Targeting the DHX9 RNA Helicase to Induce Antitumor Immunity in Small-Cell Lung Cancer

Authors

Katherine B. Chiappinelli, Department of Microbiology, Immunology, & Tropical Medicine, The George Washington University, Washington D.C.

Document Type

Journal Article

Publication Date

3-1-2024

Journal

Cancer discovery

Volume

14

Issue

3

DOI

10.1158/2159-8290.CD-23-1523

Abstract

Murayama and colleagues establish DHX9 as an exciting new target to induce viral mimicry and downstream antitumor immunity. The potential for use in combination with existing immune therapies is especially exciting in SCLC, an immunologically cold and deadly disease. See related article by Murayama et al., p. 468 (10) .

APA Citation

Chiappinelli, Katherine B., "Targeting the DHX9 RNA Helicase to Induce Antitumor Immunity in Small-Cell Lung Cancer" (2024). GW Authored Works. Paper 4590.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/4590

Department

Microbiology, Immunology, and Tropical Medicine