Document Type
Journal Article
Publication Date
10-2015
Journal
Diabetic Medicine
Volume
32
Issue
10
Inclusive Pages
1342–1345
DOI
10.1111/dme.12789
Abstract
Aims
To investigate the renal effects of fitness in people with diabetes with mild renal dysfunction.
Methods
The effect of a 12-week exercise programme on estimated GFR in 128 people with diabetes was evaluated.
Results
All cardiometabolic variables improved after 12 weeks of supervised exercise. Although there was a modest 3.9% increase in estimated GFR from baseline in the 128 people who completed the study, those with baseline chronic kidney disease stages 2 and 3 were found to have significant (6 and 12%, respectively; p < 0.01) improvements in post-exercise estimated GFR. Moreover, 42% of the people with chronic kidney disease stage 3 improved to chronic kidney disease stage 2 after the intervention.
Conclusion
Short-term exercise improves renal function in those with more moderate baseline chronic kidney disease. Thus, renal function appears to be responsive to enhanced physical fitness. Being a strong and modifiable risk factor, enhanced fitness should be considered a non-pharmacological adjunct in the management of diabetic kidney disease.
Creative Commons License
This work is free of known copyright restrictions.
APA Citation
Epub ahead of print
Peer Reviewed
1
Open Access
1
Included in
Endocrine System Diseases Commons, Endocrinology, Diabetes, and Metabolism Commons, Nephrology Commons
Comments
Originally published by John Wiley & Sons. Diabetic Medicine
This article is a U.S. Government work and is in the public domain in the USA.