Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood-brain barrier

Authors

Daren Wang
Salim S. El-Amouri
Mei Dai
Chia-Yi Kuan
David Y. Hui
Roscoe O. Brady, George Washington UniversityFollow
Dao Pan

Document Type

Journal Article

Publication Date

2-2013

Journal

Proceedings of the National Academy of Sciences (USA)

Volume

Volume 110, Issue 8

Inclusive Pages

2999-3004

Keywords

Apolipoproteins E--metabolism; Blood-Brain Barrier; Lysosomes--enzymology; Protein Engineering; Receptors, LDL--metabolism

Comments

This is a PubMed Central article. Click on link for full-text access.

APA Citation

Wang, D., El-Amouri, S.S., Dai, M., Kuan, C.Y., Hui, D.Y., Brady, R.O., Pan, D. (2013). Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood-brain barrier. Proceedings of the National Academy of Sciences, 110(8), 2999-3004.

Peer Reviewed

1

Open Access

1