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Submissions from 2023

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Meeting report: transposable elements at the crossroads of evolution, health and disease 2023, Irina R. Arkhipova, Kathleen H. Burns, Katherine B. Chiappinelli, Edward B. Chuong, Clement Goubert, Alba Guarné, Amanda M. Larracuente, E Alice Lee, and Henry L. Levin

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Proceedings of the inaugural Dark Genome Symposium: November 2022, Jef D. Boeke, Kathleen H. Burns, Katherine B. Chiappinelli, Marie Classon, John M. Coffin, Daniel D. DeCarvalho, Joseph D. Dukes, Benjamin Greenbaum, George Kassiotis, Sarah K. Knutson, Arnold J. Levine, Avindra Nath, Sophie Papa, Daniel Rios, John Sedivy, and David T. Ting

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Neurogenetics and Epigenetics of Loneliness, Abdalla Bowirrat, Igor Elman, Catherine A. Dennen, Marjorie C. Gondré-Lewis, Jean Lud Cadet, Jag Khalsa, David Baron, Diwanshu Soni, Mark S. Gold, Thomas J. McLaughlin, Debasis Bagchi, Eric R. Braverman, Mauro Ceccanti, Panayotis K. Thanos, Edward Justin Modestino, Keerthy Sunder, Nicole Jafari, Foojan Zeine, Rajendra D. Badgaiyan, Debmalya Barh, Milan Makale, Kevin T. Murphy, and Kenneth Blum

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AP-1/c-Fos supports SIV and HIV-1 latency in CD4 T cells infected, Viviana Cobos Jiménez, Aviva Geretz, Andrey Tokarev, Philip K. Ehrenberg, Selase Deletsu, Kawthar Machmach, Prakriti Mudvari, J Natalie Howard, Amanda Zelkoski, Dominic Paquin-Proulx, Gregory Q. Del Prete, Caroline Subra, Eli A. Boritz, Alberto Bosque, Rasmi Thomas, and Diane L. Bolton

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A first-in-human germline-targeting HIV nanoparticle vaccine induced broad and publicly targeted helper T cell responses, Kristen W. Cohen, Stephen C. De Rosa, William J. Fulp, Allan C. deCamp, Andrew Fiore-Gartland, Celia R. Mahoney, Sarah Furth, Josh Donahue, Rachael E. Whaley, Lamar Ballweber-Fleming, Aaron Seese, Katharine Schwedhelm, Daniel Geraghty, Greg Finak, Sergey Menis, David J. Leggat, Farhad Rahaman, Angela Lombardo, Bhavesh R. Borate, Vincent Philiponis, Janine Maenza, David Diemert, Orpheus Kolokythas, Nadia Khati, Jeffrey Bethony, Ollivier Hyrien, Dagna S. Laufer, Richard A. Koup, Adrian B. McDermott, William R. Schief, and M Juliana McElrath

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The latency reversing agent HODHBt synergizes with IL-15 to enhance cytotoxic function of HIV-specific CD8+ T-cells, Dennis C. Copertino, Carissa S. Holmberg, Jared Weiler, Adam R. Ward, J Natalie Howard, Callie Levinger, Alina Ps Pang, Michael J. Corley, Friederike Dündar, Paul Zumbo, Doron Betel, Rajesh T. Gandhi, Deborah K. McMahon, Ronald J. Bosch, Noemi Linden, Bernard J. Macatangay, Joshua C. Cyktor, Joseph J. Eron, John W. Mellors, Colin Kovacs, Erica Benko, Alberto Bosque, and R Brad Jones

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The latency-reversing agent HODHBt synergizes with IL-15 to enhance cytotoxic function of HIV-specific T cells, Dennis C. Copertino, Carissa S. Holmberg, Jared Weiler, Adam R. Ward, J Natalie Howard, Callie Levinger, Alina Ps Pang, Michael J. Corley, Friederike Dündar, Paul Zumbo, Doron Betel, Rajesh T. Gandhi, Deborah K. McMahon, Ronald J. Bosch, Noemi Linden, Bernard J. Macatangay, Joshua C. Cyktor, Joseph J. Eron, John W. Mellors, Colin Kovacs, Erika Benko, Alberto Bosque, and R Brad Jones

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Transfusion-transmitted Babesia spp.: a changing landscape of epidemiology, regulation, and risk mitigation, Steven J. Drews, Anne M. Kjemtrup, Peter J. Krause, Grayson Lambert, David A. Leiby, Antoine Lewin, Sheila F. O'Brien, Christian Renaud, Laura Tonnetti, and Evan M. Bloch

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Transfusion-transmitted Babesia spp.: a changing landscape of epidemiology, regulation, and risk mitigation, Steven J. Drews, Anne M. Kjemtrup, Peter J. Krause, Grayson Lambert, David A. Leiby, Antoine Lewin, Sheila F. O'Brien, Christian Renaud, Laura Tonnetti, and Evan M. Bloch

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Severe autoimmune lymphoproliferative syndrome phenotype in a pediatric patient with a germline FAS gene variant, Alexandra Dreyzin, Jinjun Cheng, David Leitenberg, and Yaser Diab

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State of the science and future directions for research on HIV and cancer: Summary of a joint workshop sponsored by IARC and NCI, Eric A. Engels, Meredith S. Shiels, Ruanne V. Barnabas, Julia Bohlius, Paul Brennan, Jessica Castilho, Stephen J. Chanock, Megan A. Clarke, Anna E. Coghill, Jean-Damien Combes, Scott Dryden-Peterson, Gypsyamber D'Souza, Satish Gopal, Antoine Jaquet, Kathryn Lurain, Alain Makinson, Jeffrey Martin, Mazvita Muchengeti, Robert Newton, Fred Okuku, Jackson Orem, Joel M. Palefsky, Ramya Ramaswami, Hilary A. Robbins, Keith Sigel, Sylvia Silver, Gita Suneja, Robert Yarchoan, and Gary M. Clifford

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IL-15 and N-803 for HIV Cure Approaches, J Natalie Howard and Alberto Bosque

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Targeted insertion and reporter transgene activity at a gene safe harbor of the human blood fluke, Schistosoma mansoni, Wannaporn Ittiprasert, Max F. Moescheid, Cristian Chaparro, Victoria H. Mann, Thomas Quack, Rutchanee Rodpai, André Miller, Prapakorn Wisitpongpun, Watunyoo Buakaew, Margaret Mentink-Kane, Sarah Schmid, Anastas Popratiloff, Christoph G. Grevelding, Christoph Grunau, and Paul J. Brindley

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Oncogenic Transformation Drives DNA Methylation Loss and Transcriptional Activation of Transposable Element Loci, Tomas Kanholm, Uzma Rentia, Melissa Hadley, Jennifer A. Karlow, Olivia L. Cox, Noor Diab, Matthew L. Bendall, Tyson Dawson, James I. McDonald, Wenbing Xie, Keith A. Crandall, Kathleen H. Burns, Stephen B. Baylin, Hariharan Easwaran, and Katherine B. Chiappinelli

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Cocaine Use May Moderate the Associations of HIV and Female Sex with Neurocognitive Impairment in a Predominantly African American Population Disproportionately Impacted by HIV and Substance Use, Hong Lai, David D. Celentano, Glenn Treisman, Jag Khalsa, Gary Gerstenblith, Bryan Page, Raul N. Mandler, Yihong Yang, Betty Salmeron, Sandeepan Bhatia, Shaoguang Chen, Shenghan Lai, Karl Goodkin, and Man Charurat

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Comparative transcriptomics from intestinal cells of permissive and non-permissive hosts during infection reveals unique signatures of protection and host specificity, Andrea Langeland, Emilia Grill, Amol C. Shetty, Damien M. O'Halloran, and John M. Hawdon

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Comparative transcriptomics from intestinal cells of permissive and non-permissive hosts during infection reveals unique signatures of protection and host specificity, Andrea Langeland, Emilia Grill, Amol C. Shetty, Damien M. O'Halloran, and John M. Hawdon

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Immunity mediates host specificity in the human hookworm, Andrea Langeland, Elise L. McKean, Damien M. O'Halloran, and John M. Hawdon

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Development of screening assays for use of broadly neutralizing antibodies in people with HIV, Rebecca M. Lynch and Katharine J. Bar

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Development of screening assays for use of broadly neutralizing antibodies in people with HIV, Rebecca M. Lynch and Katharine J. Bar

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Inhibition of carbonic anhydrase using aspirin is a novel method to block schistosomiasis infection of the parasitic trematode, Schistosoma mansoni, in the intermediate snail host, Biomphalaria glabrata, Simone Parn, Gabriela Lewis, and Matty Knight

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Polio eradication efforts: Above all, do no harm, Stanley A. Plotkin and Konstantin Chumakov

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Bacterial contact induces polar plug disintegration to mediate whipworm egg hatching, Amicha Robertson, Joseph Sall, Mericien Venzon, Janet J. Olivas, Xuhui Zheng, Michael Cammer, Noelle Antao, Chunyi Zhou, Joseph C. Devlin, Rafaela Saes Thur, Jeffrey Bethony, Peter Nejsum, Bo Shopsin, Victor J. Torres, Feng-Xia Liang, and Ken Cadwell

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Tetraspanins from the liver fluke Opisthorchis viverrini stimulate cholangiocyte migration and inflammatory cytokine production, Apisit Ruangsuwast, Michael J. Smout, Paul J. Brindley, Alex Loukas, Thewarach Laha, and Sujittra Chaiyadet

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Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes, Rajeshwer S. Sankhala, Vincent Dussupt, Gina Donofrio, Gregory D. Gromowski, Rafael A. De La Barrera, Rafael A. Larocca, Letzibeth Mendez-Rivera, Anna Lee, Misook Choe, Weam Zaky, Grace Mantus, Jaime L. Jensen, Wei-Hung Chen, Neelakshi Gohain, Hongjun Bai, Michael K. McCracken, Rosemarie D. Mason, David Leggat, Bonnie M. Slike, Ursula Tran, Ningbo Jian, Peter Abbink, Rebecca Peterson, Eric Araujo Mendes, Rafael Freitas de Oliveira Franca, Guilherme Amaral Calvet, Ana Maria Bispo de Filippis, Adrian McDermott, Mario Roederer, Mayda Hernandez, Amie Albertus, and Edgar Davidson

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Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1, Marta Sanz, Ann Marie Weideman, Adam R. Ward, Matthew L. Clohosey, Susana Garcia-Recio, Sara R. Selitsky, Brendan T. Mann, Marie Anne Iannone, Chloe P. Whitworth, Alisha Chitrakar, Carolina Garrido, Jennifer Kirchherr, Alisha R. Coffey, Yi-Hsuan Tsai, Shahryar Samir, Yinyan Xu, Dennis Copertino, Alberto Bosque, Brad R. Jones, Joel S. Parker, Michael G. Hudgens, Nilu Goonetilleke, and Natalia Soriano-Sarabia

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Ultrasound-guided lymph node fine-needle aspiration for evaluating post-vaccination germinal center responses in humans, Larissa L. Scholte, David J. Leggat, Kristen W. Cohen, Lara Hoeweler, Guacyara C. Erwin, Farhard Rahaman, Angela Lombardo, Vincent Philiponis, Dagna S. Laufer, Heather Siefers, Alexis M. Ruppel, Joshua Brand, Janine Maenza, Rhi Bronson, Madhu Prabhakaran, Jalen Jean-Baptiste, Orpheus Kolokythas, Aimee A. Desrosiers, Caroline K. Thoreson, Antje Heit, Nadia J. Khati, Elissa Malkin, M Juliana McElrath, Adrian B. McDermott, William R. Schief, David Diemert, and Jeffrey M. Bethony

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Diagnosis and monitoring of virus-associated cancer using cell-free DNA, Larissa Ls Scholte, Jeffrey M. Bethony, and Rena R. Xian

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Diagnosis and monitoring of virus-associated cancer using cell-free DNA, Larissa Ls Scholte, Jeffrey M. Bethony, and Rena R. Xian

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The AIDS and Cancer Specimen Resource (ACSR): HIV malignancy specimens and data available at no cost, Sylvia Silver and Monika Schmelz

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Excretory/Secretory Proteome of Females and Males of the Hookworm, Samuel C. Uzoechi, Bruce A. Rosa, Kumar Sachin Singh, Young-Jun Choi, Bethany K. Bracken, Paul J. Brindley, R Reid Townsend, Robert Sprung, Bin Zhan, Maria-Elena Bottazzi, John M. Hawdon, Yide Wong, Alex Loukas, Sergej Djuranovic, and Makedonka Mitreva

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Protein Exaptation by Endogenous Retroviral Elements Shapes Tumor Cell Senescence and Downstream Immune Signaling, Reddick R. Walker and Katherine B. Chiappinelli

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Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility, Ruby White, Javier Sotillo, María Eugenia Ancarola, Anne Borup, Anders Toftegaard Boysen, Paul J. Brindley, Edit I. Buzás, Serena Cavallero, Sujittra Chaiyadet, Iain W. Chalmers, Marcela A. Cucher, Maude Dagenais, Chelsea N. Davis, Eileen Devaney, Maria A. Duque-Correa, Ramon Marc Eichenberger, Santiago Fontenla, Thomas A. Gasan, Cornelis H. Hokke, Maja Kosanovic, Marije E. Kuipers, Thewarach Laha, Alex Loukas, Rick M. Maizels, Antonio Marcilla, Hynek Mazanec, Russell M. Morphew, Kyriaki Neophytou, Linh Thuy Nguyen, Esther Nolte-'t Hoen, Michael Povelones, and Mark W. Robinson

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Anticipating HIV viral escape - resistance to active and passive immunization, Carolyn Williamson, Rebecca M. Lynch, and Penny L. Moore

Submissions from 2022

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HIV, psychological resilience, and substance misuse during the COVID-19 pandemic: A multi-cohort study, Marianna K. Baum, Javier A. Tamargo, Janet Diaz-Martinez, Ivan Delgado-Enciso, Christina S. Meade, Gregory D. Kirk, Shruti H. Mehta, Richard Moore, Michele D. Kipke, Steven J. Shoptaw, Brian Mustanski, Raul N. Mandler, Jag H. Khalsa, Suzanne Siminski, Marjan Javanbakht, and Pamina M. Gorbach

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Editorial: Lipids and Inflammation in Health and Disease, Evgeny Bezsonov, Vasily Sukhorukov, Michael Bukrinsky, and Alexander Orekhov

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Celebrating a year of clinical and translational research in Blood Advances, Catherine M. Bollard and Andrew Weyrich

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The Cultured T Model of HIV Latency, Alberto Bosque

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Silencing of Tetraspanin Gene Expression Results in Reduced Secretion of Extracellular Vesicles, Sujittra Chaiyadet, Javier Sotillo, Watchara Krueajampa, Sophita Thongsen, Michael Smout, Paul J. Brindley, Thewarach Laha, and Alex Loukas

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Silencing of Tetraspanin Gene Expression Results in Reduced Secretion of Extracellular Vesicles, Sujittra Chaiyadet, Javier Sotillo, Watchara Krueajampa, Sophita Thongsen, Michael Smout, Paul J. Brindley, Thewarach Laha, and Alex Loukas

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Knockout of liver fluke granulin, Ov-grn-1, impedes malignant transformation during chronic infection with Opisthorchis viverrini, Sujittra Chaiyadet, Sirikachorn Tangkawattana, Michael J. Smout, Wannaporn Ittiprasert, Victoria H. Mann, Raksawan Deenonpoe, Patpicha Arunsan, Alex Loukas, Paul J. Brindley, and Thewarach Laha

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IL-27 induces IFN/STAT1-dependent genes and enhances function of TIGIT HIVGag-specific T cells, Jie Cheng, Timothy G. Myers, Callie Levinger, Princy Kumar, Jai Kumar, Bruktawit A. Goshu, Alberto Bosque, and Marta Catalfamo

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Inhibiting DNA methylation improves antitumor immunity in ovarian cancer, Katherine B. Chiappinelli and Stephen B. Baylin

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Safety and immunogenicity of the Na-APR-1 hookworm vaccine in infection-naïve adults, David J. Diemert, Maria Zumer, Doreen Campbell, Shannon Grahek, Guangzhao Li, Jin Peng, Maria Elena Bottazzi, Peter Hotez, and Jeffrey Bethony

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Safety and immunogenicity of the Na-APR-1 hookworm vaccine in infection-naïve adults, David J. Diemert, Maria Zumer, Doreen Campbell, Shannon Grahek, Guangzhao Li, Jin Peng, Maria Elena Bottazzi, Peter Hotez, and Jeffrey Bethony

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Climate change and parasitic risk to the blood supply, Steven J. Drews, Silvano Wendel, David A. Leiby, Laura Tonnetti, Ines Ushiro-Lumb, Sheila F. O'Brien, Ryanne W. Lieshout-Krikke, and Evan M. Bloch

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Extracellular vesicles carrying HIV-1 Nef induce long-term hyperreactivity of myeloid cells, Larisa Dubrovsky, Beda Brichacek, N M. Prashant, Tatiana Pushkarsky, Nigora Mukhamedova, Andrew J. Fleetwood, Yangsong Xu, Dragana Dragoljevic, Michael Fitzgerald, Anelia Horvath, Andrew J. Murphy, Dmitri Sviridov, and Michael I. Bukrinsky

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Transposable element regulation and expression in cancer, Erin E. Grundy, Noor Diab, and Katherine B. Chiappinelli

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Cocaine use associated gut permeability and microbial translocation in people living with HIV in the Miami Adult Study on HIV (MASH) cohort, Jacqueline Hernandez, Javier A. Tamargo, Sabrina Sales Martinez, Haley R. Martin, Adriana Campa, Rafick-Pierre Sékaly, Rebeka Bordi, Kenneth E. Sherman, Susan D. Rouster, Heidi L. Meeds, Jag H. Khalsa, Raul N. Mandler, Shenghan Lai, and Marianna K. Baum

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Culturing and Genetically Manipulating Entomopathogenic Nematodes, Christa Heryanto, Ramesh Ratnappan, Damien M. O'Halloran, John M. Hawdon, and Ioannis Eleftherianos

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THE GENERATION AND APPLICATION OF ANTIGEN-SPECIFIC T CELL THERAPIES FOR CANCER AND VIRAL-ASSOCIATED DISEASE, Amy B. Hont, Allison B. Powell, Danielle K. Sohai, Izabella K. Valdez, Maja Stanojevic, Ashley E. Geiger, Kajal Chaudhary, Ehsan K. Dowlati, Catherine M. Bollard, and Conrad Russell Cruz

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Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production, Benjamin J. Hulme, Kathrin K. Geyer, Josephine E. Forde-Thomas, Gilda Padalino, Dylan W. Phillips, Wannaporn Ittiprasert, Shannon E. Karinshak, Victoria H. Mann, Iain W. Chalmers, Paul J. Brindley, Cornelis H. Hokke, and Karl F. Hoffmann

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RNA-Guided Cas12a- and Cas9-Catalyzed Knockout and Homology Directed Repair of the Omega-1 Locus of the Human Blood Fluke,, Wannaporn Ittiprasert, Chawalit Chatupheeraphat, Victoria H. Mann, Wenhui Li, André Miller, Taiwo Ogunbayo, Kenny Tran, Yousef N. Alrefaei, Margaret Mentink-Kane, and Paul J. Brindley

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Palatal morphology predicts the paleobiology of early salamanders, Jia Jia, Guangzhao Li, and Ke-Qin Gao

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Review: Cannabinoids as Medicinals, Jag H. Khalsa, Gregory Bunt, Kenneth Blum, Sanjay B. Maggirwar, Marc Galanter, and Marc N. Potenza

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Immune responses to Toxoplasma gondii, Imtiaz A. Khan and Magali Moretto

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Nfkbid-mediated humoral immunity during secondary toxoplasmosis, Imtiaz A. Khan and Magali Moretto

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Human immunodeficiency virus-1 Tat exerts its neurotoxic effects by downregulating Sonic hedgehog signaling, Irfan A. Khan, Arthur H. Worrad, Meera V. Singh, Sanjay B. Maggirwar, and Vir B. Singh

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Hit-and-Run Epigenetic Editing for Vectors of Snail-Borne Parasitic Diseases, Nelia Luviano, David Duval, Wannaporn Ittiprasert, Jean-Francois Allienne, Geneviève Tavernier, Cristian Chaparro, Celine Cosseau, and Christoph Grunau

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Short Communication: A Pilot Study of the Effects of Losartan Versus Placebo on Pneumoproteins in HIV: A Secondary Analysis of a Randomized Double Blind Study, David M. MacDonald, Gary Collins, Chris H. Wendt, Julian Wolfson, Russell P. Tracy, Frank Rhame, Steven Deeks, Stacey A. Rizza, Zelalem Temesgen, Caryn Morse, Angelike P. Liappis, Irini Sereti, Jason V. Baker, and Ken M. Kunisaki

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Infection of Endothelial Cells by Dengue Virus Induces ROS Production by Different Sources Affecting Virus Replication, Cellular Activation, Death and Vascular Permeability, Lana Monteiro Meuren, Elisa Beatriz Prestes, Michelle Premazzi Papa, Luiza Rachel de Carvalho, Yasmin Mucunã Mustafá, Leandro Silva da Costa, Andrea T. Da Poian, Marcelo Torres Bozza, and Luciana Barros Arruda

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The Persistence of HIV Diversity, Transcription, and Nef Protein in Kaposi's Sarcoma Tumors during Antiretroviral Therapy, David J. Nolan, Rebecca Rose, Rongzhen Zhang, Alan Leong, Gary B. Fogel, Larissa L. Scholte, Jeffrey M. Bethony, Paige Bracci, Susanna L. Lamers, and Michael S. McGrath

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Platelet-Released Factors: Their Role in Viral Disease and Applications for Extracellular Vesicle (EV) Therapy, Brita Ostermeier, Natalia Soriano-Sarabia, and Sanjay B. Maggirwar

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Executable models of immune signaling pathways in HIV-associated atherosclerosis, Mukta G. Palshikar, Rohith Palli, Alicia Tyrell, Sanjay Maggirwar, Giovanni Schifitto, Meera V. Singh, and Juilee Thakar

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Transgenesis in parasitic helminths: a brief history and prospects for the future, M J. Quinzo, M J. Perteguer, P J. Brindley, A Loukas, and J Sotillo

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Pharmacological Targeting of Sphingosine Kinases Impedes HIV-1 Infection of CD4 T Cells through SAMHD1 Modulation, Rachel S. Resop and Alberto Bosque

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Pharmacological Targeting of Sphingosine Kinases Impedes HIV-1 Infection of CD4 T Cells through SAMHD1 Modulation, Rachel S. Resop and Alberto Bosque

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Rapid assessment of Opisthorchis viverrini IgG antibody in serum: A potential diagnostic biomarker to predict risk of cholangiocarcinoma in regions endemic for opisthorchiasis., Rutchanee Rodpai, Vor Luvira, Lakkhana Sadaow, Wattana Sukeepaisarnjaroen, Amnat Kitkhuandee, Krisada Paonariang, Oranuch Sanpool, Wannaporn Ittiprasert, Victoria H. Mann, Pewpan M Intapan, Paul J. Brindley, and Wanchai Maleewong

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An Innovative Test for the Rapid Detection of Specific IgG Antibodies in Human Whole-Blood for the Diagnosis of Infection, Lakkhana Sadaow, Rutchanee Rodpai, Penchom Janwan, Patcharaporn Boonroumkaew, Oranuch Sanpool, Tongjit Thanchomnang, Hiroshi Yamasaki, Wannaporn Ittiprasert, Victoria H. Mann, Paul J. Brindley, Wanchai Maleewong, and Pewpan M. Intapan

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Biorepository best practices for research and clinical investigations, Micheline Sanderson-November, Sylvia Silver, Vanessa Hooker, and Monika Schmelz

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Defying convention in the time of COVID-19: Insights into the role of γδ T cells, Marta Sanz, Brendan T. Mann, Alisha Chitrakar, and Natalia Soriano-Sarabia

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Human Vδ2 T Cells and Their Versatility for Immunotherapeutic Approaches, Marta Sanz, Brendan T. Mann, Alisha Chitrakar, and Natalia Soriano-Sarabia

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Clostridia isolated from helminth-colonized humans promote the life cycle of Trichuris species, Shushan Sargsian, Ze Chen, Soo Ching Lee, Amicha Robertson, Rafaela Saes Thur, Julia Sproch, Joseph C. Devlin, Mian Zi Tee, Yi Xian Er, Richard Copin, Adriana Heguy, Alejandro Pironti, Victor J. Torres, Kelly V. Ruggles, Yvonne A. Lim, Jeffrey Bethony, P'ng Loke, and Ken Cadwell

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Validation of Biorepository Quality- Accreditation, Monika Schmelz and Sylvia Silver

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SARS CoV-2 mRNA vaccination exposes latent HIV to Nef-specific CD8 T-cells, Eva M. Stevenson, Sandra Terry, Dennis Copertino, Louise Leyre, Ali Danesh, Jared Weiler, Adam R. Ward, Pragya Khadka, Evan McNeil, Kevin Bernard, Itzayana G. Miller, Grant B. Ellsworth, Carrie D. Johnston, Eli J. Finkelsztein, Paul Zumbo, Doron Betel, Friederike Dündar, Maggie C. Duncan, Hope R. Lapointe, Sarah Speckmaier, Nadia Moran-Garcia, Michelle Premazzi Papa, Samuel Nicholes, Carissa J. Stover, Rebecca M. Lynch, Marina Caskey, Christian Gaebler, Tae-Wook Chun, Alberto Bosque, Timothy J. Wilkin, Guinevere Q. Lee, and Zabrina L. Brumme

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Chromosome-level genome of Schistosoma haematobium underpins genome-wide explorations of molecular variation., Andreas J Stroehlein, Pasi K Korhonen, V Vern Lee, Stuart A Ralph, Margaret Mentink-Kane, Hong You, Donald P McManus, Louis-Albert Tchuem Tchuenté, J Russell Stothard, Parwinder Kaur, Olga Dudchenko, Erez Lieberman Aiden, Bicheng Yang, Huanming Yang, Aidan M Emery, Bonnie L Webster, Paul J. Brindley, David Rollinson, Bill C H Chang, Robin B Gasser, and Neil D Young

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Trained Immunity and HIV Infection, Dmitri Sviridov, Yury I. Miller, and Michael I. Bukrinsky

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Cocaethylene, simultaneous alcohol and cocaine use, and liver fibrosis in people living with and without HIV, Javier A. Tamargo, Kenneth E. Sherman, Rafick-Pierre Sékaly, Rebeka Bordi, Daniela Schlatzer, Shenghan Lai, Jag H. Khalsa, Raul N. Mandler, Richard L. Ehman, and Marianna K. Baum

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Adherence of to gut epithelium and the tegument mediated via L-fucose binding adhesin, Prissadee Thanaphongdecha, Yaovalux Chamgramol, Chawalit Pairojkul, Raksawan Deenonpoe, Sutas Suttiprapa, Paul J. Brindley, and Banchob Sripa

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GENETIC SUBGROUPS INFORM ON PATHOBIOLOGY IN ADULT AND PEDIATRIC BURKITT LYMPHOMA, Nicole Thomas, Kostiantyn Dreval, Daniela S. Gerhard, Laura K. Hilton, Jeremy S. Abramson, Stefan K. Barta, Nancy L. Bartlett, Jeffrey Bethony, Kishor Bhatia, Jay Bowen, Anthony C. Bryan, Ethel Cesarman, Corey Casper, Manuela Cruz, Maureen Dyer, Pedro Farinha, Julie Gastier-Foster, Alina S. Gerrie, Bruno Grande, Timothy C. Greiner, Nicholas Griner, Thomas G. Gross, Nancy Lee Harris, John D. Irvin, Elaine S. Jaffe, David Henry, Rebecca Liddell Huppi, Fabio E. Leal, Michael Lee, Jean Paul Martin, Marie-Reine Martin, and Sam M. Mbulaiteye

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EBV+ lymphoproliferative diseases: opportunities for leveraging EBV as a therapeutic target, Keri Toner and Catherine M. Bollard

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No evidence that circulating HIV-specific immune responses contribute to persistent inflammation and immune activation in persons on long-term ART, Adam R. Ward, Allison S. Thomas, Eva M. Stevenson, Szu-Han Huang, Sheila M. Keating, Rajesh T. Gandhi, Deborah K. McMahon, Ronald J. Bosch, Bernard J. Macatangay, Joshua C. Cyktor, Joseph J. Eron, John W. Mellors, and R Brad Jones

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Probiotic therapy during vaccination alters antibody response to SHIV infection but not to commensals, Andrew Wilson, Jennifer Manuzak, Hua Liang, Ana R. Leda, Nichole R. Klatt, and Rebecca Lynch

Submissions from 2021

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Safety and immunogenicity of co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in Gabonese adults: a randomised, controlled, double-blind, phase 1 dose-escalation trial., Ayola A Adegnika, Sophia G de Vries, Frejus J Zinsou, Yabo J Honkepehedji, Jean-Claude Dejon Agobé, Kafui G Vodonou, Rodrigue Bikangui, Aurore Bouyoukou Hounkpatin, Emmanuel B Bache, Marguerite Massinga Loembe, Remko van Leeuwen, Marjan Molemans, Peter G Kremsner, Maria Yazdanbakhsh, Peter J Hotez, Maria Elena Bottazzi, Guangzhao Li, Jeffrey M. Bethony, David J. Diemert, and Martin P Grobusch

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Parasitic helminth infections in humans modulate Trefoil Factor levels in a manner dependent on the species of parasite and age of the host., Babatunde Adewale, Jonathan R Heintz, Christopher F Pastore, Heather L Rossi, Li-Yin Hung, Nurudeen Rahman, Jeff Bethony, David Diemert, James Ayorinde Babatunde, and De'Broski R Herbert

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Restriction Factor Expression in Vertically Infected Children Living With HIV-1., Martin Bortlik, Dennis C Copertino, Phillip M. Brailey, Greta A. Beckerle, Christopher E Ormsby, Michael G Rosenberg, Andrew A Wiznia, Rui André Saraiva Raposo, Douglas F. Nixon, and Miguel de Mulder Rougvie

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Chimeric antigen receptor-engineered natural killer cells: a promising cancer immunotherapy., Kajal Chaudhry, Ehsan Dowlati, and Catherine M. Bollard

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Secreted virulence factors from Heterorhabditis bacteriophora highlight its utility as a model parasite among Clade V nematodes., Eric Kenney, John M. Hawdon, Damien M. O'Halloran, and Ioannis Eleftherianos

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HIV-1 diversity considerations in the application of the Intact Proviral DNA Assay (IPDA)., Natalie N Kinloch, Yanqin Ren, Winiffer D Conce Alberto, Winnie Dong, Pragya Khadka, Szu Han Huang, Talia M Mota, Andrew Wilson, Aniqa Shahid, Don Kirkby, Marianne Harris, Colin Kovacs, Erika Benko, Mario A Ostrowski, Perla M Del Rio Estrada, Avery Wimpelberg, Christopher Cannon, W David Hardy, Lynsay MacLaren, Harris Goldstein, Chanson J Brumme, Guinevere Q Lee, Rebecca M. Lynch, Zabrina L Brumme, and R Brad Jones

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Comprehensive molecular profiling of UV-induced metastatic melanoma in Nme1/Nme2-deficient mice reveals novel markers of survival in human patients., M Kathryn Leonard, Gemma S Puts, Nidhi Pamidimukkala, Gautam Adhikary, Yili Xu, Eric Kwok, Yuxin Jin, Devin Snyder, Nicolette Matsangos, Marián Novak, Anup Mahurkar, Amol C Shetty, Radomir M Slominski, Edward C. De Fabo, Frances P. Noonan, Chi-Ping Day, Mohammed Rigi, Andrzej T Slominski, Michelle G Webb, David W Craig, Glenn Merlino, Richard L Eckert, John D Carpten, Zarko Manojlovic, and David M Kaetzel

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Monoclonal Antibodies Targeting an Opisthorchis viverrini Extracellular Vesicle Tetraspanin Protect Hamsters against Challenge Infection, Wuttipong Phumrattanaprapin, Mark Pearson, Darren Pickering, Bemnet Tedla, Michael Smout, Sujittra Chaiyadet, Paul J. Brindley, and Thewarach Laha

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Comparative assessment of immunochromatographic test kits using somatic antigens from adult Opisthorchis viverrini and IgG and IgG4 conjugates for serodiagnosis of human opisthorchiasis., Weeraya Phupiewkham, Lakkhana Sadaow, Oranuch Sanpool, Rutchanee Rodpai, Hiroshi Yamasaki, Wannaporn Ittiprasert, Victoria H. Mann, Paul J. Brindley, Wanchai Maleewong, and Pewpan M Intapan

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Editorial: Immunotherapies Towards HIV Cure., Maria Salgado, Alberto Bosque, and Carolina Garrido

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Urogenital Schistosomiasis-History, Pathogenesis, and Bladder Cancer., Lúcio Lara Santos, Júlio Santos, Maria João Gouveia, Carina Bernardo, Carlos Lopes, Gabriel Rinaldi, Paul J. Brindley, and José M Correia da Costa

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The Intact Non-Inducible Latent HIV-1 Reservoir is Established In an, Indra Sarabia, Szu-Han Huang, Adam R. Ward, R Brad Jones, and Alberto Bosque

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Locus-Specific Characterization of Human Endogenous Retrovirus Expression in Prostate, Breast, and Colon Cancers., Margaret C. Steiner, Jez L Marston, Luis P Iñiguez, Matthew L Bendall, Katherine B. Chiappinelli, Douglas F Nixon, and Keith A. Crandall

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Characterizing the Relationship Between Neutralization Sensitivity and, Andrew Wilson, Leyn Shakhtour, Adam Ward, Yanqin Ren, Melina Recarey, Eva Stevenson, Maria Korom, Colin Kovacs, Erika Benko, R Brad Jones, and Rebecca M. Lynch

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Characterizing the Relationship Between Neutralization Sensitivity and, Andrew Wilson, Leyn Shakhtour, Adam Ward, Yanqin Ren, Melina Recarey, Eva Stevenson, Maria Korom, Colin Kovacs, Erika Benko, R Brad Jones, and Rebecca M. Lynch

Submissions from 2020

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Liver fluke granulin promotes extracellular vesicle-mediated crosstalk and cellular microenvironment conducive to cholangiocarcinoma, Patpicha Arunsan, Apisit Chaidee, Christina J. Cochran, Victoria H. Mann, Toshihiko Tanno, Chutima Kumkhaek, Michael J. Smout, Shannon E. Karinshak, Rutchanee Rodpai, Javier Sotillo, Alex Loukas, Thewarach Laha, Paul J. Brindley, and Wannaporn Ittiprasert

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Liver fluke granulin promotes extracellular vesicle-mediated crosstalk and cellular microenvironment conducive to cholangiocarcinoma, Patpicha Arunsan, Apisit Chaidee, Christina J. Cochran, Victoria H. Mann, Toshihiko Tanno, Chutima Kumkhaek, Michael J. Smout, Shannon E. Karinshak, Rutchanee Rodpai, Javier Sotillo, Alex Loukas, Thewarach Laha, Paul J. Brindley, and Wannaporn Ittiprasert