Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors.

Authors

Emmanuelle S Jecrois
Wang Zheng
Miriam Bornhorst, George Washington University
Yinghua Li
Daniel M Treisman
Daphine Muguyo
Sharon Huynh
Shayne F Andrew
Yuan Wang
Jingwen Jiang
Brianna R Pierce
Hongmei Mao
Matthew K Krause
Austin Friend
Francisco Nadal-Nicolas
Steven F. Stasheff, George Washington University
Wei Li, George Washington University
Hui Zong
Roger J. Packer, George Washington University
Yuan Zhu, George Washington University

Document Type

Journal Article

Publication Date

10-25-2021

Journal

Developmental Cell

Volume

56

Issue

20

Inclusive Pages

2871-2885.e6

DOI

10.1016/j.devcel.2021.08.004

Keywords

Animals; Brain Neoplasms; Disease Models, Animal; Eye; MAP Kinase Signaling System; Mice; Neurofibromatosis 1; Neuroglia; Optic Nerve; Optic Nerve Glioma; Stem Cells

Comments

Epub 2021 Aug 23

APA Citation

Jecrois, E., Zheng, W., Bornhorst, M., Li, Y., Treisman, D., Muguyo, D., Huynh, S., Andrew, S., Wang, Y., Jiang, J., Pierce, B., Mao, H., Krause, M., Friend, A., Nadal-Nicolas, F., Stasheff, S. F., Li, W., Zong, H., Packer, R. J., & Zhu, Y. (2021). Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors.. Developmental Cell, 56 (20). http://dx.doi.org/10.1016/j.devcel.2021.08.004

Peer Reviewed

1