Document Type
Journal Article
Publication Date
2012
Journal
Journal of Aging Research
Inclusive Pages
Article ID 803864
Abstract
We examined the relation between stress reactivity and 24 h glycemic control in 17 inactive, healthy older people (≥60 years) under both a novel psychophysical stress and a seated control condition. Plasma cortisol was measured over the course of the stress and recovery periods. Glycemic control was determined over the subsequent 3 h from an oral glucose tolerance test (OGTT) and over 24 h viacontinuous glucose monitoring (CGM). We observed significant (� < 0 . 0 5) elevations in perceived stress, cardiovascular activity, and peak cortisol response at 30 min (1 0 . 6 ± 3 . 1 versus 8 . 6 ± 2 . 6 μg·dL−1, resp.) during the stress compared with the control condition; however, 3 h OGTT glucose and insulin responses were similar between conditions. The CGM data suggested a 30–40 min postchallenge delay in peak glucose response and attenuated glucose clearance over the 6 h following the stress condition, but these alterations were not statistically significant. Healthy older people may demonstrate minimal disruption in metabolic resiliency following everyday psychological stress.
Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.
APA Citation
DiPietro, L., Yeckel, C.W., Gribok, A. (2012). Response to acute psychophysical stress and 24-hour glycemic control in healthy older people. Journal of Aging Research:803864.
Peer Reviewed
1
Open Access
1
Comments
Reproduced with permission of Hindawi Publishing Corp. Journal of Aging Research.