Etravirine induced severe hypersensitivity reaction and fulminant hepatitis: A case report and review of the literature.

Authors

Linda Nabha, Georgetown University
Gayle P. Balba, Georgetown University
Princy N.S. Kumar, Georgetown University
Carmelita Tuazon, George Washington Univeristy

Document Type

Journal Article

Publication Date

2012

Journal

Journal of AIDS and clinical research

Volume

Volume 3, Special Issue 2

Abstract

We report the first published case of etravirine induced hypersensitivity reaction leading to fulminant hepatic failure in a 49-year-old female patient with Human Immunodefi ciency Virus. She presented with a life threatening rash and end stage organ damage requiring intensive care unit supportive care. Liver biopsy supported the diagnosis of drug-induced hypersensitivity. The patient recovered after withdrawal of etravirine and the use of systemic corticosteroids. The authors describe etravirine drug hypersensitivity as a clinically important reaction and that early recognition can improve survival.

Comments

Reproduced with permission from OMICS Publishing Group, Journal of AIDS and Clinical Research.

Creative Commons License

This work is licensed under a Creative Commons Attribution 3.0 License.

APA Citation

Nabha, L., Balba, G. P., Tuazon, C., & Kumar, P. N. (2012). Etravirine induced severe hypersensitivity reaction and fulminant hepatitis: A case report and review of the literature. Journal of AIDS and Clinical Research, 3(SPL ISSUE2).

Open Access

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