Title

Stevioside inhibits experimental fibrosis by down-regulating profibrotic Smad pathways and blocking hepatic stellate cell activation.

Document Type

Journal Article

Publication Date

6-1-2019

Journal

Basic & Clinical Pharmacology & Toxicology

Volume

124

Issue

6

Inclusive Pages

670-680

DOI

10.1111/bcpt.13194

Keywords

Actins; Animals; Cell Line; Collagen Type I; Collagenases; Deoxycytosine Nucleotides; Diterpenes, Kaurane; Down-Regulation; Fibrosis; Glucosides; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Lymphokines; MAP Kinase Signaling System; Male; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-myc; Rats; Rats, Wistar; Signal Transduction; Smad Proteins; Thioacetamide; Transforming Growth Factor beta1; Up-Regulation

Comments

Epub 2019 Jan 10

Peer Reviewed

1

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