Document Type
Journal Article
Publication Date
11-5-2018
Journal
Biomedical Optics Express
Volume
9
Issue
12
Inclusive Pages
5962-5981
DOI
https://doi.org/10.1364/BOE.9.005962
Keywords
Endoscopy; LSCI; Laparoscopy; Bowel perfusion
Abstract
Laser speckle contrast imaging (LSCI) utilizes the speckle pattern of a laser to determine the blood flow in tissues. The current approaches for its use in a clinical setting require a camera system with a laser source on a separate optical axis making it unsuitable for minimally invasive surgery (MIS). With blood flow visualization, bowel viability, for example, can be determined. Thus, LSCI can be a valuable tool in gastrointestinal surgery. In this work, we develop the first-of-its-kind dual-display laparoscopic vision system integrating LSCI with a commercially available 10mm rigid laparoscope where the laser has the same optical axis as the laparoscope. Designed for MIS, our system permits standard color RGB, label-free vasculature imaging, and fused display modes. A graphics processing unit accelerated algorithm enables the real-time display of three different modes at the surgical site. We demonstrate the capability of our system for imaging relative flow rates in a microfluidic phantom with channels as small as 200 μm at a working distance of 1–5 cm from the laparoscope tip to the phantom surface. Using our system, we reveal early changes in bowel perfusion, which are invisible to standard color vision using a rat bowel occlusion model. Furthermore, we apply our system for the first time for imaging intestinal vasculature during MIS in a swine.
APA Citation
Cha, J., Zheng, C., & Lau, L. W. (2018). Dual-display laparoscopic laser speckle contrast imaging for real-time surgical assistance. Biomedical Optics Express, 9 (12). http://dx.doi.org/https://doi.org/10.1364/BOE.9.005962
Peer Reviewed
1
Open Access
1
Included in
Bioimaging and Biomedical Optics Commons, Biomedical Commons, Biomedical Devices and Instrumentation Commons, Pediatrics Commons, Translational Medical Research Commons