Prostatic secretion microbiota: A comparative analysis of the Сhronical prostatitis ii and iiia category

Document Type

Journal Article

Publication Date

1-1-2020

Journal

Urologiia

Volume

2020

Issue

2

DOI

10.18565/urology.2020.2.16-22

Keywords

Bacterial prostatitis; Chronic prostatitis/chronic pelvic pain syndrome IIIa; Comparison; Microbiota; Prostate secretion

Abstract

© 2020, Bionika Media Ltd.. All rights reserved. Background. Chronic bacterial prostatitis (CBP) and chronic prostatitis/chronic pelvic pain syndrome IIIa (CP/CPPS IIIa) are separate nosologies defined diagnostic verification criteria according to the NIH-NIDDK classification (1995). The identification of enterobacteria in the prostatic secretion (PS) has long been a criterion for the diagnosis of CBP, while PS in patients suffering CP/CPPS IIIa was considered as “sterile”. However, the introduction of various methods of PS`s in-depth analysis and UPOINTS classification (2010) development with the allocation of site I (infection) allows us to consider the infectious factor as an etiological predictor of the initiation of inf lammation in the prostate with CP/CPPS IIIa. Thus, the determination of the features of the taxonomic composition of microbiota in СBP and CP/CPPS IIIa can act as a differentiating factor of these conditions. Aims/Objective: performing a comparative analysis of the PS microbiota in patients suffering from CBP and CP/CPPS IIIa. is unverified CBP, which in turn necessitates a review of diagnostic and therapeutic strategies to achieve positive clinical result.

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