Document Type
Journal Article
Publication Date
1-1-2017
Journal
Clinical Cosmetic and Investigational Dermatology
Volume
10
Inclusive Pages
289-298
DOI
10.2147/CCID.S142450
Abstract
Microneedling (MN) is a novel therapeutic modality in dermatology. Through physical trauma from needle penetration, MN induces a wound healing cascade with minimal damage to the epidermis. This allows for enhancement in the absorption of mainstay topical therapies across the thick stratum corneum. MN has become increasingly utilized over the last several years as it is a relatively simple procedure that is cost-effective, well tolerated, and offers both cosmetic and therapeutic benefits. The ability to treat localized areas of disease has led to numerous studies gauging its potential in focal diseases of inflammation, dyschromia, and photodamage. This review discusses the principles and evidence behind the expanding applications of MN. It has shown promising results as an adjuvant therapy for enhanced drug delivery in the treatment of atrophic scars, alopecia, actinic keratoses, and disorders of pigmentation such as melasma. The efficacy in treatment of vitiligo remains limited. Overall, the procedure has few adverse sequelae compared to other therapies, is highly efficacious, and is a viable resurfacing option for skin of color. Future research is needed to determine the frequency, interval, and specific device settings that foster optimal results. Additionally, large controlled trials are needed to shed light on the utility of MN as an evidence-based regimen for the treatment of various dermatologic conditions.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial 3.0 License
APA Citation
Iriarte, C., Awosika, O., Rengifo-Pardo, M., & Ehrlich, A. (2017). Review of Applications of Microneedling in Dermatology.. Clinical Cosmetic and Investigational Dermatology, 10 (). http://dx.doi.org/10.2147/CCID.S142450
Peer Reviewed
1
Open Access
1
Comments
Reproduced with permission of Dovepress. Clinical, Cosmetic and Investigational Dermatology