Intrinsic TGF-β signaling promotes age-dependent CD8+ T cell polyfunctionality attrition.

Authors

Rajarshi Bhadra, George Washington University
Magali M. Moretto, George Washington University
Julio C Castillo
Constantinos Petrovas
Sara Ferrando-Martinez
Upasana Shokal
Manuel Leal
Richard A Koup
Ioannis Eleftherianos
Imtiaz A. Khan, George Washington University

Document Type

Journal Article

Publication Date

6-1-2014

Journal

Journal of Clinical Investigation

Volume

124

Issue

6

Inclusive Pages

2441-2455

DOI

10.1172/JCI70522

Keywords

Aging--immunology; CD8-Positive T-Lymphocytes--immunology; Transforming Growth Factor beta1--immunology

Comments

This is an open access PubMed Central article. Click on link for full-text access.

APA Citation

Bhadra, R., Moretto, M. M., Castillo, J., Petrovas, C., Ferrando-Martinez, S., Shokal, U., Leal, M., Koup, R., Eleftherianos, I., & Khan, I. A. (2014). Intrinsic TGF-β signaling promotes age-dependent CD8+ T cell polyfunctionality attrition.. Journal of Clinical Investigation, 124 (6). http://dx.doi.org/10.1172/JCI70522

Peer Reviewed

1

Open Access

1