Real-time, label-free, intraoperative visualization of peripheral nerves and microvasculatures using multimodal optical imaging techniques

Authors

Jaepyong Cha, George Washington University
A Broch
S Mudge
K Kim
J Namgoong
E Oh
P Kim

Document Type

Journal Article

Publication Date

2018

Journal

Biomedical Optics Express

Volume

9

Issue

3

DOI

10.1364/BOE.9.001097

Abstract

Accurate, real-time identification and display of critical anatomic structures, such as the nerve and vasculature structures, are critical for reducing complications and improving surgical outcomes. Human vision is frequently limited in clearly distinguishing and contrasting these structures. We present a novel imaging system, which enables noninvasive visualization of critical anatomic structures during surgical dissection. Peripheral nerves are visualized by a snapshot polarimetry that calculates the anisotropic optical properties. Vascular structures, both venous and arterial, are identified and monitored in real-time using a near-infrared laser-speckle-contrast imaging. We evaluate the system by performing in vivo animal studies with qualitative comparison by contrast-agent-aided fluorescence imaging.

Comments

© 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.

APA Citation

Cha, J., Broch, A., Mudge, S., Kim, K., Namgoong, J., Oh, E., & Kim, P. (2018). Real-time, label-free, intraoperative visualization of peripheral nerves and microvasculatures using multimodal optical imaging techniques. Biomedical Optics Express, 9 (3). http://dx.doi.org/10.1364/BOE.9.001097

Open Access

1