Noonan's Syndrome and Seminoma of Undescended Testicle

Authors

Anita Aggarwal, Washington Cancer Institute
Jayashree Krishnan, Washington Cancer Institute
Arnold Kwart, Washington Cancer Institute
David Perry, Washington Cancer Institute

Document Type

Journal Article

Publication Date

1-1-2001

Journal

Southern Medical Journal

Volume

94

Issue

4

DOI

10.1097/00007611-200104000-00016

Abstract

A 26-year-old white man with Noonan's syndrome and a history of lifetime lymphedema had had bilateral orchiopexy for undescended testicles at the age of 12. He noticed increased swelling of the right testicle confirmed by ultrasonography as a solid mass. Computed tomography of the abdomen and pelvis showed multiple enlarged mesenteric and retroperitoneal lymph nodes. At right inguinal orchiectomy, pathologic findings were consistent with seminoma of the right testicle. Postoperatively, he was treated with four cycles of cisplatin and etoposide. A case of nonseminoma in Noonan's syndrome has been reported previously, but this is first case report of seminoma in a patient with Noonan's syndrome.

APA Citation

Aggarwal, A., Krishnan, J., Kwart, A., & Perry, D. (2001). Noonan's Syndrome and Seminoma of Undescended Testicle. Southern Medical Journal, 94 (4). http://dx.doi.org/10.1097/00007611-200104000-00016