Submissions from 2024
Deep skin fibroblast-mediated macrophage recruitment supports acute wound healing, Veronica M. Amuso, MaryEllen R. Haas, Paula O. Cooper, Ranojoy Chatterjee, Sana Hafiz, Shatha Salameh, Chiraag Gohel, Miguel F. Mazumder, Violet Josephson, Khatereh Khorsandi, Anelia Horvath, Ali Rahnavard, and Brett A. Shook
R-loop functions in Brca1-associated mammary tumorigenesis, Huai-Chin Chiang, Leilei Qi, Payal Mitra, Yimeng Huang, Yanfen Hu, and Rong Li
G-protein-coupled receptor 84 regulates acute inflammation in normal and diabetic skin wounds, Paula O. Cooper, Sarah S. Kleb, Satish K. Noonepalle, Veronica M. Amuso, Rohan Varshney, Michael C. Rudolph, Tanvir K. Dhaliwal, Darlene V. Nguyen, Miguel F. Mazumder, Najuma S. Babirye, Ruchi Gupta, Bao-Ngoc Nguyen, and Brett A. Shook
G-protein-coupled receptor 84 regulates acute inflammation in normal and diabetic skin wounds, Paula O. Cooper, Sarah S. Kleb, Satish K. Noonepalle, Veronica M. Amuso, Rohan Varshney, Michael C. Rudolph, Tanvir K. Dhaliwal, Darlene V. Nguyen, Miguel F. Mazumder, Najuma S. Babirye, Ruchi Gupta, Bao-Ngoc Nguyen, and Brett A. Shook
The original colorimetric method to detect cellular senescence, Manjari Dimri and Goberdhan P. Dimri
Systematic pan-cancer analysis reveals OGT and OGA as potential biomarkers for tumor microenvironment and therapeutic responses, Chunyan Hou, Ci Wu, Wenge Zhu, Huadong Pei, and Junfeng Ma
Sex-specific impacts of prenatal bisphenol A exposure on genes associated with cortical development, social behaviors, and autism in the offspring's prefrontal cortex, Songphon Kanlayaprasit, Thanit Saeliw, Surangrat Thongkorn, Pawinee Panjabud, Kasidit Kasitipradit, Pattanachat Lertpeerapan, Kwanjira Songsritaya, Wasana Yuwattana, Thanawin Jantheang, Depicha Jindatip, Valerie W. Hu, Takako Kikkawa, Noriko Osumi, and Tewarit Sarachana
Communicating computational workflows in a regulatory environment, Jonathon G. Keeney, Naila Gulzar, Jack B. Baker, Ondrej Klempir, Geoffrey D. Hannigan, Danny A. Bitton, Julia M. Maritz, Charles H. King, Janisha A. Patel, Paul Duncan, and Raja Mazumder
Communicating computational workflows in a regulatory environment, Jonathon G. Keeney, Naila Gulzar, Jack B. Baker, Ondrej Klempir, Geoffrey D. Hannigan, Danny A. Bitton, Julia M. Maritz, Charles H. King, Janisha A. Patel, Paul Duncan, and Raja Mazumder
HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression, Hongbo Ling, Yixuan Li, Changmin Peng, Shengyu Yang, and Edward Seto
Functional implications of glycans and their curation: insights from the workshop held at the 16th Annual International Biocuration Conference in Padua, Italy, Karina Martinez, Jon Agirre, Yukie Akune, Kiyoko F. Aoki-Kinoshita, Cecilia Arighi, Kristian B. Axelsen, Evan Bolton, Emily Bordeleau, Nathan J. Edwards, Elisa Fadda, Ten Feizi, Catherine Hayes, Callum M. Ives, Hiren J. Joshi, Khakurel Krishna Prasad, Sofia Kossida, Frederique Lisacek, Yan Liu, Thomas Lütteke, Junfeng Ma, Adnan Malik, Maria Martin, Akul Y. Mehta, Sriram Neelamegham, Kalpana Panneerselvam, René Ranzinger, Sylvie Ricard-Blum, Gaoussou Sanou, Vijay Shanker, Paul D. Thomas, Michael Tiemeyer, and James Urban
Biological basis of extensive pleiotropy between blood traits and cancer risk, Miguel Angel Pardo-Cea, Xavier Farré, Anna Esteve, Joanna Palade, Roderic Espín, Francesca Mateo, Eric Alsop, Marc Alorda, Natalia Blay, Alexandra Baiges, Arzoo Shabbir, Francesc Comellas, Antonio Gómez, Montserrat Arnan, Alex Teulé, Monica Salinas, Laura Berrocal, Joan Brunet, Paula Rofes, Conxi Lázaro, Miquel Conesa, Juan Jose Rojas, Lars Velten, Wojciech Fendler, Urszula Smyczynska, Dipanjan Chowdhury, Yong Zeng, Housheng Hansen He, Rong Li, Kendall Van Keuren-Jensen, Rafael de Cid, and Miquel Angel Pujana
Aquilaria crassna Extract Exerts Neuroprotective Effect against Benzo[a]pyrene-Induced Toxicity in Human SH-SY5Y Cells: An RNA-Seq-Based Transcriptome Analysis, Nattaporn Pattarachotanant, Suporn Sukjamnong, Panthakarn Rangsinth, Kamonwan Chaikhong, Chanin Sillapachaiyaporn, George Pak-Heng Leung, Valerie W. Hu, Tewarit Sarachana, Siriporn Chuchawankul, Tewin Tencomnao, and Anchalee Prasansuklab
Social norms, vaccine confidence, and interpersonal communication as predictors of vaccination intentions: Findings from slum areas in Varanasi, India, Rajiv N. Rimal, Rohini Ganjoo, Amelia Jamison, Manoj Parida, and Saraniya Tharmarajah
Investigation of chimeric transcripts derived from LINE-1 and Alu retrotransposons in cerebellar tissues of individuals with autism spectrum disorder (ASD), Thanit Saeliw, Songphon Kanlayaprasit, Surangrat Thongkorn, Kwanjira Songsritaya, Bumpenporn Sanannam, Depicha Jindatip, Valerie W. Hu, and Tewarit Sarachana
Landscape Analysis of Neurodevelopmental Comorbidities in Newborn Screening Conditions: Challenges and Opportunities, Zohreh Talebizadeh, Valerie Hu, Monir Shababi, and Amy Brower
O-GlcNAcylation of MITF regulates its activity and CDK4/6 inhibitor resistance in breast cancer, Yi Zhang, Shuyan Zhou, Yan Kai, Ya-Qin Zhang, Changmin Peng, Zhuqing Li, Muhammad Jameel Mughal, Belmar Julie, Xiaoyan Zheng, Junfeng Ma, Cynthia X. Ma, Min Shen, Matthew D. Hall, Shunqiang Li, and Wenge Zhu
Submissions from 2023
COVID-19 and beyond: Reassessing the role of thymosin alpha1 in lung infections, Marina M. Bellet, Giorgia Renga, Marilena Pariano, Claudia Stincardini, Fiorella D'Onofrio, Allan L. Goldstein, Enrico Garaci, Luigina Romani, and Claudio Costantini
Developing a definition of immune exclusion in cancer: results of a modified Delphi workshop, Guy Travis Clifton, Mace Rothenberg, Paolo Antonio Ascierto, Glenn Begley, Michael Cecchini, Joseph Paul Eder, Francois Ghiringhelli, Antoine Italiano, Marina Kochetkova, Rong Li, Fatima Mechta-Grigoriou, Sara I. Pai, Paolo Provenzano, Ellen Puré, Antoni Ribas, Kurt A. Schalper, and Wolf Herve Fridman
HDAC8-mediated inhibition of EP300 drives a transcriptional state that increases melanoma brain metastasis, Michael F. Emmons, Richard L. Bennett, Alberto Riva, Kanchan Gupta, Larissa Anastasio Carvalho, Chao Zhang, Robert Macaulay, Daphne Dupéré-Richér, Bin Fang, Edward Seto, John M. Koomen, Jiannong Li, Y Ann Chen, Peter A. Forsyth, Jonathan D. Licht, and Keiran S. Smalley
Embryonic stem cell factor FOXD3 (Genesis) defects in gastrointestinal stromal tumors, Fabio R. Faucz, Anelia D. Horvath, Guillaume Assié, Madson Q. Almeida, Eva Szarek, Sosipatros Boikos, Anna Angelousi, Isaac Levy, Andrea G. Maria, Ajay Chitnis, Cristina R. Antonescu, Rainer Claus, Jérôme Bertherat, Christoph Plass, Charis Eng, and Constantine A. Stratakis
Embryonic stem cell factor FOXD3 (Genesis) defects in gastrointestinal stromal tumors, Fabio R. Faucz, Anelia D. Horvath, Guillaume Assié, Madson Q. Almeida, Eva Szarek, Sosipatros Boikos, Anna Angelousi, Isaac Levy, Andrea G. Maria, Ajay Chitnis, Cristina R. Antonescu, Rainer Claus, Jérôme Bertherat, Christoph Plass, Charis Eng, and Constantine A. Stratakis
Thymosins in health & disease, the sixth international symposium, Enrico Garaci and Allan L. Goldstein
Trapoxin A Analogue as a Selective Nanomolar Inhibitor of HDAC11, Thanh Tu Ho, Changmin Peng, Edward Seto, and Hening Lin
Blockade of CCR1 induces a phenotypic shift in macrophages and triggers a favorable antilymphoma activity, Kang Le, Jing Sun, Javid Ghaemmaghami, Mitchell R. Smith, W K. Ip, Tycel Jovelle Phillips, and Mamta Gupta
Dependence of peripheral T-cell lymphoma on constitutively activated JAK3: Implication for JAK3 inhibition as a therapeutic approach, Kang Le, Jordan Vollenweider, JingJing Han, Nicholas Staudinger, Mary Stenson, Lara Bayraktar, Linda E. Wellik, Matthew J. Maurer, Ellen D. McPhail, Thomas E. Witzig, and Mamta Gupta
Worldwide Glycoscience Informatics Infrastructure: The GlySpace Alliance, Frederique Lisacek, Michael Tiemeyer, Raja Mazumder, and Kiyoko F. Aoki-Kinoshita
A highly selective humanized DDR1 mAb reverses immune exclusion by disrupting collagen fiber alignment in breast cancer, Junquan Liu, Huai-Chin Chiang, Wei Xiong, Victor Laurent, Samuel C. Griffiths, Jasmin Dülfer, Hui Deng, Xiujie Sun, Y Whitney Yin, Wenliang Li, Laurent P. Audoly, Zhiqiang An, Thomas Schürpf, Rong Li, and Ningyan Zhang
An Essential Signaling Function of Cytoplasmic NELFB is Independent of RNA Polymerase II Pausing, Haihui Pan, Xiaolong Cheng, Pedro Felipe Rodríguez, Xiaowen Zhang, Inhee Chung, Victor X. Jin, Wei Li, Yanfen Hu, and Rong Li
Transcriptomic analysis of glutamate-induced HT22 neurotoxicity as a model for screening anti-Alzheimer's drugs, Anchalee Prasansuklab, Suporn Sukjamnong, Atsadang Theerasri, Valerie W. Hu, Tewarit Sarachana, and Tewin Tencomnao
Integration of fluorescence in situ hybridization and chromosome-length genome assemblies revealed synteny map for guinea pig, naked mole-rat, and human, Svetlana A. Romanenko, Sergei F. Kliver, Natalia A. Serdyukova, Polina L. Perelman, Vladimir A. Trifonov, Andrei Seluanov, Vera Gorbunova, Jorge Azpurua, Jorge C. Pereira, Malcolm A. Ferguson-Smith, and Alexander S. Graphodatsky
Nitric oxide-releasing gel accelerates healing in a diabetic murine splinted excisional wound model, Dharshan Sivaraj, Chikage Noishiki, Nina Kosaric, Harriet Kiwanuka, Hudson C. Kussie, Dominic Henn, Katharina S. Fischer, Artem A. Trotsyuk, Autumn H. Greco, Britta A. Kuehlmann, Filiberto Quintero, Melissa C. Leeolou, Maia B. Granoski, Andrew C. Hostler, William W. Hahn, Michael Januszyk, Ferid Murad, Kellen Chen, and Geoffrey C. Gurtner
Engineered tumor-specific T cells using immunostimulatory photothermal nanoparticles, Elizabeth E. Sweeney, Palak Sekhri, Deepti Telaraja, Jie Chen, Samantha J. Chin, Katherine B. Chiappinelli, Carlos E. Sanchez, Catherine M. Bollard, C Russell Cruz, and Rohan Fernandes
Investigation of autism-related transcription factors underlying sex differences in the effects of bisphenol A on transcriptome profiles and synaptogenesis in the offspring hippocampus, Surangrat Thongkorn, Songphon Kanlayaprasit, Kasidit Kasitipradit, Pattanachat Lertpeerapan, Pawinee Panjabud, Valerie W. Hu, Depicha Jindatip, and Tewarit Sarachana
Jewish Hospitals in 20th Century Amsterdam: A Tale of Growth, Change, and Decline, Jack Y. Vanderhoek
The Joles Jewish Hospital: A Short-lived Dutch Small City Hospital With an Unusual Resurrection, Jack Y. Vanderhoek and Dick van de Kamp
BRCA1 deficiency in mature CD8 T lymphocytes impairs antitumor immunity, Bogang Wu, Leilei Qi, Huai-Chin Chiang, Haihui Pan, Xiaowen Zhang, Alexandra Greenbaum, Elizabeth Stark, Li-Ju Wang, Yidong Chen, Bassem R. Haddad, Dionyssia Clagett, Claudine Isaacs, Richard Elledge, Anelia Horvath, Yanfen Hu, and Rong Li
Multi-omics approaches to studying gastrointestinal microbiome in the context of precision medicine and machine learning, Jingyue Wu, Stephanie S. Singleton, Urnisha Bhuiyan, Lori Krammer, and Raja Mazumder
Soluble Guanylate Cyclase β1 Subunit Represses Human Glioblastoma Growth, Haijie Xiao, Haifeng Zhu, Oliver Bögler, Fabiola Zakia Mónica, Alexander Y. Kots, Ferid Murad, and Ka Bian
O-GlcNAcylation of MITF regulates its activity and CDK4/6 inhibitor resistance in breast cancer, Wenge Zhu, Y I. Zhang, Shuyan Zhou, Yan Kai, Ya-Qin Zhang, Changmin Peng, Zhuqing Li, Muhammad Mughal, Junfeng Ma, Shunqiang Li, Cynthia Ma, Min Shen, and Matthew Hall
Submissions from 2022
Reversible lysine fatty acylation of an anchoring protein mediates adipocyte adrenergic signaling., Rushita A Bagchi, Emma L Robinson, Tianjing Hu, Ji Cao, Jun Young Hong, Charles A Tharp, Hanan Qasim, Kathleen M Gavin, Julie Pires da Silva, Jennifer L Major, Bradley K McConnell, Edward Seto, Hening Lin, and Timothy A McKinsey
Higher levels of Bifidobacteria and tumor necrosis factor in children with drug-resistant epilepsy are associated with anti-seizure response to the ketogenic diet, Maria Dahlin, Stephanie S. Singleton, John A. David, Atin Basuchoudhary, Ronny Wickström, Raja Mazumder, and Stefanie Prast-Nielsen
Higher levels of Bifidobacteria and tumor necrosis factor in children with drug-resistant epilepsy are associated with anti-seizure response to the ketogenic diet, Maria Dahlin, Stephanie S. Singleton, John A. David, Atin Basuchoudhary, Ronny Wickström, Raja Mazumder, and Stefanie Prast-Nielsen
Cardiomyocyte-specific regression of nitrosative stress-mediated S-Nitrosylation of IKKγ alleviates pathological cardiac hypertrophy, Ratul Datta Chaudhuri, Ritwik Datta, Santanu Rana, Abhik Kar, Phuc Vinh Nguyen Lam, Raja Mazumder, Sujata Mohanty, and Sagartirtha Sarkar
SCExecute: custom cell barcode-stratified analyses of scRNA-seq data, Nathan Edwards, Christian Dillard, Prashant N M, Hongyu Liu, Mia Yang, Evgenia Ulianova, and Anelia Horvath
BRCA1 and Breast Cancer: Molecular Mechanisms and Therapeutic Strategies, Xiaoyu Fu, Wei Tan, Qibin Song, Huadong Pei, and Juanjuan Li
An Fluorescence Resonance Energy Transfer-Based Imaging Platform for Targeted Drug Discovery and Cancer Therapy, Shigao Huang, Cheng Jiang, Muhammad Jameel Mughal, Guanyu Wang, and Fuqiang Xing
Selective disruption of trigeminal sensory neurogenesis and differentiation in a mouse model of 22q11.2 deletion syndrome., Beverly A. Karpinski, Thomas M Maynard, Corey A. Bryan, Gelila Yitsege, Anelia Horvath, Norman H. Lee, Sally A. Moody, and Anthony-Samuel LaMantia
Communicating regulatory high-throughput sequencing data using BioCompute Objects, Charles Hadley King, Jonathon Keeney, Nuria Guimera, Souvik Das, Michiel Weber, Brian Fochtman, Mark O. Walderhaug, Sneh Talwar, Janisha A. Patel, Raja Mazumder, and Eric F. Donaldson
Prepared for special issue on thymosins Thymosin β4 and the anti-fibrotic switch, Hynda K. Kleinman, Veronika Kulik, and Allan L. Goldstein
Tumor-intrinsic PD-L1 promotes DNA repair in distinct cancers and suppresses PARP inhibitor-induced synthetic lethality, Anand V. Kornepati, Jacob T. Boyd, Clare E. Murray, Julia Saifetyarova, Bárbara de la Peña Avalos, Cody M. Rogers, Haiyan Bai, Alvaro S. Padron, Yiji Liao, Carlos Ontiveros, Robert S. Svatek, Robert Hromas, Rong Li, Yanfen Hu, Jose R. Conejo-Garcia, Ratna K. Vadlamudi, Weixing Zhao, Eloise Dray, Patrick Sung, and Tyler J. Curiel
Histopathological growth patterns of liver metastasis: updated consensus guidelines for pattern scoring, perspectives and recent mechanistic insights, Emily Latacz, Diederik Höppener, Ali Bohlok, Sophia Leduc, Sébastien Tabariès, Carlos Fernández Moro, Claire Lugassy, Hanna Nyström, Béla Bozóky, Giuseppe Floris, Natalie Geyer, Pnina Brodt, Laura Llado, Laura Van Mileghem, Maxim De Schepper, Ali W. Majeed, Anthoula Lazaris, Piet Dirix, Qianni Zhang, Stéphanie K. Petrillo, Sophie Vankerckhove, Ines Joye, Yannick Meyer, Alexander Gregorieff, Nuria Ruiz Roig, Fernando Vidal-Vanaclocha, Larsimont Denis, Rui Caetano Oliveira, Peter Metrakos, Dirk J. Grünhagen, Iris D. Nagtegaal, and David G. Mollevi
Raf Kinase Inhibitory Protein regulates the cAMP-dependent protein kinase signaling pathway through a positive feedback loop, Jiyoung Lee, Cristina Olivieri, Colin Ong, Larry R. Masterson, Suzana Gomes, Bok-Soon Lee, Florian Schaefer, Kristina Lorenz, Gianluigi Veglia, and Marsha Rich Rosner
Modeling and integration of N-glycan biomarkers in a comprehensive biomarker data model, Daniel F. Lyman, Amanda Bell, Alyson Black, Hayley Dingerdissen, Edmund Cauley, Nikhita Gogate, David Liu, Ashia Joseph, Robel Kahsay, Daniel J. Crichton, Anand Mehta, and Raja Mazumder
Modeling and integration of N-glycan biomarkers in a comprehensive biomarker data model, Daniel F. Lyman, Amanda Bell, Alyson Black, Hayley Dingerdissen, Edmund Cauley, Nikhita Gogate, David Liu, Ashia Joseph, Robel Kahsay, Daniel J. Crichton, Anand Mehta, and Raja Mazumder
Elevated exposures to persistent endocrine disrupting compounds impact the sperm methylome in regions associated with autism spectrum disorder, Angela G. Maggio, Henry T. Shu, Benjamin I. Laufer, Chongfeng Bi, Yinglei Lai, Janine M. LaSalle, and Valerie W. Hu
Modification of BRCA1-associated breast cancer risk by HMMR overexpression, Francesca Mateo, Zhengcheng He, Lin Mei, Gorka Ruiz de Garibay, Carmen Herranz, Nadia García, Amanda Lorentzian, Alexandra Baiges, Eline Blommaert, Antonio Gómez, Oriol Mirallas, Anna Garrido-Utrilla, Luis Palomero, Roderic Espín, Ana I. Extremera, M Teresa Soler-Monsó, Anna Petit, Rong Li, Joan Brunet, Ke Chen, Susanna Tan, Connie J. Eaves, Curtis McCloskey, Razq Hakem, Rama Khokha, Philipp F. Lange, Conxi Lázaro, Christopher A. Maxwell, and Miquel Angel Pujana
Epithelial NELF guards intestinal barrier function to ameliorate colitis by maintaining junctional integrity, Jiayao Ou, Xiaoxing Guan, Jiali Wang, Tianjiao Wang, Bin Zhang, Rong Li, Huji Xu, Xiaoyu Hu, and Xue-Kun Guo
A Heme-Binding Transcription Factor BACH1 Regulates Lactate Catabolism Suggesting a Combined Therapy for Triple-Negative Breast Cancer, Joselyn Padilla, Bok-Soon Lee, Karen Zhai, Bethany Rentz, Tia Bobo, Norca Maritza Dowling, and Jiyoung Lee
LINE-1 and Alu methylation signatures in autism spectrum disorder and their associations with the expression of autism-related genes, Thanit Saeliw, Tiravut Permpoon, Nutta Iadsee, Tewin Tencomnao, Valerie W. Hu, Tewarit Sarachana, Daniel Green, and Chanachai Sae-Lee
RNA polymerase II pausing factor NELF in CD8 T cells promotes antitumor immunity, Bogang Wu, Xiaowen Zhang, Huai-Chin Chiang, Haihui Pan, Bin Yuan, Payal Mitra, Leilei Qi, Hayk Simonyan, Colin N. Young, Eric Yvon, Yanfen Hu, Nu Zhang, and Rong Li
And-1 coordinates with the FANCM complex to regulate Fanconi Anemia signaling and cisplatin resistance, Yi Zhang, Jing Li, Yuan Zhou, Zhuqing Li, Changmin Peng, Huadong Pei, and Wenge Zhu
And-1 O-GlcNAcylation regulates homologous recombination repair and radioresistance in colorectal cancer, Yuan Zhou, Yi Zhang, Changmin Peng, Zhuqing Li, Huadong Pei, Haiping Pei, and Wenge Zhu
Submissions from 2021
Chemosensitization of HT29 and HT29-5FU Cell Lines by a Combination of a Multi-Tyrosine Kinase Inhibitor and 5FU Downregulates ABCC1 and Inhibits PIK3CA in Light of Their Importance in Saudi Colorectal Cancer., Ashraf N Abdalla, Waleed H Malki, Amal Qattan, Imran Shahid, Mohammad Akbar Hossain, and Muhammad Ahmed
Enhancing Therapeutic Approaches for Melanoma Patients Targeting Epigenetic Modifiers., Maria Gracia-Hernandez, Zuleima Munoz, and Alejandro Villagra
Recovery of altered diabetic myofibroblast heterogeneity and gene expression associated with CD301B+ macrophages, MaryEllen R. Haas, Darlene V. Nguyen, and Brett A. Shook
Bromodomain Epigenetic Protein Promotes Metastatic Potential in Melanoma Cells through Increased Invasiveness and Decreased Macrophage-Mediated Phagocytosis., Kang Le, Hector Matar, and Mamta Gupta
Mantle cell lymphoma polarizes tumor-associated macrophages into M2-like macrophages, which in turn promote tumorigenesis, Kang Le, Jing Sun, Hunain Khawaja, Maho Shibata, Sanjay B. Maggirwar, Mitchell R. Smith, and Mamta Gupta
JAK2 activation promotes tumorigenesis in ALK-negative anaplastic large cell lymphoma via regulating oncogenic STAT1-PVT1 lncRNA axis, Kang Le, Linda E. Wellik, Matthew J. Maurer, Ellen D. McPhail, Thomas E. Witzig, and Mamta Gupta
Phase I Study of Entinostat in Combination with Enzalutamide for Treatment of Patients with Metastatic Castration-Resistant Prostate Cancer., Jianqing Lin, Jacob Elkon, Brittany Ricart, Erica Palmer, Christian Zevallos-Delgado, Satish Noonepalle, Brooke Burgess, Robert Siegel, Yan Ma, and Alejandro Villagra
Enhancing the interoperability of glycan data flow between ChEBI, PubChem, and GlyGen., Rahi Navelkar, Gareth Owen, Venkatesh Mutherkrishnan, Paul Thiessen, Tiejun Cheng, Evan Bolerlton, Nathan Edwards, Michael Tiemeyer, Matthew P Campbell, Maria Martin, Jeet Vora, Robel Kahsay, and Raja Mazumder
Yeast Bromodomain Factor 1 and Its Human Homolog TAF1 Play Conserved Roles in Promoting Homologous Recombination., Haoyang Peng, Simin Zhang, Yihan Peng, Shuangyi Zhu, Xin Zhao, Xiaocong Zhao, Shuangshuang Yang, Guangxue Liu, Yang Dong, Xiaoli Gan, Qing Li, Xinghua Zhang, Huadong Pei, and Xuefeng Chen
DNA alkylation lesion repair: outcomes and implications in cancer chemotherapy., Yihan Peng and Huadong Pei
Clinical Identification of Dysregulated Circulating microRNAs and Their Implication in Drug Response in Triple Negative Breast Cancer (TNBC) by Target Gene Network and Meta-Analysis., Amal Qattan, Taher Al-Tweigeri, Wafa Alkhayal, Kausar Suleman, Asma Tulbah, and Suad Amer
Sex differences in the effects of prenatal bisphenol A exposure on autism-related genes and their relationships with the hippocampus functions., Surangrat Thongkorn, Songphon Kanlayaprasit, Pawinee Panjabud, Thanit Saeliw, Thanawin Jantheang, Kasidit Kasitipradit, Suthathip Sarobol, Depicha Jindatip, Valerie W. Hu, Tewin Tencomnao, Takako Kikkawa, Tatsuya Sato, Noriko Osumi, and Tewarit Sarachana
The human O-GlcNAcome database and meta-analysis., Eugenia Wulff-Fuentes, Rex R Berendt, Logan Massman, Laura Danner, Florian Malard, Jeet Vora, Robel Kahsay, and Stephanie Olivier-Van Stichelen
Estrogen receptor beta signaling in CD8 + T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch, Bin Yuan, Curtis A Clark, Bogang Wu, Jing Yang, Justin M Drerup, Tianbao Li, Victor X Jin, Yanfen Hu, Tyler J Curiel, and Rong Li
A Phosphotyrosine Switch in Estrogen Receptor β Is Required for Mouse Ovarian Function., Bin Yuan, Jing Yang, Louis Dubeau, Yanfen Hu, and Rong Li
Submissions from 2020
Significance of Targeting VEGFR-2 and Cyclin D1 in Luminal-A Breast Cancer., Ashraf N Abdalla, Amal Qattan, Waleed H Malki, Imran Shahid, Mohammad Akbar Hossain, and Muhammad Ahmed
Nucleoredoxin interaction with flightless-I/actin complex is differentially altered in alcoholic liver disease., Brisa Rodope Alarcón-Sánchez, Dafne Guerrero-Escalera, Sandra Rosas-Madrigal, Diana Ivette Aparicio-Bautista, Karina Reyes-Gordillo, M Raj Lakshman, Arturo Ortiz-Fernández, Héctor Quezada, Óscar Medina-Contreras, Saúl Villa-Treviño, Julio Isael Pérez-Carreón, and Jaime Arellanes-Robledo
Regulation of histone deacetylase activities and functions by phosphorylation and its physiological relevance., Sonali Bahl and Edward Seto
HDAC6 plays a noncanonical role in the regulation of antitumor immune responses, dissemination, and invasiveness of breast cancer, Debarati Banik, Satish Noonepalle, Melissa Hadley, Erica Palmer, Maria Gracia-Hernandez, Christian Zevallos-Delgado, Namratta Manhas, Hayk Simonyan, Colin N. Young, Anastas Popratiloff, Katherine B. Chiappinelli, Rohan Fernandes, Eduardo M. Sotomayor, and Alejandro Villagra
CpG-coated Prussian blue nanoparticles-based photothermal therapy combined with anti-CTLA-4 immune checkpoint blockade triggers a robust abscopal effect against neuroblastoma., Juliana Cano-Mejia, Anshi Shukla, Debbie K. Ledezma, Erica Palmer, Alejandro Villagra, and Rohan Fernandes
Targeting the E3 ubiquitin ligase PJA1 enhances tumor-suppressing TGFβ signaling, Jian Chen, Abhisek Mitra, Shulin Li, Shumei Song, Bao Ngoc Nguyen, Jiun Sheng Chen, Ji Hyun Shin, Nancy R. Gough, Paul Lin, Vincent Obias, Aiwu Ruth He, Zhixing Yao, Tathiane M. Malta, Houtan Noushmehr, Patricia S. Latham, Xiaoping Su, Asif Rashid, Bibhuti Mishra, Ray Chang Wu, and Lopa Mishra
Development of an Integrated Platform Using Multidisciplinary Real-World Data to Facilitate Biomarker Discovery for Medical Products, Stefan Dabic, Yasameen Azarbaijani, Tigran Karapetyan, Nilsa Loyo-Berrios, Vahan Simonyan, Terrie Kitchner, Murray Brilliant, and Yelizaveta Torosyan
Regulation of poly(a)-specific ribonuclease activity by reversible lysine acetylation., Eden A. Dejene, Yixuan Li, Zahra Showkatian, Hongbo Ling, and Edward Seto
Deregulation of Polycomb Repressive Complex-2 in Mantle Cell Lymphoma Confers Growth Advantage by Epigenetic Suppression of, Christos Demosthenous, Shiv K Gupta, Jing Sun, Yongsen Wang, Tammy P Troska, and Mamta Gupta
OncoMX: A Knowledgebase for Exploring Cancer Biomarkers in the Context of Related Cancer and Healthy Data., Hayley M. Dingerdissen, Frederic Bastian, K Vijay-Shanker, Marc Robinson-Rechavi, Amanda Bell, Nikhita Gogate, Samir Gupta, Evan Holmes, Robel Kahsay, Jonathon Keeney, Heather Kincaid, Charles Hadley King, David Liu, Daniel J. Crichton, and Raja Mazumder
Targeting Macrophages as a Therapeutic Option in Coronavirus Disease 2019, Maria Gracia-Hernandez, Eduardo M. Sotomayor, and Alejandro Villagra
Mutated CEACAMs Disrupt Transforming Growth Factor Beta Signaling and Alter the Intestinal Microbiome to Promote Colorectal Carcinogenesis, Shoujun Gu, Sobia Zaidi, Md Imtaiyaz Hassan, Taj Mohammad, Tathiane M. Malta, Houtan Noushmehr, Bryan Nguyen, Keith A. Crandall, Jigisha Srivastav, Vincent Obias, Paul Lin, Bao Ngoc Nguyen, Michael Yao, Ren Yao, Charles Hadley King, Raja Mazumder, Bibhuti Mishra, Shuyun Rao, and Lopa Mishra
Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection., Cortney E Heim, Megan E Bosch, Kelsey J Yamada, Amy L Aldrich, Sujata S Chaudhari, David Klinkebiel, Casey M Gries, Abdulelah A Alqarzaee, Yixuan Li, Vinai C Thomas, Edward Seto, Adam R Karpf, and Tammy Kielian
Bioinformatics and machine learning in gastrointestinal microbiome research and clinical application, Lindsay M. Hopson, Stephanie S. Singleton, John A. David, Atin Basuchoudhary, Stefanie Prast-Nielsen, Pavel Klein, Sabyasachi Sen, and Raja Mazumder
Streamlined Subpopulation, Subtype, and Recombination Analysis of HIV-1 Half-Genome Sequences Generated by High-Throughput Sequencing, Bhavna Hora, Naila Gulzar, Yue Chen, Konstantinos Karagiannis, Fangping Cai, Chang Su, Krista Smith, Vahan Simonyan, Sharaf Ali Shah, Manzoor Ahmed, Ana M. Sanchez, Mars Stone, Myron S. Cohen, Thomas N. Denny, Raja Mazumder, and Feng Gao
Ubiquitin-Conjugating Enzyme 2S Enhances Viral Replication by Inhibiting Type I IFN Production through Recruiting USP15 to Deubiquitinate TBK1., Li Huang, Hongyang Liu, Kunli Zhang, Qingwen Meng, Liang Hu, Yuanfeng Zhang, Zhida Xiang, Jiangnan Li, Yuying Yang, Yali Chen, Shangjin Cui, Hong Tang, Huadong Pei, Zhigao Bu, and Changjiang Weng
Phenotypic Subtyping and Re-analyses of Existing Transcriptomic Data from Autistic Probands in Simplex Families Reveal Differentially Expressed and ASD Trait-Associated Genes, Valerie W. Hu and Chongfeng Bi
Altered DNA methylation in a severe subtype of idiopathic autism: Evidence for sex differences in affected metabolic pathways., Valerie W. Hu, Yi Hong, Minyi Xu, and Henry T. Shu
BGL3 lncRNA mediates retention of the BRCA1/BARD1 complex at DNA damage sites., Zhaohua Hu, Shaojie Mi, Ting Zhao, Changmin Peng, Yihan Peng, Lulu Chen, Wenge Zhu, Yi Yao, Qibin Song, Xiangpan Li, Xinzhi Li, Chenxi Jia, and Huadong Pei
GlyGen data model and processing workflow., Robel Kahsay, Jeet Vora, Rahi Navelkar, Reza Mousavi, Brian C. Fochtman, Xavier Holmes, Nagarajan Pattabiraman, Rene Ranzinger, Rupali Mahadik, Tatiana Williamson, Sujeet Kulkarni, Gaurav Agarwal, Maria Martin, Preethi Vasudev, Leyla Garcia, Nathan Edwards, Wenjin Zhang, Darren A Natale, Karen Ross, Kiyoko F Aoki-Kinoshita, Matthew P Campbell, William S York, and Raja Mazumder
Recent Advances in Systems and Network Medicine: Meeting Report from the First International Conference in Systems and Network Medicine., Emma Kurnat-Thoma, Ancha Baranova, Pat Baird, Elia Brodsky, Atul J. Butte, Amrita K. Cheema, Feixiong Cheng, Shuchismita Dutta, Christina Grant, James Giordano, Anke H. Maitland-van der Zee, Douglas B. Fridsma, Robert Jarrin, Maricel G. Kann, Jonathon Keeney, Joseph Loscalzo, Guru Madhavan, Bradley A. Maron, Dennis K. McBride, Maeve McKean, Seong K. Mun, James C. Palmer, Bakul Patel, Kapil Parakh, Anne R. Pariser, Christian Pristipino, Timothy R D J Radstake, Harsha K. Rajasimha, William B. Rouse, Damjana Rozman, Alif Saleh, Harald H H W Schmidt, Nikolaus Schultz, Tavpritesh Sethi, Edwin K. Silverman, Jessica Skopac, Igor Svab, Sylvia Trujillo, James E. Valentine, Dinesh Verma, Bruce J. West, and Sona Vasudevan
Indocyanine green-nexturastat A-PLGA nanoparticles combine photothermal and epigenetic therapy for melanoma, Debbie K. Ledezma, Preethi B. Balakrishnan, Juliana Cano-Mejia, Elizabeth E. Sweeney, Melissa Hadley, Catherine M. Bollard, Alejandro Villagra, and Rohan Fernandes