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Submissions from 2024

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Towards an HIV cure: one cell at a time, Alberto Bosque

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Towards an HIV cure: one cell at a time, Alberto Bosque

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Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site, Tom G. Caniels, Max Medina-Ramìrez, Shiyu Zhang, Sven Kratochvil, Yuejiao Xian, Ja-Hyun Koo, Ronald Derking, Jakob Samsel, Jelle van Schooten, Simone Pecetta, Edward Lamperti, Meng Yuan, María Ríos Carrasco, Iván Del Moral Sánchez, Joel D. Allen, Joey H. Bouhuijs, Anila Yasmeen, Thomas J. Ketas, Jonne L. Snitselaar, Tom P. Bijl, Isabel Cuella Martin, Jonathan L. Torres, Albert Cupo, Lisa Shirreff, Kenneth Rogers, Rosemarie D. Mason, Mario Roederer, Kelli M. Greene, Hongmei Gao, Catarina Mendes Silva, Isabel J. Baken, and Ming Tian

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Targeting the DHX9 RNA Helicase to Induce Antitumor Immunity in Small-Cell Lung Cancer, Katherine B. Chiappinelli

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Ascaris Mouse Model Protocols: Advancing Research on Larval Ascariasis Biology, Camila de Almeida Lopes, Jianbin Wang, Benjamin Liffner, Sabrina Absalon, and Pedro H. Gazzinelli-Guimaraes

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Human immunoglobulin gene allelic variation impacts germline-targeting vaccine priming, Allan C. deCamp, Martin M. Corcoran, William J. Fulp, Jordan R. Willis, Christopher A. Cottrell, Daniel L. Bader, Oleksandr Kalyuzhniy, David J. Leggat, Kristen W. Cohen, Ollivier Hyrien, Sergey Menis, Greg Finak, Lamar Ballweber-Fleming, Abhinaya Srikanth, Jason R. Plyler, Farhad Rahaman, Angela Lombardo, Vincent Philiponis, Rachael E. Whaley, Aaron Seese, Joshua Brand, Alexis M. Ruppel, Wesley Hoyland, Celia R. Mahoney, Alberto Cagigi, Alison Taylor, David M. Brown, David R. Ambrozak, Troy Sincomb, Tina-Marie Mullen, Janine Maenza, and Orpheus Kolokythas

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Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased affinity to Fcγ receptors during acute SHIV infection, Joana Dias, Giulia Fabozzi, Slim Fourati, Xuejun Chen, Cuiping Liu, David R. Ambrozak, Amy Ransier, Farida Laboune, Jianfei Hu, Wei Shi, Kylie March, Anna A. Maximova, Stephen D. Schmidt, Jakob Samsel, Chloe A. Talana, Keenan Ernste, Sung Hee Ko, Margaret E. Lucas, Pierce E. Radecki, Kristin L. Boswell, Yoshiaki Nishimura, John-Paul Todd, Malcolm A. Martin, Constantinos Petrovas, Eli A. Boritz, Nicole A. Doria-Rose, Daniel C. Douek, Rafick-Pierre Sékaly, Jeffrey D. Lifson, Mangaiarkarasi Asokan, Lucio Gama, and John R. Mascola

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Internet-based, continuously available Narcotics Anonymous meetings: a new resource for access to Twelve Step support for abstinence, Marc Galanter, William L. White, Brooke Hunter, and Jag Khalsa

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Assessing de novo parasite genomes assembled using only Oxford Nanopore Technologies MinION data, Kaylee S. Herzog, Rachel Wu, John M. Hawdon, Peter Nejsum, and Joseph R. Fauver

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HIV-1 latency reversal and immune enhancing activity of IL-15 is not influenced by sex hormones, Carissa S. Holmberg, Callie Levinger, Marie Abongwa, Cristina Ceriani, Nancie M. Archin, Marc Siegel, Mimi Ghosh, and Alberto Bosque

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HIV-1 latency reversal and immune enhancing activity of IL-15 is not influenced by sex hormones, Carissa S. Holmberg, Callie Levinger, Marie Abongwa, Cristina Ceriani, Nancie Archin, Marc Siegel, Mimi Ghosh, and Alberto Bosque

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The HIV latency reversing agent HODHBt inhibits the phosphatases PTPN1 and PTPN2, J Natalie Howard, Thomas D. Zaikos, Callie Levinger, Esteban Rivera, Elyse K. McMahon, Carissa S. Holmberg, Joshua Terao, Marta Sanz, Dennis C. Copertino, Weisheng Wang, Natalia Soriano-Sarabia, R Brad Jones, and Alberto Bosque

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Multiplexed CRISPR-Cas9 protocol for large transgene integration into the Schistosoma mansoni genome, Wannaporn Ittiprasert, Max M. Moescheid, Victoria H. Mann, and Paul J. Brindley

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Multiplexed CRISPR-Cas9 protocol for large transgene integration into the Schistosoma mansoni genome, Wannaporn Ittiprasert, Max M. Moescheid, Victoria H. Mann, and Paul J. Brindley

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Elevated homocysteine levels may moderate and mediate the association between HIV and cognitive impairment among middle-aged and older adults in an underserved population in Baltimore, Maryland, Hong Lai, Glenn Treisman, David D. Celentano, Gary Gerstenblith, Raul N. Mandler, Jag Khalsa, Man Charurat, Shenghan Lai, and Godfrey Pearson

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Therapeutic targeting of DNA methylation alterations in cancer, Abigail V. Lee, Kevin A. Nestler, and Katherine B. Chiappinelli

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Homocysteine modifies the association of coronary stenosis and HIV infection in an inner city African American population, Thorsten M. Leucker, Tarek Harb, Gary Gerstenblith, David D. Celentano, Efthymios Ziogos, Glenn Treisman, Raul N. Mandler, Jag Khalsa, Man Charurat, Shenghan Lai, and Hong Lai

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Dual role of circulating and mucosal Vδ1 T cells in the control of and contribution to persistent HIV-1 infection, Brendan T. Mann, Marta Sanz, Matthew Clohosey, Kayley Langlands, Alisha Chitrakar, Carles Moreno, Joana Vitalle, Marie Anne Iannone, Ezequiel Ruiz-Mateos, Claire Deleage, Marc Siegel, and Natalia Soriano-Sarabia

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Altered larval activation response associated with multidrug resistance in the canine hookworm Ancylostoma caninum, Elise L. McKean, Emilia Grill, Young-Jun Choi, Makedonka Mitreva, Damien M. O'Halloran, and John M. Hawdon

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Extracellular vesicles produced by HIV-1 Nef-expressing cells induce myelin impairment and oligodendrocyte damage in the mouse central nervous system, Jessica K. Schenck, Molly T. Karl, Cheryl Clarkson-Paredes, Ashley Bastin, Tatiana Pushkarsky, Beda Brichacek, Robert H. Miller, and Michael I. Bukrinsky

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Parallel HIV-1 evolutionary dynamics in humans and rhesus macaques who develop broadly neutralizing antibodies, Kai S. Shimagaki, Rebecca M. Lynch, and John P. Barton

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An Old Drug Learning New Tricks: A REPRIEVE for Cardiovascular Disease in HIV Infection, Dmitri Sviridov and Michael Bukrinsky

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Enhancing the opportunities for cholangiocarcinoma precision therapy, Reka Toth, Paul J. Brindley, and Javier Vaquero

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HIV-1 Nef is carried on the surface of extracellular vesicles, Christophe Vanpouille, Beda Brichacek, Tatiana Pushkarsky, Larisa Dubrovsky, Wendy Fitzgerald, Nigora Mukhamedova, Sofia Garcia-Hernandez, Doreen Matthies, Anastas Popratiloff, Dmitri Sviridov, Leonid Margolis, and Michael Bukrinsky

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Development of LIBRA-seq for the guinea pig model system as a tool for the evaluation of antibody responses to multivalent HIV-1 vaccines, Matthew J. Vukovich, Nagarajan Raju, Prudence Kgagudi, Nelia P. Manamela, Alexandra A. Abu-Shmais, Kathryn R. Gripenstraw, Perry T. Wasdin, Xiaoying Shen, Bridget Dwyer, Jumana Akoad, Rebecca M. Lynch, David C. Montefiori, Simone I. Richardson, Penny L. Moore, and Ivelin S. Georgiev

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Autologous neutralizing antibody responses after antiretroviral therapy in acute and early HIV-1, Gregory D. Whitehill, Jaimy Joy, Francesco E. Marino, Ryan J. Krause, Suvadip Mallick, Hunter M. Courtney, Kyewon Park, John W. Carey, Rebecca Hoh, Heather Hartig, Vivian Pae, Sannidhi Sarvadhavabhatla, Maria Sophia Donaire, Steven G. Deeks, Rebecca M. Lynch, Sulggi A. Lee, and Katharine J. Bar

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Proteomic profiling of oleamide-mediated polarization in a primary human monocyte-derived tumor-associated macrophages (TAMs) model: a functional analysis, Prapakorn Wisitpongpun, Watunyoo Buakaew, Sutatip Pongcharoen, Napaporn Apiratmateekul, Pachuen Potup, Krai Daowtak, Sucheewin Krobthong, Yodying Yingchutrakul, Paul J. Brindley, and Kanchana Usuwanthim

Submissions from 2023

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Meeting report: transposable elements at the crossroads of evolution, health and disease 2023, Irina R. Arkhipova, Kathleen H. Burns, Katherine B. Chiappinelli, Edward B. Chuong, Clement Goubert, Alba Guarné, Amanda M. Larracuente, E Alice Lee, and Henry L. Levin

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Proceedings of the inaugural Dark Genome Symposium: November 2022, Jef D. Boeke, Kathleen H. Burns, Katherine B. Chiappinelli, Marie Classon, John M. Coffin, Daniel D. DeCarvalho, Joseph D. Dukes, Benjamin Greenbaum, George Kassiotis, Sarah K. Knutson, Arnold J. Levine, Avindra Nath, Sophie Papa, Daniel Rios, John Sedivy, and David T. Ting

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Neurogenetics and Epigenetics of Loneliness, Abdalla Bowirrat, Igor Elman, Catherine A. Dennen, Marjorie C. Gondré-Lewis, Jean Lud Cadet, Jag Khalsa, David Baron, Diwanshu Soni, Mark S. Gold, Thomas J. McLaughlin, Debasis Bagchi, Eric R. Braverman, Mauro Ceccanti, Panayotis K. Thanos, Edward Justin Modestino, Keerthy Sunder, Nicole Jafari, Foojan Zeine, Rajendra D. Badgaiyan, Debmalya Barh, Milan Makale, Kevin T. Murphy, and Kenneth Blum

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AP-1/c-Fos supports SIV and HIV-1 latency in CD4 T cells infected, Viviana Cobos Jiménez, Aviva Geretz, Andrey Tokarev, Philip K. Ehrenberg, Selase Deletsu, Kawthar Machmach, Prakriti Mudvari, J Natalie Howard, Amanda Zelkoski, Dominic Paquin-Proulx, Gregory Q. Del Prete, Caroline Subra, Eli A. Boritz, Alberto Bosque, Rasmi Thomas, and Diane L. Bolton

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A first-in-human germline-targeting HIV nanoparticle vaccine induced broad and publicly targeted helper T cell responses, Kristen W. Cohen, Stephen C. De Rosa, William J. Fulp, Allan C. deCamp, Andrew Fiore-Gartland, Celia R. Mahoney, Sarah Furth, Josh Donahue, Rachael E. Whaley, Lamar Ballweber-Fleming, Aaron Seese, Katharine Schwedhelm, Daniel Geraghty, Greg Finak, Sergey Menis, David J. Leggat, Farhad Rahaman, Angela Lombardo, Bhavesh R. Borate, Vincent Philiponis, Janine Maenza, David Diemert, Orpheus Kolokythas, Nadia Khati, Jeffrey Bethony, Ollivier Hyrien, Dagna S. Laufer, Richard A. Koup, Adrian B. McDermott, William R. Schief, and M Juliana McElrath

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The latency reversing agent HODHBt synergizes with IL-15 to enhance cytotoxic function of HIV-specific CD8+ T-cells, Dennis C. Copertino, Carissa S. Holmberg, Jared Weiler, Adam R. Ward, J Natalie Howard, Callie Levinger, Alina Ps Pang, Michael J. Corley, Friederike Dündar, Paul Zumbo, Doron Betel, Rajesh T. Gandhi, Deborah K. McMahon, Ronald J. Bosch, Noemi Linden, Bernard J. Macatangay, Joshua C. Cyktor, Joseph J. Eron, John W. Mellors, Colin Kovacs, Erica Benko, Alberto Bosque, and R Brad Jones

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The latency-reversing agent HODHBt synergizes with IL-15 to enhance cytotoxic function of HIV-specific T cells, Dennis C. Copertino, Carissa S. Holmberg, Jared Weiler, Adam R. Ward, J Natalie Howard, Callie Levinger, Alina Ps Pang, Michael J. Corley, Friederike Dündar, Paul Zumbo, Doron Betel, Rajesh T. Gandhi, Deborah K. McMahon, Ronald J. Bosch, Noemi Linden, Bernard J. Macatangay, Joshua C. Cyktor, Joseph J. Eron, John W. Mellors, Colin Kovacs, Erika Benko, Alberto Bosque, and R Brad Jones

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Transfusion-transmitted Babesia spp.: a changing landscape of epidemiology, regulation, and risk mitigation, Steven J. Drews, Anne M. Kjemtrup, Peter J. Krause, Grayson Lambert, David A. Leiby, Antoine Lewin, Sheila F. O'Brien, Christian Renaud, Laura Tonnetti, and Evan M. Bloch

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Transfusion-transmitted Babesia spp.: a changing landscape of epidemiology, regulation, and risk mitigation, Steven J. Drews, Anne M. Kjemtrup, Peter J. Krause, Grayson Lambert, David A. Leiby, Antoine Lewin, Sheila F. O'Brien, Christian Renaud, Laura Tonnetti, and Evan M. Bloch

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Severe autoimmune lymphoproliferative syndrome phenotype in a pediatric patient with a germline FAS gene variant, Alexandra Dreyzin, Jinjun Cheng, David Leitenberg, and Yaser Diab

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State of the science and future directions for research on HIV and cancer: Summary of a joint workshop sponsored by IARC and NCI, Eric A. Engels, Meredith S. Shiels, Ruanne V. Barnabas, Julia Bohlius, Paul Brennan, Jessica Castilho, Stephen J. Chanock, Megan A. Clarke, Anna E. Coghill, Jean-Damien Combes, Scott Dryden-Peterson, Gypsyamber D'Souza, Satish Gopal, Antoine Jaquet, Kathryn Lurain, Alain Makinson, Jeffrey Martin, Mazvita Muchengeti, Robert Newton, Fred Okuku, Jackson Orem, Joel M. Palefsky, Ramya Ramaswami, Hilary A. Robbins, Keith Sigel, Sylvia Silver, Gita Suneja, Robert Yarchoan, and Gary M. Clifford

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IL-15 and N-803 for HIV Cure Approaches, J Natalie Howard and Alberto Bosque

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Targeted insertion and reporter transgene activity at a gene safe harbor of the human blood fluke, Schistosoma mansoni, Wannaporn Ittiprasert, Max F. Moescheid, Cristian Chaparro, Victoria H. Mann, Thomas Quack, Rutchanee Rodpai, André Miller, Prapakorn Wisitpongpun, Watunyoo Buakaew, Margaret Mentink-Kane, Sarah Schmid, Anastas Popratiloff, Christoph G. Grevelding, Christoph Grunau, and Paul J. Brindley

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Oncogenic Transformation Drives DNA Methylation Loss and Transcriptional Activation of Transposable Element Loci, Tomas Kanholm, Uzma Rentia, Melissa Hadley, Jennifer A. Karlow, Olivia L. Cox, Noor Diab, Matthew L. Bendall, Tyson Dawson, James I. McDonald, Wenbing Xie, Keith A. Crandall, Kathleen H. Burns, Stephen B. Baylin, Hariharan Easwaran, and Katherine B. Chiappinelli

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Cocaine Use May Moderate the Associations of HIV and Female Sex with Neurocognitive Impairment in a Predominantly African American Population Disproportionately Impacted by HIV and Substance Use, Hong Lai, David D. Celentano, Glenn Treisman, Jag Khalsa, Gary Gerstenblith, Bryan Page, Raul N. Mandler, Yihong Yang, Betty Salmeron, Sandeepan Bhatia, Shaoguang Chen, Shenghan Lai, Karl Goodkin, and Man Charurat

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Elevated homocysteine levels may moderate and mediate the association between HIV and cognitive impairment among middle-aged and older adults in an underserved population in Baltimore, Maryland, Hong Lai, Glenn Treisman, David D. Celentano, Gary Gerstenblith, Raul N. Mandler, Jag Khalsa, Man Charurat, Shenghan Lai, and Godfrey Pearson

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Comparative transcriptomics from intestinal cells of permissive and non-permissive hosts during infection reveals unique signatures of protection and host specificity, Andrea Langeland, Emilia Grill, Amol C. Shetty, Damien M. O'Halloran, and John M. Hawdon

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Comparative transcriptomics from intestinal cells of permissive and non-permissive hosts during infection reveals unique signatures of protection and host specificity, Andrea Langeland, Emilia Grill, Amol C. Shetty, Damien M. O'Halloran, and John M. Hawdon

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Immunity mediates host specificity in the human hookworm, Andrea Langeland, Elise L. McKean, Damien M. O'Halloran, and John M. Hawdon

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Development of screening assays for use of broadly neutralizing antibodies in people with HIV, Rebecca M. Lynch and Katharine J. Bar

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Development of screening assays for use of broadly neutralizing antibodies in people with HIV, Rebecca M. Lynch and Katharine J. Bar

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Inhibition of carbonic anhydrase using aspirin is a novel method to block schistosomiasis infection of the parasitic trematode, Schistosoma mansoni, in the intermediate snail host, Biomphalaria glabrata, Simone Parn, Gabriela Lewis, and Matty Knight

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Polio eradication efforts: Above all, do no harm, Stanley A. Plotkin and Konstantin Chumakov

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Bacterial contact induces polar plug disintegration to mediate whipworm egg hatching, Amicha Robertson, Joseph Sall, Mericien Venzon, Janet J. Olivas, Xuhui Zheng, Michael Cammer, Noelle Antao, Chunyi Zhou, Joseph C. Devlin, Rafaela Saes Thur, Jeffrey Bethony, Peter Nejsum, Bo Shopsin, Victor J. Torres, Feng-Xia Liang, and Ken Cadwell

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Tetraspanins from the liver fluke Opisthorchis viverrini stimulate cholangiocyte migration and inflammatory cytokine production, Apisit Ruangsuwast, Michael J. Smout, Paul J. Brindley, Alex Loukas, Thewarach Laha, and Sujittra Chaiyadet

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Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes, Rajeshwer S. Sankhala, Vincent Dussupt, Gina Donofrio, Gregory D. Gromowski, Rafael A. De La Barrera, Rafael A. Larocca, Letzibeth Mendez-Rivera, Anna Lee, Misook Choe, Weam Zaky, Grace Mantus, Jaime L. Jensen, Wei-Hung Chen, Neelakshi Gohain, Hongjun Bai, Michael K. McCracken, Rosemarie D. Mason, David Leggat, Bonnie M. Slike, Ursula Tran, Ningbo Jian, Peter Abbink, Rebecca Peterson, Eric Araujo Mendes, Rafael Freitas de Oliveira Franca, Guilherme Amaral Calvet, Ana Maria Bispo de Filippis, Adrian McDermott, Mario Roederer, Mayda Hernandez, Amie Albertus, and Edgar Davidson

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Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1, Marta Sanz, Ann Marie Weideman, Adam R. Ward, Matthew L. Clohosey, Susana Garcia-Recio, Sara R. Selitsky, Brendan T. Mann, Marie Anne Iannone, Chloe P. Whitworth, Alisha Chitrakar, Carolina Garrido, Jennifer Kirchherr, Alisha R. Coffey, Yi-Hsuan Tsai, Shahryar Samir, Yinyan Xu, Dennis Copertino, Alberto Bosque, Brad R. Jones, Joel S. Parker, Michael G. Hudgens, Nilu Goonetilleke, and Natalia Soriano-Sarabia

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Ultrasound-guided lymph node fine-needle aspiration for evaluating post-vaccination germinal center responses in humans, Larissa L. Scholte, David J. Leggat, Kristen W. Cohen, Lara Hoeweler, Guacyara C. Erwin, Farhard Rahaman, Angela Lombardo, Vincent Philiponis, Dagna S. Laufer, Heather Siefers, Alexis M. Ruppel, Joshua Brand, Janine Maenza, Rhi Bronson, Madhu Prabhakaran, Jalen Jean-Baptiste, Orpheus Kolokythas, Aimee A. Desrosiers, Caroline K. Thoreson, Antje Heit, Nadia J. Khati, Elissa Malkin, M Juliana McElrath, Adrian B. McDermott, William R. Schief, David Diemert, and Jeffrey M. Bethony

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Diagnosis and monitoring of virus-associated cancer using cell-free DNA, Larissa Ls Scholte, Jeffrey M. Bethony, and Rena R. Xian

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Diagnosis and monitoring of virus-associated cancer using cell-free DNA, Larissa Ls Scholte, Jeffrey M. Bethony, and Rena R. Xian

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The AIDS and Cancer Specimen Resource (ACSR): HIV malignancy specimens and data available at no cost, Sylvia Silver and Monika Schmelz

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Neuro-HIV-New insights into pathogenesis and emerging therapeutic targets, Dmitri Sviridov and Michael Bukrinsky

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Excretory/Secretory Proteome of Females and Males of the Hookworm, Samuel C. Uzoechi, Bruce A. Rosa, Kumar Sachin Singh, Young-Jun Choi, Bethany K. Bracken, Paul J. Brindley, R Reid Townsend, Robert Sprung, Bin Zhan, Maria-Elena Bottazzi, John M. Hawdon, Yide Wong, Alex Loukas, Sergej Djuranovic, and Makedonka Mitreva

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Development of LIBRA-seq for the guinea pig model system as a tool for the evaluation of antibody responses to multivalent HIV-1 vaccines, Matthew J. Vukovich, Nagarajan Raju, Prudence Kgagudi, Nelia P. Manamela, Alexandra A. Abu-Shmais, Kathryn R. Gripenstraw, Perry T. Wasdin, Xiaoying Shen, Bridget Dwyer, Jumana Akoad, Rebecca M. Lynch, David C. Montefiori, Simone I. Richardson, Penny L. Moore, and Ivelin S. Georgiev

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Protein Exaptation by Endogenous Retroviral Elements Shapes Tumor Cell Senescence and Downstream Immune Signaling, Reddick R. Walker and Katherine B. Chiappinelli

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Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility, Ruby White, Javier Sotillo, María Eugenia Ancarola, Anne Borup, Anders Toftegaard Boysen, Paul J. Brindley, Edit I. Buzás, Serena Cavallero, Sujittra Chaiyadet, Iain W. Chalmers, Marcela A. Cucher, Maude Dagenais, Chelsea N. Davis, Eileen Devaney, Maria A. Duque-Correa, Ramon Marc Eichenberger, Santiago Fontenla, Thomas A. Gasan, Cornelis H. Hokke, Maja Kosanovic, Marije E. Kuipers, Thewarach Laha, Alex Loukas, Rick M. Maizels, Antonio Marcilla, Hynek Mazanec, Russell M. Morphew, Kyriaki Neophytou, Linh Thuy Nguyen, Esther Nolte-'t Hoen, Michael Povelones, and Mark W. Robinson

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Anticipating HIV viral escape - resistance to active and passive immunization, Carolyn Williamson, Rebecca M. Lynch, and Penny L. Moore

Submissions from 2022

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HIV, psychological resilience, and substance misuse during the COVID-19 pandemic: A multi-cohort study, Marianna K. Baum, Javier A. Tamargo, Janet Diaz-Martinez, Ivan Delgado-Enciso, Christina S. Meade, Gregory D. Kirk, Shruti H. Mehta, Richard Moore, Michele D. Kipke, Steven J. Shoptaw, Brian Mustanski, Raul N. Mandler, Jag H. Khalsa, Suzanne Siminski, Marjan Javanbakht, and Pamina M. Gorbach

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Editorial: Lipids and Inflammation in Health and Disease, Evgeny Bezsonov, Vasily Sukhorukov, Michael Bukrinsky, and Alexander Orekhov

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Celebrating a year of clinical and translational research in Blood Advances, Catherine M. Bollard and Andrew Weyrich

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The Cultured T Model of HIV Latency, Alberto Bosque

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Silencing of Tetraspanin Gene Expression Results in Reduced Secretion of Extracellular Vesicles, Sujittra Chaiyadet, Javier Sotillo, Watchara Krueajampa, Sophita Thongsen, Michael Smout, Paul J. Brindley, Thewarach Laha, and Alex Loukas

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Silencing of Tetraspanin Gene Expression Results in Reduced Secretion of Extracellular Vesicles, Sujittra Chaiyadet, Javier Sotillo, Watchara Krueajampa, Sophita Thongsen, Michael Smout, Paul J. Brindley, Thewarach Laha, and Alex Loukas

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Knockout of liver fluke granulin, Ov-grn-1, impedes malignant transformation during chronic infection with Opisthorchis viverrini, Sujittra Chaiyadet, Sirikachorn Tangkawattana, Michael J. Smout, Wannaporn Ittiprasert, Victoria H. Mann, Raksawan Deenonpoe, Patpicha Arunsan, Alex Loukas, Paul J. Brindley, and Thewarach Laha

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IL-27 induces IFN/STAT1-dependent genes and enhances function of TIGIT HIVGag-specific T cells, Jie Cheng, Timothy G. Myers, Callie Levinger, Princy Kumar, Jai Kumar, Bruktawit A. Goshu, Alberto Bosque, and Marta Catalfamo

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Inhibiting DNA methylation improves antitumor immunity in ovarian cancer, Katherine B. Chiappinelli and Stephen B. Baylin

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Safety and immunogenicity of the Na-APR-1 hookworm vaccine in infection-naïve adults, David J. Diemert, Maria Zumer, Doreen Campbell, Shannon Grahek, Guangzhao Li, Jin Peng, Maria Elena Bottazzi, Peter Hotez, and Jeffrey Bethony

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Safety and immunogenicity of the Na-APR-1 hookworm vaccine in infection-naïve adults, David J. Diemert, Maria Zumer, Doreen Campbell, Shannon Grahek, Guangzhao Li, Jin Peng, Maria Elena Bottazzi, Peter Hotez, and Jeffrey Bethony

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Climate change and parasitic risk to the blood supply, Steven J. Drews, Silvano Wendel, David A. Leiby, Laura Tonnetti, Ines Ushiro-Lumb, Sheila F. O'Brien, Ryanne W. Lieshout-Krikke, and Evan M. Bloch

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Extracellular vesicles carrying HIV-1 Nef induce long-term hyperreactivity of myeloid cells, Larisa Dubrovsky, Beda Brichacek, N M. Prashant, Tatiana Pushkarsky, Nigora Mukhamedova, Andrew J. Fleetwood, Yangsong Xu, Dragana Dragoljevic, Michael Fitzgerald, Anelia Horvath, Andrew J. Murphy, Dmitri Sviridov, and Michael I. Bukrinsky

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Transposable element regulation and expression in cancer, Erin E. Grundy, Noor Diab, and Katherine B. Chiappinelli

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Cocaine use associated gut permeability and microbial translocation in people living with HIV in the Miami Adult Study on HIV (MASH) cohort, Jacqueline Hernandez, Javier A. Tamargo, Sabrina Sales Martinez, Haley R. Martin, Adriana Campa, Rafick-Pierre Sékaly, Rebeka Bordi, Kenneth E. Sherman, Susan D. Rouster, Heidi L. Meeds, Jag H. Khalsa, Raul N. Mandler, Shenghan Lai, and Marianna K. Baum

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Culturing and Genetically Manipulating Entomopathogenic Nematodes, Christa Heryanto, Ramesh Ratnappan, Damien M. O'Halloran, John M. Hawdon, and Ioannis Eleftherianos

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THE GENERATION AND APPLICATION OF ANTIGEN-SPECIFIC T CELL THERAPIES FOR CANCER AND VIRAL-ASSOCIATED DISEASE, Amy B. Hont, Allison B. Powell, Danielle K. Sohai, Izabella K. Valdez, Maja Stanojevic, Ashley E. Geiger, Kajal Chaudhary, Ehsan K. Dowlati, Catherine M. Bollard, and Conrad Russell Cruz

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Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production, Benjamin J. Hulme, Kathrin K. Geyer, Josephine E. Forde-Thomas, Gilda Padalino, Dylan W. Phillips, Wannaporn Ittiprasert, Shannon E. Karinshak, Victoria H. Mann, Iain W. Chalmers, Paul J. Brindley, Cornelis H. Hokke, and Karl F. Hoffmann

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RNA-Guided Cas12a- and Cas9-Catalyzed Knockout and Homology Directed Repair of the Omega-1 Locus of the Human Blood Fluke,, Wannaporn Ittiprasert, Chawalit Chatupheeraphat, Victoria H. Mann, Wenhui Li, André Miller, Taiwo Ogunbayo, Kenny Tran, Yousef N. Alrefaei, Margaret Mentink-Kane, and Paul J. Brindley

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Palatal morphology predicts the paleobiology of early salamanders, Jia Jia, Guangzhao Li, and Ke-Qin Gao

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Review: Cannabinoids as Medicinals, Jag H. Khalsa, Gregory Bunt, Kenneth Blum, Sanjay B. Maggirwar, Marc Galanter, and Marc N. Potenza

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Immune responses to Toxoplasma gondii, Imtiaz A. Khan and Magali Moretto

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Nfkbid-mediated humoral immunity during secondary toxoplasmosis, Imtiaz A. Khan and Magali Moretto

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Human immunodeficiency virus-1 Tat exerts its neurotoxic effects by downregulating Sonic hedgehog signaling, Irfan A. Khan, Arthur H. Worrad, Meera V. Singh, Sanjay B. Maggirwar, and Vir B. Singh

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Hit-and-Run Epigenetic Editing for Vectors of Snail-Borne Parasitic Diseases, Nelia Luviano, David Duval, Wannaporn Ittiprasert, Jean-Francois Allienne, Geneviève Tavernier, Cristian Chaparro, Celine Cosseau, and Christoph Grunau

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Short Communication: A Pilot Study of the Effects of Losartan Versus Placebo on Pneumoproteins in HIV: A Secondary Analysis of a Randomized Double Blind Study, David M. MacDonald, Gary Collins, Chris H. Wendt, Julian Wolfson, Russell P. Tracy, Frank Rhame, Steven Deeks, Stacey A. Rizza, Zelalem Temesgen, Caryn Morse, Angelike P. Liappis, Irini Sereti, Jason V. Baker, and Ken M. Kunisaki

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Infection of Endothelial Cells by Dengue Virus Induces ROS Production by Different Sources Affecting Virus Replication, Cellular Activation, Death and Vascular Permeability, Lana Monteiro Meuren, Elisa Beatriz Prestes, Michelle Premazzi Papa, Luiza Rachel de Carvalho, Yasmin Mucunã Mustafá, Leandro Silva da Costa, Andrea T. Da Poian, Marcelo Torres Bozza, and Luciana Barros Arruda

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The Persistence of HIV Diversity, Transcription, and Nef Protein in Kaposi's Sarcoma Tumors during Antiretroviral Therapy, David J. Nolan, Rebecca Rose, Rongzhen Zhang, Alan Leong, Gary B. Fogel, Larissa L. Scholte, Jeffrey M. Bethony, Paige Bracci, Susanna L. Lamers, and Michael S. McGrath

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Platelet-Released Factors: Their Role in Viral Disease and Applications for Extracellular Vesicle (EV) Therapy, Brita Ostermeier, Natalia Soriano-Sarabia, and Sanjay B. Maggirwar

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Executable models of immune signaling pathways in HIV-associated atherosclerosis, Mukta G. Palshikar, Rohith Palli, Alicia Tyrell, Sanjay Maggirwar, Giovanni Schifitto, Meera V. Singh, and Juilee Thakar

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Transgenesis in parasitic helminths: a brief history and prospects for the future, M J. Quinzo, M J. Perteguer, P J. Brindley, A Loukas, and J Sotillo

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Pharmacological Targeting of Sphingosine Kinases Impedes HIV-1 Infection of CD4 T Cells through SAMHD1 Modulation, Rachel S. Resop and Alberto Bosque

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Pharmacological Targeting of Sphingosine Kinases Impedes HIV-1 Infection of CD4 T Cells through SAMHD1 Modulation, Rachel S. Resop and Alberto Bosque

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Rapid assessment of Opisthorchis viverrini IgG antibody in serum: A potential diagnostic biomarker to predict risk of cholangiocarcinoma in regions endemic for opisthorchiasis., Rutchanee Rodpai, Vor Luvira, Lakkhana Sadaow, Wattana Sukeepaisarnjaroen, Amnat Kitkhuandee, Krisada Paonariang, Oranuch Sanpool, Wannaporn Ittiprasert, Victoria H. Mann, Pewpan M Intapan, Paul J. Brindley, and Wanchai Maleewong

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An Innovative Test for the Rapid Detection of Specific IgG Antibodies in Human Whole-Blood for the Diagnosis of Infection, Lakkhana Sadaow, Rutchanee Rodpai, Penchom Janwan, Patcharaporn Boonroumkaew, Oranuch Sanpool, Tongjit Thanchomnang, Hiroshi Yamasaki, Wannaporn Ittiprasert, Victoria H. Mann, Paul J. Brindley, Wanchai Maleewong, and Pewpan M. Intapan

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Biorepository best practices for research and clinical investigations, Micheline Sanderson-November, Sylvia Silver, Vanessa Hooker, and Monika Schmelz