Submissions from 2016
Potential role of p21 Activated Kinase 1 (PAK1) in the invasion and motility of oral cancer cells., Muraleedharan Parvathy, Sreeharshan Sreeja, Rakesh Kumar, and M. Radhakrishna Pillai
Oxidative stress, cellular senescence and ageing, Akshaj Pole, Manjari Dimri, and Goberdhan P. Dimri
Low-ω3 Fatty Acid and Soy Protein Attenuate Alcohol-Induced Fatty Liver and Injury by Regulating the Opposing Lipid Oxidation and Lipogenic Signaling Pathways., Karina Reyes-Gordillo, Ruchi Shah, Ravi Varatharajalu, Mamatha Garige, Leslie C. Leckey, and M. Raj Lakshman
The Complementary and Divergent Roles of Uncoupling Proteins 1 and 3 in thermoregulation., Christopher L Riley, Christine Dao, M Alexander Kenaston, Luigina Muto, Shohei Kohno, Sara M Nowinski, Ashley D Solmonson, Matthew Pfeiffer, Michael N Sack, Zhongping Lu, Giuseppe Fiermonte, Jon E Sprague, and Edward M Mills
The glucose metabolite methylglyoxal inhibits expression of the glucose transport genes by inactivating the cell surface glucose sensors Rgt2 and Snf3 in yeast, Adhiraj Roy, Salman Hashmi, Zerui Li, Angela Dement, Kyu Hong Cho, and Jeong-Ho Kim
Molecular and behavioral profiling of Dbx1-derived neurons in the arcuate, lateral and ventromedial hypothalamic nuclei., Katie Sokolowski, Tuyen Tran, Shigeyuki Esumi, Yasmin Kamal, Livio Oboti, Julieta Lischinsky, Meredith Goodrich, Andrew Lam, Margaret Carter, Yasushi Nakagawa, and Joshua Corbin
Thymosin Beta 4: A Potential Novel Therapy for Neurotrophic Keratopathy, Dry Eye, and Ocular Surface Diseases., G Sosne, D Rimmer, H K. Kleinman, and G Ousler
Epigenetic regulation of soluble guanylate cyclase (sGC) β1 in breast cancer cells., Alex Sotolongo, Fabiola Zakia Mónica, Alex Kots, Haijie Xiao, Jun Liu, Edward Seto, Ka Bian, and Ferid Murad
Protective Role of Dietary Curcumin in the Prevention of the Oxidative Stress Induced by Chronic Alcohol with respect to Hepatic Injury and Antiatherogenic Markers, Ravi Varatharajalu, Mamatha Garige, Leslie C Leckey, Karina Reyes-Gordillo, Ruchi Shah, and M. Raj Lakshman
Identification of genes that are essential to restrict genome duplication to once per cell division., Alex Vassilev, Chrissie Y. Lee, Boris Vassilev, Wenge Zhu, Pinar Ormanoglu, Scott E. Martin, and Melvin L. DePamphilis
A Sensitive and Flexible Assay for Determining Histone Deacetylase 1 (HDAC1) Activity., Mei-Yi Wu and Ray-Chang Wu
Inhibition of nuclear factor-kappa B enhances the tumor growth of ovarian cancer cell line derived from a low-grade papillary serous carcinoma in p53-independent pathway, Xue Xiao, Gong Yang, Peng Bai, Shunping Gui, Tri M. Bui Nguyen, and +8 additional authors
Impact of germline and somatic missense variations on drug binding sites., C Yan, N Pattabiraman, J Goecks, P Lam, A Nayak, Y Pan, J Torcivia-Rodriguez, A Voskanian, Q Wan, and Raja Mazumder
Stabilizing the cold plasma-stimulated medium by regulating medium’s composition, Dayun Yan, Niki Nourmohammadi, Ka Bian, Ferid Murad, Jonathan H. Sherman, and Michael Keidar
Effects of Viola yedoensis Makino anti-itching compound on degranulation and cytokine generation in RBL-2H3 mast cells., Hai-Rong Zeng, Bing Wang, Zhen Zhao, Qi Zhang, Mei-Yun Liang, Ya-Qi Yao, Ka Bian, and Wei-Rong Zhang
Submissions from 2015
Epigenetic biomarkers in liver cancer, Krishna K. Banaudha and Mukesh Verma
What is next in nitric oxide research? From cardiovascular system to cancer biology, Ka Bian and Ferid Murad
Design of a Novel 3D Printed Bioactive Nanocomposite Scaffold for Improved Osteochondral Regeneration., Nathan J Castro, Romil Patel, and Lijie Grace Zhang
Cold Plasma Accelerates the Uptake of Gold Nanoparticles Into Glioblastoma Cells, Xiaoqian Cheng, Kenan Rajjoub, Jonathan H. Sherman, Jerome Canady, Nina Recek, Dayun Yan, Ka Bian, Ferid Murad, and Michael Keidar
MicroRNA-31 is a transcriptional target of histone deacetylase inhibitors and a regulator of cellular senescence, Joon-Ho Cho, Manjari Dimri, and Goberdhan P. Dimri
Cis-encoded non-coding antisense RNAs in streptococci and other low GC Gram (+) bacterial pathogens, Kyu Hong Cho and Jeong-Ho Kim
Targeting metastatic breast cancer: problems and potential [version 1; referees: 5 approved], Sarah Deasy, Karol Szczepanek, and Kent Hunter
Loss of function mutations in PTPN6 promote STAT3 deregulation via JAK3 kinase in diffuse large B-cell lymphoma, Christos Demosthenous, Jing Jing Han, Guangzhen Hu, Mary Stenson, and Mamta Gupta
Translation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma, Christos Demosthenous, Jing Jing Han, Mary J. Stenson, Matthew J. Maurer, Linda E. Wellik, Brian Link, Kristen Hege, Ahmet Dogan, Eduardo Sotomayor, Thomas Witzig, and Mamta Gupta
PLK1 inhibition downregulates polycomb group protein BMI1 via modulation of the miR-200c/141 cluster, Manjari Dimri, Joon-Ho Cho, Mingu Kang, and Goberdhan P. Dimri
A transgenic resource for conditional competitive inhibition of conserved Drosophila microRNAs., Tudor A Fulga, Elizabeth M McNeill, Richard Binari, Julia Yelick, Alexandra Blanche, Matthew Booker, Bruno R Steinkraus, Michael Schnall-Levin, Yong Zhao, Todd DeLuca, Fernando Bejarano, Zhe Han, Eric C Lai, Dennis P Wall, Norbert Perrimon, and David Van Vactor
TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis., Lei Gao, Dantong Li, Ke Ma, Wenjuan Zhang, Tao Xu, Wenge Zhu, and +12 additional authors
Advances in the basic and clinical applications of thymosin β4., Allan L Goldstein and Hynda K Kleinman
And-1 coordinates with Claspin for efficient Chk1 activation in response to replication stress., Jing Hao, Christelle de Renty, Yongming Li, Haijie Xiao, Michael G Kemp, Zhiyong Han, Melvin L DePamphilis, and Wenge Zhu
Investigation of sex differences in the expression of RORA and its transcriptional targets in the brain as a potential contributor to the sex bias in autism, Valerie Wailin Hu, Tewarit Sarachana, Rachel M. Sherrard, and Kristen M. Kocher
The Role of the Pleckstrin Homology Domain-Containing Protein CKIP-1 in Activation of p21-activated Kinase 1 (PAK1), Yong-Bae Kim, Yong Jae Shin, Adhiraj Roy, and Jeong-Ho Kim
Advantages of distributed and parallel algorithms that leverage Cloud Computing platforms for large-scale genome assembly, Phil Kumari, Raja Mazumder, Vahan Simonyan, and Konstantinos Krampis
Synergy between NAFLD and AFLD and potential biomarkers., M. Raj Lakshman, Ruchi Shah, Karina Reyes-Gordillo, and Ravi Varatharajalu
Unravelling the Complexity and Functions of MTA Coregulators in Human Cancer., Da-Qiang Li and Rakesh Kumar
Prolonged Fasting Identifies Heat Shock Protein 10 as a Sirtuin 3 Substrate: Elucidating a New Mechanism Linking Mitochondrial Protein Acetylation to Fatty Acid Oxidation Enzyme Folding and Function, Zhongping Lu, Yong Chen, Angel M. Aponte, Valentina Battaglia, Marjan Gucek, and Michael N. Sack
EGFR-TKI, erlotnib, causes hypomagnesemia, oxidative stress and cardiac dysfunction: Attentuation by NK-1 receptor blockade, I. Tong Mak, Jay H. Kramer, Joanna J. Chmielinska, Christopher F. Spurney, and William B. Weglicki
Vitamin D deficiency in patients with intestinal malabsorption syndromes – think in and outside the gut, Samantha L. Margulies, Divya Kurian, Mark S. Elliott, and Zhiyong Han
MTA1 regulation of ERβ pathway in salivary gland carcinoma cells., Kazufumi Ohshiro and Rakesh Kumar
Is there pandemic vitamin D deficiency in the black population? A review of evidence, Ria S. Roberts, Fafa Huberta Koudoro, Mark S. Elliott, and Zhiyong Han
Assessing Glucose Uptake through the Yeast Hexose Transporter 1 (Hxt1), Adhiraj Roy, Angela D. Dement, Kyu Hong Cho, and Jeong-Ho Kim
The Genus Cerion (Gastropoda: Cerionidae) in the Florida Keys., Yesha Shrestha, Herman H. Wirshing, and M. G. Harasewych
Primary Mechanisms of Thymosin β4 Repair Activity in Dry Eye Disorders and Other Tissue Injuries, Gabriel Sosne and Hynda K. Kleinman
The global cancer genomics consortium's symposium: new era of molecular medicine and epigenetic cancer medicine - cross section of genomics and epigenetics, Masakazu Toi, M. Radhakrishna Pillai, Sudeep Gupta, Rajendra Badwe, Maria Carmo-Fonseca, Luis Costa, Loius W.C. Chow, Stefan Knapp, and Rakesh Kumar
The quick demise of a nineteenth-century Jewish hospital in London, Jack Vanderhoek
Viral non-coding RNA inhibits HNF4α expression in HCV associated hepatocellular carcinoma., Zhao Wang, Kristin Ceniccola, Liliana Florea, Bi-Dar Wang, Norman H Lee, and Ajit Kumar
HCV infection-associated hepatocellular carcinoma in humanized mice., Zhao Wang, Ningbin Wu, Abeba Tesfaye, Stephen Feinstone, and Ajit Kumar
BioXpress: an integrated RNA-seq-derived gene expression database for pan-cancer analysis., Quan Wan, Hayley Dingerdissen, Yu Fan, Naila Gulzar, Yang Pan, Tsung-Jung Wu, Cheng Yan, Haichen Zhang, and Raja Mazumder
The mTORC1 inhibitor everolimus has antitumor activity in vitro and produces tumor responses in patients with relapsed T-cell lymphoma, Thomas E. Witzig, Craig Reeder, Jing Jing Han, Betsy LaPlant, Mary Stenson, Han W. Tun, William Macon, Stephen M. Ansell, Thomas M. Habermann, David J. Inwards, Ivana N. Micallef, Patrick B. Johnston, Luis F. Porrata, Joseph P. Colgan, Svetomir Markovic, Grzegorz S. Nowakowski, and Mamta Gupta
Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis., Ray-Chang Wu, Yang Zeng, I-Wen Pan, and Mei-Yi Wu
AR Coactivator ARID4B is Required for the Function of Sertoli Cells in Spermatogenesis., Ray-Chang Wu, Yang Zeng, I-Wen Pan, and Mei-Yi Wu
Generating a focused view of disease ontology cancer terms for pan-cancer data integration and analysis., Tsung-Jung Wu, Lynn M. Schriml, Qing-Rong Chen, Maureen Colbert, Daniel J. Crichton, Raja Mazumder, Ying Hu, and + 10 more
Anti-Inflammatory Effect of 1,3,5,7-Tetrahydroxy-8-isoprenylxanthone Isolated from Twigs of Garcinia esculenta on Stimulated Macrophage., Dan-Dan Zhang, Hong Zhang, Yuan-Zhi Lao, Rong Wu, Jin-Wen Xu, Ferid Murad, Ka Bian, and Hong-Xi Xu
UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop., Xiao-Wei Zhang, Xiao-Feng Wang, Su-Jie Ni, Wei Qin, Li-Qin Zhao, Rui-Xi Hua, You-Wei Lu, Jin Li, Goberdhan P. Dimri, and Wei-Jian Guo
The importance of GLP-1 and PYY in resistant starch's effect on body fat in mice., June Zhou, Roy J Martin, Anne M Raggio, Li Shen, Kathleen McCutcheon, and Michael J Keenan
Submissions from 2014
Single-nucleotide variations in cardiac arrhythmias: Prospects for genomics and proteomics based biomarker discovery and diagnostics, Ayman Abunimer, Krista Smith, Tsung-Jung Wu, Phuc Lam, Vahan Simonyan, and Raja Mazumder
Germ-line variants of human N-methylpurine DNA glycosylase show impaired DNA repair activity and facilitate 1,N6 ethenoadenine induced mutations., Sanjay Adhikari, Mahandranauth A. Chetram, Jordan Woodrick, Partha S. Mitra, Praveen V. Manthena, Pooja Khatkar, Sivanesan Dakshanamurthy, Monica Dixon, Soumendra K. Karmahapatra, Nikhil K. Nuthalapati, Suhani Gupta, Ganga Narasimhan, Raja Mazumder, Christopher A. Loffredo, Aykut Uren, and Rabindra Roy
Matrigel: From discovery and ECM mimicry to assays and models for cancer research, Gabriel Benton, Irina Arnoutova, Jay George, Hynda K. Kleinman, and Jennifer E. Koblinski
sGC-cGMP signaling: Target for anticancer therapy, Ka Bian and Ferid Murad
The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer, Dimple Chakravarty, Andrea Sboner, Sujit S. Nair, Eugenia Giannopoulou, Ruohan Li, and +16 additional authors
The effect of tuning cold plasma composition on glioblastoma cell viability, Xiaoqian Cheng, Jonathan H. Sherman, William Murphy, Edward Ratovitski, Jerome Canady, and Michael Keidar
Mg supplementation protects against ritonavir-mediated endothelial oxidative stress and hepatic eNOS downregulation, Xi Chen and I. Tong Mak
Non-synonymous variations in cancer and their effects on the human proteome: workflow for NGS data biocuration and proteome-wide analysis of TCGA data, Charles Cole, Konstantinos Krampis, Konstantinos Karagiannis, Jonas Almeida, William J. Faison, Mona Motwani, Quan Wan, Anton Golikov, Yang Pan, Vahan Simonyan, and Raja Mazumder
The global cancer genomics consortium's third annual symposium: From oncogenomics to cancer care, Luis Costa, Sandra Casimiro, Sudeep Gupta, Stefan Knapp, M. Radhakrishna Pillai, Mazakazu Toi, Rajendra Badwe, Maria Carmo-Fonesca, and Rakesh Kumar
Discrete conformations of epitope II on the hepatitis C virus E2 protein for antibody-mediated neutralization and nonneutralization, Lu Deng, Li Ma, Lilin Zhong, Hailing Yan, Zhong Zhao, Evi Struble, Stephen Feinstone, Harvey Alter, and Pei Zhang
Cancer and the ageing process, Manjari Dimri and Goberdhan P. Dimri
A framework for application of metabolic modeling in yeast to predict the effects of nsSNV in human orthologs, Hayley Dingerdissen, Daniel S. Weaver, Peter D. Karp, Yang Pan, Vahan Simonyan, and Raja Mazumder
Whole genome single-nucleotide variation profile-based phylogenetic tree building methods for analysis of viral, bacterial and human genomes, William J. Faison, Alexandre Rostovtsev, Eduardo Castro-Nallar, Keith Crandall, Konstantin Chumakov, Vahan Simonyan, and Raja Mazumder
The long non-coding RNA GAS5 cooperates with the eukaryotic translation initiation factor 4E to regulate c-Myc translation, Guangzhen Hu, Zhenkun Lou, and Mamta Gupta
Frontiers in Autism Research : New Horizons for Diagnosis and Treatment, Valerie Wailin Hu
Role of hepatitis C virus inducted osteopontin in epithelial to mesenchymal transition, migration, and invasion of hepatocytes, Jawed Iqbal, Steven McRae, Thi Mai, Krishna Banaudha, Mehuli Sarkar-Dutta, and Gulam Waris
Novel modulators of hepatosteatosis, inflammation and fibrogenesis., M Raj Lakshman, Karina Reyes-Gordillo, Ravi Varatharajalu, Jaime Arellanes-Robledo, Leslie C Leckey, Mamatha Garige, and Ruchi Shah
MTA family of proteins in DNA damage response: mechanistic insights and potential applications, Da-Qiang Li, Yinlong Yang, and Rakesh Kumar
Advance in studies on molecular mechanisms of cisplatin resistance and intervention with traditional Chinese medicines, L. Liu and Ka Bian
Role of MTA1 in head and neck cancers, Hezlin Marzook, S. Deivendran, Rakesh Kumar, and M. Radhakrishna Pillai
SNPlice: Variants that Modulate Intron-retention from RNA-sequencing Data, Prakriti Mudvari, Mercedeh Movassagh, Kamran Kowsari, Ali Seyfi, Maria Kokkinaki, Nathan J. Edwards, Nady Golestaneh, and Anelia Horvath
Structure-function analysis of hepatitis C virus envelope glycoproteins E1 and E2, Aparajita Nayak, Nagarajan Pattabiraman, Numrah Fadra, Radoslav Goldman, and Raja Mazumder
Human germline and pan-cancer variomes and their distinct functional profiles, Yang Pan, Konstantinos Karagiannis, Haichen Zhang, Hayley Dingerdissen, Amirhossein Shamsaddini, Quan Wan, Vahan Simonyan, and Raja Mazumder
Understanding the mechanism of glucose-induced relief of Rgt1-mediated repression in yeast, Adhiraj Roy, David Jouandot, Kyu Hong Cho, and Jeong-Ho Kim
Glucose starvation-induced turnover of the yeast glucose transporter Hxt1, Adhiraj Roy, Yong-Bae Kim, Kyu Hong Cho, and Jeong-Ho Kim
Cytosolic functions of MORC2 in lipogenesis and adipogenesis, Beatriz Sanchez-Solana, Da-Qiang Li, and Rakesh Kumar
HIVE-hexagon: High-performance, parallelized sequence alignment for next-generation sequencing data analysis, Luis Santana-Quintero, Hayley Dingerdissen, Jean Thierry-Mieg, Raja Mazumder, and Vahan Simonyan
Census-based rapid and accurate metagenome taxonomic profiling, Amirhossein Shamsaddini, Yang Pan, W. Evan Johnson, Konstantinos Krampis, Mariya Shcheglovitova, Vahan Simonyan, Amy Zanne, and Raja Mazumder
Alpha-asarone protects endothelial cells from injury by angiotensin II, Ha-Xia Shi, Jiajun Yang, Tao Yang, Yong-Liang Xue, Jun Liu, Ya-Juan Li, Dan-Dan Zhang, Ji-Wen Zhu, and Ka Bian
Drugs for macular degeneration, price discrimination, and Medicare's responsibility to overpay, Jonathan Silver
High-performance integrated virtual environment (HIVE) tools and applications for big data analysis, Vahan Simonyan and Raja Mazumder
Elevated soluble IL-2Rα, IL-8, and MIP-1β levels are associated with inferior outcome and are independent of MIPI score in patients with mantle cell lymphoma, Mohamad B. Sonbol, Matthew J. Maurer, Mary J. Stenson, Cristine Allmer, Betsy R. Laplant, George J. Weiner, William R. Macon, James R. Cerhan, Thomas E. Witzig, and Mamta Gupta
Increased copy number of the DLX4 homeobox gene in breast axillary lymph node metastasis, Clarissa Torresan, Marcia M.C. Oliveira, Silma R.F. Pereira, Enilze M.S.F. Ribeiro, Catalin Marian, Yuriy Gusev, Rubens S. Lima, Cicero A. Urban, Patricia A. Berg, Bassem R. Haddad, Iglenir J. Cavalli, and Luciane R. Cavalli
Adverse signaling of scavenger receptor class B1 and PGC1s in alcoholic hepatosteatosis and steatohepatitis and protection by betain in rat, Ravi Varatharajalu, Mamatha Garige, Leslie A. Leckey, Jaime Arellanes-Robledo, Karina Reyes-Gordillo, Ruchi Shah, and M. Raj Lakshman
ERK3 promotes endothelial cell functions by upregulating SRC-3/SP1-mediated VEGFR2 expression, Wei Wang, Ka Bian, Sreeram Vallabhaneni, Bin Zhang, Ray-Chang Wu, Bert W. O'Malley, and Weiwen Long
Epigenetic mechanisms of protein tyrosine phosphatase 6 suppression in diffuse large B-cell lymphoma: Implications for epigenetic therapy, T. E. Witzig, G. Hu, S. M. Offer, L. E. Wellik, J. J. Han, M. J. Stenson, A. Dogan, R. B. Diasio, and M. Gupta
Elevated monoclonal and polyclonal serum immunoglobulin free light chain as prognostic factors in B- and T-cell non-Hodgkin lymphoma, Thomas E. Witzig, Matthew J. Maurer, Thomas M. Habermann, Brian K. Link, Ivana N.M. Micallef, Grzegorz S. Nowakowski, Stephen M. Ansell, Joseph P. Colgan, David J. Inwards, Luis F. Porrata, Svetomir N. Markovic, Patrick B. Johnston, Yi Lin, Carrie Thompson, Mamta Gupta, Jerry A. Katzmann, and James R. Cerhan
Elevated serum monoclonal and polyclonal free light chains and interferon inducible protein-10 predicts inferior prognosis in untreated diffuse large B-cell lymphoma, Thomas E. Witzig, Matthew J. Maurer, Mary J. Stenson, Cristine Allmer, William Macon, Brian Link, Jerry A. Katzmann, and Mamta Gupta
MiR-34a regulates therapy resistance by targeting HDAC1 and HDAC7 in breast cancer, Mei-Yi Wu, Junjiang Fu, Xiuli Xiao, Jingbo Wu, and Ray-Chang Wu
A framework for organizing cancer-related variations from existing databases, publications and NGS data using a High-performance Integrated Virtual Environment (HIVE), Tsung-Jung Wu, Amirhossein Shamsaddini, Yang Pan, Krista Smith, Daniel J. Chrichton, Vahan Simonyan, and Raja Mazumder
Effects of rutaecarpine on inflammatory cytokines in insulin resistant primary skeletal muscle cells, J Yang, X. Nie, H. Shi, Y. Zhang, J. Zhang, Y. Yuan, and Ka Bian
Submissions from 2013
Fibrogenic actions of acetaldehyde are β-catenin dependent but Wingless independent: A critical role of nucleoredoxin and reactive oxygen species in human hepatic stellate cells, Jaime Arellanes-Robledo, Karina Reyes-Gordillo, Ruchi Shah, Jose Alfredo Dominguez-Rosales, Zamira Hernandez-Nazara, Francesco Ramirez, Marcos Rojkind, and M. Raj Lakshman
Community annotation and the evolution of cooperation: How patience matters, Atin Basuchoudhary, Vahan Simoyan, and Raja Mazumder
CKAP2 ensures chromosomal stability by maintaining the integrity of microtubule nucleation sites, Chanelle M. Case, Dan L. Sackett, Danny Wangsa, Tatiana S. Karpova, James G. McNally, Thomas Ried, and Jordi Camps
A positive feedback loop regulates the expression of polycomb group protein BMI1 via WNT signaling pathway, Joon-Ho Cho, Manjari Dimri, and Goberdhan P. Dimri
The prince and the pauper: Which one is real?: The problem of secondary mutation during mutagenesis in Streptococcus pyogenes, Kyu Hong Cho, Jordan O. Wright, Juan P. Svencionis, and Jeong-Ho Kim