Biology of ovarian cancer: Models, microenvironment, and therapeutics: 15th Biennial Rivkin Center Ovarian Cancer Research Symposium

Authors

Katherine B. Chiappinelli, Department of Microbiology, Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA; The George Washington University Cancer Center, Washington, DC, USA. Electronic address: kchiapp1@gwu.edu.
Elizabeth L. Christie, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia. Electronic address: liz.christie@petermac.org.
Achuth Padmanabhan, Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, MD, USA; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA. Electronic address: achuth1@umbc.edu.

Document Type

Journal Article

Publication Date

9-1-2025

Journal

Gynecologic oncology

Volume

201

DOI

10.1016/j.ygyno.2025.08.014

Keywords

Model systems; Ovarian cancer; Treatment resistance; Tumor microenvironment

Abstract

The 15th Biennial Ovarian Cancer Research Symposium presented by the Rivkin Center for Ovarian Cancer and the American Association for Cancer Research held on September 20-21, 2024, in Seattle, WA covered cutting-edge research on the etiology and pathobiology of ovarian cancer. Several sessions focused on novel therapies including targeting the immunosuppressive microenvironment and advances in early detection. In this article we provide an overview of the key findings presented in the biology of ovarian cancer session, which covered novel model systems that accurately represent the disease, features of the tumor microenvironment (TME), and advances in understanding the genomic landscape and biomarkers of response.

APA Citation

Chiappinelli, Katherine B.; Christie, Elizabeth L.; and Padmanabhan, Achuth, "Biology of ovarian cancer: Models, microenvironment, and therapeutics: 15th Biennial Rivkin Center Ovarian Cancer Research Symposium" (2025). GW Authored Works. Paper 8021.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/8021

Department

Microbiology, Immunology, and Tropical Medicine