Document Type
Journal Article
Publication Date
2-2017
Journal
Oncotarget
Volume
8
Issue
9
Inclusive Pages
15977-15995
DOI
10.18632/oncotarget.13304
Abstract
Over the past decade, cold atmospheric plasma (CAP), a near room temperature ionized gas has shown its promising application in cancer therapy. Two CAP devices, namely dielectric barrier discharge and plasma jet, show significantly anti-cancer capacity over dozens of cancer cell lines in vitro and several subcutaneous xenograft tumors in vivo. In contrast to conventional anti-cancer approaches and drugs, CAP is a selective anti-cancer treatment modality. Thus far establishing the chemical and molecular mechanism of the anti-cancer capacity of CAP is far from complete. In this review, we provide a comprehensive introduction of the basics of CAP, state of the art research in this field, the primary challenges, and future directions to cancer biologists.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
APA Citation
Yan, D., Sherman, J., & Keidar, M. (2017). Cold atmospheric plasma, a novel promising anti-cancer treatment modality.. Oncotarget, 8 (9). http://dx.doi.org/10.18632/oncotarget.13304
Peer Reviewed
1
Open Access
1
Comments
Reproduced with permission of Impact Journals LLC. Oncotarget