Document Type
Journal Article
Publication Date
2-1-2017
Journal
Cerebellum
Volume
16
Issue
1
Inclusive Pages
191-202
DOI
10.1007/s12311-016-0770-4
Abstract
Since the last review paper published in Cerebellum in 2002 [1], there has been a substantial increase in the number of experiments utilizing transgenic manipulations in murine cerebellar Purkinje cells. Most of these approaches were made possible with the use of the Cre/loxP methodology and pcp2/L7 based Cre recombinase expressing transgenic mouse strains. This review aims to summarize all studies which used Purkinje cell specific transgenesis since the first use of mouse strain with Purkinje cell specific Cre expression in 2002.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
APA Citation
Sługocka, A., Wiaderkiewicz, J., & Barski, J. (2017). Genetic Targeting in Cerebellar Purkinje Cells: an Update.. Cerebellum, 16 (1). http://dx.doi.org/10.1007/s12311-016-0770-4
Peer Reviewed
1
Open Access
1
Included in
Medical Pharmacology Commons, Medical Physiology Commons, Pharmacology Commons, Physiology Commons
Comments
Reproduced with permission of Springer international Publishing AG. Cerebellum