Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells.
Document Type
Journal Article
Publication Date
4-16-2019
Journal
Sci Rep
Volume
9
Issue
1
DOI
10.1038/s41598-019-42237-3
APA Citation
Knox, T., Sahakian, E., Banik, D., Hadley, M., Palmer, E., Noonepalle, S., Kim, J., Powers, J., Gracia-Hernandez, M., Oliveira, V., Cheng, F., Chen, J., Barinka, C., Pinilla-Ibarz, J., Lee, N., Kozikowski, A., & Villagra, A. (2019). Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells.. Sci Rep, 9 (1). http://dx.doi.org/10.1038/s41598-019-42237-3
Peer Reviewed
1
Open Access
1
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This is an open access PubMed Central article.