Transcatheter mitral valve thrombosis: A case report and literature review

Document Type

Journal Article

Publication Date

1-1-2020

Journal

Catheterization and Cardiovascular Interventions

DOI

10.1002/ccd.29374

Keywords

imaging TTE/TEE; mitral valve disease percutaneous intervention; percutaneous valve therapy; thromboprophylaxis; transcatheter valve implantation

Abstract

© 2020 Wiley Periodicals LLC Transcatheter mitral valve replacement (TMVR) is an exciting alternative therapy for complex patients with mitral valve disease. Experience with TMVR is new and there is a lot yet to discover about their durability, long-term outcomes, and complications including mitral transcatheter heart valve (THV) thrombosis. Many factors have been speculated to increased risk of THV thrombosis. Here, we report a case of a 72-year-old woman who developed mitral THV thrombosis after undergoing TMVR for severe mitral regurgitation with mitral annular calcification. We reviewed 42 TMVR papers with 1,484 patients, including 60 with mitral THV thrombosis. We discussed the most common strategies used for mitral THV thromboprophylaxis and treatment.

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