Efficacy and safety of an extended nevirapine regimen in infant children of breastfeeding mothers with HIV-1 infection for prevention of postnatal HIV-1 transmission (HPTN 046): A randomised, double-blind, placebo-controlled trial

Authors

Hoosen M. Coovadia, University of the Witwatersrand, Johannesburg, South Africa
Elizabeth R. Brown, Fred Hutchinson Cancer Research Center, Seattle, WA
Mary Glenn Fowler, Johns Hopkins University
Tsungai Chipato, University of Zimbabwe, College of Medicine, Harare, Zimbabwe
Dhayendre Moodley, University of KwaZulu Natal, Durban, South Africa
Karim Manji, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
Philippa Musoke, Makerere University, Kampala, Uganda
Lynda Stranix-Chibanda, Johns Hopkins University
Vani Chetty, University of KwaZulu Natal, Durban, South Africa
Wafaie Fawzi, Harvard University
Clemensia Nakabiito, Makerere University, Kampala, Uganda
Lindiwe Msweli, University of KwaZulu Natal, Durban, South Africa
Roderick Kisenge, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
Laura Guay, George Washington University
Anthony Mwatha, Fred Hutchinson Cancer Research Center, Seattle, WA
Diana J. Lynn, Fred Hutchinson Cancer Research Center, Seattle, WA
Susan H. Eshleman, Johns Hopkins University
Paul Richardson, Johns Hopkins UniversityFollow
Kathleen George, Fred Hutchinson Cancer Research Center, Seattle, WA
Philip Andrew, Fred Hutchinson Cancer Research Center, Seattle, WA
Lynne M. Mofenson, National Institutes of Health, Rockville, MD
Sheryl Zwerski, National Institutes of Health, Rockville, MD
Yvonne Maldonado, Stanford University
HPTN 046 protocol team ,. + Additional Contributors

Document Type

Journal Article

Publication Date

1-21-2012

Journal

The Lancet

Volume

Volume 379, Issue 9812

Inclusive Pages

221-228

Keywords

Anti-HIV Agents--therapeutic use; Breast Feeding; HIV Infections--prevention & control; HIV-1; Infectious Disease Transmission; Vertical--prevention & control; Nevirapine--administration & dosage; Pregnancy Complications; Infectious--drug therapy

Comments

This is an open access PubMed Central article. Click on link for full-text access.

APA Citation

Coovadia, H. M., Brown, E. R., Fowler, M. G., Chipato, T., Moodley, D., Manji, K., Musoke, P., Stranix-Chibanda, L., Chetty, V., Fawzi, W., Nakabiito, C., Msweli, L., Kisenge, R., Guay, L., Mwatha, A., Lynn, D.J., Eshleman, S.H., Richardson, P., George, K., Andrew, P., Mofenson, L.M.l, Zwerski, S., Maldonado, Y. (2012). Efficacy and safety of an extended nevirapine regimen in infant children of breastfeeding mothers with HIV-1 infection for prevention of postnatal HIV-1 transmission (HPTN 046): A randomised, double-blind, placebo-controlled trial. The Lancet, 379(9812), 221-228.

Peer Reviewed

1

Open Access

1