Document Type
Journal Article
Publication Date
3-2017
Journal
ADC Fetal and Neonatal Edition
Volume
102
Issue
2
Inclusive Pages
F167-169
DOI
10.1136/archdischild-2016-310841
Abstract
Background Worldwide, oral sucrose is standard of care in many neonatal intensive care units to relieve procedural pain in neonates. This study aims to determine if time interval between sucrose administration and heelstick correlates with pain scores.
Methods Neonates were prospectively studied with variable time intervals and assessed with the Premature Infant Pain Profile-Revised (PIPP-R).
Results 150 neonates were included with a median gestational age of 30+6 (IQR 27+6–33+2) weeks and a median time interval of 72 (IQR 39–115) seconds between sucrose administration and heelstick. In multiple regression analysis, this time interval was not significantly related to the PIPP-R (B=0.004, 95% CI −0.005 to 0.013, p=0.37). Providing non-nutritive sucking combined with sucrose was significantly related to lower PIPP-R scores (B=−3.50, 95% CI −4.7 to −2.3, p<0.001).
Conclusions Our study suggests that there is no need to wait 2 min after sucrose administration before a painful procedure. Sucrose-induced non-nutritive sucking shows a fast pain-relieving effect in neonates.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License
APA Citation
Meesters, N., Simons, S., van Rosmalen, J., Reiss, I., van den Anker, J., & van Dijk, M. (2017). Waiting 2 minutes after sucrose administration—unnecessary?. ADC Fetal and Neonatal Edition, 102 (2). http://dx.doi.org/10.1136/archdischild-2016-310841
Peer Reviewed
1
Open Access
1
Comments
Reproduced with permission of BMJ Publishing Group. ADC Fetal and Neonatal Edition