Perioperative Applications of Therapeutic Plasma Exchange in Cardiac Surgery: A Narrative Review
Journal of Cardiothoracic and Vascular Anesthesia
cardiac surgery; coagulation; immunology; plasma exchange
Therapeutic plasma exchange (TPE) has a number of applications in cardiac surgical patients and has been used increasingly in high-risk heart and lung transplant patients. In this narrative review, the authors describe TPE principles, complications, and specific indications for TPE, including thrombotic thrombocytopenic purpura, heparin-induced thrombocytopenia, induction of immunotolerance in heart and lung transplant patients, and treatment of antibody-mediated rejection in heart and lung transplant patients. The review is based on published literature and the authors’ institutional experience with perioperative TPE in cardiac surgical patients.
Grazioli, A., Athale, J., Tanaka, K., Madathil, R., Rabin, J., Kaczorowski, D., & Mazzeffi, M. (2020). Perioperative Applications of Therapeutic Plasma Exchange in Cardiac Surgery: A Narrative Review. Journal of Cardiothoracic and Vascular Anesthesia, 34 (12). http://dx.doi.org/10.1053/j.jvca.2020.01.054