Diagnostic Stewardship for Multiplex Respiratory Testing: What We Know and What Needs to Be Done

Authors

Jose Lucar, Division of Infectious Diseases, George Washington University School of Medicine and Health Sciences, 2150 Pennsylvania Avenue Northeast, Washington, DC 20037, USA.
Rebecca Yee, Department of Pathology, George Washington University School of Medicine and Health Sciences, 900 23rd Street Northwest, Washington, DC 20037, USA. Electronic address: ryee@mfa.gwu.edu.

Document Type

Journal Article

Publication Date

3-1-2024

Journal

Clinics in laboratory medicine

Volume

44

Issue

1

DOI

10.1016/j.cll.2023.10.001

Keywords

Antimicrobial resistance; Clinical utility; Diagnostic stewardship; Pneumonia; Respiratory infections; Syndromic panels

Abstract

Syndromic respiratory panels are now widely available in clinical microbiology laboratories and health care institutions. These panels can rapidly diagnose infections and detect antimicrobial resistance genes allowing for more rapid therapeutic optimization compared to standard microbiology approaches. However, given reimbursement concerns and limitations of multiplex molecular testing and results interpretation, maximum clinical utility and positive clinical outcomes depend on active diagnostic stewardship. Here, the authors review clinical outcomes of both upper and lower respiratory panels and present diagnostic stewardship strategies for optimal use of respiratory panels.

APA Citation

Jose Lucar and Rebecca Yee, "Diagnostic Stewardship for Multiplex Respiratory Testing: What We Know and What Needs to Be Done" (2024). GW Authored Works. Paper 4613.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/4613

Department

Pathology