Document Type
Journal Article
Publication Date
1-23-2013
Journal
Neurobehavioral HIV Medicine
Volume
Volume 5, Issue 1
Inclusive Pages
1-10
Abstract
Tenofovir is a widely used antiretroviral medication indicated to treat adults and children infected with HIV. Current guidelines for the management of HIV infection recommend tenofovir disoproxil fumarate (TDF) as a component of the preferred first-line combination antiretroviral therapy. The efficacy, tolerability, prolonged half-life allowing for once-daily administration, and availability as a component of several fixed-dose formulations make TDF an attractive choice for treatment-naive and treatment-experienced HIV-infected patients. TDF is also widely used as a component of postexposure prophylaxis in noninfected individuals. Most importantly, it has been recently approved for use as pre-exposure prophylaxis for noninfected adults and adolescents to reduce the risk of HIV transmission. With increasing use of TDF among adults and children, understanding of the potential for drug-associated side effects is important. This review focuses on the neuropsychiatric effects of tenofovir in adults and children with HIV infection in comparison with other antiretroviral drugs.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial 3.0 License
APA Citation
Ferrer, K., & Rakhmanina, N. (2013). Neuropsychiatric effects of tenofovir in comparison with other antiretroviral drugs. Neurobehavioral HIV Medicine, 5(1), 1-10.
Peer Reviewed
1
Open Access
1
Comments
Reproduced with permission of Dove Medical Press