Cardiovascular Risk Factor Control and Lifestyle Factors in Young to Middle-Aged Adults with Newly Diagnosed Obstructive Coronary Artery Disease

Authors

Michael S. Garshick, NYU Langone Health
Georgeta D. Vaidean, NYU Langone Health
Anish Vani, NYU Langone Health
James A. Underberg, NYU Langone Health
Jonathan D. Newman, NYU Langone Health
Jeffrey S. Berger, NYU Langone Health
Edward A. Fisher, NYU Langone Health
Eugenia Gianos, Lenox Hill Hospital

Document Type

Journal Article

Publication Date

6-1-2019

Journal

Cardiology (Switzerland)

Volume

142

Issue

2

DOI

10.1159/000498891

Keywords

Accelerated atherosclerosis; Cardiovascular risk factors; Prevention; Preventive cardiology

Abstract

© 2019 S. Karger AG, Basel. Background: While progress in the prevention of cardiovascular disease (CVD) has been noted over the past several decades, there are still those who develop CVD earlier in life than others. Objective: We investigated traditional and lifestyle CVD risk factors in young to middle-aged patients compared to older ones with obstructive coronary artery disease (CAD). Methods: A retrospective analysis of patients with a new diagnosis of obstructive CAD undergoing coronary intervention was performed. Young to middle-aged patients were defined as those in the youngest quartile (n = 281, mean age 50 ± 6 years, 81% male) compared to the other three older quartiles combined (n = 799, mean age 69 ± 7.5 years, 71% male). Obstructive CAD was determined by angiography. Results: Young to middle-aged patients compared to older ones were more likely to be male (p < 0.01), smokers (21 vs. 9%, p < 0.001), and have a higher body mass index (31 ± 6 vs. 29 ± 6 kg/m2, p < 0.001). Younger patients were less likely to eat fruits, vegetables, and fish and had fewer controlled CVD risk factors (2.7 ± 1.2 vs. 3.0 ± 1.0, p < 0.001). Compared to older patients, higher levels of psychological stress (aOR 1.6, 95% CI 1.1-2.4), financial stress (aOR 1.8, 95% CI 1.3-2.5), and low functional capacity (aOR 3.3, 95% CI 2.4-4.5) were noted in the young to middle-aged population as well. Conclusion: Lifestyle in addition to traditional CVD risk factors should be taken into account when evaluating risk for development of CVD in a younger population.

APA Citation

Garshick, M., Vaidean, G., Vani, A., Underberg, J., Newman, J., Berger, J., Fisher, E., & Gianos, E. (2019). Cardiovascular Risk Factor Control and Lifestyle Factors in Young to Middle-Aged Adults with Newly Diagnosed Obstructive Coronary Artery Disease. Cardiology (Switzerland), 142 (2). http://dx.doi.org/10.1159/000498891