Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models.

Authors

Sida Shen
Melissa Hadley, George Washington University
Kseniya Ustinova
Jiri Pavlicek
Tessa Knox, George Washington University
Satish Noonepalle, George Washington University
Mauricio T. Tavares
Chad A. Zimprich
Guiping Zhang
Matthew B. Robers
Cyril Bařinka
Alan P. Kozikowski
Alejandro Villagra, George Washington University

Document Type

Journal Article

Publication Date

9-26-2019

Journal

Journal of Medicinal Chemistry

Volume

62

Issue

18

Inclusive Pages

8557-8577

DOI

10.1021/acs.jmedchem.9b00946

Comments

Epub 2019 Sep 4

APA Citation

Shen, S., Hadley, M., Ustinova, K., Pavlicek, J., Knox, T., Noonepalle, S., Tavares, M. T., Zimprich, C. A., Zhang, G., Robers, M. B., Bařinka, C., Kozikowski, A. P., & Villagra, A. (2019). Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models.. Journal of Medicinal Chemistry, 62 (18). http://dx.doi.org/10.1021/acs.jmedchem.9b00946

Peer Reviewed

1