Casey M Gries, Abdulelah A Alqarzaee, Yixuan Li, Vinai C Thomas, Edward Seto, Adam R Karpf, and Tammy Kielian

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Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection., Cortney E Heim, Megan E Bosch, Kelsey J Yamada, Amy L Aldrich, Sujata S Chaudhari, David Klinkebiel, Casey M Gries, Abdulelah A Alqarzaee, Yixuan Li, Vinai C Thomas, Edward Seto, Adam R Karpf, and Tammy Kielian

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Ubiquitin-Conjugating Enzyme 2S Enhances Viral Replication by Inhibiting Type I IFN Production through Recruiting USP15 to Deubiquitinate TBK1., Li Huang, Hongyang Liu, Kunli Zhang, Qingwen Meng, Liang Hu, Yuanfeng Zhang, Zhida Xiang, Jiangnan Li, Yuying Yang, Yali Chen, Shangjin Cui, Hong Tang, Huadong Pei, Zhigao Bu, and Changjiang Weng

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BGL3 lncRNA mediates retention of the BRCA1/BARD1 complex at DNA damage sites., Zhaohua Hu, Shaojie Mi, Ting Zhao, Changmin Peng, Yihan Peng, Lulu Chen, Wenge Zhu, Yi Yao, Qibin Song, Xiangpan Li, Xinzhi Li, Chenxi Jia, and Huadong Pei

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GlyGen data model and processing workflow., Robel Kahsay, Jeet Vora, Rahi Navelkar, Reza Mousavi, Brian C. Fochtman, Xavier Holmes, Nagarajan Pattabiraman, Rene Ranzinger, Rupali Mahadik, Tatiana Williamson, Sujeet Kulkarni, Gaurav Agarwal, Maria Martin, Preethi Vasudev, Leyla Garcia, Nathan Edwards, Wenjin Zhang, Darren A Natale, Karen Ross, Kiyoko F Aoki-Kinoshita, Matthew P Campbell, William S York, and Raja Mazumder

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Recent Advances in Systems and Network Medicine: Meeting Report from the First International Conference in Systems and Network Medicine., Emma Kurnat-Thoma, Ancha Baranova, Pat Baird, Elia Brodsky, Atul J. Butte, Amrita K. Cheema, Feixiong Cheng, Shuchismita Dutta, Christina Grant, James Giordano, Anke H. Maitland-van der Zee, Douglas B. Fridsma, Robert Jarrin, Maricel G. Kann, Jonathon Keeney, Joseph Loscalzo, Guru Madhavan, Bradley A. Maron, Dennis K. McBride, Maeve McKean, Seong K. Mun, James C. Palmer, Bakul Patel, Kapil Parakh, Anne R. Pariser, Christian Pristipino, Timothy R D J Radstake, Harsha K. Rajasimha, William B. Rouse, Damjana Rozman, Alif Saleh, Harald H H W Schmidt, Nikolaus Schultz, Tavpritesh Sethi, Edwin K. Silverman, Jessica Skopac, Igor Svab, Sylvia Trujillo, James E. Valentine, Dinesh Verma, Bruce J. West, and Sona Vasudevan

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HDAC10 Regulates Cancer Stem-Like Cell Properties in KRAS-Driven Lung Adenocarcinoma., Yixuan Li, Xiangyang Zhang, Shaoqi Zhu, Eden A. Dejene, Weiqun Peng, Antonia Sepulveda, and Edward Seto

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Transcriptional dysregulation in developing trigeminal sensory neurons in the LgDel mouse model of DiGeorge 22q11.2 Deletion Syndrome., Thomas M. Maynard, Anelia Horvath, James Bernout, Beverly A. Karpinski, Andre L P Tavares, Ankita Shah, Qianqian Zheng, Liam Spurr, Jacqueline Olender, Sally A. Moody, Claire M. Fraser, Anthony-S LaMantia, and Norman H. Lee

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Combining DNMT and HDAC6 inhibitors increases anti-tumor immune signaling and decreases tumor burden in ovarian cancer., Sara Moufarrij, Aneil Srivastava, Stephanie Gomez, Melissa Hadley, Erica Palmer, Paul Tran Austin, Sarah Chisholm, Kyle Roche, Angela Yu, Jing Li, Wenge Zhu, Micael Lopez-Acevedo, Alejandro Villagra, and Katherine B. Chiappinelli

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Estimating the Allele-Specific Expression of SNVs From 10× Genomics Single-Cell RNA-Sequencing Data., Prashant N. M, Hongyu Liu, Pavlos Bousounis, Liam Spurr, Nawaf Alomran, Helen Ibeawuchi, Justin Sein, Dacian Reece-Stremtan, and Anelia Horvath

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Testing the "Grandma Hypothesis": Characterizing Skin Microbiome Diversity as a Project-Based Learning Approach to Genomics., Marcos Pérez-Losada, Kelly M Crandall, and Keith A. Crandall

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Thymosin α1 protects from CTLA-4 intestinal immunopathology., Giorgia Renga, Marina M Bellet, Marilena Pariano, Marco Gargaro, Claudia Stincardini, Fiorella D'Onofrio, Paolo Mosci, Stefano Brancorsini, Andrea Bartoli, Allan L. Goldstein, Enrico Garaci, Luigina Romani, and Claudio Costantini

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Prenatal exposure to bisphenol A alters the transcriptome-interactome profiles of genes associated with Alzheimer's disease in the offspring hippocampus., Suporn Sukjamnong, Surangrat Thongkorn, Songphon Kanlayaprasit, Thanit Saeliw, Kanlayaphat Hussem, Watis Warayanon, Valerie W. Hu, Tewin Tencomnao, and Tewarit Sarachana

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Scanning window analysis of non-coding regions within normal-tumor whole-genome sequence samples., John Torcivia and Raja Mazumder

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A Tale of Two Nineteenth-century Dutch Jewish Hospitals-One a Success, The Other a Failure., Jack Y. Vanderhoek

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Liver prometastatic reaction: Stimulating factors and responsive cancer phenotypes., Fernando Vidal-Vanaclocha, Olatz Crende, Cira García de Durango, Alejandro Herreros-Pomares, Sandra López-Doménech, Álvaro González, Eva Ruiz-Casares, Thierry Vilboux, Riccardo Caruso, Hipólito Durán, Antonio Gil, Benedetto Ielpo, Fernando Lapuente, Yolanda Quijano, Emilio Vicente, Leticia Vidal-Lartitegui, and Eduardo M. Sotomayor

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Genetic ablation of adipocyte PD-L1 reduces tumor growth but accentuates obesity-associated inflammation., Bogang Wu, Huai-Chin Chiang, Xiujie Sun, Bin Yuan, Payal Mitra, Yanfen Hu, Tyler J Curiel, and Rong Li

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PPARγ inhibition boosts efficacy of PD-L1 Checkpoint Blockade Immunotherapy against Murine Melanoma in a sexually dimorphic manner., Bogang Wu, Xiujie Sun, Bin Yuan, Fei Ge, Harshita B Gupta, Huai-Chin Chiang, Jingwei Li, Yanfen Hu, Tyler J. Curiel, and Rong Li

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GlyGen: Computational and Informatics Resources for Glycoscience., William S York, Raja Mazumder, Rene Ranzinger, Nathan Edwards, Robel Kahsay, Kiyoko F Aoki-Kinoshita, Matthew P Campbell, Richard D Cummings, Ten Feizi, Maria Martin, Darren A Natale, Nicolle H Packer, Robert J Woods, Gaurav Agarwal, Sena Arpinar, Sanath Bhat, Judith Blake, Leyla Jael Garcia Castro, Brian Fochtman, Jeffrey Gildersleeve, Radoslav Goldman, Xavier Holmes, Vinamra Jain, Sujeet Kulkarni, Rupali Mahadik, Akul Mehta, Reza Mousavi, Sandeep Nakarakommula, Rahi Navelkar, Nagarajan Pattabiraman, Michael J Pierce, Karen Ross, Preethi Vasudev, Jeet Vora, Tatiana Williamson, and Wenjin Zhang

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Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression., Li Yu, Bin Zhang, Dinesh Deochand, Maria A Sacta, Maddalena Coppo, Yingli Shang, Ziyi Guo, Xiaomin Zeng, David A Rollins, Bowranigan Tharmalingam, Rong Li, Yurii Chinenov, Inez Rogatsky, and Xiaoyu Hu

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Dysregulated metabolic pathways in age-related macular degeneration., Meng Zhang, Nisi Jiang, Yi Chu, Olga Postnikova, Rency Varghese, Anelia Horvath, Amrita K. Cheema, and Nady Golestaneh

A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing, Wen Wei Zhang, Subir Karmakar, Sreenivas Gannavaram, Ranadhir Dey, Patrick Lypaczewski, Nevien Ismail, Abid Siddiqui, Vahan Simonyan, Fabiano Oliveira, Iliano V. Coutinho-Abreu, Thiago DeSouza-Vieira, Claudio Meneses, James Oristian, Tiago D. Serafim, Abu Musa, Risa Nakamura, Noushin Saljoughian, Greta Volpedo, Monika Satoskar, Sanika Satoskar, Pradeep K. Dagur, J. Philip McCoy, Shaden Kamhawi, Jesus G. Valenzuela, Shinjiro Hamano, Abhay R. Satoskar, Greg Matlashewski, and Hira L. Nakhasi

A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing, Wen Wei Zhang, Subir Karmakar, Sreenivas Gannavaram, Ranadhir Dey, Patrick Lypaczewski, Nevien Ismail, Abid Siddiqui, Vahan Simonyan, Fabiano Oliveira, Iliano V. Coutinho-Abreu, Thiago DeSouza-Vieira, Claudio Meneses, James Oristian, Tiago D. Serafim, Abu Musa, Risa Nakamura, Noushin Saljoughian, Greta Volpedo, Monika Satoskar, Sanika Satoskar, Pradeep K. Dagur, J. Philip McCoy, Shaden Kamhawi, Jesus G. Valenzuela, Shinjiro Hamano, Abhay R. Satoskar, Greg Matlashewski, and Hira L. Nakhasi

Submissions from 2019

Codon and Codon-Pair Usage Tables (CoCoPUTs): Facilitating Genetic Variation Analyses and Recombinant Gene Design, Aikaterini Alexaki, Jacob Kames, David D. Holcomb, John Athey, Luis V. Santana-Quintero, Phuc Vihn Nguyen Lam, Nobuko Hamasaki-Katagiri, Ekaterina Osipova, Vahan Simonyan, Haim Bar, Anton A. Komar, and Chava Kimchi-Sarfaty

Codon and Codon-Pair Usage Tables (CoCoPUTs): Facilitating Genetic Variation Analyses and Recombinant Gene Design, Aikaterini Alexaki, Jacob Kames, David D. Holcomb, John Athey, Luis V. Santana-Quintero, Phuc Vihn Nguyen Lam, Nobuko Hamasaki-Katagiri, Ekaterina Osipova, Vahan Simonyan, Haim Bar, Anton A. Komar, and Chava Kimchi-Sarfaty

Cost and healthcare utilization among non-elderly head and neck cancer patients in the military health system, a single-payer universal health care model, Art Ambrosio, Diana D. Jeffery, Laura Hopkins, and Harry B. Burke

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The GlySpace Alliance: towards a collaborative global glycoinformatics community., Kiyoko F. Aoki-Kinoshita, Frederique Lisacek, Raja Mazumder, William S. York, and Nicolle H. Packer

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Immunoepigenetics Combination Therapies: An Overview of the Role of HDACs in Cancer Immunotherapy., Debarati Banik, Sara Moufarrij, and Alejandro Villagra

Identification and quantification of defective virus genomes in high throughput sequencing data using DVG-profiler, a novel post-sequence alignment processing algorithm, Trent J. Bosma, Konstantinos Karagiannis, Luis Santana-Quintero, Natalia Ilyushina, Tatiana Zagorodnyaya, Svetlana Petrovskaya, Majid Laassri, Raymond P. Donnelly, Steven Rubin, Vahan Simonyan, and Christian J. Sauder

Identification and quantification of defective virus genomes in high throughput sequencing data using DVG-profiler, a novel post-sequence alignment processing algorithm, Trent J. Bosma, Konstantinos Karagiannis, Luis Santana-Quintero, Natalia Ilyushina, Tatiana Zagorodnyaya, Svetlana Petrovskaya, Majid Laassri, Raymond P. Donnelly, Steven Rubin, Vahan Simonyan, and Christian J. Sauder

Is the patient cured?, Harry B. Burke and Scott Kopetz

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Prussian blue nanoparticle-based antigenicity and adjuvanticity trigger robust antitumor immune responses against neuroblastoma., Juliana Cano-Mejia, Michelle L Bookstaver, Elizabeth E Sweeney, Christopher M Jewell, and Rohan Fernandes

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HDAC11 Regulates Type I Interferon Signaling through Defatty-Acylation of SHMT2., Ji Cao, Lei Sun, Pornpun Aramsangtienchai, Nicole A Spiegelman, Xiaoyu Zhang, Weishan Huang, Edward Seto, and Hening Lin

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Stevioside inhibits experimental fibrosis by down-regulating profibrotic Smad pathways and blocking hepatic stellate cell activation., Sael Casas-Grajales, Diana Alvarez-Suarez, Erika Ramos-Tovar, Laura Dayana Buendía-Montaño, Karina Reyes-Gordillo, Javier Camacho, Víctor Tsutsumi, M Raj Lakshman, and Pablo Muriel

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Antioxidant and immunomodulatory activity induced by stevioside in liver damage: In vivo, in vitro and in silico assays., Sael Casas-Grajales, Erika Ramos-Tovar, Esmeralda Chávez-Estrada, Diana Alvarez-Suarez, Erika Hernández-Aquino, Karina Reyes-Gordillo, Carlos M Cerda-García-Rojas, Javier Camacho, Víctor Tsutsumi, M Raj Lakshman, and Pablo Muriel

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Rebaudioside A administration prevents experimental liver fibrosis: an in vivo and in vitro study of the mechanisms of action involved., Sael Casas-Grajales, Karina Reyes-Gordillo, Carlos M Cerda-García-Rojas, Víctor Tsutsumi, M Raj Lakshman, and Pablo Muriel

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Investigation of somatic single nucleotide variations in human endogenous retrovirus elements and their potential association with cancer., Ting-Chia Chang, Santosh Goud, John Torcivia-Rodriguez, Yu Hu, Qing Pan, Robel Kahsay, Jonas Blomberg, and Raja Mazumder

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CRISPR Screening "Big Data" Informs Novel Therapeutic Solutions., Sitong Chen, Lin Yang, and Wei Li

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Substance P receptor blocker, aprepitant, inhibited cutaneous and other neurogenic inflammation side effects of the EGFR1-TKI, erlotinib., Joanna J. Chmielinska, Jay H. Kramer, I-Tong Mak, Christopher F. Spurney, and William B. Weglicki

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A Reappraisal of Thymosin Alpha1 in Cancer Therapy., Claudio Costantini, Marina M. Bellet, Marilena Pariano, Giorgia Renga, Claudia Stincardini, Allan L. Goldstein, Enrico Garaci, and Luigina Romani

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Engineering a Novel 3D Printed Vascularized Tissue Model for Investigating Breast Cancer Metastasis to Bone., Haitao Cui, Timothy Esworthy, Xuan Zhou, Sung Yun Hann, Robert I. Glazer, Rong Li, and Lijie Grace Zhang

Blockchain: An enabler for healthcare and life sciences transformation, F. Curbera, D. M. Dias, V. Simonyan, W. A. Yoon, and A. Casella

Blockchain: An enabler for healthcare and life sciences transformation, F. Curbera, D. M. Dias, V. Simonyan, W. A. Yoon, and A. Casella

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RNA m6A methyltransferase METTL3 regulates invasiveness of melanoma cells by matrix metallopeptidase 2., Ujwal Dahal, Le Kang, and Mamta Gupta

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17-hydroxy wortmannin restores TRAIL's response by ameliorating increased beclin 1 level and autophagy function in TRAIL-resistant colon cancer cells., Sheng Dai, Shu Yang, Xin Hu, Wei Sun, Gregory Tawa, Wenge Zhu, Aaron D Schimmer, Chao He, Bingliang Fang, Hongbo Zhu, and Wei Zheng

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Mg-supplementation attenuated lipogenic and oxidative/nitrosative gene expression caused by Combination Antiretroviral Therapy (cART) in HIV-1-transgenic rats., Lama ElZohary, William B Weglicki, Joanna J Chmielinska, Jay H Kramer, and I Tong Mak

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Mg-supplementation attenuated lipogenic and oxidative/nitrosative gene expression caused by Combination Antiretroviral Therapy (cART) in HIV-1-transgenic rats., Lama ElZohary, William B Weglicki, Joanna J. Chmielinska, Jay H Kramer, and I Tong Mak

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HDAC8 regulates a stress response pathway in melanoma to mediate escape from BRAF inhibitor therapy., Michael F Emmons, Fernanda Faião-Flores, Ritin Sharma, Ram Thapa, Jane L Messina, Jurgen C Becker, Dirk Schadendorf, Edward Seto, Vernon K Sondak, John M Koomen, Yian Ann Chen, Eric K Lau, Lixin Wan, Jonathan D Licht, and Keiran S M Smalley

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History of the Discovery of Hepatitis A Virus., Stephen M Feinstone

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Chronic administration of diethylnitrosamine to induce hepatocarcinogenesis and to evaluate its synergistic effect with other hepatotoxins in mice., Sergio Fuentes-Hernández, Brisa Rodope Alarcón-Sánchez, Dafne Guerrero-Escalera, Alexia Viridiana Montes-Aparicio, María Paulette Castro-Gil, Osiris Germán Idelfonso-García, Sandra Rosas-Madrigal, Diana Ivette Aparicio-Bautista, José Luis Pérez-Hernández, Karina Reyes-Gordillo, M Raj Lakshman, Verónica Rocío Vásquez-Garzón, Rafael Baltiérrez-Hoyos, Ma de Lourdes López-González, Adolfo Sierra-Santoyo, Saúl Villa-Treviño, Julio Isael Pérez-Carreón, and Jaime Arellanes-Robledo

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Functional Analysis of HDACs in Tumorigenesis., Melissa Hadley, Satish Noonepalle, Debarati Banik, and Alejandro Villagra

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Insights into the HIV Latency and the Role of Cytokines., Joseph Hokello, Adhikarimayum Lakhikumar Sharma, Manjari Dimri, and Mudit Tyagi

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RIP sequencing in mantle cell lymphoma identifies functional long non-coding RNAs associated with translation machinery., Guangzhen Hu, Yuji Zhang, and Mamta Gupta

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Sirtuin 6 Attenuates Kaposi's Sarcoma-Associated Herpesvirus Reactivation by Suppressing Ori-Lyt Activity and Expression of RTA., Min Hu, Najealicka Armstrong, Edward Seto, Wenwei Li, Fanxiu Zhu, Paul C Wang, and Qiyi Tang

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ASD Phenotype-Genotype Associations in Concordant and Discordant Monozygotic and Dizygotic Twins Stratified by Severity of Autistic Traits., Valerie W. Hu, Christine A. Devlin, and Jessica J. Debski

Mental health comorbidities and cost/utilization outcomes in head and neck cancer patients, Diana D. Jeffery, Lcdr Art Ambrosio, Laura Hopkins, and Harry B. Burke

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Heart Protection by Herb Formula BanXia BaiZhu TianMa Decoction in Spontaneously Hypertensive Rats., Jiaye Jiang, Dan Huang, Yuan Li, Zhongyuan Gan, Hanqing Li, Xindan Li, Ka Bian, and Yan Ke

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Flotillins in the Intercalated Disc are Potential Modulators of Cardiac Excitability., Elise L Kessler, Leonie van Stuijvenberg, Joanne J A van Bavel, Joëlle van Bennekom, Anne Zwartsen, Mathilde R Rivaud, Aryan Vink, Igor R Efimov, Alex V Postma, J Peter van Tintelen, Carol A Remme, Marc A Vos, Antje Banning, Teun P de Boer, Ritva Tikkanen, and Toon A B van Veen

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miCloud: A Plug-n-Play, Extensible, On-Premises Bioinformatics Cloud for Seamless Execution of Complex Next-Generation Sequencing Data Analysis Pipelines., Baekdoo Kim, Thahmina Ali, Changsu Dong, Carlos Lijeron, Raja Mazumder, Claudia Wultsch, and Konstantinos Krampis

Baseline human gut microbiota profile in healthy people and standard reporting template, Charles H. King, Hiral Desai, Allison C. Sylvetsky, Jonathan LoTempio, Shant Ayanyan, Jill Carrie, Keith A. Crandall, Brian C. Fochtman, Lusine Gasparyan, Naila Gulzar, Paul Howell, Najy Issa, Konstantinos Krampis, Lopa Mishra, Hiroki Morizono, Joseph R. Pisegna, Shuyun Rao, Yao Ren, Vahan Simonyan, Krista Smith, Sharanjit VedBrat, Michael D. Yao, and Raja Mazumder

Baseline human gut microbiota profile in healthy people and standard reporting template, Charles H. King, Hiral Desai, Allison C. Sylvetsky, Jonathan LoTempio, Shant Ayanyan, Jill Carrie, Keith A. Crandall, Brian C. Fochtman, Lusine Gasparyan, Naila Gulzar, Paul Howell, Najy Issa, Konstantinos Krampis, Lopa Mishra, Hiroki Morizono, Joseph R. Pisegna, Shuyun Rao, Yao Ren, Vahan Simonyan, Krista Smith, Sharanjit VedBrat, Michael D. Yao, and Raja Mazumder

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Baseline human gut microbiota profile in healthy people and standard reporting template., Charles H. King, Hiral Desai, Allison C. Sylvetsky, Jonathan LoTempio, Shant Ayanyan, Jill Carrie, Keith A Crandall, Brian C Fochtman, Lusine Gasparyan, Naila Gulzar, Paul Howell, Najy Issa, Konstantinos Krampis, Lopa Mishra, Hiroki Morizono, Joseph R Pisegna, Shuyun Rao, Yao Ren, Vahan Simonyan, Krista Smith, Sharanjit VedBrat, Michael D Yao, and Raja Mazumder

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Baseline human gut microbiota profile in healthy people and standard reporting template., Charles H. King, Hiral Desai, Allison C. Sylvetsky, Jonathan LoTempio, Shant Ayanyan, Jill Carrie, Keith A. Crandall, Brian C. Fochtman, Lusine Gasparyan, Naila Gulzar, Paul Howell, Najy Issa, Konstantinos Krampis, Lopa Mishra, Hiroki Morizono, Joseph R Pisegna, Shuyun Rao, Yao Ren, Vahan Simonyan, Krista Smith, Sharanjit VedBrat, Michael D Yao, and Raja Mazumder

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Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells., Tessa Knox, Eva Sahakian, Debarati Banik, Melissa Hadley, Erica Palmer, Satish Noonepalle, Jennifer Kim, John Powers, Maria Gracia-Hernandez, Vasco Oliveira, Fengdong Cheng, Jie Chen, Cyril Barinka, Javier Pinilla-Ibarz, Norman H Lee, Alan Kozikowski, and Alejandro Villagra

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Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells., Tessa Knox, Eva Sahakian, Debarati Banik, Melissa Hadley, Erica Palmer, Satish Noonepalle, Jennifer Kim, John Powers, Maria Gracia-Hernandez, Vasco Oliveira, Fengdong Cheng, Jie Chen, Cyril Barinka, Javier Pinilla-Ibarz, Norman H Lee, Alan Kozikowski, and Alejandro Villagra

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Nonhomologous end joining key factor XLF enhances both 5-florouracil and oxaliplatin resistance in colorectal cancer., Zhuo Liu, Miao Yu, Bingyuan Fei, Jing Sun, and Dongxin Wang

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ERK Regulates HIF1α-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer., Zhuqing Li, Wei Zhou, Yi Zhang, Wei Sun, Mingo M H Yung, Jing Sun, Jing Li, Chi-Wei Chen, Zongzhu Li, Yunxiao Meng, Jie Chai, Yuan Zhou, Stephanie S Liu, Annie N Y Cheung, Hextan Y S Ngan, David W Chan, Wei Zheng, and Wenge Zhu

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ERK Regulates HIF1α-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer., Zhuqing Li, Wei Zhou, Yi Zhang, Wei Sun, Mingo M H Yung, Jing Sun, Jing Li, Chi-Wei Chen, Zongzhu Li, Yunxiao Meng, Jie Chai, Yuan Zhou, Stephanie S Liu, Annie N Y Cheung, Hextan Y S Ngan, David W Chan, Wei Zheng, and Wenge Zhu

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ERK Regulates HIF1α-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer, Zhuqing Li, Wei Zhou, Yi Zhang, Wei Sun, Mingo M H Yung, Jing Sun, Jing Li, Chi-Wei Chen, Zongzhu Li, Yunxiao Meng, Jie Chai, Yuan Zhou, Stephanie S. Liu, Annie N Y Cheung, Hextan Y S Ngan, David W. Chan, Wei Zheng, and Wenge Zhu

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ERK regulates HIF-1α-mediated platinum resistance by directly targeting PHD2 in ovarian cancer., Zhuqing Li, Wei Zhou, Yi Zhang, Wei Sun, Mingo Mh Yung, Jing Sun, Jing Li, Chi-Wei Chen, Zongzhu Li, Yunxiao Meng, Jie Chai, Yuan Zhou, Stephanie Si Liu, Annie Nga-Yin Cheung, Hextan Yuen-Sheung Ngan, David Wai Chan, Wei Zheng, and Wenge Zhu

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The deubiquitylating enzyme USP15 regulates homologous recombination repair and cancer cell response to PARP inhibitors., Yihan Peng, Qingchao Liao, Wei Tan, Changmin Peng, Zhaohua Hu, Yali Chen, Zhuqing Li, Jing Li, Bei Zhen, Wenge Zhu, Xiangpan Li, Yi Yao, Qibin Song, Chengsheng Liu, Xiangdong Qi, Fuchu He, and Huadong Pei

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Phenotypic Subgrouping and Multi-Omics Analyses Reveal Reduced Diazepam-Binding Inhibitor (DBI) Protein Levels in Autism Spectrum Disorder with Severe Language Impairment., Chatravee Pichitpunpong, Surangrat Thongkorn, Songphon Kanlayaprasit, Wasana Yuwattana, Waluga Plaingam, Siriporn Sangsuthum, Wan Mohd Aizat, Syarul Nataqain Baharum, Tewin Tencomnao, Valerie Wailin Hu, and Tewarit Sarachana

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Emerging roles of histone modifications and HDACs in RNA splicing., Raneen Rahhal and Edward Seto

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Thymosin β4 promotes autophagy and repair via HIF-1α stabilization in chronic granulomatous disease., Giorgia Renga, Vasilis Oikonomou, Silvia Moretti, Claudia Stincardini, Marina M Bellet, Marilena Pariano, Andrea Bartoli, Stefano Brancorsini, Paolo Mosci, Andrea Finocchi, Paolo Rossi, Claudio Costantini, Enrico Garaci, Allan L Goldstein, and Luigina Romani

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Akt1 and Akt2 Isoforms Play Distinct Roles in Regulating the Development of Inflammation and Fibrosis Associated with Alcoholic Liver Disease., Karina Reyes-Gordillo, Ruchi Shah, Jaime Arellanes-Robledo, Ying Cheng, Joseph Ibrahim, and Pamela L Tuma

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HDAC8 affects MGMT levels in glioblastoma cell lines, Irene Santos-Barriopedro, Yixuan Li, Sonali Bahl, and Edward Seto

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HDAC8 affects MGMT levels in glioblastoma cell lines, Irene Santos-Barriopedro, Yixuan Li, Sonali Bahl, and Edward Seto

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HDAC8 affects MGMT levels in glioblastoma cell lines, Irene Santos-Barriopedro, Yixuan Li, Sonali Bahl, and Edward Seto

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HDAC8 affects MGMT levels in glioblastoma cell lines via interaction with the proteasome receptor ADRM1, Irene Santos-Barriopedro, Yixuan Li, Sonali Bahl, and Edward Seto

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Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models., Sida Shen, Melissa Hadley, Kseniya Ustinova, Jiri Pavlicek, Tessa Knox, Satish Noonepalle, Mauricio T. Tavares, Chad A. Zimprich, Guiping Zhang, Matthew B. Robers, Cyril Bařinka, Alan P. Kozikowski, and Alejandro Villagra

Microbiota of MR1 deficient mice confer resistance against Clostridium difficile infection, Ashley D. Smith, Elissa D. Foss, Irma Zhang, Jessica L. Hastie, Nicole P. Giordano, Lusine Gasparyan, Lam Phuc VinhNguyen, Alyxandria M. Schubert, Deepika Prasad, Hannah L. McMichael, Jinchun Sun, Richard D. Beger, Vahan Simonyan, Siobhán C. Cowley, and Paul E. Carlson

Microbiota of MR1 deficient mice confer resistance against Clostridium difficile infection, Ashley D. Smith, Elissa D. Foss, Irma Zhang, Jessica L. Hastie, Nicole P. Giordano, Lusine Gasparyan, Lam Phuc VinhNguyen, Alyxandria M. Schubert, Deepika Prasad, Hannah L. McMichael, Jinchun Sun, Richard D. Beger, Vahan Simonyan, Siobhán C. Cowley, and Paul E. Carlson

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The Nuclear Export and Ubiquitin-Proteasome-Dependent Degradation of PPARγ Induced By Angiotensin II., Li Sun and Ka Bian

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Sex Differences in the Effects of Prenatal Bisphenol A Exposure on Genes Associated with Autism Spectrum Disorder in the Hippocampus., Surangrat Thongkorn, Songphon Kanlayaprasit, Depicha Jindatip, Tewin Tencomnao, Valerie W Hu, and Tewarit Sarachana

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PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy., Xinyi Tu, Bo Qin, Yong Zhang, Cheng Zhang, Mohamed Kahila, Somaira Nowsheen, Ping Yin, Jian Yuan, Huadong Pei, Hu Li, Jia Yu, Zhiwang Song, Qin Zhou, Fei Zhao, Jiaqi Liu, Chao Zhang, Haidong Dong, Robert W Mutter, and Zhenkun Lou

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Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment., Rocio G Urdinguio, Virginia Lopez, Gustavo F Bayón, Rafael Diaz de la Guardia, Marta I Sierra, Estela García-Toraño, Raúl F Perez, María G García, Antonella Carella, Patricia C Pruneda, Cristina Prieto, Marija Dmitrijeva, Pablo Santamarina, Thalía Belmonte, Cristina Mangas, Elena Diaconu, Cecilia Ferrero, Juan Ramón Tejedor, Juan Luis Fernandez-Morera, Cristina Bravo, Clara Bueno, Alejandra Sanjuan-Pla, Ramon M Rodriguez, Beatriz Suarez-Alvarez, Carlos López-Larrea, Teresa Bernal, Enrique Colado, Milagros Balbín, Olivia García-Suarez, María Dolores Chiara, Inés Sáenz-de-Santa-María, Francisco Rodríguez, Ana Pando-Sandoval, Luis Rodrigo, Laura Santos, Ana Salas, Jesús Vallejo-Díaz, Ana C Carrera, Daniel Rico, Inmaculada Hernández-López, Amparo Vayá, José M Ricart, Edward Seto, Núria Sima-Teruel, Alejandro Vaquero, Luis Valledor, Maria Jesus Cañal, David Pisano, Osvaldo Graña-Castro, Tim Thomas, Anne K Voss, Pablo Menéndez, Ana Villar-Garea, Rainer Deutzmann, Agustín F Fernandez, and Mario F Fraga

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Soluble ICAM 1 and VCAM 1 Blood Levels Alert on Subclinical Atherosclerosis in Non Smokers with Asymptomatic Metabolic Syndrome, Jose F. Varona, Roberto Ortiz-Regalón, Isabel Sánchez-Vera, Beatriz López-Melgar, Cira García-Durango, José María Castellano Vázquez, Jorge M. Solis, Leticia Fernández-Friera, and Fernando Vidal-Vanaclocha

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MiR-30a regulates cancer cell response to chemotherapy through SNAI1/IRS1/AKT pathway., Tingting Wang, Gang Chen, Xuemei Ma, Yao Yang, Yali Chen, Yihan Peng, Zhigang Bai, Zhongtao Zhang, Huadong Pei, and Wei Guo

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An efficient prototype method to identify and correct misspellings in clinical text., T Elizabeth Workman, Yijun Shao, Guy Divita, and Qing Zeng-Treitler

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Identification of the PTEN-ARID4B-PI3K pathway reveals the dependency on ARID4B by PTEN-deficient prostate cancer, Ray-Chang Wu, In-Chi Young, Yu-Fang Chen, Sung-Ting Chuang, Antoun Toubaji, and Mei-Yi Wu

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Metastasis suppressor NME1 promotes non-homologous end joining of DNA double-strand breaks., Renyu Xue, Yihan Peng, Baolin Han, Xiangpan Li, Yali Chen, and Huadong Pei

Novel reference genes in colorectal cancer identify a distinct subset of high stage tumors and their associated histologically normal colonic tissues, Lai Xu, Helen Luo, Rong Wang, Wells W. Wu, Je Nie Phue, Rong Fong Shen, Hartmut Juhl, Leihong Wu, Wei Lun Alterovitz, Vahan Simonyan, Lorraine Pelosof, and Amy S. Rosenberg