Document Type
Journal Article
Publication Date
5-16-2017
Journal
Nature Communications
Volume
8
DOI
10.1038/ncomms15451
Abstract
Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
APA Citation
Adema, C., Hillier, L., Jones, C., Loker, E., Knight, M., Minx, P., & +several additional authors (2017). Whole Genome Analysis of a Schistosomiasis-Transmitting Freshwater Snail.. Nature Communications, 8 (). http://dx.doi.org/10.1038/ncomms15451
Peer Reviewed
1
Open Access
1
Included in
Medical Immunology Commons, Medical Microbiology Commons, Parasitic Diseases Commons, Parasitology Commons, Tropical Medicine Commons
Comments
Reproduced with permission of Macmillan Publishers Ltd. Nature Communications