Controversies and challenges in research on urogenital schistosomiasis-associated bladder cancer
Trends in Parasitology
Bladder cancer; Schistosoma haematobium; Schistosomiasis haematobia; Urinary schistosomiasis; Urogenital schistosomiasis
Urogenital schistosomiasis, infection with Schistosoma haematobium, is linked to increased risk for the development of bladder cancer, but the importance of various mechanisms responsible for this association remains unclear, in part, owing to lack of sufficient and appropriate animal models. New advances in the study of this parasite, bladder regenerative processes, and human schistosomal bladder cancers may shed new light on the complex biological processes that connect S. haematobium infection to bladder carcinogenesis. © 2014 Elsevier Ltd.
Honeycutt, J., Hammam, O., Fu, C., & Hsieh, M. (2014). Controversies and challenges in research on urogenital schistosomiasis-associated bladder cancer. Trends in Parasitology, 30 (7). http://dx.doi.org/10.1016/j.pt.2014.05.004