Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms.

Authors

Anne T Berg
Samya Chakravorty
Sookyong Koh
Zachary M Grinspan
Renée A Shellhaas
William D Gaillard, George Washington UniversityFollow
+several additional authors

Document Type

Journal Article

Publication Date

1-1-2018

Journal

PLoS One

Volume

13

Issue

3

DOI

10.1371/journal.pone.0193599

Abstract

Infantile spasms are the defining seizures of West syndrome, a severe form of early life epilepsy with poorly-understood pathophysiology. We present a novel comparative analysis of infants with spasms versus other seizure-types and identify clinical, etiological, and molecular-genetic factors preferentially predisposing to spasms. We compared ages, clinical etiologies, and associated-genes between spasms and non-spasms groups in a multicenter cohort of 509 infants (

Comments

Reproduced with permission of PLoS ONE

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 License.

APA Citation

Berg, A., Chakravorty, S., Koh, S., Grinspan, Z., Shellhaas, R., Gaillard, W., & +several additional authors (2018). Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms.. PLoS One, 13 (3). http://dx.doi.org/10.1371/journal.pone.0193599

Peer Reviewed

1

Open Access

1