Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells.

Authors

Nigora Mukhamedova
Anh Hoang
Dragana Dragoljevic
Larisa Dubrovsky, George Washington University
Tatiana Pushkarsky, George Washington University
Hann Low
Michael Ditiatkovski
Ying Fu
Ryunosuke Ohkawa
Peter J. Meikle
Anelia Horvath, George Washington University
Beda Brichacek, George Washington University
Yury I. Miller
Andrew Murphy
Michael Bukrinsky, George Washington University
Dmitri Sviridov

Document Type

Journal Article

Publication Date

7-25-2019

Journal

PLoS Pathogens

Volume

15

Issue

7

Inclusive Pages

e1007907

DOI

10.1371/journal.ppat.1007907

Keywords

ATP Binding Cassette Transporter 1; Animals; Bystander Effect; Cholesterol; Exosomes; HEK293 Cells; HIV Infections; HIV-1; Humans; Inflammation; Membrane Microdomains; Mice; Mice, Inbred C57BL; Models, Biological; RAW 264.7 Cells; Recombinant Proteins; Toll-Like Receptor 4; Triggering Receptor Expressed on Myeloid Cells-1; cdc42 GTP-Binding Protein; nef Gene Products, Human Immunodeficiency Virus

APA Citation

Mukhamedova, N., Hoang, A., Dragoljevic, D., Dubrovsky, L., Pushkarsky, T., Low, H., Ditiatkovski, M., Fu, Y., Ohkawa, R., Meikle, P. J., Horvath, A., Brichacek, B., Miller, Y. I., Murphy, A., Bukrinsky, M., & Sviridov, D. (2019). Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells.. PLoS Pathogens, 15 (7). http://dx.doi.org/10.1371/journal.ppat.1007907

Peer Reviewed

1

Open Access

1