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Submissions from 2017

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dbVar structural variant cluster set for data analysis and variant comparison, Ben Busby, Lon Phan, Jeffrey Hsu, Le Quang Minh Tri, Micheala Willi, Tamer A. Mansour, Yan Kai, John R. Garner, and John R. Lopez

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Loss of the Transforming Growth Factor-β Effector β2-Spectrin Promotes Genomic Instability., Jian Chen, Vivek Shukla, Patrizia Farci, Jaclyn Andricovich, Wilma Jogunoori, Lawrence N Kwong, Lior H Katz, Kirti Shetty, Asif Rashid, Xiaoping Su, Jon White, Lei Li, Alan Yaoqi Wang, Boris Blechacz, Gottumukkala S Raju, Marta Davila, Bao-Ngoc Nguyen, John R Stroehlein, Junjie Chen, Sang Soo Kim, Heather Levin, Keigo Machida, Hidekazu Tsukamoto, Peter Michaely, Alexandros Tzatsos, Bibhuti Mishra, Richard Amdur, and Lopa Mishra

Fluorescent Proteins for Flow Cytometry., Teresa S Hawley, Robert G Hawley, and William G Telford

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MLL3/MLL4 are Required for CBP/p300 Binding on Enhancers and Super-enhancer Formation in Brown Adipogenesis., Binbin Lai, Ji-Eun Lee, Younghoon Jang, Lifeng Wang, Weiqun Peng, and Kai Ge

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Novel and functional ATG12 gene variants in sporadic Parkinson's disease., Yuequn Li, Jian Huang, Shuchao Pang, Haihua Wang, Aimei Zhang, Robert G Hawley, and Bo Yan

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Wbp2nl has a Developmental Role in Establishing Neural and Non-Neural Ectodermal Fates., Alexander Marchak, Paaqua A Grant, Karen M Neilson, Himani Datta Majumdar, Sergey Yaklichkin, Diana Johnson, and Sally A Moody

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Pa2G4 is a Novel Six1 Co-Factor That is Required for Neural Crest and Otic Development., Karen M Neilson, Genevieve Abbruzzesse, Kristy Kenyon, Vanessa Bartolo, Patrick Krohn, Dominique Alfandari, and Sally A Moody

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In Situ Microprobe Single-Cell Capillary Electrophoresis Mass Spectrometry: Metabolic Reorganization in Single Differentiating Cells in the Live Vertebrate (Xenopus laevis) Embryo., Rosemary M Onjiko, Erika P Portero, Sally A Moody, and Peter Nemes

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CNS Disease Diminishes The Therapeutic Functionality of Bone Marrow Mesenchymal Stem Cells., Alex Sargent, Lianhua Bai, Genevieve Shano, Molly Karl, Eric Garrison, Lahiru Ranasinghe, Sarah M Planchon, Jeffrey Cohen, and Robert H Miller

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Using Xenopus to Understand Human Disease and Developmental Disorders., Amy K Sater and Sally A Moody

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Corneal Epithelial Cells Function as Surrogate Schwann Cells for Their Sensory Nerves., Mary Ann Stepp, Gauri Tadvalkar, Raymond Hakh, and Sonali Pal-Ghosh

Helicobacter Pylori and Barrett's Esophagus: A Protective Factor or a Real Cause?, G Tomasello, F Giordano, M Mazzola, A Jurjus, P Damiani, S Nobile, F Carini, and A Leone

Helicobacter pylori and Barretts esophagus: a protective factor or a real cause?, G Tomasello, F Giordano, M Mazzola, R Jurjus, A Jurjus, P Damiani, S Nobile, F Carini, and A Leone

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Genetic Analysis of the ATG16L1 Gene Promoter in Sporadic Parkinson's Disease., Lixia Wang, Jian Huang, Shuchao Pang, Xianyun Qin, Ziyou Qi, Robert G Hawley, and Bo Yan

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A Meta-analysis of Anatomy Laboratory Pedagogies., Adam B Wilson, Corinne H Miller, Barbie A Klein, Melissa A Taylor, Michael Goodwin, Eve K Boyle, Kirsten Brown, Chantal Hoppe, and Michelle Lazarus

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Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia., Martha S Windrem, Mikhail Osipovitch, Zhengshan Liu, Janna Bates, Devin Chandler-Militello, Lisa Zou, Jared Munir, Steven Schanz, Katherine McCoy, Robert H Miller, Su Wang, Maiken Nedergaard, Robert L Findling, Paul J Tesar, and Steven A Goldman

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T-Cells Lacking HDAC11 Have Increased Effector Functions and Mediate Enhanced Alloreactivity In a Murine Model., David M Woods, Karrune V Woan, Fengdong Cheng, Andressa L Sodré, Dapeng Wang, Yongxia Wu, Zi Wang, Jie Chen, John Powers, Javier Pinilla-Ibarz, Yu Yu, Ya Zhang, Xuefeng Wu, Xiaoyan Zheng, Jeffrey Weber, Wayne Hancock, Edward Seto, Alejandro Villagra, Xue-Zhong Yu, and Eduardo M Sotomayor

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Discovery of 1,2,3-Triazole Derivatives for Multimodality PET/CT/Cryoimaging of Myelination in the Central Nervous System., Chunying Wu, Brendan Eck, Sheng Zhang, Junqing Zhu, Anand Dev Tiwari, Yifan Zhang, Robert Miller, and +several additional authors

Submissions from 2016

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Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis., Jaclyn Andricovich, Yan Kai, Weiqun Peng, Adlen Foudi, and Alexandros Tzatsos

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Lysine-Specific Histone Demethylases in Normal and Malignant Hematopoiesis., Jaclyn Andricovich, Yan Kai, and Alexandros Tzatsos

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Functional Divergence of the Nuclear Receptor NR2C1 as a Modulator of Pluripotentiality During Hominid Evolution., Jennifer L Baker, Katherine A Dunn, Joseph Mingrone, Bernard A Wood, Beverly A Karpinski, Chet C Sherwood, Derek E Wildman, Thomas M Maynard, and Joseph P Bielawski

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Testicular receptor 2, Nr2c1, is associated with stem cells in the developing olfactory epithelium and other cranial sensory and skeletal structures., Jennifer L. Baker, Bernard Wood, Beverly A. Karpinski, Anthony S. LaMantia, and Thomas M. Maynard

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Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm., Shailly Gaur, Max Mandelbaum, Mona B. Herold, Himani Majumdar, Karen M. Neilson, Thomas M. Maynard, Kathy Mood, Ira O. Daar, and Sally Ann Moody

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Nrf2: not "lost in translation"., Robert G. Hawley and Irene Riz

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Inflammatory bowel disease, colorectal cancer and type 2 diabetes mellitus: The links., Abdo Jurjus, Assad Eid, Sahar Al Kattar, Marie Noel Zeenny, Alice Gerges-Geagea, Rosalyn A. Jurjus, and +10 additional authors

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Curricular response to increase recall and transfer of anatomical knowledge into the obstetrics/gynecology clerkship., Rosalyn A. Jurjus, Kirsten Brown, Ellen Goldman, Artin Galoosian, Gisela Butera, and Jill M. Krapf

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When Family History Matters: The Importance of Lineage Analyses and Fate Maps for Explaining Animal Development., Steven L. Klein and Sally A. Moody

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High-sensitivity Mass Spectrometry for Probing Gene Translation in Single Embryonic Cells in the Early Frog (Xenopus) Embryo, Camille Lombard-Banek, Sally Ann Moody, and Peter Nemes

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Single-cell mass spectrometry for discovery proteomics: quantifying translational cell heterogeneity in the 16-cell frog (Xenopus) embryo, Camille Lombard-Banek, Sally Ann Moody, and Peter Nemes

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Label-free Quantification of Proteins in Single Embryonic Cells with Neural Fate in the Cleavage-Stage Frog (Xenopus laevis) Embryo using Capillary Electrophoresis Electrospray Ionization High-Resolution Mass Spectrometry (CE-ESI-HRMS)., Camille Lombard-Banek, Sushma Reddy, Sally A Moody, and Peter Nemes

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Label-free Quantification of Proteins in Single Embryonic Cells with Neural Fate in the Cleavage-Stage Frog (Xenopus laevis) Embryo using CE-ESI-HRMS, Camille Lombard-Banek, Sushma Reddy, Sally Ann Moody, and Peter Nemes

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The Activators of Cyclin-Dependent Kinase 5 p35 and p39 Are Essential for Oligodendrocyte Maturation, Process Formation, and Myelination., Fucheng Luo, Jessie Zhang, Kathryn Burke, Robert H. Miller, and Yan Yang

IBD, malignancy and oral microbiota: Analysis of the literature, M. Mazzola, F Carini, A Leone, P Damiani, M Messina, Abdo Jurjus, Alice Gerges Geagea, Rosalyn Jurjus, and G Tomasello

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Oligodendrocyte ablation as a tool to study demyelinating diseases, Ahdeah Pajoohesh-Ganji and Robert H. Miller

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K14+ compound niches are present on the mouse cornea early after birth and expand after debridement wounds., Ahdeah Pajoohesh-Ganji, Sonali Pal-Ghosh, Gauri Tadvalkar, and Mary Ann Stepp

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Topical Mitomycin-C enhances subbasal nerve regeneration and reduces erosion frequency in the debridement wounded mouse cornea., Sonali Pal-Ghosh, Ahdeah Pajoohesh-Ganji, Gauri Tadvalkar, Briana M Kyne, Xiaoqing Guo, James D Zieske, and Mary Ann Stepp

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Noncanonical SQSTM1/p62-Nrf2 pathway activation mediates proteasome inhibitor resistance in multiple myeloma cells via redox, metabolic and translational reprogramming., Irene Riz, Teresa S Hawley, Jeffrey W Marsal, and Robert G Hawley

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Design, Synthesis, and Evaluation of Fluorinated Radioligands for Myelin Imaging., Anand Dev Tiwari, Chunying Wu, Paul M Matthews, Robert H. Miller, and +7 more

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Contribution of the oligodendrocyte lineage to CNS repair and neurodegenerative pathologies., Reshmi Tognatta and Robert H. Miller

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Novel subcellular localization of the DNA helicase Twinkle at the kinetochore complex during mitosis in neuronal-like progenitor cells., Martine Uittenbogaard and Anne Chiaramello

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Localized JNK signaling regulates organ size during development., Helen Rankin Willsey, Xiaoyan Zheng, José Carlos Pastor-Pareja, A Jeremy Willsey, Philip A Beachy, and Tian Xu

Submissions from 2015

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Embryonic development of the right ventricular outflow tract and arrhythmias., Bastiaan J Boukens, Ruben Coronel, and Vincent M Christoffels

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Selective pressures in the human bony pelvis: Decoupling sexual dimorphism in the anterior and posterior spaces., Kirsten M. Brown

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Apoptosis of Oligodendrocytes during Early Development Delays Myelination and Impairs Subsequent Responses to Demyelination., Andrew V Caprariello, Courtney E Batt, Ingrid Zippe, Rita R Romito-DiGiacomo, Molly Karl, and Robert H. Miller

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Medical Students in Microscopic Anatomy and Pathology Laboratories: Design of an E-Learning Histology and Histopathology Atlas as an Evolving Response to Interdisciplinary Pre-Clinical Curricular Needs, Michelle S. Davis, Alexandra Mills, Gisela Butera, Donald S. Karcher, Patricia S. Latham, Janette Krum, and Rosalyn A. Jurjus

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The Use of Stem Cells in Burn Wound Healing: A Review, Fadi Ghieh, Rosalyn A. Jurjus, Amir Ibrahim, Alice Gerges Geagea, Hisham Daouk, Bassel El Baba, Sana Cham, Michel Matar, Wadih Zein, and Abdo Jurjus

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Weak tradeoff between xylem safety and xylem-specific hydraulic efficiency across the world's woody plant species., Sean M Gleason, Mark Westoby, Steven Jansen, Brendan Choat, Uwe G Hacke, Robert B Pratt, Radika Bhaskar, Tim J Brodribb, Sandra J Bucci, Kun-Fang Cao, Hervé Cochard, Sylvain Delzon, Jean-Christophe Domec, Ze-Xin Fan, Taylor S Feild, Anna L Jacobsen, Daniel M Johnson, Frederic Lens, Hafiz Maherali, Jordi Martínez-Vilalta, Stefan Mayr, Katherine A McCulloh, Maurizio Mencuccini, Patrick J Mitchell, Hugh Morris, Andrea Nardini, Jarmila Pittermann, Lenka Plavcová, Stefan G Schreiber, John S Sperry, Ian J Wright, and Amy E Zanne

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Atrial Fibrillation: Biophysics, Molecular Mechanisms, and Novel Therapies., Alexey V. Glukhov, Leonid V. Rosenshtraukh, Anamika Bhargava, Michele Miragoli, and Bas J. D. Boukens

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Regulation of Hedgehog signaling by ubiquitination., Elaine Y C Hsia, Yirui Gui, and Xiaoyan Zheng

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Assessment and feedback: essentials for an effective online learning of histology, Inaya Hussein, Rosalyn A. Jurjus, Aldo Gerbino, Abdo Jurjus, and Angelo Leone

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Once Upon a Microscopic Slide: The Story of Histology, Inaya Hussein, Mohamad Raad, Rawan Safa, Rosalyn A. Jurjus, and Abdo Jurjus

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Curricular response to increase recall and transfer of anatomical knowledge into the obstetrics/gynecology clerkship., Rosalyn A Jurjus, Kirsten Brown, Ellen Goldman, Artin Galoosian, Gisela Butera, and Jill M Krapf

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Curricular response to increase recall and transfer of anatomical knowledge into the obstetrics/gynecology clerkship., Rosalyn A. Jurjus, Kirsten Brown, Ellen Goldman, Artin Galoosian, Gisela Butera, and Jill M. Krapf

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The role of ciliary trafficking in Hedgehog receptor signaling., Jynho Kim, Elaine Y. C. Hsia, Amira Brigui, Anne Plessis, Philip A. Beachy, and Xiaoyan Zheng

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Recommendations for the Use of Inhaled Nitric Oxide Therapy in Premature Newborns with Severe Pulmonary Hypertension., John P Kinsella, Robin H Steinhorn, Usha S Krishnan, Jeffrey A Feinstein, Ian Adatia, David L. Wessel, and +12 additional authors

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Early neural ectodermal genes are activated by Siamois and Twin during blastula stages., Steven L. Klein and Sally Ann Moody

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Hard to swallow: Developmental biological insights into pediatric dysphagia., Anthony-Samuel LaMantia, Sally A Moody, Thomas M Maynard, Beverly A Karpinski, Irene E Zohn, David Mendelowitz, Norman H Lee, and Anastas Popratiloff

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Using Xenopus to discover new genes involved in branchiootorenal spectrum disorders., Sally A Moody, Karen M Neilson, Kristy L Kenyon, Dominique Alfandari, and Francesca Pignoni

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Transcriptional regulation of cranial sensory placode development, Sally Ann Moody and Anthony-Samuel LaMantia

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Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo., Fadi J Najm, Mayur Madhavan, Anita Zaremba, Elizabeth Shick, Robert T Karl, Robert H. Miller, and +17 additional authors

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Single-cell mass spectrometry reveals small molecules that affect cell fates in the 16-cell embryo., Rosemary M. Onjiko, Sally A. Moody, and Peter Nemes

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Partial denervation of sub-basal axons persists following debridement wounds to the mouse cornea., Ahdeah Pajoohesh-Ganji, Sonali Pal-Ghosh, Gauri Tadvalkar, Briana M. Kyne, Daniel R. Saban, and Mary Ann Stepp

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Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis, Panagiotis Papageorgis, Sait Ozturk, Arthur W. Lambert, Christiana M. Neophytou, Alexandros Tzatsos, Chen K. Wong, Sam Thiagalingam, and Andreas I. Constantinou

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KLF4-SQSTM1/p62-associated prosurvival autophagy contributes to carfilzomib resistance in multiple myeloma models., Irene Riz, Teresa S. Hawley, and Robert G. Hawley

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Syndecan-1 and Its Expanding List of Contacts, Mary Ann Stepp, Sonali Pal-Ghosh, Gauri Tadvalkar, and Ahdeah Pajoohesh-Ganji

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Dysmicrobism, inflammatory bowel disease and thyroiditis: Analysis of the literature, G Tomasello, P Tralongo, F Amoroso, P Damiani, E Sinagra, Rosalyn Jurjus Zein, and et al.

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The Vestibular System, P. P. Vidal, K. Cullen, L. S. Curthoys, S. Du Lac, G. Holstein, E. Idoux, A. Lysakowski, Kenna D. Peusner, A. Sans, and P. Smith

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Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic., Sharon W Way, Joseph R Podojil, Benjamin L Clayton, Anita Zaremba, Tassie L Collins, Rejani B Kunjamma, Andrew P Robinson, Pedro Brugarolas, Robert H. Miller, Stephen D Miller, and Brian Popko

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Microarray identification of novel genes downstream of Six1, a critical factor in cranial placode, somite, and kidney development., Bo Yan, Karen M. Neilson, Ramya Ranganathan, Thomas Maynard, Andrea Streit, and Sally Ann Moody

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CNS Myelin Wrapping Is Driven by Actin Disassembly., J. Bradley Zuchero, Meng-Meng Fu, Steven A. Sloan, Adiljan Ibrahim, Robert H. Miller, and et al.

Submissions from 2014

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Clinical and molecular genetics of the phosphodiesterases (PDEs)., Monalisa F Azevedo, Fabio R Faucz, Eirini Bimpaki, Anelia Horvath, Isaac Levy, Rodrigo B de Alexandre, Faiyaz Ahmad, Vincent Manganiello, and Constantine A Stratakis

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Novel animal pole-enriched maternal mRNAs are preferentially expressed in neural ectoderm, Paaqua A. Grant, Bo Yan, Michael A. Johnson, Diana L.E. Johnson, and Sally Ann Moody

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Estrogens control inflammation in experimental colitis, I. Hajj Hussen, A. Eid, R. Maksoud, S. Jambart, T. Bou Assi, Rosalyn A. Jurjus, and +11 additional authors

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Human t-lymphotrophic virus type 1 infected cells secrete exosomes that contain tax protein, Elizabeth Jaworski, Aarthi Narayanan, Rachel Van Duyne, Shabana Shabeer-Meyering, Sergey N. Iordanskiy, Mohammed Saifuddin, Ravi Das, Philippe V. Afonso, Gavin C. Sampey, Myung Chung, Anastas Popratiloff, Bindesh Shrestha, Mohit Sehgal, Pooja Jain, Akos Vertes, Renaud Mahieux, and Fatah Kashanchi

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Can anatomists teach living anatomy using ultrasound as a teaching tool?, Rosalyn A. Jurjus, Kathryn Dimorier, Kirsten Marie Brown, Frank Slaby, Hamid A. Shokoohi, Keith S. Boniface, and Yiju Teresa Liu

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Anatomical knowledge retention in third-year medical students prior to obstetrics and gynecology and surgery rotations, Rosalyn A. Jurjus, Juliet Lee, Samantha Ahle, Kirsten Marie Brown, Gisela Butera, Ellen F. Goldman, and Jill A. Krapf

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Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge/22q11 Deletion Syndrome, Beverly A. Karpinski, Thomas M. Maynard, Matthew S. Fralish, Samar Nuwayhid, Irene Zohn, Sally Ann Moody, and Anthony-Samuel LaMantia

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Simultaneous measurement of smoothened entry into and exit from the primary cilium, Jynho Kim, Elaine Y.C. Hsia, James Kim, Navdar Sever, Philip A. Beachy, and Xiaoyan Zheng

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Neural Transcription Factors: from Embryos to Neural Stem Cells, Hyun-Kyung Lee, Hyun-Shik Lee, and Sally Ann Moody

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Novel and functional ABCB1 gene variant in sporadic Parkinson's disease, Yuequn Li, Yonghua Li, Shuchao Pang, Wenhui Huang, Aimei Zhang, Robert G. Hawley, and Bo Yan

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A central role for vimentin in regulating repair function during healing of the lens epithelium, A. S. Menko, B. M. Bleaken, A. A. Libowitz, L. Zhang, Mary Ann Stepp, and J. L. Walker

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Inhibition of amyloid precursor protein secretases reduces recovery after spinal cord injury, Ahdeah Pajoohesh-Ganji, Mark P. Burns, Sonali Pal-Ghosh, Gauri Tadvalkar, Nicole G. Hokenbury, and Mary Ann Stepp

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Cytokine deposition alters leukocyte morphology and initial recruitment of monocytes and γδT-cells after corneal injury, Sonali Pal-Ghosh, Ahdeah Pajoohesh-Ganji, A. Sue Menko, Hye-Young Oh, Gauri Tadvalkar, Daniel R. Saban, and Mary Ann Stepp

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Establishing the pre-placodal region and breaking it into placodes with distinct identities, Jean P. Saint-Jeannet and Sally Ann Moody

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Subcellular metabolite and lipid analysis of Xenopus laevis eggs by LAESI mass spectrometry, Bindesh Shrestha, Prabhakar Sripadi, Brent R. Reschke, Holly D. Henderson, Matthew J. Powell, Sally Ann Moody, and Akos Vertes

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Wounding the cornea to learn how it heals, Mary Ann Stepp, James D. Zieske, Vickery Trinkaus-Randall, Briana Kyne, Sonali Pal-Ghosh, Gauri Tadvalkar, and Ahdeah Pajoohesh-Ganji

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Mitochondrial biogenesis: A therapeutic target for neurodevelopmental disorders and neurodegenerative diseases, Martine Uittenbogaard and Anne Chiaramello

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In situ metabolic analysis of single plant cells by capillary microsampling and electrospray ionization mass spectrometry with ion mobility separation., Linwen Zhang, Daniel P. Foreman, Paaqua A. Grant, Bindesh Shrestha, Sally A. Moody, Florent Villiers, June M. Kwak, and Akos Vertes

Submissions from 2013

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Three-dimensional shape differences in the bony pelvis of women with pelvic floor disorders, Kirsten Marie Brown, Victoria L. Handa, Katarzyna J. Macura, and Valerie B. DeLeon

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A novel and functional variant within the ATG5 gene promoter in sporadic Parkinson's disease, Dongfeng Chen, Cuiping Zhu, Xuenan Wang, Xungang Feng, Shuchao Pang, Wenhui Huang, Robert G. Hawley, and Bo Yan

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Blastomere explants to test for cell fate commitment during embryonic development, Paaqua A. Grant, Mona B. Herold, and Sally Ann Moody

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Modulation of β2 and β3 integrins in experimental colitis Induced by iodoacetamide and enteropathogenic E. coli, I. Abdallah Hajj Hussein, Rosalyn A. Jurjus, J. Saliba, S. Ghanem, R. Diab, T. Bou Assi, H. Daouk, A. Leone, and Abdo Jurjus

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Identification of an ABCB1 (P-glycoprotein)-positive carfilzomib-resistant myeloma subpopulation by the pluripotent stem cell fluorescent dye CDy1, Teresa S. Hawley, Irene Riz, Wenjing Yang, Yoshiyuki Wakabayashi, Louis Depalma, Young-Tae Chang, Weiqun Peng, Jun Zhu, and Robert G. Hawley

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Design for learning: Adapting the microscopic anatomy laboratory to adult learners, Rosalyn A. Jurjus, Janette Krum, and Ellen F. Goldman

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Cold atmospheric plasma in cancer therapy, Michael Keidar, Alex Shashurin, Olga Volotskova, Mary Ann Stepp, Priya Srinivasan, Anthony D. Sandler, and Barry Trink

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Conserved structural domains in FoxD4L1, a neural forkhead box transcription factor, are required to repress or activate target genes, Steven L. Klein, Karen M. Neilson, John Orban, Sergey Yaklichkin, Jennifer Hoffbauer, Kathy Mood, Ira O. Daar, and Sally Ann Moody

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On becoming neural: what the embryo can tell us about differentiating neural stem cells., Sally A. Moody, Steven L. Klein, Beverley A. Karpinski, Thomas M. Maynard, and Anthony-Samuel Lamantia

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How to Diagnose Like a Doctor on Your First Day in Medical School, Frank J. Slaby

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Identification of a novel 21bp-insertion variant within the LC3B gene promoter in sporadic Parkinson's disease, Jing Xu, Yan Yang, Shuchao Pang, Wenhui Huang, Xianyun Qin, Robert G. Hawley, and Bo Yan

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The DN2 myeloid-t (DN2mt) progenitor is a target cell for leukemic transformation by the TLX1 oncogene, Lynnsey A. Zweier-Renn, Irene Riz, Teresa S. Hawley, and Robert G. Hawley