Document Type
Journal Article
Publication Date
12-2017
Journal
Molecular Genetics and Metabolism Reports
Volume
13
Inclusive Pages
52-54
DOI
10.1016/j.ymgmr.2017.04.001
Abstract
Fibroblast growth factor-21 (FGF21) levels are elevated in patients with primary mitochondrial disorders but have not been studied in patients with inborn errors of metabolism (IEM) known to have secondary mitochondrial dysfunction. We measured plasma FGF21 by ELISA in patients with and without IEM. FGF21 levels were higher in patients with IEM compared to without IEM (370 pg/dL vs. 0–65 pg/dL). Further study of FGF21 as a biomarker in IEM is warranted.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
APA Citation
Kirmse, B., Cabrera-Luque, J., Ayyub, O., Cusmano-Ozog, K., Chapman, K. A., & Summar, M. L. (2017). Plasma fibroblast growth factor-21 levels in patients with inborn errors of metabolism. Molecular Genetics and Metabolism Reports, 13 (). http://dx.doi.org/10.1016/j.ymgmr.2017.04.001
Peer Reviewed
1
Open Access
1
Comments
Reproduced with permission of Elsevier B.V. Molecular Genetics and Metabolism Reports