One-Year Efficacy of OMNI Canaloplasty With and Without Additional Hydrus Microstent During Cataract Surgery

Document Type

Journal Article

Publication Date

4-8-2026

Journal

Journal of glaucoma

DOI

10.1097/IJG.0000000000002722

Keywords

canaloplasty; glaucoma medications; intraocular pressure; microinvasive glaucoma surgery; microstent

Abstract

PRECIS: After one year, OMNI canaloplasty with or without Hydrus Microstent achieved comparable surgical outcomes, reductions in IOP, and medication reduction. PURPOSE: This study compares the one-year effectiveness of performing a canaloplasty during concurrent cataract surgery (CS) with or without a microstent in patients with glaucoma. METHODS: A retrospective analysis was performed on 66 eyes: 33 received OMNI canaloplasty and 33 received OMNI canaloplasty with additional Hydrus Microstent during CS. The mean number of ocular hypotensive medications and intraocular pressure (IOP) were assessed after one year. The primary outcome was surgical success, defined as attaining the target IOP without additional medications or procedures. Eyes were matched (1:1) based on demographics and disease characteristics. Statistical analysis included paired t-tests and regression modeling. RESULTS: Mean IOP at one year was reduced by 18.0% in the canaloplasty alone group and by 12.8% in the canaloplasty with microstent group (P=0.445). Mean medications at one year were reduced by 47.8% in the canaloplasty alone group and by 60.0% in the canaloplasty with microstent group (P=0.554). Surgical success at one year was 75.8% for canaloplasty alone and 87.9% for canaloplasty with microstent (P=0.339). The total adverse event rate was 9.09% (n=6). CONCLUSION: Combining canaloplasty with a microstent did not yield statistically significant improvements in surgical success, IOP reduction, medication use, or safety outcomes at one year compared to standalone canaloplasty. This suggests that for patients undergoing CS with concurrent canaloplasty, the addition of a microstent may not confer substantial long-term clinical benefit. Small cohort size and differences in population between groups may also affect this outcome.

Department

School of Medicine and Health Sciences Student Works

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