Native Hawaiian and Pacific Islander populations in genomic research

Authors

Edra K. Ha, Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Daniel Shriner, Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Shawneequa L. Callier, Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Lorinda Riley, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Adebowale A. Adeyemo, Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Charles N. Rotimi, Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Amy R. Bentley, Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA. amy.bentley@nih.gov.

Document Type

Journal Article

Publication Date

9-30-2024

Journal

NPJ genomic medicine

Volume

9

Issue

1

DOI

10.1038/s41525-024-00428-6

Abstract

The role of genomic research and medicine in improving health continues to grow significantly, highlighting the need for increased equitable inclusion of diverse populations in genomics. Native Hawaiian and Pacific Islander (NHPI) communities are often missing from these efforts to ensure that the benefits of genomics are accessible to all individuals. In this article, we analyze the qualities of NHPI populations relevant to their inclusion in genomic research and investigate their current representation using data from the genome-wide association studies (GWAS) catalog. A discussion of the barriers NHPI experience regarding participating in research and recommendations to improve NHPI representation in genomic research are also included.

APA Citation

Ha, Edra K.; Shriner, Daniel; Callier, Shawneequa L.; Riley, Lorinda; Adeyemo, Adebowale A.; Rotimi, Charles N.; and Bentley, Amy R., "Native Hawaiian and Pacific Islander populations in genomic research" (2024). GW Authored Works. Paper 5569.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/5569

Department

Clinical Research and Leadership