Output of endogenous monoamine oxidase inhibitor in rats: Effect of ethanol, tryptamine and tryptophan

Document Type

Journal Article

Publication Date

3-1-1983

Journal

Journal of Neural Transmission

Volume

56

Issue

1

DOI

10.1007/BF01243376

Abstract

Contrary to prediction, loading rats with tryptamine, tryptophan or methanol failed to produce any rise in endogenous monoamine oxidase inhibitor output, whilst ethanol administration resulted in a significantly decreased excretion. These findings, which provide no support for the hypothesis that the inhibitor is a β-carboline, may shed some light on the tranquillizing effect of ethanol in man. © 1983 Springer-Verlag.

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