Healthy Drinks, Healthy Teeth - Ciunerkaq Tanqigtuq (The Future is Bright): A study protocol for a community-based, non-randomized sociobehavioral trial to reduce added sugar intake in Alaska Native Yup'ik children in the Yukon-Kuskokwim Delta

Authors

• Donald L. Chi, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA; Department of Health Systems and Population Health, University of Washington School of Public Health, 3980 15th Ave NE, Fourth Floor, Box 351621, Seattle, WA 98195, USA. Electronic address: dchi@uw.edu.
• Frances Marcus Lewis, Department of Child, Family and Population Health Nursing, University of Washington School of Nursing, Health Sciences Building, Room T-301, 1959 NE Pacific Street, Seattle, WA, 98195, USA.
• Philip Weinstein, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Lloyd Mancl, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Peter Milgrom, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Todd Edwards, Department of Health Systems and Population Health, University of Washington School of Public Health, 3980 15th Ave NE, Fourth Floor, Box 351621, Seattle, WA 98195, USA.
• Susan Coldwell, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Diane O'Brien, Center for Alaska Native Health Research, Institute of Arctic Biology, University of Alaska Fairbanks, 2141 Koyukuk Dr, Fairbanks, AK 99775, USA.
• Andrea Bersamin, Center for Alaska Native Health Research, Institute of Arctic Biology, University of Alaska Fairbanks, 2141 Koyukuk Dr, Fairbanks, AK 99775, USA.
• Scarlett Hopkins, Department of Obstetrics and Gynecology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
• Eliza Orr, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Patricia Rivera, Center for Alaska Native Health Research, Institute of Arctic Biology, University of Alaska Fairbanks, 2141 Koyukuk Dr, Fairbanks, AK 99775, USA.
• Dane Lenaker, Southeast Alaska Regional Health Consortium, Department of Dentistry, 3245 Hospital Drive, Juneau, AK 99801, USA.
• Allison Sylvetsky, Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, The George Washington University, 950 New Hampshire Ave NW, Washington, DC 20052,USA.
• Joel Gittelsohn, Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA.
• Peter Walter, Clinical Mass Spectrometry Core, NIH/NIDDK, Building 10-9C106, 10 Center Drive, MSC-1805, Bethesda, MD 20892, USA.
• Cameron L. Randall, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Deanna Wiseman, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Andrea Dock, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Alice Ko, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Joshua Orack, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Deeksha Nemawarkar, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Shraddha Panchal, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Jane Soper, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Courtney M. Hill, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Darragh Kerr, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Daisy Patiño Nguyen, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Chien-Yu Chen, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
• Ellen MacLachlan, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.

Document Type

Journal Article

Publication Date

12-1-2024

Journal

Contemporary clinical trials

Volume

147

DOI

10.1016/j.cct.2024.107734

Keywords

Added sugar; Artificial sweeteners; Health inequities; Indigenous populations; Oral health behaviors; Oral health disparities; Sugar-sweetened beverages

Abstract

BACKGROUND: This study protocol describes a community-based intervention that will seek to reduce added sugar intake in Yup'ik Alaska Native children by targeting reductions in sugar-sweetened fruit drinks. METHODS: A two-group non-randomized design will be used to evaluate the intervention in three Yup'ik communities in Alaska focusing on children age 1 to less than age 12 years with a minimum enrollment target of 192 children. Families in the intervention arm will participate in a program consisting of five sessions plus four brief check-ins, all delivered by a Yup'ik Community Health Worker. Modifications to the local store environment will be made to give families a place to purchase sugar-free water enhancers. Families in the delayed treatment control arm will receive no intervention during the main study period. There will be five data collection visits (baseline, 1-month, 3-months, 6-months, and 12-months) that will include collection of survey and dietary data, and a hair and plaque sample from each participating child. The outcomes will be change, from baseline to 6 months, in added sugar intake based on a validated hair biomarker (grams of added sugar/day). We hypothesize children in the intervention arm will have greater reductions in added sugar intake compared to children in the control arm as measured by the hair biomarker. DISCUSSION: This is one of the first known community-based sociobehavioral interventions aimed specifically at reducing added sugar intake in Alaska Native communities by targeting sugar-sweetened fruit drinks. TRIAL REGISTRATION: ClinicalTrials.govNCT05219448 (first posted on February 2, 2022).

APA Citation

Chi, Donald L.; Lewis, Frances Marcus; Weinstein, Philip; Mancl, Lloyd; Milgrom, Peter; Edwards, Todd; Coldwell, Susan; O'Brien, Diane; Bersamin, Andrea; Hopkins, Scarlett; Orr, Eliza; Rivera, Patricia; Lenaker, Dane; Sylvetsky, Allison; Gittelsohn, Joel; Walter, Peter; Randall, Cameron L.; Wiseman, Deanna; Dock, Andrea; Ko, Alice; Orack, Joshua; Nemawarkar, Deeksha; Panchal, Shraddha; Soper, Jane; Hill, Courtney M.; Kerr, Darragh; Nguyen, Daisy Patiño; Chen, Chien-Yu; and MacLachlan, Ellen, "Healthy Drinks, Healthy Teeth - Ciunerkaq Tanqigtuq (The Future is Bright): A study protocol for a community-based, non-randomized sociobehavioral trial to reduce added sugar intake in Alaska Native Yup'ik children in the Yukon-Kuskokwim Delta" (2024). GW Authored Works. Paper 6254.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/6254

Department

Exercise and Nutrition Sciences