Managing Renal Cell Carcinoma Associated Paraneoplastic Syndrome with Nephron-sparing Surgery in a Patient with von Hippel-Lindau.

Authors

John M DiBianco, George Washington UniversityFollow
Julie Y An
Sally Tanakchi
Zachary Stanik
Aidan McGowan
Mahir Maruf
Abhinav Sidana
Amit Lodha Jain
Akhil Muthigi
Arvin K George
Christopher Bayne, George Washington UniversityFollow
W Marston Linehan
Shawna L Boyle
Adam R Metwalli

Document Type

Journal Article

Publication Date

7-1-2017

Journal

Urology Case Reports

Volume

13

Inclusive Pages

101-103

DOI

10.1016/j.eucr.2017.02.015

Abstract

A patient with germline von Hippel-Lindau (VHL) gene alteration and history of multiple tumors present with classical paraneoplastic syndrome (PNS) associated with renal cell carcinoma (RCC). She underwent open nephron sparing surgery with resolution of symptoms. She remained without recurrence of RCC for the initial 2 years of her follow-up. To the best of our knowledge, this case represents the first in which PNS was specifically resolved using a partial nephrectomy in a patient with VHL. This case report provides initial evidence for the potential role of nephron sparing surgery in the management of paraneoplastic symptoms associated with hereditary RCC.

Comments

Reproduced with permission of Elsevier B.V. Urology Case Reports

Creative Commons License

This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

APA Citation

DiBianco, J., An, J., Tanakchi, S., Stanik, Z., McGowan, A., Maruf, M., Sidana, A., Jain, A., Muthigi, A., George, A., Bayne, C., Linehan, W., Boyle, S., & Metwalli, A. (2017). Managing Renal Cell Carcinoma Associated Paraneoplastic Syndrome with Nephron-sparing Surgery in a Patient with von Hippel-Lindau.. Urology Case Reports, 13 (). http://dx.doi.org/10.1016/j.eucr.2017.02.015

Peer Reviewed

1

Open Access

1