Submissions from 2020
Phenotypic subtyping and re-analysis of existing methylation data from autistic probands in simplex families reveal ASD subtype-associated differentially methylated genes and biological functions, Elizabeth C. Lee and Valerie W. Hu
HDAC10 Regulates Cancer Stem-Like Cell Properties in KRAS-Driven Lung Adenocarcinoma., Yixuan Li, Xiangyang Zhang, Shaoqi Zhu, Eden A. Dejene, Weiqun Peng, Antonia Sepulveda, and Edward Seto
Transcriptional dysregulation in developing trigeminal sensory neurons in the LgDel mouse model of DiGeorge 22q11.2 Deletion Syndrome., Thomas M. Maynard, Anelia Horvath, James Bernout, Beverly A. Karpinski, Andre L P Tavares, Ankita Shah, Qianqian Zheng, Liam Spurr, Jacqueline Olender, Sally A. Moody, Claire M. Fraser, Anthony-S LaMantia, and Norman H. Lee
Combining DNMT and HDAC6 inhibitors increases anti-tumor immune signaling and decreases tumor burden in ovarian cancer., Sara Moufarrij, Aneil Srivastava, Stephanie Gomez, Melissa Hadley, Erica Palmer, Paul Tran Austin, Sarah Chisholm, Kyle Roche, Angela Yu, Jing Li, Wenge Zhu, Micael Lopez-Acevedo, Alejandro Villagra, and Katherine B. Chiappinelli
Estimating the Allele-Specific Expression of SNVs From 10× Genomics Single-Cell RNA-Sequencing Data., Prashant N. M, Hongyu Liu, Pavlos Bousounis, Liam Spurr, Nawaf Alomran, Helen Ibeawuchi, Justin Sein, Dacian Reece-Stremtan, and Anelia Horvath
Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models, Satish Noonepalle, Sida Shen, Jakub Ptáček, Maurício T. Tavares, Guiping Zhang, Jan Stránský, Jiří Pavlíček, Glaucio M. Ferreira, Melissa Hadley, Guido Pelaez, Cyril Bařinka, Alan P. Kozikowski, and Alejandro Villagra
Testing the "Grandma Hypothesis": Characterizing Skin Microbiome Diversity as a Project-Based Learning Approach to Genomics., Marcos Pérez-Losada, Kelly M Crandall, and Keith A. Crandall
Thymosin α1 protects from CTLA-4 intestinal immunopathology., Giorgia Renga, Marina M Bellet, Marilena Pariano, Marco Gargaro, Claudia Stincardini, Fiorella D'Onofrio, Paolo Mosci, Stefano Brancorsini, Andrea Bartoli, Allan L. Goldstein, Enrico Garaci, Luigina Romani, and Claudio Costantini
GeTallele: A Method for Analysis of DNA and RNA Allele Frequency Distributions., Piotr Słowiński, Muzi Li, Paula Restrepo, Nawaf Alomran, Liam F. Spurr, Christian Miller, Krasimira Tsaneva-Atanasova, and Anelia Horvath
ReQTL: Identifying correlations between expressed SNVs and gene expression using RNA-sequencing data, Liam F. Spurr, Nawaf Alomran, Pavlos Bousounis, Dacian Reece-Stremtan, N. M. Prashant, Hongyu Liu, Piotr Słowiński, Muzi Li, Qianqian Zhang, Justin Sein, Gabriel Asher, Keith A. Crandall, Krasimira Tsaneva-Atanasova, and Anelia Horvath
Prenatal exposure to bisphenol A alters the transcriptome-interactome profiles of genes associated with Alzheimer's disease in the offspring hippocampus., Suporn Sukjamnong, Surangrat Thongkorn, Songphon Kanlayaprasit, Thanit Saeliw, Kanlayaphat Hussem, Watis Warayanon, Valerie W. Hu, Tewin Tencomnao, and Tewarit Sarachana
Evaluation of an angiotensin Type 1 receptor blocker on the reconsolidation of fear memory, Adam P. Swiercz, Laxmi Iyer, Zhe Yu, Allison Edwards, N. M. Prashant, Bryan N. Nguyen, Anelia Horvath, and Paul J. Marvar
Scanning window analysis of non-coding regions within normal-tumor whole-genome sequence samples., John Torcivia and Raja Mazumder
A Tale of Two Nineteenth-century Dutch Jewish Hospitals-One a Success, The Other a Failure., Jack Y. Vanderhoek
Liver prometastatic reaction: Stimulating factors and responsive cancer phenotypes., Fernando Vidal-Vanaclocha, Olatz Crende, Cira García de Durango, Alejandro Herreros-Pomares, Sandra López-Doménech, Álvaro González, Eva Ruiz-Casares, Thierry Vilboux, Riccardo Caruso, Hipólito Durán, Antonio Gil, Benedetto Ielpo, Fernando Lapuente, Yolanda Quijano, Emilio Vicente, Leticia Vidal-Lartitegui, and Eduardo M. Sotomayor
Genetic ablation of adipocyte PD-L1 reduces tumor growth but accentuates obesity-associated inflammation., Bogang Wu, Huai-Chin Chiang, Xiujie Sun, Bin Yuan, Payal Mitra, Yanfen Hu, Tyler J Curiel, and Rong Li
PPARγ inhibition boosts efficacy of PD-L1 Checkpoint Blockade Immunotherapy against Murine Melanoma in a sexually dimorphic manner., Bogang Wu, Xiujie Sun, Bin Yuan, Fei Ge, Harshita B Gupta, Huai-Chin Chiang, Jingwei Li, Yanfen Hu, Tyler J. Curiel, and Rong Li
The 3D genomic landscape of differential response to EGFR/HER2 inhibition in endocrine-resistant breast cancer cells., Yini Yang, Lavanya Choppavarapu, Kun Fang, Alireza S Naeini, Bakhtiyor Nosirov, Jingwei Li, Ke Yang, Zhijing He, Yufan Zhou, Rachel Schiff, Rong Li, Yanfen Hu, Junbai Wang, and Victor X Jin
GlyGen: Computational and Informatics Resources for Glycoscience., William S York, Raja Mazumder, Rene Ranzinger, Nathan Edwards, Robel Kahsay, Kiyoko F Aoki-Kinoshita, Matthew P Campbell, Richard D Cummings, Ten Feizi, Maria Martin, Darren A Natale, Nicolle H Packer, Robert J Woods, Gaurav Agarwal, Sena Arpinar, Sanath Bhat, Judith Blake, Leyla Jael Garcia Castro, Brian Fochtman, Jeffrey Gildersleeve, Radoslav Goldman, Xavier Holmes, Vinamra Jain, Sujeet Kulkarni, Rupali Mahadik, Akul Mehta, Reza Mousavi, Sandeep Nakarakommula, Rahi Navelkar, Nagarajan Pattabiraman, Michael J Pierce, Karen Ross, Preethi Vasudev, Jeet Vora, Tatiana Williamson, and Wenjin Zhang
Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression., Li Yu, Bin Zhang, Dinesh Deochand, Maria A Sacta, Maddalena Coppo, Yingli Shang, Ziyi Guo, Xiaomin Zeng, David A Rollins, Bowranigan Tharmalingam, Rong Li, Yurii Chinenov, Inez Rogatsky, and Xiaoyu Hu
Dysregulated metabolic pathways in age-related macular degeneration., Meng Zhang, Nisi Jiang, Yi Chu, Olga Postnikova, Rency Varghese, Anelia Horvath, Amrita K. Cheema, and Nady Golestaneh
A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing, Wen Wei Zhang, Subir Karmakar, Sreenivas Gannavaram, Ranadhir Dey, Patrick Lypaczewski, Nevien Ismail, Abid Siddiqui, Vahan Simonyan, Fabiano Oliveira, Iliano V. Coutinho-Abreu, Thiago DeSouza-Vieira, Claudio Meneses, James Oristian, Tiago D. Serafim, Abu Musa, Risa Nakamura, Noushin Saljoughian, Greta Volpedo, Monika Satoskar, Sanika Satoskar, Pradeep K. Dagur, J. Philip McCoy, Shaden Kamhawi, Jesus G. Valenzuela, Shinjiro Hamano, Abhay R. Satoskar, Greg Matlashewski, and Hira L. Nakhasi
Submissions from 2019
Codon and Codon-Pair Usage Tables (CoCoPUTs): Facilitating Genetic Variation Analyses and Recombinant Gene Design, Aikaterini Alexaki, Jacob Kames, David D. Holcomb, John Athey, Luis V. Santana-Quintero, Phuc Vihn Nguyen Lam, Nobuko Hamasaki-Katagiri, Ekaterina Osipova, Vahan Simonyan, Haim Bar, Anton A. Komar, and Chava Kimchi-Sarfaty
The GlySpace Alliance: towards a collaborative global glycoinformatics community., Kiyoko F. Aoki-Kinoshita, Frederique Lisacek, Raja Mazumder, William S. York, and Nicolle H. Packer
Immunoepigenetics Combination Therapies: An Overview of the Role of HDACs in Cancer Immunotherapy., Debarati Banik, Sara Moufarrij, and Alejandro Villagra
Identification and quantification of defective virus genomes in high throughput sequencing data using DVG-profiler, a novel post-sequence alignment processing algorithm, Trent J. Bosma, Konstantinos Karagiannis, Luis Santana-Quintero, Natalia Ilyushina, Tatiana Zagorodnyaya, Svetlana Petrovskaya, Majid Laassri, Raymond P. Donnelly, Steven Rubin, Vahan Simonyan, and Christian J. Sauder
Is the patient cured?, Harry B. Burke and Scott Kopetz
Prussian blue nanoparticle-based antigenicity and adjuvanticity trigger robust antitumor immune responses against neuroblastoma., Juliana Cano-Mejia, Michelle L Bookstaver, Elizabeth E Sweeney, Christopher M Jewell, and Rohan Fernandes
HDAC11 Regulates Type I Interferon Signaling through Defatty-Acylation of SHMT2., Ji Cao, Lei Sun, Pornpun Aramsangtienchai, Nicole A Spiegelman, Xiaoyu Zhang, Weishan Huang, Edward Seto, and Hening Lin
Stevioside inhibits experimental fibrosis by down-regulating profibrotic Smad pathways and blocking hepatic stellate cell activation., Sael Casas-Grajales, Diana Alvarez-Suarez, Erika Ramos-Tovar, Laura Dayana Buendía-Montaño, Karina Reyes-Gordillo, Javier Camacho, Víctor Tsutsumi, M Raj Lakshman, and Pablo Muriel
Antioxidant and immunomodulatory activity induced by stevioside in liver damage: In vivo, in vitro and in silico assays., Sael Casas-Grajales, Erika Ramos-Tovar, Esmeralda Chávez-Estrada, Diana Alvarez-Suarez, Erika Hernández-Aquino, Karina Reyes-Gordillo, Carlos M Cerda-García-Rojas, Javier Camacho, Víctor Tsutsumi, M Raj Lakshman, and Pablo Muriel
Rebaudioside A administration prevents experimental liver fibrosis: an in vivo and in vitro study of the mechanisms of action involved., Sael Casas-Grajales, Karina Reyes-Gordillo, Carlos M Cerda-García-Rojas, Víctor Tsutsumi, M Raj Lakshman, and Pablo Muriel
Investigation of somatic single nucleotide variations in human endogenous retrovirus elements and their potential association with cancer., Ting-Chia Chang, Santosh Goud, John Torcivia-Rodriguez, Yu Hu, Qing Pan, Robel Kahsay, Jonas Blomberg, and Raja Mazumder
PES1 is a critical component of telomerase assembly and regulates cellular senescence, Long Cheng, Bin Yuan, Sunyang Ying, Chang Niu, Hongxu Mai, Xin Guan, Xiaohui Yang, Yan Teng, Jing Lin, Junjian Huang, Rui Jin, Jun Wu, Bo Liu, Shaohong Chang, Enqun Wang, Chunxia Zhang, Ning Hou, Xuan Cheng, Danyang Xu, Xiao Yang, Shan Gao, and Qinong Ye
CRISPR Screening "Big Data" Informs Novel Therapeutic Solutions., Sitong Chen, Lin Yang, and Wei Li
BRCA1-associated R-loop affects transcription and differentiation in breast luminal epithelial cells, Huai Chin Chiang, Xiaowen Zhang, Jingwei Li, Xiayan Zhao, Jerry Chen, Howard T.H. Wang, Ismail Jatoi, Andrew Brenner, Yanfen Hu, and Rong Li
Substance P receptor blocker, aprepitant, inhibited cutaneous and other neurogenic inflammation side effects of the EGFR1-TKI, erlotinib., Joanna J. Chmielinska, Jay H. Kramer, I-Tong Mak, Christopher F. Spurney, and William B. Weglicki
A Reappraisal of Thymosin Alpha1 in Cancer Therapy., Claudio Costantini, Marina M. Bellet, Marilena Pariano, Giorgia Renga, Claudia Stincardini, Allan L. Goldstein, Enrico Garaci, and Luigina Romani
Engineering a Novel 3D Printed Vascularized Tissue Model for Investigating Breast Cancer Metastasis to Bone., Haitao Cui, Timothy Esworthy, Xuan Zhou, Sung Yun Hann, Robert I. Glazer, Rong Li, and Lijie Grace Zhang
Blockchain: An enabler for healthcare and life sciences transformation, F. Curbera, D. M. Dias, V. Simonyan, W. A. Yoon, and A. Casella
RNA m6A methyltransferase METTL3 regulates invasiveness of melanoma cells by matrix metallopeptidase 2., Ujwal Dahal, Le Kang, and Mamta Gupta
17-hydroxy wortmannin restores TRAIL's response by ameliorating increased beclin 1 level and autophagy function in TRAIL-resistant colon cancer cells., Sheng Dai, Shu Yang, Xin Hu, Wei Sun, Gregory Tawa, Wenge Zhu, Aaron D Schimmer, Chao He, Bingliang Fang, Hongbo Zhu, and Wei Zheng
Senescence-associated beta-galactosidase marker of cellular senescence, Manjari Dimri and Goberdhan P. Dimri
Mg-supplementation attenuated lipogenic and oxidative/nitrosative gene expression caused by Combination Antiretroviral Therapy (cART) in HIV-1-transgenic rats., Lama ElZohary, William B Weglicki, Joanna J Chmielinska, Jay H Kramer, and I Tong Mak
HDAC8 regulates a stress response pathway in melanoma to mediate escape from BRAF inhibitor therapy., Michael F Emmons, Fernanda Faião-Flores, Ritin Sharma, Ram Thapa, Jane L Messina, Jurgen C Becker, Dirk Schadendorf, Edward Seto, Vernon K Sondak, John M Koomen, Yian Ann Chen, Eric K Lau, Lixin Wan, Jonathan D Licht, and Keiran S M Smalley
History of the Discovery of Hepatitis A Virus., Stephen M Feinstone
Chronic administration of diethylnitrosamine to induce hepatocarcinogenesis and to evaluate its synergistic effect with other hepatotoxins in mice., Sergio Fuentes-Hernández, Brisa Rodope Alarcón-Sánchez, Dafne Guerrero-Escalera, Alexia Viridiana Montes-Aparicio, María Paulette Castro-Gil, Osiris Germán Idelfonso-García, Sandra Rosas-Madrigal, Diana Ivette Aparicio-Bautista, José Luis Pérez-Hernández, Karina Reyes-Gordillo, M Raj Lakshman, Verónica Rocío Vásquez-Garzón, Rafael Baltiérrez-Hoyos, Ma de Lourdes López-González, Adolfo Sierra-Santoyo, Saúl Villa-Treviño, Julio Isael Pérez-Carreón, and Jaime Arellanes-Robledo
Functional Analysis of HDACs in Tumorigenesis., Melissa Hadley, Satish Noonepalle, Debarati Banik, and Alejandro Villagra
Insights into the HIV Latency and the Role of Cytokines., Joseph Hokello, Adhikarimayum Lakhikumar Sharma, Manjari Dimri, and Mudit Tyagi
RIP sequencing in mantle cell lymphoma identifies functional long non-coding RNAs associated with translation machinery., Guangzhen Hu, Yuji Zhang, and Mamta Gupta
Sirtuin 6 Attenuates Kaposi's Sarcoma-Associated Herpesvirus Reactivation by Suppressing Ori-Lyt Activity and Expression of RTA., Min Hu, Najealicka Armstrong, Edward Seto, Wenwei Li, Fanxiu Zhu, Paul C Wang, and Qiyi Tang
ASD Phenotype-Genotype Associations in Concordant and Discordant Monozygotic and Dizygotic Twins Stratified by Severity of Autistic Traits., Valerie W. Hu, Christine A. Devlin, and Jessica J. Debski
Mental health comorbidities and cost/utilization outcomes in head and neck cancer patients, Diana D. Jeffery, Lcdr Art Ambrosio, Laura Hopkins, and Harry B. Burke
Heart Protection by Herb Formula BanXia BaiZhu TianMa Decoction in Spontaneously Hypertensive Rats., Jiaye Jiang, Dan Huang, Yuan Li, Zhongyuan Gan, Hanqing Li, Xindan Li, Ka Bian, and Yan Ke
Flotillins in the Intercalated Disc are Potential Modulators of Cardiac Excitability., Elise L Kessler, Leonie van Stuijvenberg, Joanne J A van Bavel, Joëlle van Bennekom, Anne Zwartsen, Mathilde R Rivaud, Aryan Vink, Igor R Efimov, Alex V Postma, J Peter van Tintelen, Carol A Remme, Marc A Vos, Antje Banning, Teun P de Boer, Ritva Tikkanen, and Toon A B van Veen
miCloud: A Plug-n-Play, Extensible, On-Premises Bioinformatics Cloud for Seamless Execution of Complex Next-Generation Sequencing Data Analysis Pipelines., Baekdoo Kim, Thahmina Ali, Changsu Dong, Carlos Lijeron, Raja Mazumder, Claudia Wultsch, and Konstantinos Krampis
Baseline human gut microbiota profile in healthy people and standard reporting template., Charles H. King, Hiral Desai, Allison C. Sylvetsky, Jonathan LoTempio, Shant Ayanyan, Jill Carrie, Keith A Crandall, Brian C Fochtman, Lusine Gasparyan, Naila Gulzar, Paul Howell, Najy Issa, Konstantinos Krampis, Lopa Mishra, Hiroki Morizono, Joseph R Pisegna, Shuyun Rao, Yao Ren, Vahan Simonyan, Krista Smith, Sharanjit VedBrat, Michael D Yao, and Raja Mazumder
Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells., Tessa Knox, Eva Sahakian, Debarati Banik, Melissa Hadley, Erica Palmer, Satish Noonepalle, Jennifer Kim, John Powers, Maria Gracia-Hernandez, Vasco Oliveira, Fengdong Cheng, Jie Chen, Cyril Barinka, Javier Pinilla-Ibarz, Norman H Lee, Alan Kozikowski, and Alejandro Villagra
Nonhomologous end joining key factor XLF enhances both 5-florouracil and oxaliplatin resistance in colorectal cancer., Zhuo Liu, Miao Yu, Bingyuan Fei, Jing Sun, and Dongxin Wang
Targeting MYC activity in double-hit lymphoma with MYC and BCL2 and/or BCL6 rearrangements with epigenetic bromodomain inhibitors, Weiping Li, Shiv K. Gupta, Weiguo Han, Ryan A. Kundson, Sara Nelson, Darlene Knutson, Patricia T. Greipp, Sherine F. Elsawa, Eduardo M. Sotomayor, and Mamta Gupta
ERK Regulates HIF1α-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer., Zhuqing Li, Wei Zhou, Yi Zhang, Wei Sun, Mingo M H Yung, Jing Sun, Jing Li, Chi-Wei Chen, Zongzhu Li, Yunxiao Meng, Jie Chai, Yuan Zhou, Stephanie S Liu, Annie N Y Cheung, Hextan Y S Ngan, David W Chan, Wei Zheng, and Wenge Zhu
Epigenetic therapy for ovarian cancer: Promise and progress, Sara Moufarrij, Monica Dandapani, Elisa Arthofer, Stephanie Gomez, Aneil Srivastava, Micael Lopez-Acevedo, Alejandro Villagra, and Katherine B. Chiappinelli
Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells, Nigora Mukhamedova, Anh Hoang, Dragana Dragoljevic, Larisa Dubrovsky, Tatiana Pushkarsky, Hann Low, Michael Ditiatkovski, Ying Fu, Ryunosuke Ohkawa, Peter J. Meikle, Anelia Horvath, Beda Brichacek, Yury I. Miller, Andrew Murphy, Michael Bukrinsky, and Dmitri Sviridov
The deubiquitylating enzyme USP15 regulates homologous recombination repair and cancer cell response to PARP inhibitors., Yihan Peng, Qingchao Liao, Wei Tan, Changmin Peng, Zhaohua Hu, Yali Chen, Zhuqing Li, Jing Li, Bei Zhen, Wenge Zhu, Xiangpan Li, Yi Yao, Qibin Song, Chengsheng Liu, Xiangdong Qi, Fuchu He, and Huadong Pei
Phenotypic Subgrouping and Multi-Omics Analyses Reveal Reduced Diazepam-Binding Inhibitor (DBI) Protein Levels in Autism Spectrum Disorder with Severe Language Impairment., Chatravee Pichitpunpong, Surangrat Thongkorn, Songphon Kanlayaprasit, Wasana Yuwattana, Waluga Plaingam, Siriporn Sangsuthum, Wan Mohd Aizat, Syarul Nataqain Baharum, Tewin Tencomnao, Valerie Wailin Hu, and Tewarit Sarachana
Emerging roles of histone modifications and HDACs in RNA splicing., Raneen Rahhal and Edward Seto
Thymosin β4 promotes autophagy and repair via HIF-1α stabilization in chronic granulomatous disease., Giorgia Renga, Vasilis Oikonomou, Silvia Moretti, Claudia Stincardini, Marina M Bellet, Marilena Pariano, Andrea Bartoli, Stefano Brancorsini, Paolo Mosci, Andrea Finocchi, Paolo Rossi, Claudio Costantini, Enrico Garaci, Allan L Goldstein, and Luigina Romani
Akt1 and Akt2 Isoforms Play Distinct Roles in Regulating the Development of Inflammation and Fibrosis Associated with Alcoholic Liver Disease., Karina Reyes-Gordillo, Ruchi Shah, Jaime Arellanes-Robledo, Ying Cheng, Joseph Ibrahim, and Pamela L Tuma
HDAC8 affects MGMT levels in glioblastoma cell lines via interaction with the proteasome receptor ADRM1, Irene Santos-Barriopedro, Yixuan Li, Sonali Bahl, and Edward Seto
Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models., Sida Shen, Melissa Hadley, Kseniya Ustinova, Jiri Pavlicek, Tessa Knox, Satish Noonepalle, Mauricio T. Tavares, Chad A. Zimprich, Guiping Zhang, Matthew B. Robers, Cyril Bařinka, Alan P. Kozikowski, and Alejandro Villagra
Microbiota of MR1 deficient mice confer resistance against Clostridium difficile infection, Ashley D. Smith, Elissa D. Foss, Irma Zhang, Jessica L. Hastie, Nicole P. Giordano, Lusine Gasparyan, Lam Phuc VinhNguyen, Alyxandria M. Schubert, Deepika Prasad, Hannah L. McMichael, Jinchun Sun, Richard D. Beger, Vahan Simonyan, Siobhán C. Cowley, and Paul E. Carlson
The Nuclear Export and Ubiquitin-Proteasome-Dependent Degradation of PPARγ Induced By Angiotensin II., Li Sun and Ka Bian
Sex Differences in the Effects of Prenatal Bisphenol A Exposure on Genes Associated with Autism Spectrum Disorder in the Hippocampus., Surangrat Thongkorn, Songphon Kanlayaprasit, Depicha Jindatip, Tewin Tencomnao, Valerie W Hu, and Tewarit Sarachana
PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy., Xinyi Tu, Bo Qin, Yong Zhang, Cheng Zhang, Mohamed Kahila, Somaira Nowsheen, Ping Yin, Jian Yuan, Huadong Pei, Hu Li, Jia Yu, Zhiwang Song, Qin Zhou, Fei Zhao, Jiaqi Liu, Chao Zhang, Haidong Dong, Robert W Mutter, and Zhenkun Lou
Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment., Rocio G Urdinguio, Virginia Lopez, Gustavo F Bayón, Rafael Diaz de la Guardia, Marta I Sierra, Estela García-Toraño, Raúl F Perez, María G García, Antonella Carella, Patricia C Pruneda, Cristina Prieto, Marija Dmitrijeva, Pablo Santamarina, Thalía Belmonte, Cristina Mangas, Elena Diaconu, Cecilia Ferrero, Juan Ramón Tejedor, Juan Luis Fernandez-Morera, Cristina Bravo, Clara Bueno, Alejandra Sanjuan-Pla, Ramon M Rodriguez, Beatriz Suarez-Alvarez, Carlos López-Larrea, Teresa Bernal, Enrique Colado, Milagros Balbín, Olivia García-Suarez, María Dolores Chiara, Inés Sáenz-de-Santa-María, Francisco Rodríguez, Ana Pando-Sandoval, Luis Rodrigo, Laura Santos, Ana Salas, Jesús Vallejo-Díaz, Ana C Carrera, Daniel Rico, Inmaculada Hernández-López, Amparo Vayá, José M Ricart, Edward Seto, Núria Sima-Teruel, Alejandro Vaquero, Luis Valledor, Maria Jesus Cañal, David Pisano, Osvaldo Graña-Castro, Tim Thomas, Anne K Voss, Pablo Menéndez, Ana Villar-Garea, Rainer Deutzmann, Agustín F Fernandez, and Mario F Fraga
Soluble ICAM 1 and VCAM 1 Blood Levels Alert on Subclinical Atherosclerosis in Non Smokers with Asymptomatic Metabolic Syndrome, Jose F. Varona, Roberto Ortiz-Regalón, Isabel Sánchez-Vera, Beatriz López-Melgar, Cira García-Durango, José María Castellano Vázquez, Jorge M. Solis, Leticia Fernández-Friera, and Fernando Vidal-Vanaclocha
MiR-30a regulates cancer cell response to chemotherapy through SNAI1/IRS1/AKT pathway., Tingting Wang, Gang Chen, Xuemei Ma, Yao Yang, Yali Chen, Yihan Peng, Zhigang Bai, Zhongtao Zhang, Huadong Pei, and Wei Guo
An efficient prototype method to identify and correct misspellings in clinical text., T Elizabeth Workman, Yijun Shao, Guy Divita, and Qing Zeng-Treitler
Identification of the PTEN-ARID4B-PI3K pathway reveals the dependency on ARID4B by PTEN-deficient prostate cancer, Ray-Chang Wu, In-Chi Young, Yu-Fang Chen, Sung-Ting Chuang, Antoun Toubaji, and Mei-Yi Wu
Metastasis suppressor NME1 promotes non-homologous end joining of DNA double-strand breaks., Renyu Xue, Yihan Peng, Baolin Han, Xiangpan Li, Yali Chen, and Huadong Pei
Novel reference genes in colorectal cancer identify a distinct subset of high stage tumors and their associated histologically normal colonic tissues, Lai Xu, Helen Luo, Rong Wang, Wells W. Wu, Je Nie Phue, Rong Fong Shen, Hartmut Juhl, Leihong Wu, Wei Lun Alterovitz, Vahan Simonyan, Lorraine Pelosof, and Amy S. Rosenberg
BRCA1 mutations attenuate super-enhancer function and chromatin looping in haploinsufficient human breast epithelial cells., Xiaowen Zhang, Yao Wang, Huai-Chin Chiang, Yuan-Pang Hsieh, Chang Lu, Ben Ho Park, Ismail Jatoi, Victor X Jin, Yanfen Hu, and Rong Li
Secretome profiling identifies neuron-derived neurotrophic factor as a tumor-suppressive factor in lung cancer., Ya Zhang, Xuefeng Wu, Yan Kai, Chia-Han Lee, Fengdong Cheng, Yixuan Li, Yongbao Zhuang, Javid Ghaemmaghami, Kun-Han Chuang, Zhuo Liu, Yunxiao Meng, Meghana Keswani, Nancy R. Gough, Xiaojun Wu, Wenge Zhu, Alexandros Tzatsos, Weiqun Peng, Edward Seto, Eduardo M. Sotomayor, and Xiaoyan Zheng
The Cdk2-c-Myc-miR-571 Axis Regulates DNA Replication and Genomic Stability by Targeting Geminin., Yi Zhang, Zhuqing Li, Qiang Hao, Wei Tan, Jing Sun, Jing Li, Chi-Wei Chen, Zongzhu Li, Yunxiao Meng, Yuan Zhou, Zhiyong Han, Huadong Pei, Melvin L DePamphilis, and Wenge Zhu
Submissions from 2018
Ethanol targets nucleoredoxin/dishevelled interactions and stimulates phosphatidylinositol 4-phosphate production in vivo and in vitro., Jaime Arellanes-Robledo, Karina Reyes-Gordillo, Joseph Ibrahim, Leslie Leckey, Ruchi Shah, and M Raj Lakshman
HDAC11 suppresses the thermogenic program of adipose tissue via BRD2., Rushita A. Bagchi, Bradley S. Ferguson, Matthew S. Stratton, Tianjing Hu, Maria A. Cavasin, Lei Sun, Ying-Hsi Lin, Dianxin Liu, Pilar Londono, Kunhua Song, Maria F. Pino, Lauren M. Sparks, Steven R. Smith, Philipp E. Scherer, Sheila Collins, Edward Seto, and Timothy A. McKinsey
Challenges and Opportunities in Social Epigenomics and Cancer., Krishna Banaudha, Vineet Kumar, and Mukesh Verma
Stevioside Inhibits Experimental Fibrosis by Downregulating Profibrotic Smad Pathways and Blocking HSC Activation., Sael Casas-Grajales, Diana Alvarez-Suarez, Erika Ramos-Tovar, Laura Dayana Buendía-Montaño, Karina Reyes-Gordillo, Javier Camacho, Víctor Tsutsumi, M Raj Lakshman, and Pablo Muriel
DHS (trans-4,4'-dihydroxystilbene) Suppresses DNA Replication and Tumor Growth by Inhibiting RRM2 (ribonucleotide Reductase Regulatory Subunit M2)., Chi-Wei Chen, Yongming Li, Shuya Hu, Wei Zhou, Yunxiao Meng, Zongzhu Li, Yi Zhang, Jing Sun, Zhou Bo, Melvin L DePamphilis, Yun Yen, Zhiyong Han, and Wenge Zhu
Gene-Specific Genetic Complementation between Brca1 and Cobra1 During Mouse Mammary Gland Development., Huai-Chin Chiang, Xiaowen Zhang, Xiayan Zhao, Chi Zhang, Jerry Chen, Paula Garza, Sabrina Smith, Thomas Ludwig, Richard J Baer, Rong Li, and Yanfen Hu
Loss and gain of N-linked glycosylation sequons due to single-nucleotide variation in cancer., Yu Fan, Yu Hu, Cheng Yan, Radoslav Goldman, Yang Pan, Raja Mazumder, and Hayley M Dingerdissen
Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein BMI1 in breast cancer cells., Joseph E Gergely, Armond E Dorsey, Goberdhan P Dimri, and Manjari Dimri
DEXTER: Disease-Expression Relation Extraction from Text., Samir Gupta, Hayley Dingerdissen, Karen E Ross, Yu Hu, Cathy H Wu, Raja Mazumder, and K Vijay-Shanker
Prognostic and Therapeutic Significance of Phosphorylated STAT3 and Protein Tyrosine Phosphatase-6 in Peripheral-T Cell Lymphoma., Jing Jing Han, Megan O'byrne, Mary J Stenson, Matthew J Maurer, Linda E Wellik, Andrew L Feldman, Ellen D McPhail, Thomas E Witzig, and Mamta Gupta
Elevated GLI3 expression in germinal center diffuse large B cell lymphoma., Weiguo Han, Gabriela Ibarra, Mamta Gupta, Yanbin Yin, and Sherine F Elsawa
The Comparative Associations of Ultrasound and Computed Tomography Estimates of Muscle Quality with Physical Performance and Metabolic Parameters in Older Men., Michael O Harris-Love, Nilo A Avila, Bernadette Adams, June Zhou, Bryant Seamon, Catheeja Ismail, Syed H Zaidi, Courtney A Kassner, Frank Liu, and Marc R Blackman
MicroRNA-34 family in breast cancer: from research to therapeutic potential., Saber Imani, Ray-Chang Wu, and Junjiang Fu
Total Flavonoids from Radix Glycyrrhiza Exert Anti-Inflammatory and Antitumorigenic Effects by Inactivating iNOS Signaling Pathways., Yi-Xin Jiang, Yang-Yi Dai, Yi-Feng Pan, Xi-Min Wu, Yue Yang, Ka Bian, and Dan-Dan Zhang
RGN-259 (thymosin β4) improves clinically important dry eye efficacies in comparison with prescription drugs in a dry eye model., Chae Eun Kim, Hynda K Kleinman, Gabriel Sosne, George W Ousler, Kyeongsoon Kim, Sinwook Kang, and Jaewook Yang