Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
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Adema, C., Hillier, L., Jones, C., Loker, E., Knight, M., Minx, P., & +several additional authors (2017). Whole Genome Analysis of a Schistosomiasis-Transmitting Freshwater Snail.. Nature Communications, 8 (). http://dx.doi.org/10.1038/ncomms15451
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Reproduced with permission of Macmillan Publishers Ltd. Nature Communications