PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma.
Document Type
Journal Article
Publication Date
8-22-2019
Journal
Nature Communications
Volume
10
Issue
1
DOI
10.1038/s41467-019-11732-6
Keywords
Animals; Antineoplastic Agents; Brain Stem Neoplasms; Cell Line, Tumor; Child; Cytokines; DNA Methylation; Diffuse Intrinsic Pontine Glioma; Epigenetic Repression; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Nicotinamide Phosphoribosyltransferase; Pons; Primary Cell Culture; Protein Phosphatase 2C; Synthetic Lethal Mutations; Xenograft Model Antitumor Assays
APA Citation
Fons, N. R., Sundaram, R. K., Breuer, G. A., Peng, S., McLean, R. L., Kalathil, A. N., Schmidt, M. S., Carvalho, D. M., Mackay, A., Jones, C., Carcaboso, Á. M., Nazarian, J., Berens, M. E., Brenner, C., & Bindra, R. S. (2019). PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma.. Nature Communications, 10 (1). http://dx.doi.org/10.1038/s41467-019-11732-6
Peer Reviewed
1
Open Access
1
