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Submissions from 2016

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Blimp-1–mediated CD4 T cell exhaustion causes CD8 T cell dysfunction during chronic toxoplasmosis, Sujin Hwang, Dustin A. Cobb, Rajarshi Bhadra, Ben Youngblood, and Imtiaz A. Khan

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A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes., R. Brad Jones, Stefanie Mueller, Rachel O'Connor, Katherine Rimpel, Derek D Sloan, Allison S. Thomas, Sara Karandish, Szu-Han Huang, and +13 more

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HIV-specific CD8+ T cells and HIV eradication, R. Brad Jones and Bruce Walker

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Epigenetic modulation, stress and plasticity in susceptibility of the snail host, Biomphalaria glabrata, to Schistosoma mansoni infection., Matty Knight, Wannaporn Ittiprasert, Halime D. Arican-Goktas, and Joanna M. Bridger

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Persistent HIV Type 1 Seronegative Status Is Associated With Lower CD8+ T-Cell Activation., Peter J. Kuebler, Megha L. Mehrotra, Brian I. Shaw, Kaitlyn S. Leadabrand, Jeffrey M. Milush, Vanessa A. York, Patricia Defechereux, Robert M. Grant, Esper G. Kallás, and Douglas F. Nixon

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Brief Report: HIV-1 gp120 T-Cell Responses Correspond to Infection Outcomes in the Global iPrEx Chemoprophylaxis Trial., Peter J Kuebler, Brian I Shaw, Kaitlyn S Leadabrand, Megha L Mehrotra, Robert M Grant, Esper G Kallás, and Douglas F Nixon

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Cytomegalovirus Restructures Lipid Rafts via a US28/CDC42-Mediated Pathway, Enhancing Cholesterol Efflux from Host Cells., Hann Low, Nigora Mukhamedova, Huanhuan L Cui, Brian P McSharry, Selmir Avdic, Michael Bukrinsky, and +12 additional authors

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Lipidomic dataset of plasma from patients infected with wild type and nef-deficient HIV-1 strain., Peter Meikle, Hann Low, Melissa J Churchill, Michael Bukrinsky, and Dmitri Sviridov

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IL-21 Is Important for Induction of KLRG1+ Effector CD8 T Cells during Acute Intracellular Infection., Magali M. Moretto and Imtiaz A. Khan

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IL-21 Is important for induction of KLRG1+ effector CD8 T cells during acute intracellular infection., Magali M. Moretto and Imtiaz A. Khan

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Analysis of ABCA1 and Cholesterol Efflux in HIV-Infected Cells., Nigora Mukhamedova, Beda Brichacek, Christina Darwish, Anastas Popratiloff, Dmitri Sviridov, and Michael Bukrinsky

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Small GTPase ARF6 Regulates Endocytic Pathway Leading to Degradation of ATP-Binding Cassette Transporter A1., Nigora Mukhamedova, Anh Hoang, Huanhuan L Cui, Irena Carmichael, Ying Fu, Michael Bukrinsky, and Dmitri Sviridov

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Immunization and challenge shown by hamsters infected with Opisthorchis viverrini following exposure to gamma-irradiated metacercariae of this carcinogenic liver fluke, A. Papatpremsiri, P. Junpue, A. Loukas, Paul J. Brindley, Jeffrey M. Bethony, B. Sripa, and T. Laha

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Inversion of the Vδ1 to Vδ2 γδ T cell ratio in CVID is not restored by IVIg and is associated with immune activation and exhaustion., Dominic Paquin-Proulx, Nathália Silveira Barsotti, Bianca A N Santos, Ana Karolina B B Marinho, Cristina M Kokron, Karina I Carvalho, Myrthes T Barros, Jorge Kalil, Douglas F. Nixon, and Esper G Kallas

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Innate Invariant NKT Cell Recognition of HIV-1-Infected Dendritic Cells Is an Early Detection Mechanism Targeted by Viral Immune Evasion, Dominic Paquin-Proulx, Anna Gibbs, Susanna M Bächle, Antonio Checa, Andrea Introini, Edwin Leeansyah, Craig E Wheelock, Douglas F. Nixon, and +4 others

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Innate Invariant NKT Cell Recognition of HIV-1-Infected Dendritic Cells Is an Early Detection Mechanism Targeted by Viral Immune Evasion., Dominic Paquin-Proulx, Anna Gibbs, Susanna M Bächle, Antonio Checa, Andrea Introini, Edwin Leeansyah, Craig E Wheelock, Douglas F. Nixon, Kristina Broliden, Annelie Tjernlund, Markus Moll, and Johan K Sandberg

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T-cell therapies for HIV: Preclinical successes and current clinical strategies., Shabnum Patel, R. Brad Jones, Douglas F. Nixon, and Catherine M. Bollard

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Functionally Active HIV-Specific T Cells that Target Gag and Nef Can Be Expanded from Virus-Naïve Donors and Target a Range of Viral Epitopes: Implications for a Cure Strategy after Allogeneic Hematopoietic Stem Cell Transplantation., Shabnum Patel, Sharon Lam, Conrad Russell Cruz, Kaylor Wright, Christina Cochran, Richard F. Ambinder, and Catherine M. Bollard

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Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction, Michelle Pleet, Allison Mathiesen, Catherine DeMarino, Yao Akpamagbo, Robert Barclay, Sergey N. Iordanskiy, and +6 additional authors

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Antiviral CD8(+) T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion., Srinika Ranasinghe, Pedro A Lamothe, Damien Z Soghoian, Samuel W Kazer, Michael B Cole, Alex K Shalek, Nir Yosef, R. Brad Jones, Faith Donaghey, Chioma Nwonu, Priya Jani, Gina M Clayton, Frances Crawford, Janice White, Alana Montoya, Karen Power, Todd M Allen, Hendrik Streeck, Daniel E Kaufmann, Louis J Picker, John W Kappler, and Bruce D Walker

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RNAi-mediated gene knockdown by microinjection in the model entomopathogenic nematode Heterorhabditis bacteriophora., Ramesh Ratnappan, Jonathan Vadnal, Melissa Keaney, Ioannis Eleftherianos, Damien O'Halloran, and John M. Hawdon

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p16INK4a Expression and Immunologic Aging in Chronic HIV Infection, Susan Ribeiro, Jeffrey Milush, Edecio Cunha-Neto, Esper Kallas, Jorge Kalil, Luiz Felipe D. Passero, Peter W. Hunt, Steven Deeks, Douglas F. Nixon, and Devi SenGupta

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Carbonyl stress phenomena during chronic infection with Opisthorchis felineus., Irina V Saltykova, Ludmilla M Ogorodova, Vladimir V Ivanov, Aleksandr O Bogdanov, Elena A Gereng, Ekaterina A Perina, Paul J. Brindley, and Alexsey E Sazonov

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Biliary Microbiota, Gallstone Disease and Infection with Opisthorchis felineus., Irina V. Saltykova, Vjacheslav A Petrov, Maria D Logacheva, Polina G Ivanova, Nikolay V Merzlikin, Alexey E Sazonov, Ludmila M Ogorodova, and Paul J. Brindley

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Cellular minichromosome maintenance complex component 5 (MCM5) is incorporated into HIV-1 virions and modulates viral replication in the newly infected cells., Steven Santos, Yuri Obukhov, Sergei Nekhai, Tatiana Pushkarsky, Beda Brichacek, Michael Bukrinsky, and Sergey Iordanskiy

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A biobank to support HIV malignancy research for sub-Saharan Africa., Johann Wilhelm Schneider, Micheline Sanderson, Dieter Geiger, Mostafa Nokta, and Sylvia Silver

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Live Cell Imaging of ABCA1 Downregulation by HIV-1 Nef in an Experimental Model of HeLa ABCA1-GFP., Johanna Siegel, Christina Darwish, Anastas Popratiloff, Michael Bukrinsky, and Beda Brichacek

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HIV-1 Integrates Widely throughout the Genome of the Human Blood Fluke Schistosoma mansoni., Sutas Suttiprapa, Gabriel Rinaldi, Isheng J Tsai, Victoria H. Mann, Larisa Dubrovsky, Hong-Bin Yan, Nancy Holroyd, Thomas Huckvale, Caroline Durrant, Anna V Protasio, Tatiana Pushkarsky, Sergey Iordanskiy, Matthew Berriman, Michael I. Bukrinsky, and Paul J. Brindley

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Chicken IgY-based coproantigen capture ELISA for diagnosis of human opisthorchiasis., Salma Teimoori, Yuji Arimatsu, Thewarach Laha, Sasithorn Kaewkes, Piya Sereerak, Manop Sripa, Sirikachorn Tangkawattana, Paul J. Brindley, and Banchob Sripa

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Cold Atmospheric Plasma Inhibits HIV-1 Replication in Macrophages by Targeting Both the Virus and the Cells., Olga Volotskova, Larisa Dubrovsky, Michael Keidar, and Michael Bukrinsky

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Microfluidic platform for electrophysiological recordings from host-stage hookworm and Ascaris suum larvae: A new tool for anthelmintic research, Janis Weeks, William Roberts, Kristin Robinson, Melissa Keaney, Jon Vermiere, Joseph Urban, Shawn Lockery, and John M. Hawdon

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Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model, Cory White, Bastiaan Moesker, Nadejda Beliakova-Bethell, Laura Martins, Celsa Spina, Alberto Bosque, and +4 additional authors

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Identification and spontaneous immune targeting of an endogenous retrovirus K envelope protein in the Indian rhesus macaque model of human disease., Helen L Wu, Enrique J Léon, Lyle T Wallace, Francesca A Nimiyongskul, Matthew B Buechler, Laura P Newman, Philip A Castrovinci, R Paul Johnson, Robert J Gifford, R. Brad Jones, and Jonah B Sacha

Submissions from 2015

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Modulating APOBEC expression enhances DNA vaccine immunogenicity., Rafael Ribeiro Almeida, Rui André Saraiva Raposo, Fernanda Caroline Coirada, Jamile Ramos da Silva, Luís Carlos de Souza Ferreira, Jorge Kalil, Douglas F. Nixon, and Edecio Cunha-Neto

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Jan van der Noordaa (1934-2015); A Virologist Pur Sang., Ben Berkhout and Michael Bukrinsky

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The role of estrogens and estrogen receptor signaling pathways in cancer and infertility: the case of schistosomes., Mónica C Botelho, Helena Alves, Alberto Barros, Gabriel Rinaldi, Paul J Brindley, and Mário Sousa

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Challenges and opportunities for T cell-mediated strategies to eliminate HIV reservoirs, Mark A. Brockman, R. Brad Jones, and Zabrina L. Brumme

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Extracellular cyclophilins in health and disease., Michael Bukrinsky

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Carcinogenic liver fluke secretes extracellular vesicles that promote cholangiocytes to adopt a tumorigenic phenotype, Sujittra Chaidayet, Javier Sotillo, Michael Smout, Cinzia Cantacessi, Malcolm Jones, Paul J. Brindley, Jeffrey M. Bethony, and +9 additional authors

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Major Histocompatibility Complex Class II Deficiency due to a Novel Mutation in RFXANK in a Child of Mexican Descent., Katherine Clarridge, David Leitenberg, Brett Loechelt, Capuchine Picard, and Michael Keller

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The carcinogenic liver fluke Opisthorchis viverrini is a reservoir for species of Helicobacter., Raksawan Deenonpoe, Chariya Chomvarin, Chawalit Pairojkul, Yaowalux Chamgramol, Alex Loukas, Paul J. Brindley, and Banchob Sripa

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Inhibition of extracellular cyclophilins with cyclosporine analog and development of atherosclerosis in apolipoprotein E-deficient mice., Michael Ditiatkovski, Vijaya Neelisetti, Huanhuan Cui, Miroslav Malesevic, Gunter Fischer, Michael I. Bukrinsky, and Dmitri Sviridov

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Two potential hookworm DAF-16 target genes, SNR-3 and LPP-1: gene structure, expression profile, and implications of a cis-regulatory element in the regulation of gene expression, Xin Gao, Kevin Goggin, Camille Dowling, Jason Qian, and John Hawdon

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Expression profile of heat shock response factors during hookworm larval activation and parasitic development., Verena Gelmedin, Angela Delaney, Lucas Jennelle, and John M. Hawdon

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Estrogen-like metabolites and DNA-adducts in urogenital schistosomiasis-associated bladder cancer., Maria João Gouveia, Júlio Santos, Paul J. Brindley, Gabriel Rinaldi, Carlos Lopes, Lúcio L. Santos, José Manuel Correia da Costa, and Nuno Vale

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CD8+ T cell immunity in an encephalitis model of Toxoplasma gondii infection., SuJin Hwang and Imtiaz A. Khan

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Targeting extracellular cyclophilins ameliorates disease progression in experimental biliary atresia., Tatiana Iordanskaia, Miroslav Malesevic, Gunter Fischer, Tatiana Pushkarsky, Michael Bukrinsky, and Evan Nadler

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Evaluation of cytosine DNA methylation of the Biomphalaria glabratahe at shock protein 70 locus after biological and physiological stresses, Wannaporn Ittiprasert, Andre Miller, Matty Knight, Matt Tucker, and Michael H. Hsieh

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Gene function in schistosomes: recent advances toward a cure, Arnon D. Jurburg and Paul J. Brindley

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CD8+ T cell immune response against non-viral pathogens., Imtiaz A. Khan

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Susceptibility of Snails to Infection with Schistosomes is influenced by Temperature and Expression of Heat Shock Proteins., Matty Knight, O Elhelu, M Smith, Victoria Mann, Gabriel Rinaldi, Paul J. Brindley, and + 7 more

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Cellular immune correlates analysis of an HIV-1 preexposure prophylaxis trial., Peter J Kuebler, Megha L Mehrotra, J Jeff McConnell, Sara J Holditch, Brian I Shaw, Leandro F Tarosso, Kaitlyn S Leadabrand, Jeffrey M Milush, Vanessa A York, Rui André Saraiva Raposo, Rex G Cheng, Emily M Eriksson, Vanessa McMahan, David V Glidden, Stephen Shiboski, Robert M Grant, Douglas F Nixon, and Esper G Kallás

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HIV-1 gp120 T cell Responses Correspond to Infection Outcomes in the Global iPrEx Chemprophylaxis Trial., Peter J. Kuebler, Brian I. Shaw, Kaitlyn S. Leadabrand, Megha L. Mehrotra, Robert M. Grant, Esper G. Kallás, and Douglas F. Nixon

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Human T-lymphotropic virus 1, breastfeeding, and antiretroviral therapy., Fabio E Leal, Marcin Michniowski, and Douglas F Nixon

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Human Herpesvirus 6 as a Viral Trigger in Mesial Temporal Lobe Epilepsy., Emily C. Leibovitch and Steven Jacobson

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Lipid metabolism in patients infected with Nef-deficient HIV-1 strain., Hann Low, Lesley Cheng, Maria-Silvana Di Yacovo, Melissa J Churchill, Peter Meikle, Michael Bukrinsky, Andrew F Hill, and Dmitri Sviridov

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Apoptosis of cholangiocytes modulated by thioredoxin of carcinogenic liver fluke., Pitchaya Matchimakul, Gabriel Rinaldi, Sutas Suttiprapa, Victoria H. Mann, Anastas Popratiloff, Thewarach Laha, Rafael N. Pimenta, Christina J. Cochran, Sasithorn Kaewkes, Banchob Sripa, and Paul J Brindley

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IL-12 producing CD103+ CD11b-CD8+ DC are responsible for eliciting gut IEL response against E. cuniculi., Magali M Moretto, Danielle I Harrow, Teresa S Hawley, and Imtiaz A Khan

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Interleukin-12-producing CD103+ CD11b- CD8+ dendritic cells are responsible for eliciting gut intraepithelial lymphocyte response against Encephalitozoon cuniculi., Magali M. Moretto, Danielle I. Harrow, Teresa S. Hawley, and Imtiaz A. Khan

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Effector CD8 T cell immunity in microsporidial infection: a lone defense mechanism., Magali M. Moretto, Danielle I. Harrow, and Imtiaz A. Khan

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CD47 Promotes Protective Innate and Adaptive Immunity in a Mouse Model of Disseminated Candidiasis., Dhammika H. M. L. P. Navarathna, Erica V. Stein, Elizabeth C. Lessey-Morillon, Debasis Nayak, Gema Martin-Manso, and David D. Roberts

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Genome-wide characterization of microsatellites and marker development in the carcinogenic liver fluke Clonorchis sinensis., Thao T B Nguyen, Yuji Arimatsu, Sung-Jong Hong, Paul J. Brindley, David Blair, Thewarach Laha, and Banchob Sripa

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Test, treat, and cure., Douglas F. Nixon, Gary L. Simon, and Rui André Raposo

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Opisthorchiasis: An Overlooked Danger, Ludmila M. Ogorodova, Olga S. Fedorova, Banchob Sripa, Viatcheslav A. Mordvinov, Aleksei V. Katokhin, Paul J. Brindley, and The TOPIC Consortium

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Opisthorchiasis: an overlooked danger., Ludmila M Ogorodova, Olga S Fedorova, Banchob Sripa, Viatcheslav A Mordvinov, Aleksei V Katokhin, Jennifer Keiser, Peter Odermatt, Paul J. Brindley, Oleg A Mayboroda, Thirumalaisamy P Velavan, Maxim B Freidin, Alexey E Sazonov, Irina V Saltykova, Mariya Y Pakharukova, Yulia V Kovshirina, Kostas Kaloulis, Olga Y Krylova, and Maria Yazdanbakhsh

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Functional Analysis of the Unique Cytochrome P450 of the Liver Fluke Opisthorchis felineus., Mariya Y. Pakharukova, Valentin A. Vavilin, Banchob Sripa, Thewarach Laha, Paul J. Brindley, and Viatcheslav A. Mordvinov

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Suppression of Ov-grn-1 encoding granulin of Opisthorchis viverrini inhibits proliferation of biliary epithelial cells, A. Papatpremsiri, Michael J. Smout, Alex Loukas, Paul J. Brindley, Banchob Sripa, and Therawach Laha

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Of monkeys and men: immunomic profiling of sera from humans and non-human primates resistant to schistosomiasis reveals novel potential vaccine candidates., Mark S Pearson, Luke Becker, Patrick Driguez, Neil D Young, Soraya Gaze, Jeffrey M. Bethony, and +12 additional authors

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New tools for NTD vaccines: A case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74., Mark S Pearson, Amar R. Jariwala, Giovanni Abbenante, Jordan Plieskatt, David Wilson, Maria Elena Bottazzi, Peter J Hotez, Brian Keegan, Jeffrey M. Bethony, and Alex Loukas

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The Right Tool for the Job: Detection of Soil-Transmitted Helminths in Areas Co-endemic for Other Helminths, Maria V. Periago, Renata C. Diniz, Simone A. Pinto, Anna Yakovleva, Rodrigo Correa-Oliveira, David J. Diemert, and Jeffrey M. Bethony

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A microRNA profile associated with Opisthorchis viverrini-induced cholangiocarcinoma in tissue and plasma., Jordan Plieskatt, Gabriel Rinaldi, Yanjun Feng, Jin Peng, Samantha Easley, Xinying Jia, Jeremy Potriquet, Chawalit Pairojkul, Vajarabhongsa Bhudhisawasdi, Banchob Sripa, Paul J Brindley, Jeffrey Bethony, and Jason Mulvenna

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Antiviral gene expression in psoriasis., R. A. Raposo, R. Gupta, M. Abdel-Mohsen, M. Dimon, M. Debbaneh, W. Jiang, V. A. York, K. S. Leadabrand, G. Brown, M. Malakouti, S. Arron, P. J. Kuebler, J. J. Wu, S. K. Pillai, Douglas F. Nixon, and W. Liao

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Viability of developmental stages of Schistosoma mansoni quantified with xCELLigence worm real-time motility assay (xWORM)., Gabriel Rinaldi, Alex Loukas, Paul J. Brindley, Jeff T. Irelan, and Michael J. Smout

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Cytometric analysis, genetic manipulation and antibiotic selection of the snail embryonic cell line Bge from Biomphalaria glabrata, the intermediate host of Schistosoma mansoni., Gabriel Rinaldi, Hongbin Yan, Rafael Nacif-Pimenta, Pitchaya Matchimakul, Joanna Bridger, Victoria H. Mann, Michael J. Smout, Paul J. Brindley, and Matty Knight

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New Research Tools for Urogenital Schistosomiasis., Gabriel Rinaldi, Neil D. Young, Jared D. Honeycutt, Paul J. Brindley, Robin B. Gasser, and Michael H. Hsieh

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Levels of 8-OxodG Predict Hepatobiliary Pathology in Opisthorchis viverrini Endemic Settings in Thailand., Prasert Saichua, Anna Yakovleva, Christine Kamamia, Amar R. Jariwala, Paul J. Brindley, Jeffrey M. Bethony, and + 8 more

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Comparison of findings using ultrasonography and cystoscopy in urogenital schistosomiasis in a public health centre in rural Angola, Julio Santos, Jacinta Chaves, Heriberto Araujo, Nuno Vale, Jose Manuel Costa, Paul J. Brindley, Carlos Lopes, Jean Naples, Clive Shiff, Jorge Dupret, and Lucio Lara Santos

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Carcinogenic Parasite Secretes Growth Factor That Accelerates Wound Healing and Potentially Promotes Neoplasia., Michael J. Smout, Javier Sotillo, Thewarach Laha, Atiroch Papatpremsiri, Gabriel Rinaldi, Rafael N. Pimenta, Paul J. Brindley, and +11 more

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Immunodiagnosis of opisthorchiasis using parasite cathepsin F., Salma Teimoori, Yuji Arimatsu, Thewarach Laha, Sasithorn Kaewkes, Piya Sereerak, Sirikachorn Tangkawattana, Paul J. Brindley, and Banchob Sripa

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Intake of Erythrocytes Required for Reproductive Development of Female Schistosoma japonicum., Jipeng Wang, Shuqi Wang, Xiufeng Liu, Bin Xu, Riyi Chai, Pan Zhou, Chuan Ju, Jun Sun, Paul J. Brindley, and Wei Hu

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Advances in the Diagnosis of Human Opisthorchiasis: Development of Opisthorchis viverrini Antigen Detection in Urine, Chanika Worasith, Christine Kamamia, Anna Yakovleva, Kunyarat Duenngai, Chompunoot Wangboon, Jeffrey M. Bethony, and +8 additional authors

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An improved method for generating axenic entomopathogenic nematodes., Shruti Yadav, Upasana Shokal, Steven Forst, and Ioannis Eleftherianos

Submissions from 2014

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Elevated serum levels of interleukin-6 in endemic Burkitt lymphoma in Ghana, Peter Aka, Benjamin Emmanuel, Maria Candida Vila, Amar R. Jariwala, Francis Nkrumah, Maria V. Periago, Janet Neequaye, Christine Kiruthu, Paul H. Levine, Robert J. Biggar, Kishor Bhatia, Jeffrey M. Bethony, and Sam M. Mbulaiteye

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Differential spatial repositioning of activated genes in Biomphalaria glabrata snails infected with Schistosoma mansoni, Halime D. Arican-Goktas, Wannaporn Ittiprasert, Joanna M. Bridger, and Matty Knight

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Intrinsic TGF-β signaling promotes age-dependent CD8+ T cell polyfunctionality attrition., Rajarshi Bhadra, Magali M. Moretto, Julio C Castillo, Constantinos Petrovas, Sara Ferrando-Martinez, Upasana Shokal, Manuel Leal, Richard A Koup, Ioannis Eleftherianos, and Imtiaz A. Khan

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HIV-1 infection of macrophages induces retention of cholesterol transporter ABCA1 in the endoplasmic reticulum, Beda Brichacek, Christina Darwish, Anastas Popratiloff, Larisa Dubrovsky, and Michael I. Bukrinsky

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Schistosome and liver fluke derived catechol-estrogens and helminth associated cancers., José M. Correia da Costa, Nuno Vale, Maria J. Gouveia, Mónica C. Botelho, Banchob Sripa, Lúcio L. Santos, Júlio H. Santos, Gabriel Rinaldi, and Paul J. Brindley

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HIV protein NEF causes dyslipidemia and formation of foam cells in mouse models of atherosclerosis, Huanhuan L. Cui, Michael Ditiatkovski, Rajitha Kesani, Yuri V. Bobryshev, Yingying Liu, Matthias Geyer, Nigora Mukhamedova, Michael I. Bukrinsky, and Dmitri Sviridov

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Prion infection impairs cholesterol metabolism in neuronal cells, Huanhuan L. Cui, Belinda Guo, Benjamin Scicluna, Bradley M. Coleman, Victoria A. Lawson, Laura Ellett, Peter J. Meikle, Michael I. Bukrinsky, Nigora Mukhamedova, Dmitri Sviridov, and Andrew F. Hill

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RNA interference in Fasciola hepatica newly excysted juveniles: Long dsRNA induces more persistent silencing than siRNA, Nicolas Dell'Oca, Tatiana Basika, Ileana Corvo, Estella Castillo, Paul J. Brindley, Gabriel Rinaldi, and Jose Tort

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Effectiveness of a novel immunogenic nanoparticle platform for Toxoplasma peptide vaccine in HLA transgenic mice, Kamal El Bissati, Ying Zhou, Debleena Dasgupta, Drew Cobb, Jitender P. Dubey, Peter Burkhard, David E. Lanar, and Rima McLeod

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Strengthening neglected tropical disease research through enhancing research-site capacity: An evaluation of a novel web application to facilitate research collections, Tanzin Furtado, Samuel Franzen, Francois van Loggerenberg, Gwenaelle Carn, Shannon Grahek, Megan McBride, Maureen Power, Barbara Savarese, Margaret Ann Snowden, Gwynn Stevens, Almarie Uys, and Trudie Lang

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Immunology of experimental and natural human hookworm infection, S. Gaze, Jeffrey M. Bethony, and Maria V. Periago

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An immunomics approach to schistosome antigen discovery: Antibody signatures of naturally resistant and chronically infected individuals from endemic areas, Soraya Gaze, Patrick Driguez, Mark S. Pearson, Tiago Mendes, Denise L. Doolan, Jeffrey M. Bethony, and +14 additional authors

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Novel neuroprotective GSK-3β inhibitor restricts Tat-mediated HIV-1 replication, Irene Guendel, Sergey N. Iordanskiy, Rachel Van Duyne, Kylene Kehn-Hall, Mohammed Saifuddin, Ravi Das, Elizabeth Jaworski, Gavin C. Sampey, Svetlana Senina, Leonard Shultz, Aarthi Narayanan, Chen Hao, Benjamin Lepene, Chen Zeng, and Fatah Kashanchi

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Diminished humoral responses against and reduced gene expression levels of human endogenous retrovirus-K (HERV-K) in psoriasis, Rashmi Gupta, Henri-Alexandre Michaud, Xue Zeng, Maya Debbaneh, Sarah T. Arron, R. Brad Jones, Christopher E. Ormsby, Douglas F. Nixon, and Wilson Liao

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Controlling soil transmitted helminths: Time to think inside the box?, John Hawdon

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Medicine. Halting harmful helminths, Karl F. Hoffmann, Paul J. Brindley, and Matthew Berriman

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The use of nanotrap particles technology in capturing HIV-1 virions and viral proteins from infected cells, Elizabeth Jaworski, Mohammed Saifuddin, Gavin C. Sampey, Nazly Shafagati, Rachel Van Duyne, Sergey N. Iordanskiy, Kylene Kehn-Hall, Lance Liotta, Emanuel F. Petricoin III, Mary Young, and Benjamin Lepene

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HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexin., Lucas Jennelle, Ruth Hunegnaw, Larisa Dubrovsky, Tatiana Pushkarsky, Michael L Fitzgerald, Dmitri Sviridov, Anastas Popratiloff, Beda Brichacek, and Michael Bukrinsky