Brain Stem Mechanisms Responsible for the Trigeminocardiac Reflex

Document Type

Journal Article

Publication Date

6-1-2015

Journal

Trigeminocardiac Reflex

DOI

10.1016/B978-0-12-800421-0.00006-0

Keywords

Acetylcholine; Autonomic; Heart rate; Nucleus ambiguus; Parasympathetic; Serotonin; Trigeminal; Vagal

Abstract

© 2015 Elsevier Inc. All rights reserved. This chapter summarizes recent work that characterizes the brain stem mechanisms responsible for the trigeminocardiac reflex (TCR). Among the topics discussed are the neurons involved in TCR circuitry, the transmitters released from these neurons, and the postsynaptic receptors activated in this reflex. Modulation of these reflex pathways by endogenously active neuromodulators, especially acetylcholine and serotonin, are explored. Finally, the chapter examines the possible role of the TCR in cardiorespiratory diseases, such as sudden infant death syndrome.

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