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Submissions from 2018

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Donor-SpecificAnti-HLA Antibody Production Following Pediatric ABO-Incompatible Heart Transplantation., Chiu-Yu Chen, Paul Warner, Erin L Albers, Mariska S Kemna, Meghan Delaney, Borah J Hong, and Yuk M Law

A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples, Han Chen, Chunyan Li, Xinxin Peng, Zhicheng Zhou, John N. Weinstein, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, Timothy DeFreitas, Scott Frazer, Nils Gehlenborg, Gad Getz, David I. Heiman, Jaegil Kim, and Michael S. Lawrence

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context, Hua Sheng Chiu, Sonal Somvanshi, Ektaben Patel, Ting Wen Chen, Vivek P. Singh, Barry Zorman, Sagar L. Patil, Yinghong Pan, Sujash S. Chatterjee, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, Timothy DeFreitas, Scott Frazer, and Nils Gehlenborg

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Choosing Wisely for apheresis., Laura Connelly-Smith, Yvette C Tanhehco, Vishesh Chhibber, Meghan Delaney, Quentin Eichbaum, Christine Fernandez, Sarita Joshi, Joseph Schwartz, and Michael Linenberger

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How I reduce the risk of missed irradiation transfusion events in children., Meghan Delaney

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Bleeding emergencies in neonatal and paediatric patients: improving the quality of care using simulation., M Delaney, J Roberts, R Mazor, D Townsend-McCall, N H Saifee, M B Pagano, D C Matthews, and K Stone

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics, Li Ding, Matthew H. Bailey, Eduard Porta-Pardo, Vesteinn Thorsson, Antonio Colaprico, Denis Bertrand, David L. Gibbs, Amila Weerasinghe, Kuan lin Huang, Collin Tokheim, Isidro Cortés-Ciriano, Reyka Jayasinghe, Feng Chen, Lihua Yu, Sam Sun, Catharina Olsen, Jaegil Kim, Alison M. Taylor, Andrew D. Cherniack, Rehan Akbani, Chayaporn Suphavilai, Niranjan Nagarajan, Joshua M. Stuart, Gordon B. Mills, Matthew A. Wyczalkowski, Benjamin G. Vincent, Carolyn M. Hutter, Jean Claude Zenklusen, Katherine A. Hoadley, Michael C. Wendl, llya Shmulevich, Alexander J. Lazar, and David A. Wheeler

Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines, Kyle Ellrott, Matthew H. Bailey, Gordon Saksena, Kyle R. Covington, Cyriac Kandoth, Chip Stewart, Julian Hess, Singer Ma, Kami E. Chiotti, Michael McLellan, Heidi J. Sofia, Carolyn Hutter, Gad Getz, David Wheeler, Li Ding, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, and Carolyn M. Hutter

Cxcr4 is a potential target for diagnostic pet/ct imaging in barrett's dysplasia and esophageal adenocarcinoma, Hsin Yu Fang, Natasha Stephens Munch, Margret Schottelius, Jonas Ingermann, Haibo Liu, Michael Schauer, Stefan Stangl, Gabriele Multhoff, Katja Steiger, Carlos Gerngrob, Moritz Jesinghaus, Wilko Weichert, Anja A. Kuhl, Antonia R. Sepulveda, Hans Jurgen Wester, Timothy C. Wang, and Michael Quante

HER2 Heterogeneity in Gastroesophageal Cancer Detected by Testing Biopsy and Resection Specimens, Ladan Fazlollahi, Helen E. Remotti, Alina Iuga, Hui Min Yang, Stephen M. Lagana, and Antonia R. Sepulveda

Elevated resting blood pressure augments autonomic imbalance in posttraumatic stress disorder, Ida T. Fonkoue, Seth D. Norrholm, Paul J. Marvar, Yunxiao Li, Melanie L. Kankam, Barbara O. Rothbaum, and Jeanie Park

Single-nucleotide polymorphisms of stemness genes predicted to regulate RNA splicing, microRNA and oncogenic signaling are associated with prostate cancer survival, Jennifer A. Freedman, Yanru Wang, Xuechan Li, Hongliang Liu, Patricia G. Moorman, Daniel J. George, Norman H. Lee, Terry Hyslop, Qingyi Wei, and Steven R. Patierno

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers, Qingsong Gao, Wen Wei Liang, Steven M. Foltz, Gnanavel Mutharasu, Reyka G. Jayasinghe, Song Cao, Wen Wei Liao, Sheila M. Reynolds, Matthew A. Wyczalkowski, Lijun Yao, Lihua Yu, Sam Q. Sun, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, and Juok Cho

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types, Zhongqi Ge, Jake S. Leighton, Yumeng Wang, Xinxin Peng, Zhongyuan Chen, Hu Chen, Yutong Sun, Fan Yao, Jun Li, Huiwen Zhang, Jianfang Liu, Craig D. Shriver, Hai Hu, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, and Ye Wu

Application of unsupervised learning to hyperspectral imaging of cardiac ablation lesions, Shuyue Guan, Huda Asfour, Narine Sarvazyan, and Murray Loew

Lesion detection for cardiac ablation from auto-fluorescence hyperspectral images, Shuyue Guan, Murray Loew, Huda Asfour, Narine Sarvazyan, and Narine Muselimyan

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer, Katherine A. Hoadley, Christina Yau, Toshinori Hinoue, Denise M. Wolf, Alexander J. Lazar, Esther Drill, Ronglai Shen, Alison M. Taylor, Andrew D. Cherniack, Vésteinn Thorsson, Rehan Akbani, Reanne Bowlby, Christopher K. Wong, Maciej Wiznerowicz, Francisco Sanchez-Vega, A. Gordon Robertson, Barbara G. Schneider, Michael S. Lawrence, Houtan Noushmehr, Tathiane M. Malta, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, and Sudha Chudamani

3D printed venous valves, biocompatibility and functionality, Benjamin Holmes, Huda Asfour, Priyanka Koti, Nara Muselimyan, and Narine Sarvazyan

Pathogenic Germline Variants in 10,389 Adult Cancers, Kuan lin Huang, R. Jay Mashl, Yige Wu, Deborah I. Ritter, Jiayin Wang, Clara Oh, Marta Paczkowska, Sheila Reynolds, Matthew A. Wyczalkowski, Ninad Oak, Adam D. Scott, Michal Krassowski, Andrew D. Cherniack, Kathleen E. Houlahan, Reyka Jayasinghe, Liang Bo Wang, Daniel Cui Zhou, Di Liu, Song Cao, Young Won Kim, Amanda Koire, Joshua F. McMichael, Vishwanathan Hucthagowder, Tae Beom Kim, Abigail Hahn, Chen Wang, Michael D. McLellan, Fahd Al-Mulla, Kimberly J. Johnson, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, and Melpomeni Kasapi

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Non-meningothelial meningeal tumours with meningioangiomatosis-like pattern of spread., J B Iorgulescu, S Ferris, A Agarwal, S Casavilca Zambrano, D A Hill, R Schmidt, and A Perry

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Pathogen-inactivated blood products for pediatric patients: blood safety, patient safety, or both?, Cyril Jacquot and Meghan Delaney

The role of apoptosis in acetaminophen hepatotoxicity, Hartmut Jaeschke, Luqi Duan, Jephte Y. Akakpo, Anwar Farhood, and Anup Ramachandran

Systematic Analysis of Splice-Site-Creating Mutations in Cancer, Reyka G. Jayasinghe, Song Cao, Qingsong Gao, Michael C. Wendl, Nam Sy Vo, Sheila M. Reynolds, Yanyan Zhao, Héctor Climente-González, Shengjie Chai, Fang Wang, Rajees Varghese, Mo Huang, Wen Wei Liang, Matthew A. Wyczalkowski, Sohini Sengupta, Zhi Li, Samuel H. Payne, David Fenyö, Jeffrey H. Miner, Matthew J. Walter, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, and Sudha Chudamani

Design of an Online Histology and Pathology Atlas for Medical Students: an Instructional Aid to Self-Directed Learning, Rosalyn A. Jurjus, Gisela Butera, Janette M. Krum, Michelle Davis, Alexandra Mills, and Patricia S. Latham

Automated 3D-Printed Microfluidic Array for Rapid Nanomaterial-Enhanced Detection of Multiple Proteins, Karteek Kadimisetty, Spundana Malla, Ketki S. Bhalerao, Islam M. Mosa, Snehasis Bhakta, Norman H. Lee, and James F. Rusling

Automated 4-sample protein immunoassays using 3D-printed microfluidics, Karteek Kadimisetty, Andrew P. Spak, Ketki S. Bhalerao, Mohamed Sharafeldin, Islam M. Mosa, Norman H. Lee, and James F. Rusling

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients, André Kahles, Kjong Van Lehmann, Nora C. Toussaint, Matthias Hüser, Stefan G. Stark, Timo Sachsenberg, Oliver Stegle, Oliver Kohlbacher, Chris Sander, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, Timothy DeFreitas, Scott Frazer, and Nils Gehlenborg

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Transfusion Support of Minority Patients: Extended Antigen Donor Typing and Recruitment of Minority Blood Donors., Jenna Khan and Meghan Delaney

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas, Theo A. Knijnenburg, Linghua Wang, Michael T. Zimmermann, Nyasha Chambwe, Galen F. Gao, Andrew D. Cherniack, Huihui Fan, Hui Shen, Gregory P. Way, Casey S. Greene, Yuexin Liu, Rehan Akbani, Bin Feng, Lawrence A. Donehower, Chase Miller, Yang Shen, Mostafa Karimi, Haoran Chen, Pora Kim, Peilin Jia, Eve Shinbrot, Shaojun Zhang, Jianfang Liu, Hai Hu, Matthew H. Bailey, Christina Yau, Denise Wolf, Zhongming Zhao, John N. Weinstein, Lei Li, Li Ding, Gordon B. Mills, and Peter W. Laird

A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily, Anil Korkut, Sobia Zaidi, Rupa S. Kanchi, Shuyun Rao, Nancy R. Gough, Andre Schultz, Xubin Li, Philip L. Lorenzi, Ashton C. Berger, Gordon Robertson, Lawrence N. Kwong, Mike Datto, Jason Roszik, Shiyun Ling, Visweswaran Ravikumar, Ganiraju Manyam, Arvind Rao, Simon Shelley, Yuexin Liu, Zhenlin Ju, Donna Hansel, Guillermo de Velasco, Arjun Pennathur, Jesper B. Andersen, Colm J. O'Rourke, Kazufumi Ohshiro, Wilma Jogunoori, Bao Ngoc Nguyen, Shulin Li, Hatice U. Osmanbeyoglu, Jaffer A. Ajani, Sendurai A. Mani, and Andres Houseman

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics, Jianfang Liu, Tara Lichtenberg, Katherine A. Hoadley, Laila M. Poisson, Alexander J. Lazar, Andrew D. Cherniack, Albert J. Kovatich, Christopher C. Benz, Douglas A. Levine, Adrian V. Lee, Larsson Omberg, Denise M. Wolf, Craig D. Shriver, Vesteinn Thorsson, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, and Yunhu Wan

Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas, Yang Liu, Nilay S. Sethi, Toshinori Hinoue, Barbara G. Schneider, Andrew D. Cherniack, Francisco Sanchez-Vega, Jose A. Seoane, Farshad Farshidfar, Reanne Bowlby, Mirazul Islam, Jaegil Kim, Walid Chatila, Rehan Akbani, Rupa S. Kanchi, Charles S. Rabkin, Joseph E. Willis, Kenneth K. Wang, Shannon J. McCall, Lopa Mishra, Akinyemi I. Ojesina, Susan Bullman, Chandra Sekhar Pedamallu, Alexander J. Lazar, Ryo Sakai, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, and Zhining Wang

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The Pathology Workforce and Clinical Licensure, Robin Lorenz, Donald S. Karcher, Michael Gautreaux, Melvin Limson, and Dani Zander

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation, Tathiane M. Malta, Artem Sokolov, Andrew J. Gentles, Tomasz Burzykowski, Laila Poisson, John N. Weinstein, Bożena Kamińska, Joerg Huelsken, Larsson Omberg, Olivier Gevaert, Antonio Colaprico, Patrycja Czerwińska, Sylwia Mazurek, Lopa Mishra, Holger Heyn, Alex Krasnitz, Andrew K. Godwin, Alexander J. Lazar, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, Jia Liu, and Laxmi Lolla

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Nonepithelial Neoplasms of the Pancreas, Part 2: Malignant Tumors and Tumors of Uncertain Malignant Potential From the Radiologic Pathology Archives., Maria A Manning, Edina E Paal, Amogh Srivastava, and Koenraad J Mortele

Nonepithelial neoplasms of the pancreas, part 2: Malignant tumors and tumors of uncertain malignant potential, Maria A. Manning, Edina E. Paal, Amogh Srivastava, and Koenraad J. Mortele

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers, Xinxin Peng, Zhongyuan Chen, Farshad Farshidfar, Xiaoyan Xu, Philip L. Lorenzi, Yumeng Wang, Feixiong Cheng, Lin Tan, Kamalika Mojumdar, Di Du, Zhongqi Ge, Jun Li, George V. Thomas, Kivanc Birsoy, Lingxiang Liu, Huiwen Zhang, Zhongming Zhao, Calena Marchand, John N. Weinstein, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, and Jia Liu

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IBD LIVE Case Series: Case 9: Do Race and Extraintestinal Manifestations Affect Treatment of Severe Crohn's Colitis?, Siobhan S Proksell, Julia B Greer, Brian K Theisen, Peter L Davis, Joel R Rosh, David J Keljo, Alka Goyal, Samir A Shah, Myron H Brand, Hans H Herfarth, Raymond K Cross, Corey A Siegel, Walter A Koltun, Kim L Isaacs, and Miguel D Regueiro

Gut Colonization with Methanogenic Archaea Lowers Plasma Trimethylamine N-oxide Concentrations in Apolipoprotein e−/− Mice, Ali Ramezani, Thomas D. Nolin, Ian R. Barrows, Myrna G. Serrano, Gregory A. Buck, Renu Regunathan-Shenk, Raymond E. West, Patricia S. Latham, Richard Amdur, and Dominic S. Raj

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma, Christopher J. Ricketts, Aguirre A. De Cubas, Huihui Fan, Christof C. Smith, Martin Lang, Ed Reznik, Reanne Bowlby, Ewan A. Gibb, Rehan Akbani, Rameen Beroukhim, Donald P. Bottaro, Toni K. Choueiri, Richard A. Gibbs, Andrew K. Godwin, Scott Haake, A. Ari Hakimi, Elizabeth P. Henske, James J. Hsieh, Thai H. Ho, Rupa S. Kanchi, Bhavani Krishnan, David J. Kwaitkowski, Wembin Lui, Maria J. Merino, Gordon B. Mills, Jerome Myers, Michael L. Nickerson, Victor E. Reuter, Laura S. Schmidt, C. Simon Shelley, Hui Shen, Brian Shuch, and Sabina Signoretti

Erratum: The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma (Cell Reports (2018) 23(1) (313–326.e5) (S2211124718304364) (10.1016/j.celrep.2018.03.075)), Christopher J. Ricketts, Aguirre A. De Cubas, Huihui Fan, Christof C. Smith, Martin Lang, Ed Reznik, Reanne Bowlby, Ewan A. Gibb, Rehan Akbani, Rameen Beroukhim, Donald P. Bottaro, Toni K. Choueiri, Richard A. Gibbs, Andrew K. Godwin, Scott Haake, A. Ari Hakimi, Elizabeth P. Henske, James J. Hsieh, Thai H. Ho, Rupa S. Kanchi, Bhavani Krishnan, David J. Kwiatkowski, Wembin Lui, Maria J. Merino, Gordon B. Mills, Jerome Myers, Michael L. Nickerson, Victor E. Reuter, Laura S. Schmidt, C. Simon Shelley, Hui Shen, Brian Shuch, and Sabina Signoretti

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images, Joel Saltz, Rajarsi Gupta, Le Hou, Tahsin Kurc, Pankaj Singh, Vu Nguyen, Dimitris Samaras, Kenneth R. Shroyer, Tianhao Zhao, Rebecca Batiste, John Van Arnam, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, and Timothy DeFreitas

Oncogenic Signaling Pathways in The Cancer Genome Atlas, Francisco Sanchez-Vega, Marco Mina, Joshua Armenia, Walid K. Chatila, Augustin Luna, Konnor C. La, Sofia Dimitriadoy, David L. Liu, Havish S. Kantheti, Sadegh Saghafinia, Debyani Chakravarty, Foysal Daian, Qingsong Gao, Matthew H. Bailey, Wen Wei Liang, Steven M. Foltz, Ilya Shmulevich, Li Ding, Zachary Heins, Angelica Ochoa, Benjamin Gross, Jianjiong Gao, Hongxin Zhang, Ritika Kundra, Cyriac Kandoth, Istemi Bahceci, Leonard Dervishi, Ugur Dogrusoz, Wanding Zhou, Hui Shen, Peter W. Laird, Gregory P. Way, and Casey S. Greene

CRM1/XPO1 expression in pancreatic adenocarcinoma correlates with survivin expression and the proliferative activity, David M. Saulino, Pamela S. Younes, Jennifer M. Bailey, and Mamoun Younes

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas, Franz X. Schaub, Varsha Dhankani, Ashton C. Berger, Mihir Trivedi, Anne B. Richardson, Reid Shaw, Wei Zhao, Xiaoyang Zhang, Andrea Ventura, Yuexin Liu, Donald E. Ayer, Peter J. Hurlin, Andrew D. Cherniack, Robert N. Eisenman, Brady Bernard, Carla Grandori, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, and Todd Pihl

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DICER1 and associated conditions: Identification of at-risk individuals and recommended surveillance strategies., Kris Ann P Schultz, Gretchen M Williams, Junne Kamihara, Douglas R Stewart, Anne K Harris, Ashley Hill, and +several additional authors

Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types, Michael Seiler, Shouyong Peng, Anant A. Agrawal, James Palacino, Teng Teng, Ping Zhu, Peter G. Smith, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, Timothy DeFreitas, Scott Frazer, Nils Gehlenborg, Gad Getz, and David I. Heiman

MicroRNA and mRNA expression associated with ectopic germinal centers in thymus of myasthenia gravis, Manjistha Sengupta, Bi Dar Wang, Norman H. Lee, Alexander Marx, Linda L. Kusner, and Henry J. Kaminski

Molecular basis of diseases of the gastrointestinal tract, Antonia R. Sepulveda and Armando J. Del Portillo

Management of pregnancy sensitized with anti-Inb with monocyte monolayer assay and maternal blood donation., Raj Shree, Kimberly K Ma, Lay S Er, and Meghan Delaney

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PD-L1 checkpoint inhibition and anti-CTLA-4 whole tumor cell vaccination counter adaptive immune resistance: A mouse neuroblastoma model that mimics human disease., Priya Srinivasan, Xiaofang Wu, Mousumi Basu, Christopher Rossi, and Anthony D Sandler

Hyperspectral imaging for label-free in vivo identification of myocardial scars and sites of radiofrequency ablation lesions, Luther M. Swift, Huda Asfour, Narine Muselimyan, Cinnamon Larson, Kenneth Armstrong, and Narine A. Sarvazyan

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Tissue Acylcarnitine Status in a Mouse Model of Mitochondrial β-oxidation Deficiency during Metabolic Decompensation due to Influenza Virus Infection., Tatiana N Tarasenko, Kristina Cusmano-Ozog, and Peter J McGuire

Genomic and Functional Approaches to Understanding Cancer Aneuploidy, Alison M. Taylor, Juliann Shih, Gavin Ha, Galen F. Gao, Xiaoyang Zhang, Ashton C. Berger, Steven E. Schumacher, Chen Wang, Hai Hu, Jianfang Liu, Alexander J. Lazar, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, and Timothy DeFreitas

The Immune Landscape of Cancer, Vésteinn Thorsson, David L. Gibbs, Scott D. Brown, Denise Wolf, Dante S. Bortone, Tai Hsien Ou Yang, Eduard Porta-Pardo, Galen F. Gao, Christopher L. Plaisier, James A. Eddy, Elad Ziv, Aedin C. Culhane, Evan O. Paull, I. K.Ashok Sivakumar, Andrew J. Gentles, Raunaq Malhotra, Farshad Farshidfar, Antonio Colaprico, Joel S. Parker, Lisle E. Mose, Nam Sy Vo, Jianfang Liu, Yuexin Liu, Janet Rader, Varsha Dhankani, Sheila M. Reynolds, Reanne Bowlby, Andrea Califano, Andrew D. Cherniack, Dimitris Anastassiou, Davide Bedognetti, Arvind Rao, and Ken Chen

Aberrant RNA splicing in cancer and drug resistance, Bi Dar Wang and Norman H. Lee

Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer, Yumeng Wang, Xiaoyan Xu, Dejan Maglic, Michael T. Dill, Kamalika Mojumdar, Patrick Kwok Shing Ng, Kang Jin Jeong, Yiu Huen Tsang, Daniela Moreno, Venkata Hemanjani Bhavana, Xinxin Peng, Zhongqi Ge, Hu Chen, Jun Li, Zhongyuan Chen, Huiwen Zhang, Leng Han, Di Du, Chad J. Creighton, Gordon B. Mills, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, and Sudha Chudamani

lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer, Zehua Wang, Bo Yang, Min Zhang, Weiwei Guo, Zhiyuan Wu, Yue Wang, Lin Jia, Song Li, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, Timothy DeFreitas, Scott Frazer, Nils Gehlenborg, and Gad Getz

AGA White Paper: Optimizing Endoscopic Ultrasound–Guided Tissue Acquisition and Future Directions, Sachin Wani, V. Raman Muthusamy, Cindy M. McGrath, Antonia R. Sepulveda, Ananya Das, Wells Messersmith, Michael L. Kochman, and Janak Shah

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas, Gregory P. Way, Francisco Sanchez-Vega, Konnor La, Joshua Armenia, Walid K. Chatila, Augustin Luna, Chris Sander, Andrew D. Cherniack, Marco Mina, Giovanni Ciriello, Nikolaus Schultz, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, and Timothy DeFreitas

Protective effect of genetic deletion of pannexin1 in experimental mouse models of acute and chronic liver disease, Joost Willebrords, Michaël Maes, Isabel Veloso Alves Pereira, Tereza Cristina da Silva, Veronica Mollica Govoni, Valéria Veras Lopes, Sara Crespo Yanguas, Valery I. Shestopalov, Marina Sayuri Nogueira, Inar Alves de Castro, Anwar Farhood, Inge Mannaerts, Leo van Grunsven, Jephte Akakpo, Margitta Lebofsky, Hartmut Jaeschke, Bruno Cogliati, and Mathieu Vinken

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Prenatal treatment of ornithine transcarbamylase deficiency., Yael Wilnai, Yair J Blumenfeld, Kristina Cusmano, Susan R Hintz, Deborah Alcorn, William E Benitz, William E Berquist, Jonathan A Bernstein, Ricardo O Castillo, Waldo Concepcion, Tina M Cowan, Kenneth L Cox, Deirdre J Lyell, Carlos O Esquivel, Margaret Homeyer, Louanne Hudgins, Melissa Hurwitz, Jonathan P Palma, Susan Schelley, Vishnu Priya Akula, Marshall L Summar, and Gregory M Enns

Expression of estrogen receptor beta isoforms in pancreatic adenocarcinoma, Mamoun Younes, Charles J. Ly, Kanchan Singh, Atilla Ertan, Pamela S. Younes, and Jennifer M. Bailey

Submissions from 2017

The Impact of Infectious Diseases Consultation on the Choice of Antifungal Therapy in Patients with Candidemia, Cristina Amado, Paul Blair, John Keiser, and Marc Oliver Siegel

KSHV-associated and EBV-associated germinotropic lymphoproliferative disorder: New findings and review of the literature, Tapan Bhavsar, John C. Lee, Yvonne Perner, Mark Raffeld, Liqiang Xi, Stefania Pittaluga, and Elaine S. Jaffe

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Mycobacterium fortuitum empyema associated with an indwelling pleural catheter: Case report and review of the literature., Paul Blair, Mahdi Moshgriz, Marc Siegel, and John Keiser

In vivo analysis of mucosal lipids reveals histological disease activity in ulcerative colitis using endoscope-coupled raman spectroscopy, Hao Ding, Andrew W. Dupont, Shashideep Singhal, Larry D. Scott, Sushovan Guha, Mamoun Younes, and Xiaohong Bi

Effect of physiological factors on the biochemical properties of colon tissue – an in vivo Raman spectroscopy study, Hao Ding, Andrew W. Dupont, Shashideep Singhal, Larry D. Scott, Sushovan Guha, Mamoun Younes, Yuanqing Ye, and Xiaohong Bi

Pediatric unilateral facial swelling, Awatef Draz, Wael Elias, Azza El-Sissi, and Min Ling Liu

Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity, Kuo Du, Anwar Farhood, and Hartmut Jaeschke

Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity, Kuo Du, Anup Ramachandran, Mitchell R. McGill, Abdellah Mansouri, Tarik Asselah, Anwar Farhood, Benjamin L. Woolbright, Wen Xing Ding, and Hartmut Jaeschke

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Reward magnitude tracking by neural populations in ventral striatum., Ana M Fiallos, Sarah J Bricault, Lili X Cai, Hermoon A Worku, Matthew T Colonnese, Gil G Westmeyer, and Alan Jasanoff

Molecular characterization of autonomic and neuropeptide receptors, Claire M. Fraser and Norman H. Lee

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The anatomy of the TNM for colon cancer., Donald E Henson, Matthew T Hueman, Dechang Chen, Jigar A Patel, Huan Wang, and Arnold M Schwartz

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Parental Versus Non-Parental-Directed Donation: An 11-year Experience of Infectious Disease Testing at a Pediatric Tertiary Care Blood Donor Center., Cyril Jacquot, Andrew Seo, Peter M Miller, Niara Lezama, Valli R Criss, Camilla Colvin, Naomi L C Luban, and Edward C C Wong

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ALK-Positive Primary Central Nervous System Anaplastic Large T-Cell Lymphoma: A Unique Case Presentation, Amar Jariwala, M Isabel Almira-Suarez, and Elsie Lee

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Acute Myelomonocytic Leukemia With Tetrasomy 8: Histologic and Immunophenotypic Features Mimicking Acute Promyelocytic Leukemia, Amar Jariwala and Donald S. Karcher

A role of central NELL2 in the regulation of feeding behavior in rats, Jin Kwon Jeong, Jae Geun Kim, Han Rae Kim, Tae Hwan Lee, Jeong Woo Park, and Byung Ju Lee

Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus, Ming Jiang, Haiyan Li, Yongchun Zhang, Ying Yang, Rong Lu, Kuancan Liu, Sijie Lin, Xiaopeng Lan, Haikun Wang, Han Wu, Jian Zhu, Zhongren Zhou, Jianming Xu, Dong Kee Lee, Lanjing Zhang, Yuan Cho Lee, Jingsong Yuan, Julian A. Abrams, Timothy C. Wang, Antonia R. Sepulveda, Qi Wu, Huaiyong Chen, Xin Sun, Junjun She, Xiaoxin Chen, and Jianwen Que

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Impact of automatic infectious diseases consultation on the management of fungemia at a large academic medical center., Travis M Jones, Richard H Drew, Dustin T Wilson, Christina Sarubbi, Deverick J Anderson, and John Keiser

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The effect of HIV infection and HCV viremia on Inflammatory Mediators and Hepatic Injury-The Women's Interagency HIV Study., Sheila M Keating, Jennifer L Dodge, Philip J Norris, John Heitman, Stephen J Gange, Audrey L French, Marshall J Glesby, Brian R Edlin, Patricia S Latham, Maria C Villacres, Ruth M Greenblatt, and Marion G Peters

The effect of HIV infection and HCV viremia on inflammatory mediators and hepatic injury—The Women’s Interagency HIV Study, Sheila M. Keating, Jennifer L. Dodge, Philip J. Norris, John Heitman, Stephen J. Gange, Audrey L. French, Marshall J. Glesby, Brian R. Edlin, Patricia S. Latham, Maria C. Villacres, Ruth M. Greenblatt, and Marion G. Peters

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Quantification of thyroid cancer and multinodular goiter risk in the DICER1 syndrome: a family-based cohort study., Nicholas E Khan, Andrew J Bauer, Kris Ann P Schultz, Leslie Doros, Rosamma M Decastro, Alexander Ling, Maya B Lodish, Laura A Harney, Ron G Kase, Ann G Carr, Christopher T Rossi, Amanda Field, Anne K Harris, Gretchen M Williams, Louis P Dehner, Yoav H Messinger, D Ashley Hill, and Douglas R Stewart

Tumor SQSTM1 (p62) expression and T cells in colorectal cancer, Keisuke Kosumi, Yohei Masugi, Juhong Yang, Zhi Rong Qian, Sun A. Kim, Wanwan Li, Yan Shi, Annacarolina da Silva, Tsuyoshi Hamada, Li Liu, Mancang Gu, Tyler S. Twombly, Yin Cao, David A. Barbie, Katsuhiko Nosho, Hideo Baba, Wendy S. Garrett, Jeffery A. Meyerhardt, Edward L. Giovannucci, Andrew T. Chan, Charles S. Fuchs, Shuji Ogino, and Reiko Nishihara

An efficient concordant integrative analysis of multiple large-scale two-sample expression data sets, Yinglei Lai, Fanni Zhang, Tapan K. Nayak, Reza Modarres, Norman H. Lee, and Timothy A. McCaffrey

Detecting discordance enrichment among a series of two-sample genome-wide expression data sets, Yinglei Lai, Fanni Zhang, Tapan K. Nayak, Reza Modarres, Norman H. Lee, and Timothy A. McCaffrey

Microcalcifications in stone-obstructed human submandibular gland are associated with apoptosis and cell proliferation, Ivan Lau, Ajay Potluri, Cliff Lawrence Ibeh, Robert S. Redman, Edina Paal, and Bidhan C. Bandyopadhyay

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Microcalcifications in stone-obstructed human submandibular gland are associated with apoptosis and cell proliferation., Ivan Lau, Ajay Potluri, Cliff-Lawrence Ibeh, Robert S Redman, Edina Paal, and Bidhan C Bandyopadhyay

Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett'slike esophagus, Yoomi Lee, Aleksandra M. Urbanska, Yoku Hayakawa, Hongshan Wang, Andrew S. Au, Aesis M. Luna, Wenju Chang, Guangchun Jin, Govind Bhagat, Julian A. Abrams, Richard A. Friedman, Andrea Varro, Kenneth K. Wang, Malcolm Boyce, Anil K. Rustgi, Antonia R. Sepulveda, Michael Quante, and Timothy C. Wang

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Pediatric Cystic Nephroma Is Morphologically, Immunohistochemically, and Genetically Distinct From Adult Cystic Nephroma., Yunjie Li, Bruce R Pawel, Dana A Hill, Jonathan I Epstein, and Pedram Argani

Connexin hemichannel inhibition reduces acetaminophen-induced liver injury in mice, Michaël Maes, Sara Crespo Yanguas, Joost Willebrords, James L. Weemhoff, Tereza Cristina da Silva, Elke Decrock, Margitta Lebofsky, Isabel Veloso Alves Pereira, Luc Leybaert, Anwar Farhood, Hartmut Jaeschke, Bruno Cogliati, and Mathieu Vinken

Erratum to: Inhibition of pannexin1 channels alleviates acetaminophen-induced hepatotoxicity (Archives of Toxicology, (2017), 91, 5, (2245-2261), 10.1007/s00204-016-1885-6), Michaël Maes, Mitchell R. McGill, Tereza Cristina da Silva, Chloé Abels, Margitta Lebofsky, James L. Weemhoff, Taynã Tiburcio, Isabel Veloso Alves Pereira, Joost Willebrords, Sara Crespo Yanguas, Anwar Farhood, Alain Beschin, Jo A. Van Ginderachter, Silvia Penuela, Hartmut Jaeschke, Bruno Cogliati, and Mathieu Vinken

Inhibition of pannexin1 channels alleviates acetaminophen-induced hepatotoxicity, Michaël Maes, Mitchell R. McGill, Tereza Cristina da Silva, Chloé Abels, Margitta Lebofsky, James L. Weemhoff, Taynã Tiburcio, Isabel Veloso Alves Pereira, Joost Willebrords, Sara Crespo Yanguas, Anwar Farhood, Alain Beschin, Jo A. Van Ginderachter, Silvia Penuela, Hartmut Jaeschke, Bruno Cogliati, and Mathieu Vinken

Genomes of Fasciola hepatica from the Americas Reveal Colonization with Neorickettsia Endobacteria Related to the Agents of Potomac Horse and Human Sennetsu Fevers, Samantha N. McNulty, Jose F. Tort, Gabriel Rinaldi, Kerstin Fischer, Bruce A. Rosa, Pablo Smircich, Santiago Fontenla, Young Jun Choi, Rahul Tyagi, Kymberlie Hallsworth-Pepin, Victoria H. Mann, Lakshmi Kammili, Patricia S. Latham, Nicolas Dell’Oca, Fernanda Dominguez, Carlos Carmona, Peter U. Fischer, Paul J. Brindley, and Makedonka Mitreva

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Medicolegal Death Investigation of Sudden Unexpected Infant Deaths., Roger A Mitchell, Constance DiAngelo, and Daniel Morgan

Osteopontin is linked with AKT, FoxO1, and myostatin in skeletal muscle cells, Peter P. Nghiem, Joe N. Kornegay, Kitipong Uaesoontrachoon, Luca Bello, Ying Yin, Akanchha Kesari, Priya Mittal, Scott J. Schatzberg, Gina M. Many, Norman H. Lee, and Eric P. Hoffman

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A 66 year-old woman with hemoptysis., Falin B. Patel, Kara S. Couch, Sean McNish, Jonathan D. Miller, Robert Siegel, Samantha Easley, and Victoria K. Shanmugam

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Clinicopathologic Study of Calcifying Fibrous Tumor of the Gastrointestinal Tract: A Case Series., Maryam Kherad Pezhouh, M Katayoon Rezaei, Maryam Shabihkhani, Arunima Ghosh, Deborah Belchis, Elizabeth A Montgomery, and Lysandra Voltaggio

Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma, Benjamin J. Raphael, Ralph H. Hruban, Andrew J. Aguirre, Richard A. Moffitt, Jen Jen Yeh, Chip Stewart, A. Gordon Robertson, Andrew D. Cherniack, Manaswi Gupta, Gad Getz, Stacey B. Gabriel, Matthew Meyerson, Carrie Cibulskis, Suzanne S. Fei, Toshinori Hinoue, Hui Shen, Peter W. Laird, Shiyun Ling, Yiling Lu, Gordon B. Mills, Rehan Akbani, Phillipe Loher, Eric R. Londin, Isidore Rigoutsos, Aristeidis G. Telonis, Ewan A. Gibb, Anna Goldenberg, Aziz M. Mezlini, Katherine A. Hoadley, Eric Collisson, Eric Lander, Bradley A. Murray, and Julian Hess

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Diagnosis of LCHAD/TFP deficiency in an at risk newborn using umbilical cord blood acylcarnitine analysis, Donna Raval, Kristina Cusmano-Ozog, Omar Ayyub, Callie Jenevein, Laura Kofman, Brendan Lanpher, Natalie Hauser, and Debra Regier