Title

Manipulating DNA damage-response signaling for the treatment of immune-mediated diseases.

Document Type

Journal Article

Publication Date

6-13-2017

Journal

Proceedings of the National Academy of Sciences of the United States of America

Volume

114

Issue

24

Inclusive Pages

E4782-4791

DOI

10.1073/pnas.1703683114

Keywords

Animals; Cell Cycle Checkpoints; DNA Damage; Disease Models, Animal; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Etoposide; Humans; Immune System Diseases; Lymphocyte Activation; Lymphohistiocytosis, Hemophagocytic; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Multiple Sclerosis; Proto-Oncogene Proteins c-mdm2; Signal Transduction; T-Lymphocytes; Tumor Suppressor Protein p53

Peer Reviewed

1

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