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Submissions from 2020

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Novel miRNA Targets and Therapies in the Triple-Negative Breast Cancer Microenvironment: An Emerging Hope for a Challenging Disease., Amal Qattan

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Thymosin α1 protects from CTLA-4 intestinal immunopathology., Giorgia Renga, Marina M Bellet, Marilena Pariano, Marco Gargaro, Claudia Stincardini, Fiorella D'Onofrio, Paolo Mosci, Stefano Brancorsini, Andrea Bartoli, Allan L. Goldstein, Enrico Garaci, Luigina Romani, and Claudio Costantini

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GeTallele: A Method for Analysis of DNA and RNA Allele Frequency Distributions., Piotr Słowiński, Muzi Li, Paula Restrepo, Nawaf Alomran, Liam F. Spurr, Christian Miller, Krasimira Tsaneva-Atanasova, and Anelia Horvath

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ReQTL: Identifying correlations between expressed SNVs and gene expression using RNA-sequencing data, Liam F. Spurr, Nawaf Alomran, Pavlos Bousounis, Dacian Reece-Stremtan, N. M. Prashant, Hongyu Liu, Piotr Słowiński, Muzi Li, Qianqian Zhang, Justin Sein, Gabriel Asher, Keith A. Crandall, Krasimira Tsaneva-Atanasova, and Anelia Horvath

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Prenatal exposure to bisphenol A alters the transcriptome-interactome profiles of genes associated with Alzheimer's disease in the offspring hippocampus., Suporn Sukjamnong, Surangrat Thongkorn, Songphon Kanlayaprasit, Thanit Saeliw, Kanlayaphat Hussem, Watis Warayanon, Valerie W. Hu, Tewin Tencomnao, and Tewarit Sarachana

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Evaluation of an angiotensin Type 1 receptor blocker on the reconsolidation of fear memory, Adam P. Swiercz, Laxmi Iyer, Zhe Yu, Allison Edwards, N. M. Prashant, Bryan N. Nguyen, Anelia Horvath, and Paul J. Marvar

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Scanning window analysis of non-coding regions within normal-tumor whole-genome sequence samples., John Torcivia and Raja Mazumder

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A Tale of Two Nineteenth-century Dutch Jewish Hospitals-One a Success, The Other a Failure., Jack Y. Vanderhoek

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Liver prometastatic reaction: Stimulating factors and responsive cancer phenotypes., Fernando Vidal-Vanaclocha, Olatz Crende, Cira García de Durango, Alejandro Herreros-Pomares, Sandra López-Doménech, Álvaro González, Eva Ruiz-Casares, Thierry Vilboux, Riccardo Caruso, Hipólito Durán, Antonio Gil, Benedetto Ielpo, Fernando Lapuente, Yolanda Quijano, Emilio Vicente, Leticia Vidal-Lartitegui, and Eduardo M. Sotomayor

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Genetic ablation of adipocyte PD-L1 reduces tumor growth but accentuates obesity-associated inflammation., Bogang Wu, Huai-Chin Chiang, Xiujie Sun, Bin Yuan, Payal Mitra, Yanfen Hu, Tyler J Curiel, and Rong Li

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PPARγ inhibition boosts efficacy of PD-L1 Checkpoint Blockade Immunotherapy against Murine Melanoma in a sexually dimorphic manner., Bogang Wu, Xiujie Sun, Bin Yuan, Fei Ge, Harshita B Gupta, Huai-Chin Chiang, Jingwei Li, Yanfen Hu, Tyler J. Curiel, and Rong Li

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The 3D genomic landscape of differential response to EGFR/HER2 inhibition in endocrine-resistant breast cancer cells., Yini Yang, Lavanya Choppavarapu, Kun Fang, Alireza S Naeini, Bakhtiyor Nosirov, Jingwei Li, Ke Yang, Zhijing He, Yufan Zhou, Rachel Schiff, Rong Li, Yanfen Hu, Junbai Wang, and Victor X Jin

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GlyGen: Computational and Informatics Resources for Glycoscience., William S York, Raja Mazumder, Rene Ranzinger, Nathan Edwards, Robel Kahsay, Kiyoko F Aoki-Kinoshita, Matthew P Campbell, Richard D Cummings, Ten Feizi, Maria Martin, Darren A Natale, Nicolle H Packer, Robert J Woods, Gaurav Agarwal, Sena Arpinar, Sanath Bhat, Judith Blake, Leyla Jael Garcia Castro, Brian Fochtman, Jeffrey Gildersleeve, Radoslav Goldman, Xavier Holmes, Vinamra Jain, Sujeet Kulkarni, Rupali Mahadik, Akul Mehta, Reza Mousavi, Sandeep Nakarakommula, Rahi Navelkar, Nagarajan Pattabiraman, Michael J Pierce, Karen Ross, Preethi Vasudev, Jeet Vora, Tatiana Williamson, and Wenjin Zhang

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Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression., Li Yu, Bin Zhang, Dinesh Deochand, Maria A Sacta, Maddalena Coppo, Yingli Shang, Ziyi Guo, Xiaomin Zeng, David A Rollins, Bowranigan Tharmalingam, Rong Li, Yurii Chinenov, Inez Rogatsky, and Xiaoyu Hu

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Dysregulated metabolic pathways in age-related macular degeneration., Meng Zhang, Nisi Jiang, Yi Chu, Olga Postnikova, Rency Varghese, Anelia Horvath, Amrita K. Cheema, and Nady Golestaneh

A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing, Wen Wei Zhang, Subir Karmakar, Sreenivas Gannavaram, Ranadhir Dey, Patrick Lypaczewski, Nevien Ismail, Abid Siddiqui, Vahan Simonyan, Fabiano Oliveira, Iliano V. Coutinho-Abreu, Thiago DeSouza-Vieira, Claudio Meneses, James Oristian, Tiago D. Serafim, Abu Musa, Risa Nakamura, Noushin Saljoughian, Greta Volpedo, Monika Satoskar, Sanika Satoskar, Pradeep K. Dagur, J. Philip McCoy, Shaden Kamhawi, Jesus G. Valenzuela, Shinjiro Hamano, Abhay R. Satoskar, Greg Matlashewski, and Hira L. Nakhasi

Submissions from 2019

Codon and Codon-Pair Usage Tables (CoCoPUTs): Facilitating Genetic Variation Analyses and Recombinant Gene Design, Aikaterini Alexaki, Jacob Kames, David D. Holcomb, John Athey, Luis V. Santana-Quintero, Phuc Vihn Nguyen Lam, Nobuko Hamasaki-Katagiri, Ekaterina Osipova, Vahan Simonyan, Haim Bar, Anton A. Komar, and Chava Kimchi-Sarfaty

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The GlySpace Alliance: towards a collaborative global glycoinformatics community., Kiyoko F. Aoki-Kinoshita, Frederique Lisacek, Raja Mazumder, William S. York, and Nicolle H. Packer

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Immunoepigenetics Combination Therapies: An Overview of the Role of HDACs in Cancer Immunotherapy., Debarati Banik, Sara Moufarrij, and Alejandro Villagra

Identification and quantification of defective virus genomes in high throughput sequencing data using DVG-profiler, a novel post-sequence alignment processing algorithm, Trent J. Bosma, Konstantinos Karagiannis, Luis Santana-Quintero, Natalia Ilyushina, Tatiana Zagorodnyaya, Svetlana Petrovskaya, Majid Laassri, Raymond P. Donnelly, Steven Rubin, Vahan Simonyan, and Christian J. Sauder

Is the patient cured?, Harry B. Burke and Scott Kopetz

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Prussian blue nanoparticle-based antigenicity and adjuvanticity trigger robust antitumor immune responses against neuroblastoma., Juliana Cano-Mejia, Michelle L Bookstaver, Elizabeth E Sweeney, Christopher M Jewell, and Rohan Fernandes

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HDAC11 Regulates Type I Interferon Signaling through Defatty-Acylation of SHMT2., Ji Cao, Lei Sun, Pornpun Aramsangtienchai, Nicole A Spiegelman, Xiaoyu Zhang, Weishan Huang, Edward Seto, and Hening Lin

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Stevioside inhibits experimental fibrosis by down-regulating profibrotic Smad pathways and blocking hepatic stellate cell activation., Sael Casas-Grajales, Diana Alvarez-Suarez, Erika Ramos-Tovar, Laura Dayana Buendía-Montaño, Karina Reyes-Gordillo, Javier Camacho, Víctor Tsutsumi, M Raj Lakshman, and Pablo Muriel

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Antioxidant and immunomodulatory activity induced by stevioside in liver damage: In vivo, in vitro and in silico assays., Sael Casas-Grajales, Erika Ramos-Tovar, Esmeralda Chávez-Estrada, Diana Alvarez-Suarez, Erika Hernández-Aquino, Karina Reyes-Gordillo, Carlos M Cerda-García-Rojas, Javier Camacho, Víctor Tsutsumi, M Raj Lakshman, and Pablo Muriel

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Rebaudioside A administration prevents experimental liver fibrosis: an in vivo and in vitro study of the mechanisms of action involved., Sael Casas-Grajales, Karina Reyes-Gordillo, Carlos M Cerda-García-Rojas, Víctor Tsutsumi, M Raj Lakshman, and Pablo Muriel

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Investigation of somatic single nucleotide variations in human endogenous retrovirus elements and their potential association with cancer., Ting-Chia Chang, Santosh Goud, John Torcivia-Rodriguez, Yu Hu, Qing Pan, Robel Kahsay, Jonas Blomberg, and Raja Mazumder

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PES1 is a critical component of telomerase assembly and regulates cellular senescence, Long Cheng, Bin Yuan, Sunyang Ying, Chang Niu, Hongxu Mai, Xin Guan, Xiaohui Yang, Yan Teng, Jing Lin, Junjian Huang, Rui Jin, Jun Wu, Bo Liu, Shaohong Chang, Enqun Wang, Chunxia Zhang, Ning Hou, Xuan Cheng, Danyang Xu, Xiao Yang, Shan Gao, and Qinong Ye

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CRISPR Screening "Big Data" Informs Novel Therapeutic Solutions., Sitong Chen, Lin Yang, and Wei Li

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BRCA1-associated R-loop affects transcription and differentiation in breast luminal epithelial cells, Huai Chin Chiang, Xiaowen Zhang, Jingwei Li, Xiayan Zhao, Jerry Chen, Howard T.H. Wang, Ismail Jatoi, Andrew Brenner, Yanfen Hu, and Rong Li

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Substance P receptor blocker, aprepitant, inhibited cutaneous and other neurogenic inflammation side effects of the EGFR1-TKI, erlotinib., Joanna J. Chmielinska, Jay H. Kramer, I-Tong Mak, Christopher F. Spurney, and William B. Weglicki

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A Reappraisal of Thymosin Alpha1 in Cancer Therapy., Claudio Costantini, Marina M. Bellet, Marilena Pariano, Giorgia Renga, Claudia Stincardini, Allan L. Goldstein, Enrico Garaci, and Luigina Romani

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Engineering a Novel 3D Printed Vascularized Tissue Model for Investigating Breast Cancer Metastasis to Bone., Haitao Cui, Timothy Esworthy, Xuan Zhou, Sung Yun Hann, Robert I. Glazer, Rong Li, and Lijie Grace Zhang

Blockchain: An enabler for healthcare and life sciences transformation, F. Curbera, D. M. Dias, V. Simonyan, W. A. Yoon, and A. Casella

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RNA m6A methyltransferase METTL3 regulates invasiveness of melanoma cells by matrix metallopeptidase 2., Ujwal Dahal, Le Kang, and Mamta Gupta

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17-hydroxy wortmannin restores TRAIL's response by ameliorating increased beclin 1 level and autophagy function in TRAIL-resistant colon cancer cells., Sheng Dai, Shu Yang, Xin Hu, Wei Sun, Gregory Tawa, Wenge Zhu, Aaron D Schimmer, Chao He, Bingliang Fang, Hongbo Zhu, and Wei Zheng

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Senescence-associated beta-galactosidase marker of cellular senescence, Manjari Dimri and Goberdhan P. Dimri

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Mg-supplementation attenuated lipogenic and oxidative/nitrosative gene expression caused by Combination Antiretroviral Therapy (cART) in HIV-1-transgenic rats., Lama ElZohary, William B Weglicki, Joanna J Chmielinska, Jay H Kramer, and I Tong Mak

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HDAC8 regulates a stress response pathway in melanoma to mediate escape from BRAF inhibitor therapy., Michael F Emmons, Fernanda Faião-Flores, Ritin Sharma, Ram Thapa, Jane L Messina, Jurgen C Becker, Dirk Schadendorf, Edward Seto, Vernon K Sondak, John M Koomen, Yian Ann Chen, Eric K Lau, Lixin Wan, Jonathan D Licht, and Keiran S M Smalley

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History of the Discovery of Hepatitis A Virus., Stephen M Feinstone

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Chronic administration of diethylnitrosamine to induce hepatocarcinogenesis and to evaluate its synergistic effect with other hepatotoxins in mice., Sergio Fuentes-Hernández, Brisa Rodope Alarcón-Sánchez, Dafne Guerrero-Escalera, Alexia Viridiana Montes-Aparicio, María Paulette Castro-Gil, Osiris Germán Idelfonso-García, Sandra Rosas-Madrigal, Diana Ivette Aparicio-Bautista, José Luis Pérez-Hernández, Karina Reyes-Gordillo, M Raj Lakshman, Verónica Rocío Vásquez-Garzón, Rafael Baltiérrez-Hoyos, Ma de Lourdes López-González, Adolfo Sierra-Santoyo, Saúl Villa-Treviño, Julio Isael Pérez-Carreón, and Jaime Arellanes-Robledo

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Functional Analysis of HDACs in Tumorigenesis., Melissa Hadley, Satish Noonepalle, Debarati Banik, and Alejandro Villagra

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Insights into the HIV Latency and the Role of Cytokines., Joseph Hokello, Adhikarimayum Lakhikumar Sharma, Manjari Dimri, and Mudit Tyagi

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RIP sequencing in mantle cell lymphoma identifies functional long non-coding RNAs associated with translation machinery., Guangzhen Hu, Yuji Zhang, and Mamta Gupta

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Sirtuin 6 Attenuates Kaposi's Sarcoma-Associated Herpesvirus Reactivation by Suppressing Ori-Lyt Activity and Expression of RTA., Min Hu, Najealicka Armstrong, Edward Seto, Wenwei Li, Fanxiu Zhu, Paul C Wang, and Qiyi Tang

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ASD Phenotype-Genotype Associations in Concordant and Discordant Monozygotic and Dizygotic Twins Stratified by Severity of Autistic Traits., Valerie W. Hu, Christine A. Devlin, and Jessica J. Debski

Mental health comorbidities and cost/utilization outcomes in head and neck cancer patients, Diana D. Jeffery, Lcdr Art Ambrosio, Laura Hopkins, and Harry B. Burke

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Heart Protection by Herb Formula BanXia BaiZhu TianMa Decoction in Spontaneously Hypertensive Rats., Jiaye Jiang, Dan Huang, Yuan Li, Zhongyuan Gan, Hanqing Li, Xindan Li, Ka Bian, and Yan Ke

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Flotillins in the Intercalated Disc are Potential Modulators of Cardiac Excitability., Elise L Kessler, Leonie van Stuijvenberg, Joanne J A van Bavel, Joëlle van Bennekom, Anne Zwartsen, Mathilde R Rivaud, Aryan Vink, Igor R Efimov, Alex V Postma, J Peter van Tintelen, Carol A Remme, Marc A Vos, Antje Banning, Teun P de Boer, Ritva Tikkanen, and Toon A B van Veen

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miCloud: A Plug-n-Play, Extensible, On-Premises Bioinformatics Cloud for Seamless Execution of Complex Next-Generation Sequencing Data Analysis Pipelines., Baekdoo Kim, Thahmina Ali, Changsu Dong, Carlos Lijeron, Raja Mazumder, Claudia Wultsch, and Konstantinos Krampis

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Baseline human gut microbiota profile in healthy people and standard reporting template., Charles H. King, Hiral Desai, Allison C. Sylvetsky, Jonathan LoTempio, Shant Ayanyan, Jill Carrie, Keith A Crandall, Brian C Fochtman, Lusine Gasparyan, Naila Gulzar, Paul Howell, Najy Issa, Konstantinos Krampis, Lopa Mishra, Hiroki Morizono, Joseph R Pisegna, Shuyun Rao, Yao Ren, Vahan Simonyan, Krista Smith, Sharanjit VedBrat, Michael D Yao, and Raja Mazumder

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Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells., Tessa Knox, Eva Sahakian, Debarati Banik, Melissa Hadley, Erica Palmer, Satish Noonepalle, Jennifer Kim, John Powers, Maria Gracia-Hernandez, Vasco Oliveira, Fengdong Cheng, Jie Chen, Cyril Barinka, Javier Pinilla-Ibarz, Norman H Lee, Alan Kozikowski, and Alejandro Villagra

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Nonhomologous end joining key factor XLF enhances both 5-florouracil and oxaliplatin resistance in colorectal cancer., Zhuo Liu, Miao Yu, Bingyuan Fei, Jing Sun, and Dongxin Wang

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Targeting MYC activity in double-hit lymphoma with MYC and BCL2 and/or BCL6 rearrangements with epigenetic bromodomain inhibitors, Weiping Li, Shiv K. Gupta, Weiguo Han, Ryan A. Kundson, Sara Nelson, Darlene Knutson, Patricia T. Greipp, Sherine F. Elsawa, Eduardo M. Sotomayor, and Mamta Gupta

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ERK Regulates HIF1α-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer., Zhuqing Li, Wei Zhou, Yi Zhang, Wei Sun, Mingo M H Yung, Jing Sun, Jing Li, Chi-Wei Chen, Zongzhu Li, Yunxiao Meng, Jie Chai, Yuan Zhou, Stephanie S Liu, Annie N Y Cheung, Hextan Y S Ngan, David W Chan, Wei Zheng, and Wenge Zhu

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Epigenetic therapy for ovarian cancer: Promise and progress, Sara Moufarrij, Monica Dandapani, Elisa Arthofer, Stephanie Gomez, Aneil Srivastava, Micael Lopez-Acevedo, Alejandro Villagra, and Katherine B. Chiappinelli

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Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells, Nigora Mukhamedova, Anh Hoang, Dragana Dragoljevic, Larisa Dubrovsky, Tatiana Pushkarsky, Hann Low, Michael Ditiatkovski, Ying Fu, Ryunosuke Ohkawa, Peter J. Meikle, Anelia Horvath, Beda Brichacek, Yury I. Miller, Andrew Murphy, Michael Bukrinsky, and Dmitri Sviridov

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The deubiquitylating enzyme USP15 regulates homologous recombination repair and cancer cell response to PARP inhibitors., Yihan Peng, Qingchao Liao, Wei Tan, Changmin Peng, Zhaohua Hu, Yali Chen, Zhuqing Li, Jing Li, Bei Zhen, Wenge Zhu, Xiangpan Li, Yi Yao, Qibin Song, Chengsheng Liu, Xiangdong Qi, Fuchu He, and Huadong Pei

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Phenotypic Subgrouping and Multi-Omics Analyses Reveal Reduced Diazepam-Binding Inhibitor (DBI) Protein Levels in Autism Spectrum Disorder with Severe Language Impairment., Chatravee Pichitpunpong, Surangrat Thongkorn, Songphon Kanlayaprasit, Wasana Yuwattana, Waluga Plaingam, Siriporn Sangsuthum, Wan Mohd Aizat, Syarul Nataqain Baharum, Tewin Tencomnao, Valerie Wailin Hu, and Tewarit Sarachana

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Emerging roles of histone modifications and HDACs in RNA splicing., Raneen Rahhal and Edward Seto

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Thymosin β4 promotes autophagy and repair via HIF-1α stabilization in chronic granulomatous disease., Giorgia Renga, Vasilis Oikonomou, Silvia Moretti, Claudia Stincardini, Marina M Bellet, Marilena Pariano, Andrea Bartoli, Stefano Brancorsini, Paolo Mosci, Andrea Finocchi, Paolo Rossi, Claudio Costantini, Enrico Garaci, Allan L Goldstein, and Luigina Romani

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Akt1 and Akt2 Isoforms Play Distinct Roles in Regulating the Development of Inflammation and Fibrosis Associated with Alcoholic Liver Disease., Karina Reyes-Gordillo, Ruchi Shah, Jaime Arellanes-Robledo, Ying Cheng, Joseph Ibrahim, and Pamela L Tuma

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HDAC8 affects MGMT levels in glioblastoma cell lines via interaction with the proteasome receptor ADRM1, Irene Santos-Barriopedro, Yixuan Li, Sonali Bahl, and Edward Seto

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Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models., Sida Shen, Melissa Hadley, Kseniya Ustinova, Jiri Pavlicek, Tessa Knox, Satish Noonepalle, Mauricio T. Tavares, Chad A. Zimprich, Guiping Zhang, Matthew B. Robers, Cyril Bařinka, Alan P. Kozikowski, and Alejandro Villagra

Microbiota of MR1 deficient mice confer resistance against Clostridium difficile infection, Ashley D. Smith, Elissa D. Foss, Irma Zhang, Jessica L. Hastie, Nicole P. Giordano, Lusine Gasparyan, Lam Phuc VinhNguyen, Alyxandria M. Schubert, Deepika Prasad, Hannah L. McMichael, Jinchun Sun, Richard D. Beger, Vahan Simonyan, Siobhán C. Cowley, and Paul E. Carlson

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The Nuclear Export and Ubiquitin-Proteasome-Dependent Degradation of PPARγ Induced By Angiotensin II., Li Sun and Ka Bian

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Sex Differences in the Effects of Prenatal Bisphenol A Exposure on Genes Associated with Autism Spectrum Disorder in the Hippocampus., Surangrat Thongkorn, Songphon Kanlayaprasit, Depicha Jindatip, Tewin Tencomnao, Valerie W Hu, and Tewarit Sarachana

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PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy., Xinyi Tu, Bo Qin, Yong Zhang, Cheng Zhang, Mohamed Kahila, Somaira Nowsheen, Ping Yin, Jian Yuan, Huadong Pei, Hu Li, Jia Yu, Zhiwang Song, Qin Zhou, Fei Zhao, Jiaqi Liu, Chao Zhang, Haidong Dong, Robert W Mutter, and Zhenkun Lou

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Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment., Rocio G Urdinguio, Virginia Lopez, Gustavo F Bayón, Rafael Diaz de la Guardia, Marta I Sierra, Estela García-Toraño, Raúl F Perez, María G García, Antonella Carella, Patricia C Pruneda, Cristina Prieto, Marija Dmitrijeva, Pablo Santamarina, Thalía Belmonte, Cristina Mangas, Elena Diaconu, Cecilia Ferrero, Juan Ramón Tejedor, Juan Luis Fernandez-Morera, Cristina Bravo, Clara Bueno, Alejandra Sanjuan-Pla, Ramon M Rodriguez, Beatriz Suarez-Alvarez, Carlos López-Larrea, Teresa Bernal, Enrique Colado, Milagros Balbín, Olivia García-Suarez, María Dolores Chiara, Inés Sáenz-de-Santa-María, Francisco Rodríguez, Ana Pando-Sandoval, Luis Rodrigo, Laura Santos, Ana Salas, Jesús Vallejo-Díaz, Ana C Carrera, Daniel Rico, Inmaculada Hernández-López, Amparo Vayá, José M Ricart, Edward Seto, Núria Sima-Teruel, Alejandro Vaquero, Luis Valledor, Maria Jesus Cañal, David Pisano, Osvaldo Graña-Castro, Tim Thomas, Anne K Voss, Pablo Menéndez, Ana Villar-Garea, Rainer Deutzmann, Agustín F Fernandez, and Mario F Fraga

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Soluble ICAM 1 and VCAM 1 Blood Levels Alert on Subclinical Atherosclerosis in Non Smokers with Asymptomatic Metabolic Syndrome, Jose F. Varona, Roberto Ortiz-Regalón, Isabel Sánchez-Vera, Beatriz López-Melgar, Cira García-Durango, José María Castellano Vázquez, Jorge M. Solis, Leticia Fernández-Friera, and Fernando Vidal-Vanaclocha

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MiR-30a regulates cancer cell response to chemotherapy through SNAI1/IRS1/AKT pathway., Tingting Wang, Gang Chen, Xuemei Ma, Yao Yang, Yali Chen, Yihan Peng, Zhigang Bai, Zhongtao Zhang, Huadong Pei, and Wei Guo

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An efficient prototype method to identify and correct misspellings in clinical text., T Elizabeth Workman, Yijun Shao, Guy Divita, and Qing Zeng-Treitler

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Identification of the PTEN-ARID4B-PI3K pathway reveals the dependency on ARID4B by PTEN-deficient prostate cancer, Ray-Chang Wu, In-Chi Young, Yu-Fang Chen, Sung-Ting Chuang, Antoun Toubaji, and Mei-Yi Wu

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Metastasis suppressor NME1 promotes non-homologous end joining of DNA double-strand breaks., Renyu Xue, Yihan Peng, Baolin Han, Xiangpan Li, Yali Chen, and Huadong Pei

Novel reference genes in colorectal cancer identify a distinct subset of high stage tumors and their associated histologically normal colonic tissues, Lai Xu, Helen Luo, Rong Wang, Wells W. Wu, Je Nie Phue, Rong Fong Shen, Hartmut Juhl, Leihong Wu, Wei Lun Alterovitz, Vahan Simonyan, Lorraine Pelosof, and Amy S. Rosenberg

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BRCA1 mutations attenuate super-enhancer function and chromatin looping in haploinsufficient human breast epithelial cells., Xiaowen Zhang, Yao Wang, Huai-Chin Chiang, Yuan-Pang Hsieh, Chang Lu, Ben Ho Park, Ismail Jatoi, Victor X Jin, Yanfen Hu, and Rong Li

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Secretome profiling identifies neuron-derived neurotrophic factor as a tumor-suppressive factor in lung cancer., Ya Zhang, Xuefeng Wu, Yan Kai, Chia-Han Lee, Fengdong Cheng, Yixuan Li, Yongbao Zhuang, Javid Ghaemmaghami, Kun-Han Chuang, Zhuo Liu, Yunxiao Meng, Meghana Keswani, Nancy R. Gough, Xiaojun Wu, Wenge Zhu, Alexandros Tzatsos, Weiqun Peng, Edward Seto, Eduardo M. Sotomayor, and Xiaoyan Zheng

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The Cdk2-c-Myc-miR-571 Axis Regulates DNA Replication and Genomic Stability by Targeting Geminin., Yi Zhang, Zhuqing Li, Qiang Hao, Wei Tan, Jing Sun, Jing Li, Chi-Wei Chen, Zongzhu Li, Yunxiao Meng, Yuan Zhou, Zhiyong Han, Huadong Pei, Melvin L DePamphilis, and Wenge Zhu

Submissions from 2018

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Ethanol targets nucleoredoxin/dishevelled interactions and stimulates phosphatidylinositol 4-phosphate production in vivo and in vitro., Jaime Arellanes-Robledo, Karina Reyes-Gordillo, Joseph Ibrahim, Leslie Leckey, Ruchi Shah, and M Raj Lakshman

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HDAC11 suppresses the thermogenic program of adipose tissue via BRD2., Rushita A. Bagchi, Bradley S. Ferguson, Matthew S. Stratton, Tianjing Hu, Maria A. Cavasin, Lei Sun, Ying-Hsi Lin, Dianxin Liu, Pilar Londono, Kunhua Song, Maria F. Pino, Lauren M. Sparks, Steven R. Smith, Philipp E. Scherer, Sheila Collins, Edward Seto, and Timothy A. McKinsey

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Challenges and Opportunities in Social Epigenomics and Cancer., Krishna Banaudha, Vineet Kumar, and Mukesh Verma

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Stevioside Inhibits Experimental Fibrosis by Downregulating Profibrotic Smad Pathways and Blocking HSC Activation., Sael Casas-Grajales, Diana Alvarez-Suarez, Erika Ramos-Tovar, Laura Dayana Buendía-Montaño, Karina Reyes-Gordillo, Javier Camacho, Víctor Tsutsumi, M Raj Lakshman, and Pablo Muriel

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DHS (trans-4,4'-dihydroxystilbene) Suppresses DNA Replication and Tumor Growth by Inhibiting RRM2 (ribonucleotide Reductase Regulatory Subunit M2)., Chi-Wei Chen, Yongming Li, Shuya Hu, Wei Zhou, Yunxiao Meng, Zongzhu Li, Yi Zhang, Jing Sun, Zhou Bo, Melvin L DePamphilis, Yun Yen, Zhiyong Han, and Wenge Zhu

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Gene-Specific Genetic Complementation between Brca1 and Cobra1 During Mouse Mammary Gland Development., Huai-Chin Chiang, Xiaowen Zhang, Xiayan Zhao, Chi Zhang, Jerry Chen, Paula Garza, Sabrina Smith, Thomas Ludwig, Richard J Baer, Rong Li, and Yanfen Hu

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Loss and gain of N-linked glycosylation sequons due to single-nucleotide variation in cancer., Yu Fan, Yu Hu, Cheng Yan, Radoslav Goldman, Yang Pan, Raja Mazumder, and Hayley M Dingerdissen

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Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein BMI1 in breast cancer cells., Joseph E Gergely, Armond E Dorsey, Goberdhan P Dimri, and Manjari Dimri

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DEXTER: Disease-Expression Relation Extraction from Text., Samir Gupta, Hayley Dingerdissen, Karen E Ross, Yu Hu, Cathy H Wu, Raja Mazumder, and K Vijay-Shanker

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Prognostic and Therapeutic Significance of Phosphorylated STAT3 and Protein Tyrosine Phosphatase-6 in Peripheral-T Cell Lymphoma., Jing Jing Han, Megan O'byrne, Mary J Stenson, Matthew J Maurer, Linda E Wellik, Andrew L Feldman, Ellen D McPhail, Thomas E Witzig, and Mamta Gupta

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Elevated GLI3 expression in germinal center diffuse large B cell lymphoma., Weiguo Han, Gabriela Ibarra, Mamta Gupta, Yanbin Yin, and Sherine F Elsawa

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The Comparative Associations of Ultrasound and Computed Tomography Estimates of Muscle Quality with Physical Performance and Metabolic Parameters in Older Men., Michael O Harris-Love, Nilo A Avila, Bernadette Adams, June Zhou, Bryant Seamon, Catheeja Ismail, Syed H Zaidi, Courtney A Kassner, Frank Liu, and Marc R Blackman

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MicroRNA-34 family in breast cancer: from research to therapeutic potential., Saber Imani, Ray-Chang Wu, and Junjiang Fu

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Total Flavonoids from Radix Glycyrrhiza Exert Anti-Inflammatory and Antitumorigenic Effects by Inactivating iNOS Signaling Pathways., Yi-Xin Jiang, Yang-Yi Dai, Yi-Feng Pan, Xi-Min Wu, Yue Yang, Ka Bian, and Dan-Dan Zhang

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RGN-259 (thymosin β4) improves clinically important dry eye efficacies in comparison with prescription drugs in a dry eye model., Chae Eun Kim, Hynda K Kleinman, Gabriel Sosne, George W Ousler, Kyeongsoon Kim, Sinwook Kang, and Jaewook Yang

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Evolution of echovirus 11 in a chronically infected immunodeficient patient., Majid Laassri, Tatiana Zagorodnyaya, Sharon Hassin-Baer, Rachel Handsher, Danit Sofer, Merav Weil, Konstantinos Karagiannis, Vahan Simonyan, Konstantin Chumakov, and Lester Shulman

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Evolution of echovirus 11 in a chronically infected immunodeficient patient., Majid Laassri, Tatiana Zagorodnyaya, Sharon Hassin-Baer, Rachel Handsher, Danit Sofer, Merav Weil, Konstantinos Karagiannis, Vahan Simonyan, Konstantin Chumakov, and Lester Shulman

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Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication., Hongbo Ling, Lirong Peng, Jianbo Wang, Raneen Rahhal, and Edward Seto

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Silencing of HDAC6 as a therapeutic target in chronic lymphocytic leukemia., Kamira Maharaj, John J Powers, Alex Achille, Susan Deng, Renee Fonseca, Mibel Pabon-Saldana, Steven N Quayle, Simon S Jones, Alejandro Villagra, Eduardo M Sotomayor, Eva Sahakian, and Javier Pinilla-Ibarz

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Combination ART-Induced Oxidative/Nitrosative Stress, Neurogenic Inflammation and Cardiac Dysfunction in HIV-1 Transgenic (Tg) Rats: Protection by Mg., I Tong Mak, Joanna J Chmielinska, Christopher F Spurney, William B Weglicki, and Jay H Kramer

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DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer., Yunxiao Meng, Chi-Wei Chen, Mingo M H Yung, Wei Sun, Jing Sun, Zhuqing Li, Jing Li, Zongzhu Li, Wei Zhou, Stephanie S Liu, Annie N Y Cheung, Hextan Y S Ngan, John C Braisted, Yan Kai, Weiqun Peng, Alexandros Tzatsos, Yiliang Li, Zhijun Dai, Wei Zheng, David W Chan, and Wenge Zhu

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Are endocrine disrupting compounds environmental risk factors for autism spectrum disorder?, Amer Moosa, Henry Shu, Tewarit Sarachana, and Valerie W Hu