Asymmetric intraocular pressure in sphenoid wing meningioma patients

Document Type

Journal Article

Publication Date



Investigative Ophthalmology and Visual Science






Purpose. To determine the prevalence and associated features of asymmetric intraocular pressure in patients with sphenoid wing meningiomas. Methods. A retrospective chart review of 70 sphenoid wing meningiomas was performed. 52 patients had pre-operative intraocular pressure documentation available for review. Results. 21 of the 52 (40%) patients had a higher intraocular pressure on the side of the tumor (the remainder had equal, normal IOP). The median elevation was 4mmHg (range 2-14). The median age was 55 years old (range: 35-72) in 7 men and 14 women (all Caucasian). One had a family history of glaucoma and 50% had at least one risk factor for glaucoma [myopia(4), HTN(7), DM(2), hypothyroidism without orbitopathy(5)]. All had tumor extension into the orbit with orbitals signs (proptosis, temporal fullness, dysmotility). 8/21 (38%) had unilateral ocular hypertension (IOP>22). Three of these 8 had been placed on Timoptic without recognition of the tumor (one had an enlarged cup to disc ratio and all had visual field defects). Conclusions. Asymmetry of intraocular pressure is a common finding in patients with sphenoid wing meningiomas when orbital extension is present. Orbital symptoms and signs should be sought in all cases of asymmetric intraocular pressure elevation.

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