A Subtrochanteric Femoral Stress Fracture following Bisphosphonate Treatment in an Adolescent Girl

Document Type

Journal Article

Publication Date

2-1-2017

Journal

Hormone Research in Paediatrics

Volume

87

Issue

1

DOI

10.1159/000447425

Keywords

Atypical subtrochanteric and diaphyseal femoral fractures; Bisphosphonates

Abstract

© 2016 S. Karger AG, Basel. Atypical subtrochanteric and diaphyseal femoral fractures (AFFs) have emerged as a potential complication of bisphosphonate treatment in adults. Despite increasing off-label use of bisphosphonates in children and adolescents for a variety of skeletal disorders, there have been no reports of AFFs in children or adolescents outside of the osteogenesis imperfecta population. We present the case of a 16-year-old girl who developed a subtrochanteric femoral stress fracture following pamidronate treatment for idiopathic juvenile osteoporosis.

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