Document Type

Journal Article

Publication Date



Journal of Aging Research

Inclusive Pages

Article ID 803864


We examined the relation between stress reactivity and 24 h glycemic control in 17 inactive, healthy older people (≥60 years) under both a novel psychophysical stress and a seated control condition. Plasma cortisol was measured over the course of the stress and recovery periods. Glycemic control was determined over the subsequent 3 h from an oral glucose tolerance test (OGTT) and over 24 h viacontinuous glucose monitoring (CGM). We observed significant (� < 0 . 0 5) elevations in perceived stress, cardiovascular activity, and peak cortisol response at 30 min (1 0 . 6 ± 3 . 1 versus 8 . 6 ± 2 . 6 μg·dL−1, resp.) during the stress compared with the control condition; however, 3 h OGTT glucose and insulin responses were similar between conditions. The CGM data suggested a 30–40 min postchallenge delay in peak glucose response and attenuated glucose clearance over the 6 h following the stress condition, but these alterations were not statistically significant. Healthy older people may demonstrate minimal disruption in metabolic resiliency following everyday psychological stress.


Reproduced with permission of Hindawi Publishing Corp. Journal of Aging Research.

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Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.

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Open Access